Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics PDF
Preview Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics
Gorachand Dutta Editor Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics Gorachand Dutta Editor Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics Editor GorachandDutta SchoolofMedicalScienceand Technology IndianInstituteofTechnologyKharagpur Kharagpur,WestBengal,India ISBN978-981-19-7129-7 ISBN978-981-19-7130-3 (eBook) https://doi.org/10.1007/978-981-19-7130-3 #TheEditor(s)(ifapplicable)andTheAuthor(s),underexclusivelicensetoSpringerNatureSingapore PteLtd.2023 Thisworkissubjecttocopyright.AllrightsaresolelyandexclusivelylicensedbythePublisher,whether thewholeorpartofthematerialisconcerned,specificallytherightsoftranslation,reprinting,reuseof illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similarordissimilarmethodologynowknownorhereafterdeveloped. Theuseofgeneraldescriptivenames,registerednames,trademarks,servicemarks,etc.inthispublication doesnotimply,evenintheabsenceofaspecificstatement,thatsuchnamesareexemptfromtherelevant protectivelawsandregulationsandthereforefreeforgeneraluse. The publisher, the authors, and the editorsare safeto assume that the adviceand informationin this bookarebelievedtobetrueandaccurateatthedateofpublication.Neitherthepublishernortheauthorsor theeditorsgiveawarranty,expressedorimplied,withrespecttothematerialcontainedhereinorforany errorsoromissionsthatmayhavebeenmade.Thepublisherremainsneutralwithregardtojurisdictional claimsinpublishedmapsandinstitutionalaffiliations. ThisSpringerimprintispublishedbytheregisteredcompanySpringerNatureSingaporePteLtd. The registered company address is: 152 Beach Road, #21-01/04 Gateway East, Singapore 189721, Singapore Preface The modern era makes our life more complex. This emergence of dynamic com- plexityeveninhealthcaresectorsmakestheworldtocomeupwithasmartsolution. Theevolutionofpoint-of-caretestingprovidesmedicaldiagnosiswithinandoutside thelaboratory.Suchbench-to-bedsidediagnosisadvancespatientmanagementtoa greatextent.Tocatertotheneeds,asignificantamountoffocushasbeendedicated to developing an inexpensive, accurate, sensitive point-of-care device at an afford- ablepricetoreachthecommonpeople. Rapid detection and point-of-care (POC) diagnostics have become very crucial especiallyafterthelife-threateningcoronaviruspandemic.Thepandemichasproved thatdespitetremendousadvancesinmedicalsciencesandtechnology,sorelyweare lagging in healthcare research. Detection schemes can be realized with an electro- chemical platform, thanks to its promising advantages like low-to-moderate cost, high sensitivity, and selectivity with a lower limit of detection (LOD), rapid response,andeasyintegrationwithmicrofluidicsystems.Avarietyofsignalampli- ficationmethodsbasedonelectrochemical-chemical-chemical(ECC)redoxcycling and rolling circle amplification (RCA) have been explored. Integration of these systems opens a new horizon to fabricate miniaturized devices, disposability, need forlesssamplevolume,multiplex,andPOCsensingability. Our motto is to fabricate a label-free, wash-free, and portable electrochemical biosensorforpoint-of-careapplicationandearlydetectionofdisease.Itwillbeinthe form of a handheld or bench-top instrument which will accept a sample with very little or no pre-preparation and can provide a comprehensible result in seconds to hoursforeasyinterpretation.Next-GenerationNanobiosensorDevicesforPoint-of- CareDiagnosticswaspreparedforbeginningandexperiencedauthorstoexplorethe challengesforthedevelopmentofnext-generationpoint-of-caretestplatformusing nanobiotechnology. Inthisbook,weaddressthesechallengesforthedevelopmentofapoint-of-care test platform. The book also describes printed chip-based assays (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive, biomarkers detection in real samples. The main challenges of point-of-care testing require implementing complex analytical methodsintolow-costtechnologies.Thisisparticularlytrueforcountrieswithless developedhealthcare infrastructure.Wash-free, Lab-on-a-Chip,andLab-on-a-PCB techniques are very simple and innovative for point-of-care device development. v vi Preface Theredoxcyclingtechnologycandetectseveralinterestingtargetsatthesametime onaprintedchip.Theareasareinherentlycross-disciplinary,combiningexpertisein biosensing,electrochemistry,electronicsandelectricalengineering,healthcare,and manufacturing. Other focus audience includes physical and chemical science scientistswhoareinvolvedinthedevelopmentofananalytical devicefortheeasy andearlydetectionofchronicdiseases.Furthermore,otherthanresearchpurposes, this book can potentially also be helpful for nanobiotechnology and biomedical engineeringteachersandstudents.Besides,chaptersareorganizedinsuchawaythat the reader can easily understand the emphasis of each chapter’s focus to select appropriate biosensors of interest. The title covers a very vast audience from basic science to engineering and technology experts and learners. This could eventually work as a textbook for engineering and biomedical students or science master’s programs and for researchers. This title also serves the common public interest by presenting new methods for data evaluation and medical diagnosis to improve the qualityoflifeingeneral,withabetterintegrationintosociety. Kharagpur,India GorachandDutta Contents RecentDevelopmentinDetectionSystemsforHumanViralPathogens fromClinicalSampleswithSpecialReferencetoBiosensors. . . . . . . . . . 