Neuropathology of Drug Addictions and Substance Misuse. Volume 3: General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions

1017 Pages·2016·70.52 MB·English

by  Victor R. Preedy

Neuropathology of Drug
Addictions and Substance
Misuse
Volume 3: General Processes and Mechanisms,
Prescription Medications, Caffeine and
Areca, Polydrug Misuse, Emerging
Addictions and Non-Drug Addictions
Edited by
Victor R. Preedy
King’s College London, London, UK
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List of Contributors
Ghulam Abbas H.E.J. Research Institute of Chemistry, Anzari Atik The Ritchie Centre, Hudson Institute of
International Center for Chemical and Biological Medical Research, Clayton, VIC, Australia
Sciences, University of Karachi, Karachi, Pakistan
Anna Rita Atti Bologna University, Bologna, Italy
Piotr Adamowicz Institute of Forensic Research, Krakow,
Alison L. Baird Department of Psychiatry, Medical
Poland
Sciences Division, University of Oxford, Oxford,
Ana Adan Department of Psychiatry and Clinical United Kingdom
Psychobiology, University of Barcelona, Barcelona,
Michela Balconi Research Unit in Affective and Social
Spain; Institute for Brain, Cognition and Behaviour
Neuroscience, Department of Psychology, Catholic
(IR3C), Barcelona, Spain
University of Milan, Milan, Italy
Nirit Agay Max Wertheimer Minerva Center for Cognitive
Anna Lukačišinová Ballóková Department of Geriatrics
Studies, Faculty of Industrial Engineering and
and Gerontology, 1st Faculty of Medicine, Charles
Management, Technion – Israel Institute of Technology,
University in Prague, Prague, Czech Republic
Haifa, Israel
M.T. Bascarán Centro de Investigación Biomédica en
S. Al-Halabí Centro de Investigación Biomédica en Red de
Red de Salud Mental (CIBERSAM), Department of
Salud Mental (CIBERSAM), Department of Psychiatry,
Psychiatry, University of Oviedo, Oviedo, Spain
University of Oviedo, Oviedo, Spain
Gemma Battagliese Department of Clinical Medicine,
Hatice Altun Department of Child and Adolescent
Sapienza-University of Rome, Viale dell’ Università,
Psychiatry, School of Medicine, Kahramanmaras
Rome, Italy
Sutcuımam University, Kahramanmaras, Turkey
Irina Benaiges Department of Psychiatry and Clinical
Maryam Amini Department of Chemistry, Isfahan
Psychobiology, University of Barcelona, Barcelona,
University of Technology, Isfahan, Iran
Spain
Monica L. Andersen Department of Psychobiology,
Dessa Bergen-Cico Department of Public Health, Addiction
Universidade Federal de São Paulo (UNIFESP), Sao
Studies, Syracuse University, Syracuse, NY, USA
Paulo, SP, Brazil
Cecilie Schou Andreassen Department of Psychosocial Wade H. Berrettini Department of Psychiatry, Center for
Science, University of Bergen, Bergen, Norway; Centre Neurobiology and Behavior, University of Pennsylvania
of Competence, Bergen Clinics Foundation, Bergen, School of Medicine, Philadelphia, PA, USA
Norway Laís F. Berro Department of Psychobiology, Universidade
James C. Anthony College of Human Medicine, Michigan Federal de São Paulo (UNIFESP), Sao Paulo, SP,
State University, East Lansing, MI, USA Brazil
Yalda Hosseinzadeh Ardakani Biopharmaceutics Elisabetta Bertol Department of Health Sciences,
and Pharmacokinetic Division, Department of Division of Forensic Toxicology, University of Florence,
Pharmaceutics, Faculty of Pharmacy, Tehran University Florence, Italy
of Medical Sciences, Tehran, Iran Jin-Song Bian Department of Pharmacology, Yong
Mariarosaria Aromatario Legal Medicine Section, Loo Lin School of Medicine, National University of
SAIMLAL Department, SAPIENZA University of Singapore, Singapore
Rome, Viale Regina Elena, Rome, Italy M.T. Bobes-Bascarán Centro de Investigación Biomédica
Priti Arun Department of Psychiatry, Government Medical en Red de Salud Mental (CIBERSAM), University of
College and Hospital, Chandigarh, India Valencia, Valencia, Spain
xxv
xxvi List of Contributors
J. Bobes Centro de Investigación Biomédica en Red de Verònica Casadó-Anguera Centro de Investigación
Salud Mental (CIBERSAM), Department of Psychiatry, Biomédica en Red sobre Enfermedades Neurode-
University of Oviedo, Oviedo, Spain generativas (CIBERNED), Institute of Biomedicine of
the University of Barcelona (IBUB), and Department
