|13.10.21-14:34 |13.10.21-14:34 |13.10.21-14:34 Neurosurgical Diseases AnEvidence-BasedApproachtoGuidePractice LeonT.Lai,MBBS,PhD,FRACS AssociateProfessorofNeurologicalSurgery DepartmentofSurgery MonashUniversity; HeadofCerebrovascularSurgeryandSkullBaseNeurosurgeon DepartmentofNeurosurgery MonashHealth Melbourne,Australia CristianGragnaniello,MD,PhD AssistantProfessorofNeurologicalSurgery DepartmentofNeurologicalSurgery UniversityofTexasHealthScienceCenteratSanAntonio SanAntonio,Texas,USA 149illustrations Thieme NewYork(cid:129)Stuttgart(cid:129)Delhi(cid:129)RiodeJaneiro |13.10.21-14:34 Library of Congress Cataloging-in-Publication Data is available Importantnote:Medicineisanever-changingscienceundergoing withthepublisher. continual development. Research and clinical experience are continuallyexpandingourknowledge,inparticularourknowledge of proper treatment and drug therapy. 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LeonT.Lai,MBBS,PhD,FRACS CristianGragnaniello,MD,PhD |13.10.21-14:34 |13.10.21-14:34 Contents Foreword ................................................................................. xv Preface ................................................................................... xvi Acknowledgments ....................................................................... xvii Contributors ............................................................................. xviii 1. NaturalHistoryandManagementOptionsofRecurrentGlioblastoma..................... 1 BenjaminH.M.HunnandKatharineJ.Drummond 1.1 Introduction.............................. 1 1.5 TreatmentOptionsforRecurrent Glioblastoma............................. 4 1.2 SelectedPapersontheNaturalHistoryof RecurrentGlioblastoma ................... 1 1.5.1 RepeatSurgery............................ 5 1.5.2 FurtherRadiotherapy....................... 6 1.3 TheNaturalHistoryofRecurrent 1.5.3 FurtherChemotherapy ..................... 6 Glioblastoma ............................. 2 1.6 Authors’Recommendations............... 6 1.4 SelectedPapersontheTreatmentOutcomes ofRecurrentGlioblastoma................. 4 2. NaturalHistoryandManagementOptionsofUnrupturedBrainArteriovenous Malformation..................................................................................... 8 MichaelKerinMorgan 2.1 Introduction.............................. 8 2.4 TreatmentOptionsforUnrupturedBrain AVM..................................... 12 2.2 SelectedPapersontheNaturalHistoryof UnrupturedbAVM ........................ 8 2.4.1 Embolization.............................. 14 2.4.2 Radiosurgery.............................. 14 2.2.1 ComparingFutureRiskofICHforUnruptured 2.4.3 SurgerywithorwithoutPlannedPreoperative bAVM..................................... 9 Embolization.............................. 15 2.2.2 FactorsthatImpactontheRiskofFirstICH..... 10 2.4.4 ResultsofSurgery.......................... 19 2.2.3 TheExpectedOutcomefrombAVMICH ....... 11 2.4.5 CombinedTreatment....................... 20 2.2.4 UnderstandingtheCauseforICHAssociated 2.4.6 ConclusionRegardingTreatment............. 20 withbAVM................................ 11 2.3 SelectedPapersontheTreatmentOptions forUnrupturedBrainAVM................. 12 3. NaturalHistoryandSurgicalManagementofSpontaneousIntracerebralHemorrhage.. 25 JonathanRychenandDavidBervini 3.1 Introduction.............................. 25 3.4 NaturalHistoryofSpontaneous SupratentorialICH........................ 28 3.2 SelectedPapersontheNaturalHistoryof SpontaneousICHs......................... 25 3.5 NaturalHistoryofSpontaneous InfratentorialICH......................... 29 3.3 NaturalHistoryofSpontaneous ICHs...................................... 26 3.6 SelectedPapersonSurgicalManagementof SpontaneousICHs ........................ 29 vii |13.10.21-14:34 Contents 3.7 SurgicalManagementOptionsfor 3.11 MedicalManagementofSpontaneousICH.. 31 SpontaneousICHs ........................ 29 3.12 Authors’Recommendations................ 32 3.8 SurgicalManagementofSpontaneous SupratentorialICH........................ 30 3.12.1 MedicalManagementofSpontaneous ICH....................................... 32 3.9 SurgicalManagementofSpontaneous 3.12.2 ManagementofSupratentorialHemorrhage.... 32 InfratentorialICH......................... 31 3.12.3 ManagementofInfratentorialHemorrhage..... 32 3.12.4 ManagementofIntraventricularHemorrhage... 32 3.10 SurgicalManagementforSpontaneousICH AssociatedwithIntraventricular Hemorrhage ............................. 31 4. NaturalHistoryandManagementOptionsofPinealCyst .................................... 35 MichaelJ.MulcahyandBehzadEftekhar 4.1 Introduction.............................. 35 4.4 SelectedPapersontheTreatmentOptions forPinealCyst ............................ 37 4.2 SelectedPapersontheNaturalHistoryof PinealCyst............................... 36 4.5 TreatmentOptionsforPinealCysts......... 37 4.3 NaturalHistory........................... 36 4.6 Authors’Recommendations................ 37 5. NaturalHistoryandManagementOptionsofColloidCysts.................................. 40 AntheaH.O’Neill,CristianGragnaniello,andLeonT.Lai 5.1 Introduction.............................. 40 5.5 SelectedPapersontheTreatmentOutcomes ofColloidCysts............................ 42 5.2 SelectedPapersontheNaturalHistoryof ColloidCysts ............................. 40 5.6 TreatmentOptions........................ 42 5.3 NaturalHistoryofColloidCysts............ 40 5.7 Authors’Recommendations................ 43 5.4 PredictingtheRiskofSuddenDeath....... 42 6. NaturalHistoryandManagementOptionsofVestibularSchwannomas.................... 46 JordanJones,AndrewH.Kaye,andAndrewMorokoff 6.1 Introduction.............................. 46 6.5 Treatment ................................ 48 6.2 SelectedPapersonNaturalHistory ........ 46 6.5.1 Microsurgery .............................. 48 6.5.2 StereotacticRadiosurgery.................... 49 6.3 NaturalHistory........................... 47 6.5.3 MicrosurgeryandStereotacticRadiosurgery.... 50 6.5.4 NeurofibromatosisType2.................... 50 6.3.1 RateofGrowth ............................ 47 6.3.2 RiskFactorsforGrowth..................... 47 6.6 Authors’Recommendations................ 50 6.3.3 GrowthinNeurofibromatosisType2Vestibular Schwannomas............................. 48 6.4 SelectedPapersonTreatment............. 48 7. NaturalHistoryandManagementOptionsofAcromegaly................................... 53 MendelCastle-KirszbaumandTonyGoldschlager 7.1 Introduction.............................. 53 7.2 Pathology ................................ 53 viii