Obstetric Analgesia and Anesthesia A Manual for Physicians, Nurses and Other Health Personne4 Prepared for the World Federation of Societies of Anaesthesiologists Edited by John J. Bonica With 24 Figures Springer-Verlag Berlin· Heidelberg· New York 1972 M. D. JOHN J. BONICA, University of Washington, School of Medicine, Department of Anesthe siology and Anesthesia Research Center, Seattle/USA Chairman, Ad Hoc Committee for Obstetric Anesthesia, and Scientific Advisory Committee WFSA ISBN 978-3-642-49523-6 ISBN 978-3-642-49813-8 (eBook) DOl 10.1007/978-3-642-49813-8 The use of general descriptive names, trade marks, etc. in this publication, even if the former are not especially identified, is not to be taken as a, sign that such names, as understood by the Trade Marks and Merchandise Marks Act, may accordingly be used freely by anyone. This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically those of translation, reprinting, re-use of illustrations, broadcasting, repro duction by photocopying, machine or similar means, and storage in data banks. Under § 54 of the German Copyright Law where copies are made for other than private use, a fee is payable to the publisher, the amount of the fee to be determined by agreement with the publisher. © by Springer-Verlag Berlin. Heidelberg 1972. Library of Congress Catalog Card Number 72-86713. Introduction The provision of the best possible anesthetic care to the-greatest number of patients all over the world has always been the main goal of the World Federation of Societies of Anaesthesiologists. In addition to the establishment of Regional Anesthesiology Training Centers and the organization of Regional and World Congresses, the distribution of practical monographs on some important aspects of anesthesiology were considered important for the attainment of this objective. In 1968, on the occasion of the Fourth World Congress of Anesthesiology, held in London, a monograph on "Emergency Resuscitation", compiled by the Committee on Cardiopulmonary Resuscitation, chaired by Professor HENNING POULSEN, was made available to our membership. Subsequent ly, this excellent monograph was translated into Spanish, Russian, Ger man and French and to this date over 100,000 copies of it have been distributed to anesthesiologists and other interested physicians the world over. When looking for a suitable topic for a second monograph to commem orate the 1972 World Congress of Anesthesiology to be held in Kyoto this September, the subject of Obstetric Analgesia and Anesthesia was the first choice of almost everyone consulted. For reasons that are hard to condone, obstetric analgesia and anesthesia has often been the step child among the anesthetic subspecialties. Considering that one fourth to one third of all anesthesias administered are for the relief of child birth, that obstetric anesthesia is in many cases "emergency" anesthesia, and that not one but two lives are at stake, it is difficult to acquiesce in the fact that in many communities this important function, deserving the skill and devotion of the best specialists, is often relegated to poorly trained medical and paramedical personnel. In an attempt to alleviate this deplorable situation, an Ad Hoc Com mittee for Obstetric Anesthesia was appointed and charged with the task of compiling a brief, but comprehensive, practical monograph on obstetric pain relief and infant resuscitation. This monograph is the result of many hours of hard work contributed by the members of this committee, ably directed by Professor John Bonica. It is our hope that this concise volume will accomplish two objectives: It will arouse a world wide interest in the sadly neglected field of obstetric anesthesia and will serve as a practical guide for those planning to devote more III time, energy and sophistication to the relief of the suffering of parturients and the improvement of chances of the newborn for a healthier and thereby happier life. FRANCIS F. FOLDES, M. D. President World Federation of Societies of Anaesthesiologists IV Preface In recent years there has been an impressive surge of interest in obstetric analgesia and anesthesia. This trend is exerting social and professional pressures on physicians to provide parturients with better and more wide spread pain relief during childbirth. Of the many factors for this trend for greater demand for, and use of, anesthesia for childbirth, one of the most important: has been the