Miriam E. Bocarsly Section on Neuronal Structure,
of Biochemistry and Molecular Biology, Faculty of
Laboratory for Integrative Neuroscience, National
Biology, University of Barcelona, Barcelona, Spain
Institute on Alcohol Abuse and Alcoholism, National
Institutes of Health, Bethesda, MD, USA Vicent Casadó Centro de Investigación Biomédica en Red
sobre Enfermedades Neurodegenerativas (CIBERNED),
Marie-Laure Bocca Normandie University, France;
Institute of Biomedicine of the University of Barcelona
University of Caen Basse-Normandie, COMETE, Caen,
(IBUB), and Department of Biochemistry and Molecular
France; INSERM, U1075 COMETE, Caen, France
Biology, Faculty of Biology, University of Barcelona,
Roberta Bonafede Bologna University, Bologna, Italy
Barcelona, Spain
Dasiel O. Borroto-Escuela Department of Neuroscience,
Mauro Ceccanti Department of Clinical Medicine,
Karolinska Institutet, Stockholm, Sweden
Sapienza-University of Rome, Viale dell’ Università,
Edoardo Bottoni Legal Medicine Section, SAIMLAL Rome, Italy
Department, SAPIENZA University of Rome, Viale
Yong-Yuan Chang Department of Public Health,
Regina Elena, Rome, Italy
Kaohsiung Medical University, Kaohsiung City, Taiwan,
M. Bousoño Centro de Investigación Biomédica en Red de Republic of China
Salud Mental (CIBERSAM), Department of Psychiatry,
Young-Tae Chang Department of Chemistry & MedChem
University of Oviedo, Oviedo, Spain
Program of Life Sciences Institute, National University
Michael T. Bowen NHMRC Peter Doherty Biomedical of Singapore, Singapore; Singapore Bioimaging
Fellow, School of Psychology, Faculty of Science, Consortium, Agency for Science, Technology and
University of Sydney, Sydney, NSW, Australia Research (A*STAR), Singapore
Placido Bramanti Neurorobotic Rehabilitation Unit, Meng-Chun Chiu Department of Psychology, Chung-
IRCCS Centro Neurolesi “Bonino-Pulejo”, Messina, Italy Shan Medical University, Taichung, Taiwan
Kari J. Buck Department of Behavioral Neuroscience, Nan-Ying Chiu Department of Psychiatry, Lu-Tung
School of Medicine, Oregon Health & Science Christian Hospital, Lugang Town, Changhua County,
University, Portland, OR, United States; Department Taiwan
of Veterans Affairs Medical Center, Oregon Health &
Zang-Hee Cho Advanced Institutes of Convergence
Science University, Portland, OR, United States
Technology, Seoul National University, Suwon, Korea
Femke T.A. Buisman-Pijlman Discipline of Pharmacology,
Yemina Chung School of Chinese Medicine, The Chinese
Faculty of Health Sciences, University of Adelaide,
University of Hong Kong, Shatin, New Territories,
Adelaide, SA, Australia
Hong Kong; Department of Anatomy and Cell Biology,
Andreas Büttner Institute of Forensic Medicine/ McGill University, Montreal, QC, Canada
Rechtsmedizin, Rostock University Medical Center,
Costantino Ciallella Legal Medicine Section, SAIMLAL
Rostock, Germany
Department, SAPIENZA University of Rome, Viale
Rocco S. Calabrò Neurorobotic Rehabilitation Unit, Regina Elena, Rome, Italy
IRCCS Centro Neurolesi “Bonino-Pulejo”, Messina,
Eduardo Cinosi Department of Neuroscience, Imaging
Italy
and Clinical Sciences, University “G. d’Annunzio”,
Ulaş M. Çamsari Department of Psychiatry & Psychology, Chieti, Italy
Mayo Clinic College of Medicine, Rochester, MN, USA
Katherine M. Conigrave Drug Health Services, Sydney
Simone Cappelletti Legal Medicine Section, SAIMLAL Local Health District, Sydney, Australia; Discipline of
Department, SAPIENZA University of Rome, Viale Addiction Medicine, Sydney Medical School, University
Regina Elena, Rome, Italy of Sydney, Sydney, Australia
María Carbo-Gas Área de Psicobiología, Universitat Andrew N. Coogan Maynooth University Department of
Jaume I, Castellon de la Plana, Spain Psychology, National University of Ireland, Maynooth,
County Kildare, Ireland
Paola Casadio Mental Health and Pathological Addictions
Department of Ravenna, Mental Health Center of Maurizio Coppola Department of Addiction, ASL CN2,
Faenza, Faenza, Ravenna, Italy Alba, CN, Italy
List of Contributors xxvii
Antoni Cortés Centro de Investigación Biomédica en Red Chiu-Ping Fang Center for Neuropsychiatric Research,
sobre Enfermedades Neurodegenerativas (CIBERNED), National Health Research Institutes, Miaoli, Taiwan
