Nursing Drug Handbook 2021

2040 Pages·2021·11.427 MB·English

by  saunders

IV Compatibilities
The IV compatibility table provides data when 2 or m
a
mtpchprhharaooavytriesfnoeei gcns nemas.o ilToe t idhninbniea ecc lea cojntoumdi oldaoipngntraasec)t mli.aub inrediTel nei htttdgih eesi,irv shsaes oopn(tu ee aliwu.bdngtlh .ieba,ce e nhYl a ei-anursxzgciseeteioer,n lmc ygopi spfrrte eahaedctdepi.ib mprtieialitsinbateiitlensees-,t, Dextrose 5% Sodium Chloride Acyclovir Amikacin Amiodarone Anidulafungin Argatroban Azithromycin Aztreonam Bivalirudin Bumetanide Calcium Gluconate Cefazolin Cefepime Ceftaroline Fosamil Ceftriaxone Ciprofloxacin Clindamycin Daptomycin Dexamethasone Dexmedetomidine Diltiazem Diphenhydramine Dobutamine Dopamine Enalapril Epinephrine Eptifibatide Esmolol Famotidine Fluconazole Furosemide Gentamicin Granisetron Heparin Hydrocortisone Hydromorphone Imipenem Insulin Labetalol Levofloxacin Linezolid Lorazepam Magnesium Mannitol Meropenem Methylprednisolone Metoclopramide Metronidazole Midazolam Morphine Nicardipine Nitroglycerin Nitroprusside Norepinephrine Octreotide Ondansetron Pantoprazole Phenylephrine Piperacillin/Tazobact Potassium Chloride Propofol Sodium Bicarbonate Tigecycline Tobramycin Vancomycin Vasopressin
Acyclovir C C — C N C N N I N N N C N C C N C N C N I C I I N N N N C C N C C C C C C N N I C C C N I C C C N C N N N N N I N N I C C C N C C N
Amikacin C C C — C C N I C C N C C C C C C C C C C C C N N C C N C N C C N C I C C N N C C C C C C N N N N C C C N N C N C I N N C I C C N C N
Amiodarone C C N C — N I N N N N C I N C C C C N N C N N C C N C C C C C C C N I N N I C C N N C I N N C N N C C N C I C N N I C I C N I N C C C
Anidulafungin C C C C N — N N N N N N C C N C C C N C N N N C C N C N N C C C C N C C N C N N C C N N N C C N C C C N N N C N N C C C C N I N C C N
Argatroban C C N N I N — N N N N N N N N N N N N N N C C C C N N C N N N C N N N C N N N N N N N N N N N N N C C N C C C N N N C N N N N N N N C
Azithromycin C C N I N N N — I C N N N N C I I I N N C N N N N N N N N I N I I N N N N I N N I N N N N N N N N N I N N N N N C N N I I N N C I N N
g Aztreonam C C I C N N N N — C C N C N N C C C C C C C C C C C N N N C C C C C C C C C C N N C I C C N C C I N C C N N N N C I N C C C C N C C N
n
cti Bivalirudin C C N C I N N C C — C C C C N C C C N C N C C C C C C C C C C C C N C C C N N C C N C C C N C C C C C N C C C N N N C C C N C N C I N
fli
nistration. able or con BCCaeulfmcaiezuotmalinn Gidlueconate CCC CCC NNC NCC NCI NNC NNN NNN CCC CCC —NN —NC —NC NNN NCC NNI NNC NNC NNN NNN CCC NCC NNN NCI NNN NCC NNC NNN NNC NCC NCI NCC NNI CCC NCC NNC NNI NNN NNC NCC NNN NCC NNC NCC NNN NNC NNI NNI NNC CCI NCC NCC NNN NNN NNC NNN NNC NCI NNN NCC NCI NCC NNC NNN NNC NCI NNN
mi ail Cefepime C C N C N C N N N C N N N — N N N C N N C N N I C N N N N N C C C C C N N N C N N N N N N N C N C I C I N N N N N N N N C I N I I C N
d v
a a Ceftaroline Fosamil C C C C C N N C N N C C N N — N C N N C N C C I C C N N N C C C C C C C C N C I C N C C C N C C C C C N N N C N C C N N C C C N C N C