1 KamalShokeen,PurvitaChowdhury,andSachinKumar NanobiosensorsforCOVID-19. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Karthik.N.andAvijitKumarDas ElectrochemicalDetectionofCancerFingerprint:ASystematic ReviewonRecentProgressinExtracellularVesicleResearch fromLabtoMarket. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47 BrateenDatta,NirmitaDutta,AmlanAshish,MuktiMandal,JaiShukla, RaghavvSuresh,PriyankaChoudhury,KoelChaudhury, andGorachandDutta Nano-biosensorsforDiagnosingInfectiousandLifestyle-Related DiseaseofHuman:AnUpdate. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 SomritaPadma,PrithaChakraborty,andSuprabhatMukherjee DesignandAnalysisofOne-DimensionalPhotonicCrystalBiosensor DeviceforIdentificationofCancerousCells. . . . . . . . . . . . . . . . . . . . . . 105 AbinashPandaandPuspaDeviPukhrambam SmartNanobiosensingforCOVID-19Diagnosis. . . . . . . . . . . . . . . . . . . 123 SayakRoyChowdhuryandMonidipaGhosh MachineLearning-EnabledBiosensorsinClinicalDecisionMaking. . . . 163 SrishtiVerma,RajendraP.Shukla,andGorachandDutta RecentProgressontheDevelopmentofChemosensors. . . . . . . . . . . . . . 195 TiasaDas,SanskarJain,andAvijitKumarDas vviiii viii Contents MedicalDeviceandEquipmentSectorinIndia:Towards SophisticatedDigitalHealthcareSystems—AnOverview. . . . . . . . . . . . 211 P.K.Paul ApplicationofRadiopharmaceuticalsinDiagnosticsandTherapy. . . . . 227 PriyaSarkar,ShivaniKhatana,BimalenduMukherjee,JaiShukla, BiswajitDas,andGorachandDutta About the Editor Gorachand Dutta PhD is an Assistant Professor with theSchool ofMedicalScience and Technology,Indian Institute of Technology Kharagpur. His research interestsincludethedesignandcharacterizationofpor- table biosensors, biodevices, and sensor interfaces for miniaturized systems and biomedical applications for point-of-caretesting.HereceivedhisPh.D.inBiosensor and Electrochemistry from Pusan National University, South Korea, where he developed different classes of electrochemicalsensors.Hecompletedhispostdoctoral fellowshipsintheDepartmentofMechanicalEngineer- ing, Michigan State University, USA, and the Depart- ment of Electronic and Electrical Engineering at the University of Bath, UK. He has expertise on label-free multichannel electrochemical biosensors, electronically addressablebiosensorarrays,aptamer-andDNA-based sensorsandsurfacebio-functionalization. He is recipient of many prestigious awards and fellowships, such as the prestigious Pusan National University Research Fellowship, BK-21 Fellowship SouthKorea. iixx Recent Development in Detection Systems for Human Viral Pathogens from Clinical Samples with Special Reference to Biosensors Kamal Shokeen, Purvita Chowdhury, and Sachin Kumar Abstract Overthelastfewdecades,theemergenceandre-emergenceofvariouspathogenic viruses have significantly impacted human health. The continuous rise in cases withincreasingmortalityrateshasdriventhechaseforeffectivetreatmentoptions andearlydiagnosistocombatthisglobalhealthissue.Currently,usedlaboratory techniquesforvirusdetectionrequirecomplexequipment,trainedpersonnel,and, mostimportantly,aretime-consuming.Intimesofoutbreaksandepidemicslike COVID-19 and Ebola, easy-to-use and point-of-care tests, especially for devel- opingandunderdevelopedcountries,areindispensable. Thischapterexplicitlydiscussestheavailabilityofthedetectionmethodsfor varioushumanviralpathogenswiththeirshortcomingsandrecentadvancements inbiosensors.Withtheongoingimprovementinbiosensors,theseholdimportant avenues for rapid, sensitive, and scalable devices for viral diagnostic purposes. Theeffectivenessofpreviouslyknownandcurrentapproaches/devices/methods thatutilizedifferentprinciplesfordetectionhasalsobeenreviewedhere,withthe listingofalltheavailabletestsforvarioushumanpathogens. Keywords Virus·Biosensor·Viralprotein·Viralnucleicacid·Diagnosis ✉ K.Shokeen·P.Chowdhury·S.Kumar( ) DepartmentofBiosciencesandBioengineering,IndianInstituteofTechnologyGuwahati, Guwahati,India e-mail:[email protected] #TheAuthor(s),underexclusivelicensetoSpringerNatureSingaporePte 1 Ltd.2023 G.Dutta(ed.),Next-GenerationNanobiosensorDevicesforPoint-Of-Care Diagnostics,https://doi.org/10.1007/978-981-19-7130-3_1
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