Institute of Biomedicine of the University of Barcelona
Lir-Wan Fan Department of Pediatrics, Division of
(IBUB), and Department of Biochemistry and Molecular
Newborn Medicine, University of Mississippi Medical
Biology, Faculty of Biology, University of Barcelona,
Center, Jackson, MS, USA
Barcelona, Spain
Ahsana Dar Farooq H.E.J. Research Institute of
Giulia Costa Department of Biomedical Sciences, Section
Chemistry, International Center for Chemical and
of Neuropsychopharmacology, University of Cagliari,
Biological Sciences, University of Karachi, Karachi,
Cagliari, Italy
Pakistan; Hamdard Al-Majeed College of Eastern
Stephen Cox Department of Oral Surgery, Faculty of Medicine, Hamdard University, Karachi, Pakistan
Dentistry, University of Sydney, NSW, Australia
Daniel Feingold Addiction Medicine and Dual Diagnosis
Nachum Dafny Department of Neurobiology and Services, Department of Psychiatry, Sheba Medical
Anatomy, The University of Texas, McGovern Medical Center, Tel Hashomer, Israel; Ariel University, Israel
School at Houston, Houston, TX, USA
Luca Ferraro Department of Life Sciences and
Subhash Das Department of Psychiatry, Government Biotechnology, University of Ferrara, Ferrara, Italy;
Medical College and Hospital, Chandigarh, India LTTA Centre, University of Ferrara, Ferrara, Italy
Jonathan M. Davis Department of Psychiatry, University of Daniela Fialová Department of Geriatrics and Gerontology,
Colorado Anschutz Medical Campus, Denver, CO, USA 1st Faculty of Medicine, Charles University in Prague,
Prague, Czech Republic; Department of Social and Clinical
Robert De Matteo Department of Anatomy and
Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles
Developmental Biology, Monash University, Clayton,
University in Prague, Prague, Czech Republic
VIC, Australia
Malgorzata Filip Laboratory of Drug Addiction
Zsolt Demetrovics Institute of Psychology, Eötvös Loránd
Pharmacology, Department of Pharmacology, Institute
University, Budapest, Hungary
of Pharmacology, Polish Academy of Sciences,
Apo Demirkol Drug and Alcohol Services, Surry Hills,
Kraków, Poland; Department of Toxicology, Faculty of
Sydney, Australia; School of Public Health and
Pharmacy, Jagiellonian University College of Medicine,
Community Medicine, University of New South Wales,
Kraków, Poland
Sydney, Australia
Ebru Findikli Department of Psychiatry, School of
Eileen M. Denovan-Wright Department of Pharmacology,
Medicine, Kahramanmaras Sutcuımam University,
Dalhousie University, Halifax, NS, Canada
Kahramanmaras, Turkey
Massimo di Giannantonio Department of Neuroscience,
Roberta Finocchiaro Research Unit in Affective and
Imaging and Clinical Sciences, University
Social Neuroscience, Department of Psychology,
“G. d’Annunzio”, Chieti, Italy
Catholic University of Milan, Milan, Italy
Tuba Edgunlu Mugla Sitki Kocman University,
Paola A. Fiore Legal Medicine Section, SAIMLAL
Department of Medical Biology, School of Medicine,
Department, SAPIENZA University of Rome, Viale
Mugla, Turkey
Regina Elena, Rome, Italy
Simon Elliott ROAR Forensics Ltd, Malvern,
Sílvia Font-Mayolas Department of Psychology, Quality
Worcestershire, United Kingdom
of Life Research Institute, University of Girona, Girona,
Nicole M. Enman Department of Pharmacology and Catalonia, Spain
Physiology, Drexel University College of Medicine,
Jonah Fox New York State/American Program, Sackler
Philadelphia, PA, USA
School of Medicine, Tel Aviv, Israel
Ali A. Ensafi Department of Chemistry, Isfahan University
Domniki Fragou Laboratory of Forensic Medicine and
of Technology, Isfahan, Iran
Toxicology, School of Medicine, Aristotle University of
Marco Faccini Department of Internal Medicine, Addiction Thessaloniki, Thessaloniki, Greece
Unit, University Hospital of Verona, Verona, Italy
Qiang Fu Department of Anesthesiology, The General
Brian A. Falls Harvard Medical School Program in Hospital of Chinese People’s Liberation Army, Beijing,
Psychiatry and the Law, Beth Israel Deaconess Medical PR China
Center, Boston, MA, USA; Private Practice, Austin, TX,
Kjell Fuxe Department of Neuroscience, Karolinska
USA
Institutet, Stockholm, Sweden
xxviii List of Contributors
Maximilian Gahr Department of Psychiatry and Thaddeus A. Herzog Cancer Prevention & Control
