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266 Pages·2022·11.309 MB·English
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Nutrition, Diet and Healthy Aging Edited by Emiliana Giacomello and Luana Toniolo Printed Edition of the Special Issue Published in Nutrients www.mdpi.com/journal/nutrients Nutrition, Diet and Healthy Aging Nutrition, Diet and Healthy Aging Editors EmilianaGiacomello LuanaToniolo MDPI•Basel•Beijing•Wuhan•Barcelona•Belgrade•Manchester•Tokyo•Cluj•Tianjin Editors EmilianaGiacomello LuanaToniolo UniversityofTrieste UniversityofPadova Italy Italy EditorialOffice MDPI St.Alban-Anlage66 4052Basel,Switzerland This is a reprint of articles from the Special Issue published online in the open access journal Nutrients(ISSN2072-6643) (availableat:https://www.mdpi.com/journal/nutrients/specialissues/ nutritiondietandhealthyaging). Forcitationpurposes,citeeacharticleindependentlyasindicatedonthearticlepageonlineandas indicatedbelow: LastName,A.A.;LastName,B.B.;LastName,C.C.ArticleTitle. JournalNameYear,VolumeNumber, PageRange. ISBN978-3-0365-4841-8(Hbk) ISBN978-3-0365-4842-5(PDF) ©2022bytheauthors. ArticlesinthisbookareOpenAccessanddistributedundertheCreative Commons Attribution (CC BY) license, which allows users to download, copy and build upon publishedarticles,aslongastheauthorandpublisherareproperlycredited,whichensuresmaximum disseminationandawiderimpactofourpublications. ThebookasawholeisdistributedbyMDPIunderthetermsandconditionsoftheCreativeCommons licenseCCBY-NC-ND. Contents AbouttheEditors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii EmilianaGiacomelloandLuanaToniolo Nutrition,DietandHealthyAging Reprintedfrom:Nutrients2021,14,190,doi:10.3390/nu14010190 . . . . . . . . . . . . . . . . . . . 1 NurulIzzatiMohdSuffian,SitiNur‘AsyuraAdznam,HaziziAbuSaad,YokeMunChan, ZuriatiIbrahim,NoraidaOmarandMuhammadFaizalMurat Frailty Intervention through Nutrition Education and Exercise (FINE). A Health Promotion InterventiontoPreventFrailtyandImproveFrailtyStatusamongPre-FrailElderly—AStudy ProtocolofaClusterRandomizedControlledTrial Reprintedfrom:Nutrients2020,12,2758,doi:10.3390/nu12092758 . . . . . . . . . . . . . . . . . . 5 ArnoldMarkovics,AttilaBiro´,AndreaKun-Nemes,Mo´nikaE´vaFazekas,AnnaAnitaRa´cz, MelindaPaholcsek,Ja´nosLuka´cs,La´szlo´Stu¨ndlandJuditRemenyik EffectofAnthocyanin-RichExtractofSourCherryforHyperglycemia-InducedInflammatory ResponseandImpairedEndothelium-DependentVasodilation Reprintedfrom:Nutrients2020,12,3373,doi:10.3390/nu12113373 . . . . . . . . . . . . . . . . . . 17 QinranLiu,JianjunGuo,LiangHu,NicolaVeronese,LeeSmith,LinYangandChaoCao AssociationbetweenIntakeofEnergyandMacronutrientsandMemoryImpairmentSeverity inUSOlderAdults,NationalHealthandNutritionExaminationSurvey2011–2014 Reprintedfrom:Nutrients2020,12,3559,doi:10.3390/nu12113559 . . . . . . . . . . . . . . . . . . 31 MahaHussainAlhussain,ShaeaAlkahtani,OsamaAljuhaniandSyedShahidHabib Effects of Nutrient Intake on Diagnostic Measures of Sarcopenia among Arab Men: A Cross-SectionalStudy Reprintedfrom:Nutrients2020,13,114,doi:10.3390/nu13010114 . . . . . . . . . . . . . . . . . . . 