NSF/ANSI 49 NSF/ANSI 49

96 Pages·2011·3.98 MB·English

NNSSFF//AANNSSII 4499 -- 22001100
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Copyright © 2011 Micro-Clean, Inc.
All Rights Reserved
Copyright © NSF 2010
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Micro-Clean, Inc. does not represent, endorse, or
recommend any BSC or filtration device
manufacturer, or type of device over another. Any
pictures, materials or descriptions presented here are
for educational purposes only.
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• Understand the latest NSF/ANSI Std 49
changes on how they impact current
BSC installations.
– Many older BSCs may not meet the current
expectations of NSF
– Customers should routinely evaluate their
safety and equipment processes as part of
safety committees with key departments
represented
BBSSCC TTyyppeess AA11 // AA22
• have HEPA/ULPA filtered downflow air that is a portion of
the mixed downflow and inflow air from a common plenum
(i.e., a plenum from which a portion of the air is exhausted
from the cabinet and the remainder supplied to the work
area);
• may exhaust HEPA/ULPA filtered air back into the laboratory
or to the environment through an external exhaust system
connected to the cabinet with a canopy connection; and
• Type A1 cabinets are not suitable for work with volatile toxic
chemicals and tracer amount of volatile radionuclides
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BBSSCC TTyyppee BB11
• have HEPA/ULPA filtered downflow air composed
largely of uncontaminated recirculated inflow air;
• exhaust most of the contaminated downflow air to an
external exhaust system through a dedicated duct
connected to cabinet with a direct connection and
exhausted to the atmosphere after passing through a
HEPA/ULPA filter; and
BBSSCC TTyyppee BB22
• have HEPA/ULPA filtered downflow air drawn from the
laboratory or the outside air (i.e., downflow air is not
recirculated from the cabinet exhaust air);
• exhaust all inflow and downflow air to the atmosphere
through an external exhaust system connected to cabinet
with a direct connection after filtration through a
HEPA/ULPA filter without recirculation in the cabinet or
return to the laboratory; and
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• Canopy connection
• Direct connection
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• Canopy connection – required for
externally vented A1 or A2 BSC (5.2)
• Direct connection – required for
externally vented B1 or B2 BSC (5.3)
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• All biologically contaminated ducts and
plenums in Types A1, A2, B1, and A2
cabinets shall be maintained under
negative pressure or enclosed within a
negative pressure zone. (5.4)
– B2 directly exhausted (nonrecirculated)
negative pressure zone was dropped
AA11 // AA22 EExxhhaauusstt AAllaarrmmss
• Any Type A1 or A2 cabinet when
canopy connected shall have an audible
and visual alarm to indicate notifying the
user of a potential loss in canopy
containment (5.23.4)
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Copyright © NSF 2010
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• Conforms to requirements of UL 61010-1
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• The cabinet shall be tested by a National
Recognized Testing Laboratory (NRTL) for
compliance to the requirements of the current
edition of any national standard that is based
on IEC 61010-1. Compliance is demonstrated
by cabinet listing, i.e. UL, CSA, or IECEE CB
Scheme certificate.
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• The manufacturer shall determine the aerosol
introduction point that provides the most uniform
distribution (reference IEST-RP-CC-03422). The
location of the aerosol introduction point shall be
clearly described or indicated in a manner readily
available to the certifier. The location should be
described either on the cabinet data plate or with the
electrical schematic if the schematic is affixed to the
cabinet. (NSF 49 - 2009, A.2.3.1)
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AAnnnneexx GG ppaarrttss ttoo AAnnnneexx EE
• “BSC Selection, Installation, Life Span and
Decommissioning” section was moved from
Annex G (Decontamination) to Annex E,
now this title renames Annex E with this
new information.
– Formerly “Recommendations for Installation”
MMoovveedd ffrroomm AAnnnneexx GG ttoo EE
• E.1.Biosafety Consultation Prior to BSC Purchase
• Risk Assessment Procedure
• Selection of a BSC cabinet
• Prior to the Purchase [“Location” section from old Annex E
ended up in here]
• Inspection
• Moving a Permanently Installed Biosafety Cabinet
• Lifespan of BSCs
• E.8. Decommissioning process
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Copyright © NSF 2010
EE..22..88 RRiisskk
AAsssseessssmmeenntt
• Risk Management
Assessment Table was
reworked
• Biosafety Cabinet Selection
• Configuration drawings
added
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• What needs to be protected?
• What are all of the different types of work to be done in
the cabinet?
• What types and quantities of chemical vapors will be
generated in the BSC?
• If the unit requires an exhaust system, is there an
appropriate location for the cabinet and its ductwork?
• NEW QUESTION: If the volume of air moved by the BSC
exhaust system is reduced, or eliminated, due to a
malfunction, what is its effect on BSC performance, and
what is preferred by the user?
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““NNoott aacccceeppttaabbllee”” hhaarrdd dduucctteedd AA’’ss
• Question #4
• E.3.1.4 (formerly) G.3.1.5. If the unit requires an exhaust
system, is there an appropriate location for the
cabinet and its ductwork?
• 2ndpara: When connected to a hard-ducted exhaust system, however,
the location of the cabinet becomes dependent on the location of the
exhaust system. The exhaust duct must be placed so it can penetrate
ceilings and floors without disturbing other ventilation or plumbing
systems. The exhaust system must also be designed to minimize
excessive lengths and elbows. The exhaust system configurations of
Type A and Type B BSCs are shown in figures E3 and E6,
respectively. Hard ducting Type A cabinets is not acceptable and
shall only be exhausted through a properly designed and fitted
exhaust canopy.
EE..33..33..22 EElleeccttrriiccaall OOuuttlleettss
• Work area outlet are limited in their
amperage rating due to other components
on the same power cord, blowers, lights, etc.
• Recommendation to add an external voltage
regulator when wall outlet line voltage
variations affect cabinet airflows.
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