Psychotherapy III, University of Ulm, Ulm, Germany Program, University of Hawaii Cancer Center, Honolulu,
HI, USA
M.P. García-Portilla Centro de Investigación Biomédica
en Red de Salud Mental (CIBERSAM), Department of Esmaeil Heydari-Bafrooei Department of Chemistry,
Psychiatry, University of Oviedo, Oviedo, Spain Faculty of Science, Vali-e-Asr University of Rafsanjan,
Rafsanjan, Iran
Preeta George Department of Anesthesiology, Washington
University in Saint Louis, Saint Louis, MO, USA Kiichi Hirota Department of Anesthesiology, Kansai
Medical University, Hirakata, Osaka, Japan
Isis Gil-Miravet Área de Psicobiología, Universitat Jaume I,
Castellon de la Plana, Spain Ming-Chou Ho Department of Psychology, Chung-
Shan Medical University, Taichung, Taiwan; Clinical
Philip Gorwood INSERM U894 Team 1, Centre de
Psychological Room, Chung-Shan Medical University
Psychiatrie et de Neurosciences (CPN), Paris, France;
Hospital, Taichung, Taiwan
CMME, Hospital Sainte-Anne, Paris Descartes
University, Sorbonne Paris-Cité, France Leonard L. Howell Yerkes National Primate Research
Center, Emory University, Atlanta, GA, USA
Maria Eugènia Gras Department of Psychology, Quality
of Life Research Institute, University of Girona, Girona, Wen-Yu Hsu Department of Psychiatry, Changhua
Catalonia, Spain Christian Hospital, Changhua City, Changhua County,
Taiwan
María Clara Gravielle Instituto de Investigaciones
Farmacológicas, Consejo Nacional de Investigaciones Chieh-Liang Huang Department of Addiction Psychiatry,
Científicas, Universidad de Buenos Aires, Buenos Aires, China Medical University Hospital, Taichung,
Argentina Taiwan
Mark D. Griffiths Psychology Division, Nottingham Robert N. Hughes Department of Psychology, University
Trent University, Nottingham, UK of Canterbury, Christchurch, New Zealand
Paul S. Haber Drug Health Services, Sydney Local Health Kristen A. Hymel Department of Biology, Torrey Pines
District, Sydney, Australia; Discipline of Addiction Institute for Molecular Studies, Port St. Lucie, FL,
Medicine, Sydney Medical School, University of USA
Sydney, Sydney, Australia
Gi Jung Hyun Department of Psychiatry, Chung Ang
Natalie A. Hadad Department of Psychology, University University Hospital, Dong Jack-gu, Seoul, Republic of
of Florida, Gainesville, FL, USA Korea
F. Scott Hall Department of Pharmacology and Experimental Koichi Inoue Laboratory of Clinical and Analytical
Therapeutics, College of Pharmacy and Pharmaceutical Chemistry, College of Pharmaceutical Sciences,
Sciences, University of Toledo, Toledo, OH, USA Ritsumeikan University, Kusatsu, Shiga, Japan
Doug Hyun Han Department of Psychiatry, Chung Ang M. Mofizul Islam Division of Health Services Research,
University Hospital, Dong Jack-gu, Seoul, Republic of Research School of Population Health, The Australian
Korea National University, Canberra, Australia; Australian
Primary Health Care Research Institute, Research
Richard Harding Department of Anatomy and
School of Population Health, The Australian National
Developmental Biology, Monash University, Clayton,
University, Canberra, Australia
VIC, Australia
Bardia Jamali Biopharmaceutics and Pharmacokinetic
Rida Hashmi University of Toronto, Toronto, ON, Canada
Division, Department of Pharmaceutics, Faculty of
Hossein Hassanian-Moghaddam Department of Clinical
Pharmacy, Tehran University of Medical Sciences,
Toxicology, Loghman-Hakim Hospital, Shahid Beheshti
Tehran, Iran
University of Medical Sciences, Tehran, Iran
Grażyna Jerzemowska Department of Animal and Human
Olga Hernández-Serrano Department of Physiotherapy,
Physiology, University of Gdansk, Gdansk, Poland
Escola Universitària de la Salutil’Esport (EUSES),
Martin O. Job National Institute on Drug Abuse, National
University of Girona, Girona, Catalonia, Spain
Institutes of Health, Baltimore, MD, USA
Evan S. Herrmann Behavioral Pharmacology Research
Jan Olav Johannessen Division of Psychiatry, University
Unit, Department of Psychiatry and Behavioral
of Stavanger/Stavanger University Hospital, Stavanger,
Science, Johns Hopkins University School of Medicine,
Norway
Baltimore, MD, USA
List of Contributors xxix
