Non‐Alzheimer’s and Atypical Dementia Non‐Alzheimer’s and Atypical Dementia Edited by Michael D. Geschwind, MD phD Memory and Aging Center Department of Neurology University of California, San Francisco San Francisco, CA, USA Caroline Racine Belkoura, phD Department of Neurological Surgery University of California, San Francisco San Francisco, CA, USA This edition first published 2016 © 2016 by John Wiley & Sons, Ltd Registered Office John Wiley & Sons, Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK Editorial Offices 9600 Garsington Road, Oxford, OX4 2DQ, UK The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK 111 River Street, Hoboken, NJ 07030‐5774, USA For details of our global editorial offices, for customer services and for information about how to apply for permission to reuse the copyright material in this book please see our website at www.wiley.com/wiley‐blackwell The right of the author to be identified as the author of this work has been asserted in accordance with the UK Copyright, Designs and Patents Act 1988. All rights reserved. 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No warranty may be created or extended by any promotional statements for this work. Neither the publisher nor the author shall be liable for any damages arising herefrom. Library of Congress Cataloging‐in‐Publication Data Non-Alzheimer’s and atypical dementia / edited by Michael D. Geschwind, Caroline Racine Belkoura. p. ; cm. Includes bibliographical references and index. ISBN 978-1-4443-3624-5 (cloth) I. Geschwind, Michael D., editor. II. Belkoura, Caroline Racine, editor. [DNLM: 1. Dementia. 2. Alzheimer Disease. 3. Neurobehavioral Manifestations. WM 220] RC521 616.8′3–dc23 2015036764 A catalogue record for this book is available from the British Library. Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books. Set in 9.5/12pt Minion by SPi Global, Pondicherry, India 1 2016 Contents Notes on contributors, vi 9 Prion diseases and rapidly progressive dementias, 103 Leonel T. Takada and Michael D. Geschwind 1 Introduction, 1 Michael D. Geschwind and Caroline Racine Belkoura 10 Autoimmune dementias, 123 Andrew McKeon and Sean J. Pittock 2 The multidisciplinary evaluation of the atypical dementia patient, 6 11 Toxic and metabolic dementias, 134 Michael D. Geschwind and Caroline Racine Belkoura Michelle Mattingly, Katie Osborn and Leon Prockop 3 Atypical Alzheimer’s disease, 17 12 Leukoencephalopathies/leukodystrophies, 150 Sharon J. Sha and Gil D. Rabinovici Gregory M. Pastores and Swati A. Sathe 4 Vascular cognitive impairment: Diagnosis 13 Infectious causes of dementia, 170 and treatment, 30 Cheryl A. Jay, Emily L. Ho and John Halperin Helena C. Chui and Liliana Ramirez-Gomez 14 Rheumatologic and other autoimmune dementias, 186 5 Frontotemporal dementia, 49 Laura J. Julian and Christopher M. Filley David C. Perry and Howard J. Rosen 15 Comprehensive management of the patient with 6 Lewy body dementias (DLB/PDD), 64 an atypical dementia, 202 Carol F. Lippa and Katherine L. Possin Jennifer Merrilees, Cynthia Barton, Amy Kuo and Robin Ketelle 7 Corticobasal degeneration and progressive supranuclear palsy, 77 Index, 215 Suzee E. Lee and Bruce L. Miller 8 Repeat expansion diseases and dementia, 90 Praveen Dayalu, Roger L. Albin and Henry Paulson v Notes on contributors Roger L. Albin, MD Liliana Ramirez-Gomez, MD Anne B. Young Collegiate Professor of Neurology Adjunct Assistant Professor of Clinical Neurology University of Michigan Department of Neurology and Keck School of Medicine Chief, Neuroscience Research, VAAAHS GRECC University of Southern California Ann Arbor, MI, USA Los Angeles, CA, USA Cynthia Barton, RN MSN John Halperin, MD FAAN FACP Nurse Practitioner Medical Director Health Sciences Assistant Clinical Professor Atlantic Neuroscience Institute Memory and Aging Center Summit, NJ, USA Department of Neurology and University of California, San Francisco Professor of Neurology & Medicine San Francisco, CA, USA Sidney Kimmel Medical College of Thomas Jefferson University Philadelphia, PA, USA and Caroline Racine Belkoura, PhD Chair, Department of Neurosciences Assistant Professor Overlook Medical Center Clinical Neuropsychologist Summit, NJ, USA Department of Neurological Surgery University of California, San Francisco Emily L. Ho, MD PhD San Francisco, CA, USA Clinical Instructor in Neurology University of Washington Helena C. Chui, MD and McCarron Professor and Chair