45 JinheeKim,YunhwanLee,ChangWonWon,MiKyungKim,SeungheeKye,Jee-SeonShim, SeungkookKiandJi-hyeYun DietaryPatternsandFrailtyinOlderKoreanAdults:ResultsfromtheKoreanFrailtyandAging CohortStudy Reprintedfrom:Nutrients2021,13,601,doi:10.3390/nu13020601 . . . . . . . . . . . . . . . . . . . 59 ToshikoTanaka,SameeraA.Talegawkar,YichenJin,StephaniaBandinelliandLuigiFerrucci AssociationofAdherencetotheMediterranean-StyleDietwithLowerFrailtyIndexinOlder Adults Reprintedfrom:Nutrients2021,13,1129,doi:10.3390/nu13041129 . . . . . . . . . . . . . . . . . . 69 Ana Moradell, A´ngel Iva´n Ferna´ndez-Garcı´a, David Navarrete-Villanueva, Lucı´a Sagarra-Romero, Eva Gesteiro, Jorge Pe´rez-Go´mez, Irene Rodrı´guez-Go´mez, Ignacio Ara, Jose A. Casaj u´s, Germa´n Vicente-Rodrı´guez and Alba Go´mez-Cabello Functional Frailty, Dietary Intake, and Risk of Malnutrition. Are Nutrients Involved in Muscle Synthesis the Key for Frailty Prevention? Reprintedfrom:Nutrients2021,13,1231,doi:10.3390/nu13041231 . . . . . . . . . . . . . . . . . . 79 Chwan-LiShen,SivapriyaRamamoorthy,GurvinderKaur,JannetteM.Dufour,RuiWang, HuanbiaoMoandBruceA.Watkins Dietary Annatto-Extracted Tocotrienol Reduces Inflammation and Oxidative Stress, and ImprovesMacronutrientMetabolisminObeseMice:AMetabolicProfilingStudy Reprintedfrom:Nutrients2021,13,1267,doi:10.3390/nu13041267 . . . . . . . . . . . . . . . . . . 93 v Qiumin Huang, Xiaofang Jia, Jiguo Zhang, Feifei Huang, Huijun Wang, Bing Zhang, Liusen Wang, Hongru Jiang and Zhihong Wang Diet–Cognition Associations Differ in Mild Cognitive Impairment Subtypes Reprintedfrom:Nutrients2021,13,1341,doi:10.3390/nu13041341 . . . . . . . . . . . . . . . . . . 113 LarryA.Tucker FruitandVegetableIntakeandTelomereLengthinaRandomSampleof5448U.S.Adults Reprintedfrom:Nutrients2021,13,1415,doi:10.3390/nu13051415 . . . . . . . . . . . . . . . . . . 129 Dominika Jamioł-Milc, Jowita Biernawska, Magdalena Liput, Laura Stachowska and Zdzisław Domiszewski Seafood Intake as a Method of Non-Communicable Diseases (NCD) Prevention in Adults Reprintedfrom:Nutrients2021,13,1422,doi:10.3390/nu13051422 . . . . . . . . . . . . . . . . . . 147 JaquelineC.Avila,RafaelSamper-TernentandRebecaWong MalnutritionRiskamongOlderMexicanAdultsintheMexicanHealthandAgingStudy Reprintedfrom:Nutrients2021,13,1615,doi:10.3390/nu13051615 . . . . . . . . . . . . . . . . . . 165 JianZhangandAiZhao DietaryDiversityandHealthyAging:AProspectiveStudy Reprintedfrom:Nutrients2021,13,1787,doi:10.3390/nu13061787 . . . . . . . . . . . . . . . . . . 175 MarinaMart´ın, AmaiaRodr´ıguez, JavierGo´mez-Ambrosi, BeatrizRam´ırez, SaraBecerril, VictoriaCatala´n,MiguelLo´pez,CarlosDie´guez,GemaFru¨hbeckandMar´ıaA.Burrell Caloric Restriction Prevents Metabolic Dysfunction and the Changes in Hypothalamic NeuropeptidesAssociatedwithObesityIndependentlyofDietaryFatContentinRats Reprintedfrom:Nutrients2021,13,2128,doi:10.3390/nu13072128 . . . . . . . . . . . . . . . . . . 191 EmilianaGiacomelloandLuanaToniolo ThePotentialofCalorieRestrictionandCalorieRestrictionMimeticsinDelayingAging:Focus onExperimentalModels Reprintedfrom:Nutrients2021,13,2346,doi:10.3390/nu13072346 . . . . . . . . . . . . . . . . . . 205 Nikolina Jukic Peladic, Giuseppina Dell’Aquila, Barbara Carrieri, Marcello Maggio, Antonio Cherubini and Paolo Orlandoni Potential Role of Probiotics for Inflammaging: A Narrative Review Reprintedfrom:Nutrients2021,13,2919,doi:10.3390/nu13092919 . . . . . . . . . . . . . . . . . . 