Helen J. Johansen Department of Epidemiology and Maryse Lapeyre-Mestre UMR-1027, INSERM-Université
Community Medicine, Faculty of Medicine, University Toulouse III, Pharmacoépidémiologie, Faculté de
of Ottawa, Ottawa, ON, Canada Médecine, Toulouse, France; Centre d’Evaluation
et d’Information sur la Pharmacodépendance-
Matthew W. Johnson Behavioral Pharmacology Research
Addictovigilance, Service de Pharmacologie Clinique,
Unit, Department of Psychiatry and Behavioral
Hôpitaux de Toulouse, Faculté de Médecine, Toulouse,
Science, Johns Hopkins University School of Medicine,
France
Baltimore, MD, USA
Edward C. Lauterbach Department of Psychiatry and
Patrick S. Johnson Behavioral Pharmacology Research
Behavioral Sciences, School of Medicine, Mercer
Unit, Department of Psychiatry and Behavioral
University, Macon, GA, USA
Science, Johns Hopkins University School of Medicine,
Baltimore, MD, USA Yann Le Strat Hospital Louis Mourier, Université Paris
Diderot, Sorbonne Paris Cité, Colombes, France;
Chang-Ki Kang Department of Radiological Science,
INSERM U894 Team 1, Centre de Psychiatrie et de
Gachon University, Incheon, Korea
Neurosciences (CPN), Paris, France
Sevim Karakaş-Çelik Department of Medical Biology,
Chen-Yi Lee Department of Oral Hygiene, Kaohsiung
School of Medicine, Bulent Ecevit University,
Medical University, Kaohsiung City, Taiwan, Republic
Zonguldak, Turkey
of China
Natasha Kharas Department of Neurobiology and
Michel Lejoyeux Department of Psychiatry, Paris 7
Anatomy, The University of Texas, McGovern Medical
University, Hospital Bichat Claude Bernard, AP-HP and
School at Houston, Houston, TX, USA
Maison Blanche Hospital, France
Young-Bo Kim Department of Neurosurgery, Gachon
Roberto Leone Pharmacology Unit, University of Verona,
University Gil Hospital, Gachon University, Incheon,
Verona, Italy
Korea
Shaul Lev-Ran Addiction Medicine and Dual Diagnosis
Lori A. Knackstedt Department of Psychology, University
Services, Department of Psychiatry, Sheba Medical
of Florida, Gainesville, FL, USA
Center, Tel Hashomer, Israel; Sackler Faculty of
Hannu Kokki Department of Anaesthesiology and
Medicine, Tel Aviv University, Tel Aviv, Israel; Centre
Intensive Care Medicine, University of Eastern Finland,
for Addiction and Mental Health, Toronto, ON, Canada
Kuopio, Finland
Ren-Hau Li Department of Psychology, Chung-Shan
Merja Kokki Department of Anaesthesia and Operative
Medical University, Taichung, Taiwan
Services, Kuopio University Hospital, Kuopio,
Willmann Liang Institute of Chinese Medicine, The
Finland
Chinese University of Hong Kong, Shatin, New
Anna Konopka Department of Psychiatry and Clinical
Territories, Hong Kong
Psychology, Pomeranian Medical University, Szczecin,
Jiajun Liu Discipline of Physiology, Faculty of Health
Poland
Sciences, University of Adelaide, Adelaide, SA,
Kathleen Kopcza Division of Pharmacy, Baystate
Australia
Children’s Hospital, Springfield, MA, USA
Ling-Jun Liu Department of Psychology, Chung-Shan
Dimitrios Kouvelas Department of Pharmacology
Medical University, Taichung, Taiwan
and Clinical Pharmacology, Aristotle University of
Liwei Liu Department of Anesthesiology, Shanghai 10th
Thessaloniki, University Campus, Thessaloniki,
People’s Hospital, 10th People’s Hospital of Tongji
Greece
University, Tongji University School of Medicine,
Leda Kovatsi Laboratory of Forensic Medicine and
Shanghai, PR China
Toxicology, School of Medicine, Aristotle University of
Sheng-Wen Liu Center for Neuropsychiatric Research,
Thessaloniki, Thessaloniki, Greece
National Health Research Institutes, Miaoli, Taiwan
Lauren C. Kruse Department of Behavioral Neuroscience,
Yu-Li Liu Center for Neuropsychiatric Research, National
School of Medicine, Oregon Health & Science
Health Research Institutes, Miaoli, Taiwan; Graduate
University, Portland, OR, United States; Department
Institute of Clinical Medical Science, China Medical
of Veterans Affairs Medical Center, Oregon Health &
University, Taichung, Taiwan
Science University, Portland, OR, United States
Zia Li Department of Psychiatry, University of California
Chien-Wen Lai Department of Life Science, National
San Diego, La Jolla, CA, USA
Tsing Hua University, Hsinchu, Taiwan
xxx List of Contributors