e via Y-site ble.atibility not CCCleiepfvrtoridiflaiopxoxinanecein CCC CCC NNC NCC NCC NCC NNN NII NCC NCC NNN NCI NNN NNN NNC —NN —NN NII NNC NNI NCC NCC NNC NNC NNC NNN NNN NNN NNN NNC NNI NNI NNC NCC NCI NNI NNN NNN NNN NNI NNN NCC NNC NNI NNN NNN NNI NNC NNC NNC NNC NNN NNN NNN NNC NNN NNN NCI NNN NNN NNC NNC NCI NCC NNC NNI NCC
y compatibly incompation on comp CDDlaeinpxdatoammmeyytchciainnsone CCI CCC NCC CCC NNC NCC NNN NNI CCC NCC NNN NNN NNC NNC NCC NCI NII —NN —NN —NN NCC NNC NNI NNN NNC NNC NNN NNN NNC NNC CCI NNN NCC NCC CCC NCC NCC NNN NNN NNC CCC NCC NNC NNC NNN NNC NNC NCC NNN NCI NCC NNC NNN NNN NNN NNN NCC NNN NNC NCC NCC NCC NCC NNN NNC NNN NNN
allallati Dexmedetomidine C C N C C N N C C N C C C C N C C C N C — C C C C N C N C C C C C C C N C N N C C C C C N N C C C C C N C C C N C N C C C C C N C C N
ccm
ysiysior Diltiazem C C I C N N C N C C C N C N C C C C N N C — N C N N C N C N C I C N C C C C N C N N C N N N I C C C C C C C C N N N N N C N I N C C C
C PhI PhN Inf Diphenhydramine C C C C N N C N C C N N N N C N C N N I C N — N N N N N N C C N N C C N C C N N N C N N N C N C N C C N N N N N C I N C C C N N N N N
Dobutamine C C I N C C C N C C I C N C I N C N N N C C N — C C C N N C C I N C C N C N C C C C C C N N N N N C C C C C C N N I N I C C N C N N C
Dopamine C C I N C C C N C C N N N C C N C N C N C C N C — C C N C C C I N C C C C N I C C C C N N N C N C C C C C C C N C C N C C C N C N N C
Enalapril C C N C N N N N C C N C C N C N N C N N C N N C C — N N C C N N C C C C N N N C N C N C N C C N C N C C C C N N N N N C C C N N N C N
Epinephrine C C N C C C N N N C N C N N N N N N N N C C N C C N — N N N N C N N C C C N N C C N C N N N N N N C C C C C C N N I N N N C I C N N C
Eptifibatide C C N N C N C N N C N N N N N N N N N N N N N N N N N — N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N
Esmolol C C N C C N N N N C N N C N N N N C N N C C N N C C N N — C N I C N C C N N C C N C N C N N N N C N C C C C C N N I N N C C C N C C N
Famotidine C C C N C C N I C C N C C N C C N N N C C N C C C C N N C — C C C C C C C C C C N C C C N N C C N C C C C C C N N N C I C C C N N C N
Fluconazole C C C C C C N N C C N I C C C I N I C C C C C C C N N N N C — I C C C N N I N N N N C N N C N C C C C N C N N N C I N C C C N C C C C
Furosemide C C N C C C C I C C C C N C C N I N N N C I N I I N C N I C I — I C C C C N N I I C C N C C N I N C C I I C C N C C I C C C C N C N I
Gentamicin C C C N C C N I C C N N I C C N C C C N C C N N N C N N C C C I — C I N C N C C C C C C N C N N N C C C N N N N C N N N C I N C N N C
Granisetron C C C C N N N N C N C C C C C C C C N C C N C C C C N N N C C C C — C C C C N N N C C C N N C C C N C N N N N N N N N C N N C N C N N
IV Compatibilities
The IV compatibility table provides data when 2 or m
a
