Table Of Content

INDEX OF SUBJECTS acrodermatitis enteropathica, zinc deficiency 164 bones adhesins, bacterial 235-240 effects of amenorrhoea 81-82 adiposity see obesity effects of diet and physical exercise in women aflatoxins 80-84 carcinogens 178, 182 metabolism in women athletes 80-82 effect of glucosinolates on toxicity 217-218, 222 brain structures, requirement for fatty acids 8 agglutinins, bacterial 237, 240, 246 broccoli, glucosinolates 206, 209, 214, 221 aglucones, breakdown products of glucosinolates Brussels sprouts, glucosinolates 206-207, 209, 210 213-215 alcohol dehydrogenases, xenobiotic metabolizing bulimia see eating disorders enzymes 219 alkaline phosphatase, assessment of zinc status 159 cabbage, glucosinolates 206, 209, 213-215 allergens see antigens caffeine, carcinogenesis 180—181, 185, 189 allergy calabrese, glucosinolates 206, 209, 214 definition 26 calciferol see vitamin D infant, effects of human milk 33-34 calcium materno-fetal effects on development 25-38 absorption from gut, relationship with zinc 139 amenorrhoea see menstruation effect of elimination diets on intake in mothers amino acids, effects on zinc uptake 142-145 37 anorexia see eating disorders effect on phytate inhibition of zinc absorption antibodies, materno-fetal transfer 27-28 154 antigens, materno-fetal transfer 31-32 human milk and infant formulas 12-13 antimicrobials, growth promotion in livestock 245 Campylobacter, enteritis in human beings 240 antioxidant responsive element 184 cancer see also carcinogenesis antioxidants, carcinogenesis 180-182, 184 chemically induced, effects of glucosinolates antipyrine, effect of glucosinolate derivatives 224 217-225 appetite, effect of zinc deficiency 157 metastases, prevention 192 arachidonic acid in human milk and infant formulas protective factors in plant foods 175-194 7-9 canthaxanthin see carotenoids aryl hydrocarbon hydroxylase activity, effect of caper, glucosinolates 206-207 glucosinolates 221 carbohydrates ascorbic acid see vitamin C dietary, effect on glycosylation in gut 247 ascorbigen, breakdown product of glucosinolates human milk and infant formulas 11—12 212-213 metabolism and insulin resistance 48-51 asthma, infant, effect of maternal diet 35 carbonic anhydrase, zinc constituent 130 atherosclerosis, prevention 43-60 carcinogenesis see also cancer athletes, women blocking agents 178-184 menstruation 67-86 mechanisms 176-178 nutrition 70-73 suppressing agents 186-192 atopic diseases see allergy cardiovascular disease, prevention 43-60 f-carotene in human milk and infant formulas bacteria 14-15 interactions with gut mucosa 233-251 carotenoids see also vitamin A nutritional influences 243-250 anticarcinogens 176, 180, 191-192 beef in maternal elimination diets 35 inman 96-98 benzo(a)pyrene catechin, carcinogenesis 181, 187, 191-192 carcinogen 178-179, 182, 184, 218 cauliflower, glucosinolates 206-207, 209, 214 effect of glucosinolates 220, 222 cell proliferation, inhibitors 186-190 benzyl isothiocyanate, carcinogenesis 182, 186, 193 cellular differentiation, prevention 191 bifidobacteria children establishment facilitated by breast milk 246 zinc deficiency 160-164 glycosidase activity 243 zinc intake 156-157, 161-163 use as probiotics 245-247 cholecalciferol see vitamin D biocytin see biotin cholesterol biotin in man 114-116 infant nutrition 10-11 blood group antigens 235, 238-240 plasma, factors affecting 44-48 blood pressure, relation to atherosclerosis 51-54 chromium in human milk and infant formulas 14 259 260 Index of Subjects cobalamin see vitamin B,, ethoxyresorufin deethyiation activity, effect of colic in infants 31, 36 glucosinolates 220-222 colostrum, effect on gut glycoconjugates 243 exercise, prevention of cardiovascular disease copper 43-60 absorption from gut, relationship with zinc 139-140 fats, dietary, effect on glycosylation in gut 247 dietary, effect on zinc absorption 154 fatty acids see also lipids coumarin, carcinogenesis 182-183, 185, 193 polyunsaturated, in human milk and