Daniela S.S. Lobo Department of Psychiatry, University Robert Moore Department of Anesthesiology, Washington
of Toronto, Clinician-Scientist, Centre for Addiction University in Saint Louis, Saint Louis, MO, USA
and Mental Health, Campbell Family Mental Health
Micaela Morelli Department of Biomedical Sciences,
Research Institute, Toronto, ON, Canada
Section of Neuropsychopharmacology, University of
Jingsheng Lou Department of Anesthesiology, The Cagliari, Cagliari, Italy
General Hospital of Chinese People’s Liberation Army,
Estefanía Moreno Centro de Investigación Biomédica
Beijing, PR China
en Red sobre Enfermedades Neurodegenerativas
Rocco Luigi Picci Department of Clinical and Biological (CIBERNED), Institute of Biomedicine of the University
Sciences, San Luigi Gonzaga Medical School University of Barcelona (IBUB), and Department of Biochemistry
of Turin, Torino, Italy and Molecular Biology, Faculty of Biology, University
of Barcelona, Barcelona, Spain
Matteo Lupi Department of Neuroscience, Imaging and
Clinical Sciences, University “G. d’Annunzio”, Chieti, Italy Tomohisa Mori Department of Toxicology, Hoshi
University School of Pharmacy and Pharmaceutical
Brianna M. Lutz Department of Anesthesiology, New
Sciences, Shinagawa-ku, Tokyo, Japan
Jersey Medical School, Rutgers, The State University of
New Jersey, Newark, NJ, USA Bridin Murnion Drug Health Services, Sydney Local
Health District, Sydney, Australia; Discipline of
Kendra MacClurg Wayne County Action Program
Addiction Medicine, Sydney Medical School, University
Success Center Transitional House, Newark, NY, USA
of Sydney, Sydney, Australia
Lara Magro Pharmacology Unit, University of Verona,
Kelle L. Murphy Department of Kinesiology and
Verona, Italy
Rehabilitation Science, University of Hawaii at Manoa,
Mirko Manchia Section of Psychiatry, Department of Public
Honolulu, HI, USA
Health, Clinical and Molecular Medicine, University
Bhushan Vijay Nagpure Department of Pharmacology,
of Cagliari, Cagliari, Sardinia, Italy; Department of
Yong Loo Lin School of Medicine, National University
Pharmacology, Dalhousie University, Halifax, NS, Canada
of Singapore, Singapore
Aniko Maraz Institute of Psychology, Eötvös Loránd
Antonino Naro Neurorobotic Rehabilitation Unit, IRCCS
University, Budapest, Hungary
Centro Neurolesi “Bonino-Pulejo”, Messina, Italy
Rémi Martin-Fardon Department of Molecular and
C. Ineke Neutel Department of Epidemiology and
Cellular Neuroscience, The Scripps Research Institute,
Community Medicine, Faculty of Medicine, University
La Jolla, CA, USA
of Ottawa, Ottawa, ON, Canada
Giovanni Martinotti Department of Neuroscience, Imaging
Suzanne Nielsen National Drug and Alcohol Research
and Clinical Sciences, University “G. d’Annunzio”,
Centre, University of New South Wales, Sydney,
Chieti, Italy
Australia; Drug and Alcohol Services, Surry Hills,
Alessandra Matzeu Department of Molecular and Cellular
Sydney, Australia
Neuroscience, The Scripps Research Institute, La Jolla,
Motoo Nomura Department of Therapeutic Oncology,
CA, USA
Kyoto University Graduate School of Medicine, Kyoto,
Jay P. McLaughlin Department of Biology, Torrey Pines
Japan
Institute for Molecular Studies, Port St. Lucie, FL, USA
Francesco Oliva Department of Clinical and Biological
Ian S. McRae Australian Primary Health Care Research
Sciences, San Luigi Gonzaga Medical School University
Institute, Research School of Population Health, The
of Turin, Torino, Italy
Australian National University, Canberra, Australia
M. Foster Olive Department of Psychology, Arizona State
Dieter J. Meyerhoff Center for Imaging of Neuro-
University, Tempe, AZ, USA
degenerative Diseases (CIND), DVA Medical Center,
Deanna Olivoni Mental Health and Pathological
University of California San Francisco (UCSF),
Addictions Department of Ravenna, Pathological
San Francisco, CA, USA
Addictions of Faenza, Faenza, Ravenna, Italy
Marta Miquel Área de Psicobiología, Universitat Jaume I,
Qin Ouyang Department of Pharmaceutical Sciences,
Castellon de la Plana, Spain
Computational Chemical Genomics Screening Center,
Raffaella Mondola Department of Mental Health, ASL
School of Pharmacy, NIDA National Center of
CN1, Saluzzo, CN, Italy
Excellence for Computational Drug Abuse Research,
List of Contributors xxxi