expectation of parturients. Today, gravidas in many countries, having been made aware of the benefits of good ob stetric analgesia by magazine articles, books, television and other news media, have come to expect it just as they expect painless surgery and painless dentistry. Thisincreased demand by patients and the realization that lack of anesthesia or poorly administered anesthesia in themselves cause maternal and perinatal mortality and morbidity have prompted obstetricians in many parts of the world to demand better services by anesthesiologists. This expectation is strongly supported by statistics from those medical centers where obstetric anesthesia is provided by competent personnel. These data show that optimal pain relief not only does not contribute to, but actually reduces maternal and perinatal mortality and morbidity by permitting better obstetric care. In response to this, more and more physician-anesthetists are devoting some of their professional time to obstetric anesthesia and some have become "obstetric anesthesio logists," physicians with special training who are devoting all of their efforts to this field. This booklet is intended to provide guidelines to people who have the serious responsibility of administering obstetric analgesia-anesthesia, whether they be physicians, nurses or midwives. The importance of fun damental knowledge in managing parturients cannot be overemphasized, and is attested by the rather large amount of space devoted to Chapter 1. Since normal vaginal delivery occurs in over three-fourths of births, a commensurate amount of space is devoted to this aspect of obstetrics. The sections on operative and complicated deliveries consider only the most common problems. The scope of the brochure and space limitations pre clude discussion of every drug and technique used throughout the world or detailed review of the literature of the methods mentioned. The refer ence list at the end of the brochure should be consulted for comprehensive reviews. v I wish to thank the members of the Ad Hoc Committee, but especially Doctors Gertie Marx and Sol Shnider, for their cooperation and help in the development of this brochure. The Committee hopes that it will en courage better anesthetic care for mothers and their offspring everywhere. Seattle, June 1972 JOHN J. BONICA, M. D. Chairman, Ad Hoc Committee for Obstetric Anesthesia, and Scientific Advisory Committee WFSA VI Table of Contents Part A. Fundamental Considerations Chapter 1. Physiologic and Pharmacologic Considerations 1 Maternal Physiology and Psychology 1 Physiology and Pharmacology of the Placenta and Fetus ................... 14 Physiology of the Forces of Labor ....... 21 Pharmacology of Obstetric Analgesics, Anesthe- tics and Related Drugs ............. 23 Part B. Analgesia-Anesthesia for Normal Labor and Vaginal Delivery Chapter 2. General Considerations 29 Basic Principles 29 Antepartal Preparation 30 Preanesthetic Care 34 Intraanesthetic Care 35 Postanesthetic Care 35 Chapter 3. Non-Pharmacologic Methods of Obstetric Anal- geSIa ......... 36 Psychologic Analgesia . . . . . 36 Acupuncture Analgesia . . . . . 42 Chapter 4. Simple Methods of Obstetric Analgesia 43 Management During Latent Phase . 43 Analgesia During the Active Phase of Labor 45 Chapter 5. Regional Analgesia-Anesthesia 48 Basic Considerations 49 Paracervical Block '. . . . . 54 Pudendal Block ...... 56 Subarachnoid (Spinal) Anesthesia 58 Spinal Epidural Block ...... 60 Caudal Block . . . . . . . . . . . 68 Cqp1plications of Regional Anesthesia 70 Chapter 6. General Analgesia-Anesthesia 75 Basic Considerations 75 Inhalation Analgesia 77 General Anesthesia . 82 VII Part C. Analgesia-Anesthesia for Complicated Obstetrics Chapter 7. Anesthesia for Operative Vaginal Delivery 87 Forceps Delivery 87 Breech Delivery .......... . 89 Multiple Delivery ......... . 92 Other Operative Obstetric Procedures 93 Chapter 8. Anesthesia for Cesarean Section 95 Elective Cesarean Section ..... . 95 Emergency Cesarean Section 100 Chapter 9. Anesthesia in the Presence of Complications 102 Toxemia of Pregnancy 102 Heart Disease 107 Diabetes Mellitus 111 Prematurity 113 Fetal Distress .. 114 Chapter 10. Management of Newborn 117 Basic Considerations 117 General Management 120 Resuscitation of the Depressed Newborn 122 References. . 