mtpchprhharaooavytriesfnoeei gcns nemas.o ilToe t idhninbniea ecc lea cojntoumdi oldaoipngntraasec)t mli.aub inrediTel nei htttdgih eesi,irv shsaes oopn(tu ee aliwu.bdngtlh .ieba,ce e nhYl a ei-anursxzgciseeteioer,n lmc ygopi spfrrte eahaedctdepi.ib mprtieialitsinbateiitlensees-,t, Dextrose 5% Sodium Chloride Acyclovir Amikacin Amiodarone Anidulafungin Argatroban Azithromycin Aztreonam Bivalirudin Bumetanide Calcium Gluconate Cefazolin Cefepime Ceftaroline Fosamil Ceftriaxone Ciprofloxacin Clindamycin Daptomycin Dexamethasone Dexmedetomidine Diltiazem Diphenhydramine Dobutamine Dopamine Enalapril Epinephrine Eptifibatide Esmolol Famotidine Fluconazole Furosemide Gentamicin Granisetron Heparin Hydrocortisone Hydromorphone Imipenem Insulin Labetalol Levofloxacin Linezolid Lorazepam Magnesium Mannitol Meropenem Methylprednisolone Metoclopramide Metronidazole Midazolam Morphine Nicardipine Nitroglycerin Nitroprusside Norepinephrine Octreotide Ondansetron Pantoprazole Phenylephrine Piperacillin/Tazobact Potassium Chloride Propofol Sodium Bicarbonate Tigecycline Tobramycin Vancomycin Vasopressin
Heparin C C C I I C N N C C N C C C C C I C C C C C C C C C C N C C C C I C — C C N C C I C C C N C C C C C C I C C C N C I N C C C C C I I C
Hydrocortisone C C C C N C C N C C N C N N C N I C N C N C N N C C C N C C N C N C C — N N N N N C C C N N N N N I C C N N C N C N N C N C C N N N N
Hydromorphone C C C C N N N N C C N N I N C N N C N C C C C C C N C N N C N C C C C N — N N C N C C C N N N N C C C C C N C N C I N C N C N N C C N
Imipenem C C C N I C N I C N N N N N N N N N N N N C C N N N N N N C I N N C N N N — C N N C I N N N N N N I N N N N N N C N N N N C I C N N C
Insulin N C N N C N N N C N N N C C C N N N N N N N N C I N N N C C N N C N C N N C — I C N N C N C N N N N C N C N N N N C N N N C C N C C C
Labetalol C C N C C N N N N C N C C N I I N C N N C C N C C C C N C C N I C N C N C N I — N C C C N N N N C C C C C C C N N N N N C C N N C C N
ng Levofloxacin C C I C N C N I N C N N N N C N N C C C C N N C C N C N N N N I C N I N C N I N — C C C N N N N N N C N I I N N N N C N C N C N N C N
fl icti Linezolid C C C C N C N N C N N C C N N C C C N C C N C C C C N N C C N C C C C C C C N C C — C C C C C N C C C C C N N N C N N C C N C C C C C
nistration. able or con LMMoaaragnznneeitpsoailumm —NC —CC NCC CCC NCI NNN NNN NNN CCI CCC NNC NNC NNC NNN CCC NNN NCI NNC NNN NNC NCC NNC NNN NCC NNC NNC NNC NNN NNC NCC NNC NCC NCC NCC NCC NCC NCC NNC NNC NCC NCC CCC —NN —NN —NN NNN NNN NNN NCC NNC NCC NCC NNC NNC NNC NNN NCI NNI NNN NCC CCC CCC NNN NNN NNC NCC NNN
mi ail Meropenem N C I N N C N N N N N C N N N N N N N C N N C N N C N N N N C C C N C N N N C N N C N N N — N C N N C N N N C N I N N N C N N N N C C
d v
a a Methylprednisolone C C C N C C N N C C N I N C C N I C N N C I N N C C N N N C N N N C C N N N N N N C N N N N — N C C C C N N N N I I N C I I C I N N N
e via Y-site ble.atibility not MMMeeidttaorozcnoloildapamrazomleide —CC —CC NCC NNC NNC NCC NNC NNN NCI CCC NNI NCI NCC NCI CCC NNN CCC NCC NNN NCI CCC CCC NCC NNC NCC NNC NNC NNN NNC NCC CCC NCI NNC NCC CCC NNI NCC NNI NNN NCC NNN NCC NCC NNC NNN NNC NCC —NC —NN —CC CCC NCC NNC NNC NNC NNN NNC NNI NNN NCC NNC NNC NNI NNC NNC NNC NNC