University of Pittsburgh, Pittsburgh, PA, USA; Joint Francesco S. Romolo Legal Medicine Section,
CMU-Pitt Ph.D. Computational Biology Program, SAIMLAL Department, SAPIENZA University of
University of Pittsburgh, Pittsburgh, PA, USA; Drug Rome, Viale Regina Elena, Rome, Italy; Institut de
Discovery Institute, University of Pittsburgh, Pittsburgh, Police Scientifique, Université de Lausanne, Batiment
PA, USA Batochimie, Lausanne, Switzerland
Ståle Pallesen Department of Psychosocial Science, Ali Roohbakhsh Pharmaceutical Research Center, School
University of Bergen, Bergen, Norway of Pharmacy, Mashhad University of Medical Sciences,
Mashhad, Iran
Aurore Palmaro UMR-1027, INSERM-Université
Toulouse III, Pharmacoépidémiologie, Faculté de Mohammadreza Rouini Biopharmaceutics and Pharmaco-
Médecine, Toulouse, France kinetic Division, Department of Pharmaceutics, Faculty of
Pharmacy, Tehran University of Medical Sciences, Tehran,
Georgios Papazisis Department of Pharmacology
Iran
and Clinical Pharmacology, Aristotle University of
Thessaloniki, University Campus, Thessaloniki, Greece Anne Roussin UMR-1027, INSERM-Université Toulouse
III, Pharmacoépidémiologie, Faculté de Médecine,
Jason J. Paris Department of Biology, Torrey Pines
Toulouse, France; Centre d’Evaluation et d’Information
Institute for Molecular Studies, Port St. Lucie,
sur la Pharmacodépendance-Addictovigilance, Service
FL, USA
de Pharmacologie Clinique, Hôpitaux de Toulouse,
Chan-A Park Bioimaging Research Team, Division of
Faculté de Médecine, Toulouse, France
Bioconvergence Analysis, Korea Basic Science Institute,
Florence F. Roussotte Department of Neurology, David
Ochang, Cheongju, Korea
Geffen School of Medicine, University of California,
Jeong Ha Park Department of Psychiatry, Chung Ang
Los Angeles (UCLA), Los Angeles, CA, USA
University Hospital, Dong Jack-gu, Seoul, Republic of
P.A. Saiz Centro de Investigación Biomédica en Red de
Korea
Salud Mental (CIBERSAM), Department of Psychiatry,
Justyna Pełka Wysiecka Department of Psychiatry and
University of Oviedo, Oviedo, Spain
Clinical Psychology, Pomeranian Medical University,
J. Samochowiec Department of Psychiatry and Clinical
Szczecin, Poland
Psychology, Pomeranian Medical University, Szczecin,
Verity Pearson-Dennett School of Pharmacy and Medical
Poland
Sciences and Sansom Institute, University of South
Carla Sanchis-Segura Área de Psicobiología, Universitat
Australia, Adelaide, SA, Australia
Jaume I, Castellon de la Plana, Spain
Daniel E. Phillips Department of Psychiatry and
Rita Santacroce Department of Neuroscience, Imaging and
Behavioral Sciences, School of Medicine, Mercer
Clinical Sciences, University “G. d’Annunzio”, Chieti, Italy
University, Macon, GA, USA
Carmen Sato-Bigbee Department of Biochemistry, and
Martina Pinna Psychiatry Unit, San Martino Hospital –
Molecular Biology, Virginia Commonwealth University,
Health Agency N. 5, Oristano, Sardinia, Italy
School of Medicine, Richmond, VA, USA
Paul L. Plener Department of Child and Adolescent
Psychiatry and Psychotherapy, University of Ulm, Ulm, H. Umit Sayin Cerrahpaşa Medical Faculty, Institute
Germany of Forensic Sciences, İstanbul University, Aksaray,
İstanbul, Turkey
Nicolas Ramoz INSERM U894 Team 1, Centre de
Veronica B. Searles Quick Department of Biochemistry
Psychiatrie et de Neurosciences (CPN), Paris, France
and Molecular Genetics, University of Colorado
Perry F. Renshaw Department of Psychiatry, Brain
Anschutz Medical Campus, Aurora, CO, USA
Institute, University of Utah, Salt Lake City, UT, USA
Ömer Şenormanci Department of Psychiatry, School of
Beverly A.S. Reyes Department of Pharmacology and
Medicine, Bulent Ecevit University, Zonguldak, Turkey
Physiology, Drexel University College of Medicine,
Emmanuel Seseña Facultad de Medicina, Benemérita
Philadelphia, PA, USA
Universidad Autónoma de Puebla, México
Alicia Rivera Facultad de Ciencias, Instituto de
Ali Shamsizadeh Physiology-pharmacology Research
Investigación Biomédica, Universidad de Málaga,
Center, Rafsanjan University of Medical Sciences,
Málaga, Spain
Rafsanjan, Iran
Susan E. Robinson Department of Pharmacology and
Behjat Sheikholeslami Faculty of Pharmacy, Lorestan
Toxicology Virginia Commonwealth University School