infant cryptoxanthin see carotenoids formulas 7-9 curcumin, carcinogenesis 183, 189, 193 feedstuffs, toxicity due to dietary glucosinolates cyanocobalamin see vitamin B,, 215-217 cytochrome P450 fimbriae, bacterial 235-240 carcinogen activators 178-180, 184 fish in maternal elimination diets 35-37 xenobiotic metabolizing enzymes 219-225 flavin nucleotides see riboflavin cytotoxins, dietary 191 flavonoids, carcinogenesis 180-182, 185, 189 folate, dietary, effect on zinc absorption 154 dairy products inman_ 111-113 maternal elimination diets 35-36 folic acid see folate use as probiotics 245 foods, toxicity due to dietary glucosinolates diabetes, relation to atherosclerosis 48-49 215-217 diarrhoea free radicals, cell damage 178-181, 183, 188, effect of bacterial fimbriae 237-240, 243 190-191 effect of dietary glycan 250 fruits, sources of anticarcinogens 175-194 diet, prevention of cardiovascular disease 43-60 7,12-dimethylbenz(a)anthracene, carcinogenesis 186, germ free animals, toxicity of glucosinolate 188-189 derivatives 216 1,2-dimethylhydrazine 178, 184 gliadin diphenols, carcinogenesis 182, 190 breast milk 31 DNA repair inducers, carcinogenesis 185 materno-fetal transfer 29 docosahexaenoic acid in human milk and infant glucobrassicin, glucosinolate 208, 211, 213, formulas 7-9 218-219, 222-223 glucoiberverin, glucosinolate 213-214, 216 eating disorders in women athletes 76-80 gluconapin, glucosinolate 208, 215, 223 eczema in infants 31, 35-36 glucosinolates 205-225 egg in maternal elimination diets 35-37 bacterial metabolism 212, 225 electrophile responsive element 184 carcinogenesis, protection against 217-219 embryo mortality, effects of dietary glucosinolates food processing effects 213-215, 221, 224 215-216 occurrence 205-207 energy toxicity 215-217 balance, relation to atherosclerosis 54-58 f-glucuronidase, carcinogenesis 184-185 expenditure, women athletes 70 glutathione S-transferases intake, women athletes 70-76 carcinogenesis 181, 183-184 values for human milk 2-3 effect of glucosinolates 221, 223-225 enteritis, effect of bacterial fimbriae 237-240 glycans see mucins enzymes see alcohol dehydrogenases, aldehyde glycoconjugates dehydrogenases, aryl hydrocarbon hydroxylase dietary effects in gut 243-250 activity, cytochrome P450, epoxide hydrolases, gut surfaces 243-250 ethoxycoumarin O-deethylase activity, glycolipids see glycoconjugates ethoxyresorufin deethylation activity, glutathione glycoproteins see glycoconjugates S-transferases, monooxygenases, myrosinase, f-glycosidase, carcinogenesis 184-185 quinone reductase, sulphotransferases, glycosidases, bacterial, degradation of protective UDPglucuronyltransferases, xenobiotic mucin 243 metabolizing enzymes goitre, effect of glucosinolate derivates 215-217 epithioalkanes, breakdown products of glucosinolates goitrin, glucosinolate 215, 223 210 growth depression, effect of dietary glucosinolates epoxide hydrolases 215-217 effect of glucosinolates 221, 223 gut xenobiotic metabolizing enzymes 220 effect of glucosinolates on incidence of cancer Escherichia coli 218 effect of fimbriae on adherence to gut surfaces mucosa, bacterial interactions 233-250 236-240, 242, 250 sites of zinc absorption 137-139 effect of milk glycoconjugates 246 ethoxycoumarin O-deethylase activity, effect of haemagglutination see Escherichia coli, glucosinolates 221-224 phytohaemagglutinins Index of Subjects hair, zinc content 158 menstruation Helicobacter pylori, adherence to gut surfaces 240 effects of diet and physical exercise 67-86 horseradish, glucosinolates 206-207 effects of low energy intake 73-76 hydrocarbons, polycyclic aromatic, carcinogenesis metallothionein 177 assessment of zinc status 159 hypertensioa, relation to atherosclerosis 51-54 gene expression 132-133 zinc absorption in the gut 136-137 immune enhancement, anticarcinogenic 192 zine binding 131 immune system, effect of zinc deficiency 157, 160 milk immunity, materno-fetal effects 25-38 effect on gut glycoconjugates 243 immunoglobulin E, synthesis