221 WonJang,YoonjinShinandYanghaKim DietaryPatternAccompaniedwithaHighFoodVarietyScoreIsNegativelyAssociatedwith FrailtyinOlderAdults Reprintedfrom:Nutrients2021,13,3164,doi:10.3390/nu13093164 . . . . . . . . . . . . . . . . . . 231 Katherine Marie Ottolini, Elizabeth Vinson Schulz, Catherine Limperopoulos and Nickie Andescavage Using Nature to Nurture: Breast Milk Analysis and Fortification to Improve Growth and Neurodevelopmental Outcomes in Preterm Infants Reprintedfrom:Nutrients2021,13,4307,doi:10.3390/nu13124307 . . . . . . . . . . . . . . . . . . 243 vi About the Editors EmilianaGiacomello EmilianaGiacomelloworksasanAssistantProfessorattheDepartmentofMedicine,Surgery andHealthattheUniversityofTrieste.Hermaininterestsarefocusedonthestudyofskeletalmuscle plasticityinthedifferentiationanddevelopmentofdifferentphysiologicalconditions,suchasageing. In this context, her most recent research centered on the study of the diet and calorie restriction mimetics in ageing animal models. Her research encompasses in vitro and vivo studies, which includecellculture,animalmodelsandhumantissues. Shespecializesinthecharacterizationofthe skeletalmusclecellsusinghistomorphologymethodologies. Shehasexpertiseintheapplicationof conventional and confocal fluorescence microscopy, which allows for collaboration with multiple groups to share and implement the obtained knowledge. In parallel to her research activity, she fulfills her didactic commitments in the courses of Medicine and Surgery and Technical Health Professions. LuanaToniolo Luana Toniolo is a university researcher and works as an Assistant Professor in the muscle physiologyandbiophysicslaboratoryoftheDepartmentofBiomedicalSciencesasamemberofthe “Muscle Contractility and Plasticity” research group. The research activity is centered on muscle physiology,particularlythecellularandmolecularaspectsofthediversitybetweenskeletalmuscle fibers.Shespecializesinthepreparationandmanipulationofsingle-skinnedcellsandexvivomuscle preparationsforthestudyofthephysiologicalcharacteristicsofmammalianskeletalmuscle. She isinterestedinvariousproblemsrelatedtomuscletissue, particularlythephysiologicalresponses of skeletal muscle and its adaptations to stimuli such as training, immobilization, denervation or physiological changes such as aging. Alongside her research activity, she has various didactic commitments.HerteachingactivitiesweremainlycarriedoutinthecontextofherdegreeinMedicine andSurgery.Since2011shehasbeenamemberoftheItalianSocietyofPhysiology. vii nutrients Editorial Nutrition, Diet and Healthy Aging EmilianaGiacomello1,*andLuanaToniolo2,* 1 DepartmentofMedicine,SurgeryandHealthSciences,UniversityofTrieste,34149Trieste,Italy 2 LaboratoryofMuscleBiophysics,DepartmentofBiomedicalSciences,UniversityofPadova, 35131Padova,Italy * Correspondence:[email protected](E.G.);[email protected](L.T.) Thecurrentincreaseinlifeexpectancyisconfirmedbydatafromdifferentsources(i.e., TheWorldPopulationProspects2019issuedbytheUnitedNations;https://population.un. org/wpp/(accessedon20December2021)),whichpredictthat,inthenearfuture,individ- ualswhoareover65andover80willbethefastest-growingportionofthepopulation. Althoughtheincreaseinlifespanisapositiveeffectoftheworld’simprovedsanitary, nutritional,andsocioeconomicconditions,itisnotfreeofcomplications. Actually,this