University of Medical Sciences, Khorramabad, Iran
of Medicine, Richmond, VA, USA
xxxii List of Contributors
Bin Shen Department of Psychology, Chung-Shan Medical Johannes Thome Department of Psychiatry, School of
University, Taichung, Taiwan Medicine, University of Rostock, Rostock, Germany
Masahiro Shibasaki Department of Toxicology, Hoshi Paul M. Thompson Departments of Neurology,
University School of Pharmacy and Pharmaceutical Psychiatry, Radiology, Engineering, Pediatrics, and
Sciences, Shinagawa-ku, Tokyo, Japan Ophthalmology, Keck School of Medicine, University
of Southern California, Los Angeles, CA, USA
Samuel D. Shillcutt Department of Psychiatry and
Behavioral Sciences, School of Medicine, Mercer Lu-Tai Tien School of Medicine, Fu Jen Catholic
University, Macon, GA, USA University, New Taipei City, Taiwan
Nicola Simola Department of Biomedical Sciences, Elizabeth I. Tietz Department of Physiology and
Section of Neuropsychopharmacology, University of Pharmacology, University of Toledo College of Medicine,
Cagliari, Cagliari, Italy Toledo, OH, USA; Department of Neurosciences,
University of Toledo College of Medicine, Toledo, OH,
Rachana Singh Division of Newborn Medicine, Baystate
USA
Children’s Hospital, Springfield, MA, USA
Gabrielle Todd School of Pharmacy and Medical Sciences
Amuchou Singh Soraisham Department of Pediatrics,
and Sansom Institute, University of South Australia,
Cumming School of Medicine, University of Calgary,
Adelaide, SA, Australia
Calgary, AB, Canada
Mary Tolcos The Ritchie Centre, Hudson Institute of
Enrique Soto Instituto de Fisiología, Benemérita
Medical Research, Clayton, VIC, Australia; Department
Universidad Autónoma de Puebla, México
of Obstetrics and Gynecology, Monash University,
Michael Soyka Psychiatrische Klinik, Universität
Clayton, VIC, Australia; School of Health and
München, Munich, Germany; Privatklinik Meiringen,
Biomedical Sciences, RMIT University, Bundoora,
Meiringen, Switzerland
VIC, Australia
Ainars Stepens Laboratory for Research in Rehabilitation,
Meshkat Torkamanian Student Scientific Research Center,
Riga Stradins University, Riga, Latvia
Tehran University of Medical Sciences, Tehran, Iran
Mark J.M. Sullman System Engineering & Human
Jieh-Hen Tsung Center for Neuropsychiatric Research,
Factors, Cranfield University, Bedfordshire, UK
National Health Research Institutes, Miaoli, Taiwan
Linlin Sun Department of Anesthesiology, New Jersey
Sergio Tufik Department of Psychobiology, Universidade
Medical School, Rutgers, The State University of New
Federal de São Paulo (UNIFESP), Sao Paulo, SP,
Jersey, Newark, NJ, USA
Brazil
Tsutomu Suzuki Department of Toxicology, Hoshi
Mafaz Ullah The Cellular and Molecular Pathology
University School of Pharmacy and Pharmaceutical
Research Unit, Oral Pathology and Oral Medicine,
Sciences, Shinagawa-ku, Tokyo, Japan
Faculty of Dentistry, University of Sydney, NSW,
Attila Szabo Institute of Health Promotion and Sport Australia
Sciences, Eötvös Loránd University, Budapest, Hungary
Fabio Vaiano Department of Health Sciences, Division of
Pille Taba Department of Neurology and Neurosurgery, Forensic Toxicology, University of Florence, Florence,
University of Tartu, Tartu, Estonia Italy
Hong Chai Tang School of Chinese Medicine, The Elisabeth J. Van Bockstaele Department of Pharmacology
Chinese University of Hong Kong, Shatin, New and Physiology, Drexel University College of Medicine,
Territories, Hong Kong Philadelphia, PA, USA
Tze-Chun Tang Department of Psychiatry, Kaohsiung Ryan Vandrey Behavioral Pharmacology Research Unit,
Medical University Chung-Ho Memorial Hospital, Department of Psychiatry and Behavioral Science, Johns
Kaohsiung, Taiwan Hopkins University School of Medicine, Baltimore,
MD, USA
Yuan-Xiang Tao Department of Anesthesiology, New
Jersey Medical School, Rutgers, The State University of Dolores Vazquez-Sanroman Área de Psicobiología,
New Jersey, Newark, NJ, USA Universitat Jaume I, Castellon de la Plana, Spain;
Department of Psychology, Biomedical/Biological
Wenche ten Velden Hegelstad Division of Psychiatry,
Sciences Research Building (BBSR), University of
University of Stavanger/Stavanger University Hospital,
Kentucky, Lexington, KY, USA
Stavanger, Norway