Neurohospitalist Department of Neurology Swedish Neuroscience Institute Keck School of Medicine Seattle, WA, USA University of Southern California Los Angeles, CA, USA Cheryl A. Jay, MD Health Sciences Clinical Professor of Neurology Praveen Dayalu, MD University of California, San Francisco and Assistant Professor Neurology Service Department of Neurology San Francisco General Hospital (SFGH) University of Michigan San Francisco, CA, USA Ann Arbor, MI, USA Laura J. Julian, PhD Christopher M. Filley, MD Assistant Professor of Medicine Professor of Neurology and Psychiatry University of California, San Francisco Director, Behavioral Neurology Section San Francisco, CA, USA University of Colorado School of Medicine and Robin Ketelle, RN MS Neurology Service Chief Clinical Nurse Specialist Denver VA Medical Center Health Sciences Assistant Clinical Professor Denver, CO, USA Memory and Aging Center Department of Neurology Michael D. Geschwind, MD PhD University of California, San Francisco Professor of Neurology San Francisco, CA, USA Michael J. Homer Chair in Neurology Memory and Aging Center Amy Kuo, RN MS GNP‐BC Department of Neurology Nurse Practitioner University of California, San Francisco On Lok Lifeways San Francisco, CA, USA San Francisco, CA, USA vi Notes on contributors vii Suzee E. Lee, MD David C. Perry, MD Assistant Professor of Neurology Assistant Professor Memory and Aging Center Memory and Aging Center Department of Neurology Department of Neurology University of California, San Francisco University of California, San Francisco San Francisco, CA, USA San Francisco, CA, USA Carol F. Lippa, MD Sean J. Pittock, MD Professor and Interim Chair Professor of Neurology Department of Neurology Director, Neuroimmunology Laboratory Director, Memory and Cognitive Disorders Program Director, Center for MS and Autoimmune Neurology Drexel Neurosciences Institute Mayo Clinic Drexel University College of Medicine Rochester, MN, USA Philadelphia, PA, USA Katherine L. Possin, PhD Michelle Mattingly, PhD ABPP Assistant Professor of Neuropsychology Assistant Professor Memory and Aging Center Departments of Psychiatry and Behavioral Neurosciences and Neurology Department of Neurology University of South Florida College of Medicine University of California, San Francisco Tampa, FL, USA San Francisco, CA, USA Andrew McKeon, MD Leon Prockop, MD Associate Professor of Neurology, and Laboratory Medicine and Pathology Department of Neurology Neurologist, Department of Neurology University of South Florida Co‐Director, Neuroimmunology Laboratory Tampa, FL, USA Mayo Clinic Rochester, MN, USA Gil D. Rabinovici, MD Associate Professor of Neurology Jennifer Merrilees, RN PhD Memory and Aging Center Clinical Nurse Specialist Department of Neurology Health Sciences Associate Clinical Professor University of California, San Francisco Memory and Aging Center San Francisco, CA, USA Department of Neurology University of California, San Francisco Howard J. Rosen, MD San Francisco, CA, USA Professor of Neurology Bruce L. Miller, MD Memory and Aging Center Department of Neurology A.W and Mary Clausen Distinguished Professor of Neurology University of California, San Francisco Memory and Aging Center San Francisco, CA, USA Department of Neurology University of California, San Francisco Swati A. Sathe, MD MS San Francisco, CA, USA Associate Professor Katie Osborn, MA Department of Neurology Neurological Institute of New Jersey Predoctoral Intern Rutgers, The State University of New Jersey Department of Psychiatry New Jersey Medical School Geisel School of Medicine at Dartmouth Newark, NJ, USA Hanover, NH, USA Gregory M. Pastores, MD Sharon J. Sha, MD MS Consultant Clinical Assistant Professor National Center for Inherited Metabolic Diseases Neurology and Neurological Sciences Department of Medicine Stanford Center for Memory Disorders Mater Misericordiae University Hospital Stanford, CA, USA Dublin, Ireland and and Memory and Aging Center Visiting Professor Department of Neurology Department of Medicine University of California, San Francisco Yale University School of Medicine San Francisco, CA, USA New Haven, CT, USA Leonel T. Takada, MD PhD Henry Paulson, MD PhD Neurologist at Hospital das Clinicas Lucile Gross Professor of Neurology Department of Neurology University of Michigan University of Sao Paulo Medical School Ann Arbor, MI, USA Sao Paulo, Brazil
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