improvedlifespanisassociatedwithanintensificationofchronicdiseases,suchascar- diovasculardisease,diabetes,cancer,sarcopenia,anddegenerativedisorders,whichare groupedintowhatarecallednon-communicablediseases. Agingisdeterminedbythefunctionalalterationofcell-andorgan-relatedmechanisms thatcontributetothefunctionaldeclineoftheindividual.Thesealterationsconvergetoa complexconditioncalledfrailty,wheretheindividualexperiencesalossofphysicaland psychologicalabilities,leadingtoastateofincreasedriskforadversehealthoutcomesin severalpathologies. Atpresent,thefrailtyindexisaclinicallyevaluatedmethodthatcanbeusedtoassess thequalityofaging,whichdependsontheindividual’sexpositiontodifferentphysical activities,nutritionalregimens,andothersocioeconomiccharacteristics.Therefore,frailty resultsinamodifiableconditionthatcanbeimprovedwithaffordableadjustmentsin lifestyle,suchasfollowinganutritionalregimenthatmeetstheneedsofagedpeople. TheaimofthisSpecialIssuetitled“NutritionandHealthyAgeing”istoprovide Citation:Giacomello,E.;Toniolo,L. anoverviewontheconnectionbetweennutritionandaging,updateknowledgeonthe Nutrition,DietandHealthyAging. mechanismsthatareresponsibleforaging,andreportonnutritionalstrategiesthatcanbe Nutrients2022,14,190. https:// implementedtoovercomeage-relateddiseases. doi.org/10.3390/nu14010190 ThisSpecialIssuecollects14researcharticlesand4reviewsthatspanfromstudiesin Received:22December2021 thepopulationtobasicresearchonexperimentalmodels.Overall,thecollectiontouches Accepted:29December2021 themessuchasdietarydiversity,calorierestrictionregimens,physicalexercise,antiaging Published:31December2021 agents,socialissues,andstrategiestopromotehealthyaging.Attestingtothewidespread Publisher’sNote:MDPIstaysneutral interestinthecorrelationbetweennutritionandhealthyaging,thecurrentissuereports withregardtojurisdictionalclaimsin dataonthecorrelationbetweendietandhealthyagingfromChina,Italy,Korea,Malaysia, publishedmapsandinstitutionalaffil- Mexico,SaudiArabia,Spain,andtheUnitedStatesofAmerica. iations. Themostmarkedmessagethatemergesfromthiscollectionisthecorrelationbetween thefrailtyindexanddietarydiversity.Studiesfromdifferentcountrieswithverydiverse nutritionalhabitsshowthatagedindividualswithagooddietvarietyscorepresenta betterfrailtyindex[1–10].Evidently,duetothediversegeographicaloriginofthedata,it Copyright: © 2021 by the authors. isdifficulttoinferwhatthebestdiettoavoidortopostponetheoccurrenceoffrailtyis. Licensee MDPI, Basel, Switzerland. Moreover,asdeterminedbythestudyofAvilaandcollaborators[11],othersocioeconomic Thisarticleisanopenaccessarticle factorscanincreasetheriskofmalnutritionandcannegativelyinfluencethehealthstatus distributed under the terms and ofagingpeople. conditionsoftheCreativeCommons Themaintenanceofmentalcapacitiesisoneimportantfactorthatcharacterizeshealthy Attribution(CCBY)license(https:// aging.AsraisedbyworkfromLiuandcollaborators[7]fromandZhang[2]andcollabo- creativecommons.org/licenses/by/ 4.0/). rators,thepsychologicalconditionsofagedpeoplecouldalsobecorrelatedwithdietary Nutrients2022,14,190.https://doi.org/10.3390/nu14010190 1 https://www.mdpi.com/journal/nutrients

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