y compatibly incompation on comp NNMiioctrraoprghdliiynpceineerin CCC CCC NNC NCC NCC NNC NCC NNI NCC NCC NNC NNC NCC NCI NNC NNC NNN NCC NNN NNC NCC CCC NNC CCC CCC CCC CCC NNN CCC CCC NCC CII NCC NNC CCI NCC CCC NNN NCC CCC NCI CCC CCC NCC NNN NNC NCC NNC NCC CCC —CC —CC —CC CCC CCC NNN NNC NCC NNN NNC NCC NCC NNC NNN NCC NCC NNC
allallati Nitroprusside C C N N I N C N N C N N N N N N N N N N C C N C C C C N C C N C N N C N N N N C I N N C N N N N N C C C C — C N N N N N N C N N N N N
ccm
ysiysior Norepinephrine C C N C C C C N N C N C N N C N C N N N C C N C C N C N C C N C N N C C C N N C N N C N N C N N N C C C C C — N N C N N C C N N N N C
C PhI PhN Inf Octreotide C C N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N N — N I N N N N N N N N N
Ondansetron C C I C N N N C C N N N C N C N N C N C C N C N C N N N N C C C C N C C C C N N N C I C N I I C N N C N N N N N — N N C C N I N N C N
Pantoprazole C C N I I C N N I N N I C N C C I N N I N N I I C N I N I N I C N N I N I N C N N N N N I N I N N I C N C N C I N — N N C N N N N I C
Phenylephrine C C N N C C C N N C N N N N N N N N N N C N N N N N N N N C N I N N N N N N N N C N N N N N N N N N N N N N N N N N — N N N N N N N C
Piperacillin/Tazobactam C C I N I C N I C C C C N N N N N C N C C N C I C C N N N I C C N C C C C N N N N C C C N N C C C N C N N N C N C N N — C N C C I I C
Potassium Chloride C C C C C C N I C C N C N C C N C C N C C C C C C C N N C C C C C N C N N N N C C C C C C C I N N C C C N C C N C C N C — C C C N N N
Propofol C C C I N N N N C N C C C I C C N C N C C N C C C C C N C C C C I N C C C C C C N N C C C N I N N C C N C C C N N N C N C — C N I C N
Sodium Bicarbonate C C C C I I N N C C N C N N C C I C N C C I N N N N I N C C N C N C C C N I C N C C N N N N C N N I C N N N N N I N N C C C — N N C C
Tigecycline C C N C N N N C N N N N N I N C C N N N N N N C C N C N N N C N C N C N N C N N N C N N N N I C N N N N N N N N N N N C C N N — C C N
Tobramycin C C C N C C N I C C N C N I C N C C N N C C N N N N N N C N C C N C I N C N C C N C N C N N N N N C C C N N N N N N N I N I N C — N N
Vancomycin C C C C C C N N C I N C I C N I N N N N C C N N N C N N C C C N N C I N C N C C C C C C N C N N N C C C N N N N C I N I N C C C N — N
Vasopressin — C N N C N C N N N N N N N C N C N N N N C N C C N C N N N C I C N C N N C C N N C N N N C N N C N N N C N C N N C C C N N C N N N —
Saunders
NURSING
DRUG
HANDBOOK
2021
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Saunders
NURSING
DRUG
HANDBOOK
2021
ROBERT J. KIZIOR, BS, RPH KEITH J. HODGSON, RN, BSN, CCRN
Department of Pharmacology Staff Nurse, Intensive Care Unit
Alexian Brothers Medical Center Former Staff Nurse, Emergency
Elk Grove Village, Illinois Department
St. Joseph’s Hospital
Tampa, Florida
Elsevier
3251 Riverport Lane
St. Louis, Missouri 63043
SAUNDERS NURSING DRUG HANDBOOK 2021 ISBN: 978-0-323-75728-7
ISSN: 1098-8661
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Printed in the United States of America