by fetus 33 human, model for infant formulas 1-16 immunoglobulin G, placental transfer 27-28 zinc content 156, 166-167 immunoglobulins maternal elimination diets 34, 36-37 breast milk, effects in infants 30-31 probiotic effect of oligosaccharides 245-246 human milk and infant formulas 6 protein allergy 28-29 indole-3-carbinol, carcinogenesis 180-181, 183, 189, molybdenum in human milk and infant formulas 192-193 14 indoles, breakdown products of glucosinolates monooxygenases 211-212 carcinogen activators 178-183 infant formulas 1-16 xenobiotic metabolizing enzymes 219 inositol see also phytate mucins, gut surface 235 human milk and infant formulas 15 bacterial adhesion 241-242 insulin, resistance, relation to atherosclerosis 48-51 mucosa, gut, bacterial interactions 233-250 intrinsic factor, absorption of vitamin B,, 114 nutritional influences 243-250 iron mustard, glucosinolates 206-207, 209, 214 dietary, effect on zinc absorption 154 myoinositol hexaphosphate see phytate effect on zinc absorption from the gut 139 myrosinase, breakdown of glucosinolates 207, human milk and infant formulas 13 210-211, 225 isothiocyanates aromatic, carcinogenesis 178, 182, 186, 193 NAD(P)H dehydrogenase see quinone reductase breakdown products of glucosinolates 210 nervous system, requirement for fatty acids 7 niacin in man 109-111 kale, glucosinolates 206-207, 209, 214 nicotinamide, nicotinic acid see niacin kidney, effects of dietary glucosinolates 215, 217 nitriles, breakdown products of glucosinolates 208, 213, 216 lactation nitrosamines effect of maternal elimination diets 36-37 carcinogens 177 zinc requirement 155, 166—167 effect of glucosinolate derivatives 223 lactobacilli non-protein nitrogen in human milk 7 adherence to gut mucosa 241-242 nucleotides in human milk and infant formulas use as probiotics 245 15-16 lactoferrin in human milk 5-6 nutrition f-lactoglobulin and antibodies, materno-fetal transfer effects on gut bacteria 243-250 27-30 women athletes 67-86 lactulose, use as probiotic 245 nuts in maternal elimination diets 35-37 lectins bacterial adherence to gut surfaces 241 obesity, relation to atherosclerosis 55-58 dietary, effects on gut bacteria 244, 248-250 oestrogens, cancer 189-190 leucocytes, zinc content 158-159, 164-165 oligosaccharides see also glycoconjugates, mucins lipids see also fats, fatty acids, triacylglycerol dietary, use as probiotics 250 blood, relation to atherosclerosis 4448 human milk 11-12 human milk and infant formulas 7-11 ornithine decarboxylase, carcinogenesis 187-189, lipoproteins, relation to atherosclerosis 44-48 191 lipoteichoic acid, bacterial adherence to gut surfaces ovalbumin 241 antigen in breast milk 31 liver, effects of dietary glucosinolates 215-217 materno-fetal transfer 29 lungs, effects of dietary glucosinolates 216 oxazolidinethiones, breakdown products of lutein see carotenoids glucosinolates 210 lycopene see carotenoids palmitic acid, availability to infants 9-10 maternal elimination diets and infant allergies pantothenic acid in man 116 34-38 paracetamol, effect of glucosinolate derivates 224 menadione, menaquinone see vitamin K parakeratosis in pigs 130 262 Index of Subjects Peyer’s patch, bacterial adhesion 239-240 Shigella flexneri, glycosidase activity 243 phenacetin, effect of glucosinolate derivatives 224 sialic acid see also mucins phenethyl isothiocyanate, carcinogenesis 180, 182 masking of bacterial adherence sites in gut 244 phorbol-12-O-tetradecanoate-!3-acetate responsive requirement of infants 12 element 184 sinigrin, glucosinolate 208, 212-213, 215-216, 219, phosphorus in human milk and infant formulas 222-223 13 sodium chloride, relation to hypertension 52-54 phylloquinone see vitamin K soya in maternal elimination diets 36 physical activity steroids, effects of glucosinolates 224 bone health in women 80-84 streptococci, group A, adherence to pharyngeal and menstruation 67-86 buccal cells 241 phytate see also inositol sulphotransferases, xenobiotic metabolizing enzymes anticarcinogen 