127 VIII Part A. Fundamental Considerations Chapter 1. Physiologic and Pharmacologic Considerations To provide optimal obstetric anesthetic care, it is essential for the anesthetistl to kI,loW well the maternal physiologic alterations pro duced by pregnancy, labor and parturition; physiology and pharma cology of 'the fetal placental complex, and of the forces of labor and how these are altered by analgesics and anesthetics. Unless this knowl edge is properly applied, the anesthetist may make a grevious error which may prove disastrous to the n:tother or the newborn or both. This chapter includes a summary of current knowledge on: a) ma ternal, physiologic and psychologic changes produced by pregnancy and parturition; b) physiology and pharmacology of the placenta and fetus; c) the physiology and pharmacology of the forces of labor. A summary of the physiology of the newborn is contained in Chapter 10. Maternal Physiology and Psychology The process of pregnancy, labor and delivery produces remarkable physiologic as well as psychologic changes in the mother. From the viewpoint of the anesthetist, the changes involving respiration, circu lation, acid-base and electrolyte balance, and gastrointestinal function are the most important. These are consequent to hormones produced by the placenta or are due to mechanical effects of the growing uterus or both. Respiration Pregnancy produces impressive anatomic and physiologic changes in volving the patient's airway, lung volumes, ventilation and the dy namics of breathing. Throughout this volume this term will be used to denote the person who admin isters the anesthetic, whether he be a trained physician (anesthesiologist), registered nurse anesthetist or other allied health personnel. 1 Anatomic changes. In the majority of pregnant women, capillary en gorgement takes place throughout the respiratory tract so that the naso pharynx, larynx, trachea and bronchi become swollen and reddened. These changes simulate inflammation and often cause changes in the voice and make nose breathing difficult for some women at term. They are markedly aggravated in the presence of even minor upper respir atory infection and toxemia of pregnancy. The growing uterus causes the diaphragm to rise 4 cm, but does not impair its excursions and, in fact, this is greater in pregnancy than in the puerperium. The abdominal muscles have much less tone and are less active in the pregnant than in the non-pregnant state. The cephalad displacement of the diaphragm is effectively counterbalanced by an increase of 2 cm in the anterior posterior and transverse diameters. of the thoracic cage and flaring of the ribs all resulting in a 5 -7 cm increase in the circumference of the thoracic cage. X-rays show increased lung markings which simulate mild congestive failure. Lung Volume. Lung volumes do not change until the fifth month of gestation, after which there is a progressive decrease in expiratory re serve volume (ERV), residual volume (RV), and functional residual capacity (FRC). At term, ERV is about 100 mlless, and RV 200 ml less than in the non-pregnant state. Consequently, FRC is about 300 ml or 20 per cent lower than in the non-pregnant state. These changes are accentuated by the recumbent position, obesity, and mitral valve dis ease. The inspiratory capacity (IC) and the inspiratory reserve volume (IRV) increase concomitantly with the result that total lung capacity (TLC) remains unaltered. Vital capacity (VC) remains unaltered, but occasionally increases. Maximum breathing capacity (MBC is little affected by pregnancy as are timed vital capacity, peak flow rates, and the velocity index. Lung compliance is unaffected, but total pulmo nary resistance is significantly lower during pregnancy, primarily due to decrease in airway resistance. Parturients in the supine or litho tomy positions have decreased total and chest wall compliance which rapidly increases after delivery of the infant. The mixing and distri bution of inspired gas in the lung of the gravida remains normal. Ventilation. Pregnancy is associated with a marked increase in minute ventilation which at term is 50 % above normal. This is effected by a 40 % increase in tidal volume, and 15 % increase in respiratory rate. (Fig ure 1). Since dead space remains normal, alveolar ventilation is about 70 % above normal at term. Until recently it was thought that the in crease was progressive throughout pregnancy but recent data show that almost maximum hyperventilation occurs as early as the second or third 2
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