Last digit is the print number: 9 8 7 6 5 4 3 2 1
CONTENTS
DRUGS BY DISORDER xiv
DRUG CLASSIFICATIONS 1C
A–Z DRUG ENTRIES 1
APPENDIXES 1256
A. C alculation of Doses 1256
B. C ontrolled Drugs (United States) 1257
C. Wound Care 1258
D. D rugs of Abuse 1263
E. Equianalgesic Dosing 1270
F. H erbals: Common Natural Medicines 1271
G. L ifespan, Cultural Aspects,
and Pharmacogenomics of Drug Therapy 1278
H. N ormal Laboratory Values 1282
I. Drug Interactions 1284
J. Antidote/Reversal Agents 1289
K. P reventing Medication Errors and Improving
Medication Safety 1294
L. P arenteral Fluid Administration 1298
M. C ommon Terminology Criteria for
Adverse Events (CTCAE) 1301
INDEX 1303
v
AUTHOR BIOGRAPHIES
Robert (Bob) J. Kizior, BS, RPh
Bob graduated from the University of Illinois School of Pharmacy and is licensed to
practice in the state of Illinois. He has worked as a hospital pharmacist for more than
40 years at Alexian Brothers Medical Center in Elk Grove Village, Illinois—a suburb of
Chicago. Bob is the Pharmacy Surgery Coordinator for the Department of Pharmacy,
where he participates in educational programs for pharmacists, nurses, physicians,
and patients. He plays a major role in coordinating pharmacy services in the OR satel-
lite. Bob is a former adjunct faculty member at William Rainey Harper Community
College in Palatine, Illinois.
An avid sports fan, Bob also has eclectic tastes in music that range from classical, big
band, rock ‘n’ roll, and jazz to country and western. Bob spends much of his free time
reviewing the professional literature to stay current on new drug information.
Keith J. Hodgson, RN, BSN, CCRN
Keith was born into a loving family in Chicago, Illinois. His mother, Barbara B. Hodg-
son, was an author and publisher of several medication products, and her work has
been a part of his life since he was a child. By the time he was 4 years old, Keith was
already helping his mother with the drug cards by stacking the draft pages that were
piled up throughout their home.
Because of his mother’s influence, Keith contemplated becoming a nurse in college,
but his mind was fully made up after he shadowed his sister in the Emergency Depart-
ment. Keith received his Associates Degree in Nursing from Hillsborough Community
College and his Bachelor of Science in Nursing from the University of South Florida in
Tampa, Florida. Keith started his career in the Emergency Department and now works
in the Trauma / Neurological/Surgical Intensive Care Unit at St. Joseph’s Hospital in
Tampa, Florida.
Keith’s favorite interests include music, reading, Kentucky basketball, and, if he gets
the chance, watching every minute of the Olympic Games.
vi
REVIEWERS
James Graves, PharmD Travis E. Sonnett, PharmD
Clinical Pharmacist Inpatient Pharmacy Supervisor
University of Missouri Hospital Mann-Grandstaff VA Medical Center;
Columbia, Missouri Residency Program Director
Washington State University College of Pharmacy
Spokane, Washington
vii