187 220 zinc absorption 152-154, 156, 167 sweed, glucosinolates 206, 209, 214-215 phytohaemagglutinins, dietary, effect on gut bacteria 248-250 taste acuity, effect of zinc deficiency 157, 160 phyto-oestrogens, anticarcinogens 190, 192-194 taurine in human milk and infant formulas 15 picolinic acid, effect on zinc absorption 142, 144 12-O-tetradecanoylphorbol-13-acetate 187-189 pig thiamin in man 104-106 effect of zinc deficiency on growth 135 thiocyanates, breakdown products of glucosinolates zinc content 130-131 210, 213, 215-216 pili see fimbriae thioglucoside glucohydrolase see myrosinase polyamines, carcinogenesis 188-189 thymulin, assessment of zinc status 159 pregnancy thyroid, effects of dietary glucosinolates 215-217 effect of maternal elimination diets on infant tocopherol, tocotrienols see vitamin E allergies 36-37 tolerance, immunological 29 zine deficiency 164-166 development in neonate 32-33 zinc requirement 155, 157 translocation of bacteria, effect of malnutrition 249 probiosis, prevention of bacterial disease 245-247 triacylglycerol structure and infant requirements progoitrin, glucosinolate 208, 212-214, 222 9-10 protein kinase C, carcinogenesis 187-188 tryptophan proteinase inhibitors, carcinogenesis 187-188 conversion to niacin in man 110 proteins infant formulas 3-4 dietary, effects on glycosylation in gut 247 turnip, glucosinolates 206—207, 209, 214-215 human milk 3-7 proto-oncogenes 188 UDPglucuronosyltransferase pteroylpolyglutamates see folate carcinogenesis 183-184 pyridoxal, pyridoxamine, pyridoxine see vitamin B, xenobiotic metabolizing enzymes 219, 221, 224-225 quercetin, carcinogenesis 180-183, 189, 191, 193 urine, zinc content 158 quinone reductase carcinogenesis 181-183 vanillin, carcinogenesis 181, 185, 193 effect of glucosinolates 221, 224 vegetables consumption data 213-214 radish, glucosinolates 206-207, 209, 214 glucosinolates 205-225 rape, glucosinolates 206-207, 217 sources of anticarcinogens 175-194 rapeseed meal, toxicity from glucosinolates vegetarianism, effects in women athletes 76 215-217, 221, 223, 225 Vibrio cholerae receptors for bacterial adherence to gut surfaces colonization of villus surfaces 239 239, 242-250 probiotic effect of milk 246 retinal, retinoic acid see vitamin A visual function in infants, effects of fatty acids rhinitis, allergic, in infants, effect of maternal diet 7-9 35 vitamin A see also carotenoids riboflavin in man 106—107 dietary, effect on glycosylation in gut 247-248 Ruminococcus, glycosidase activity 243 inman 96-98 vitamin B, see thiamin Saccharomyces boulardii, control of diarrhoea 245 vitamin B, see riboflavin Salmonella enteritidis, effect of fimbriae on vitamin B, in man 107-109 pathogenicity in mice 237 vitamin B,, in man_ 113-114 Salmonella typhimurium, diarrhoeal disease in pigs vitamin C 239 carcinogenesis 179-181 salt see sodium chloride coenzyme for breakdown of glucosinolates 210 sauerkraut, glucosinolates 213-214 inman 117-119 selenium in human milk and infant formulas 14 vitamin Din man 98-100 Index of Subjects vitamin E zine (cont.) carcinogenesis 176, 179-181 body content 130 inman 100-102 catalyst 131 vitamin H see biotin complexes and chelates 140-145 vitamin K in man_ 102-104 content in foods 152-153 vitamins, availability in man 93-119 deficiency 133-135, 160-167 aetiology 151-155 weaning, abrupt, effect on resistance to bacteria 247 prevention 161-163, 165, 167 whey proteins in human milk and infant formulas 4 teratogenic effects 164 homeostasis 130 xenobiotic metabolizing enzymes 219-224 intake 153-154, 156 effects of glucosinolates 222-224 intracellular 130 xenobiotic responsive element 180 nutrition in developing countries 151-167 requirement 155-157 Yersinia enterocolitica, gastroenteritis 240, 242 infants 160-164 zeaxanthin see carotenoids lactation 166-167 zinc pregnancy 164-166 absorption 136-140 sources in diet 151-153 assessment of status 157-160 status assessment 133-135 bioavailability 141-142 structura! role in proteins 131 biology 130-145