Neuromuscular Disorders: A Symptoms and Signs Approach to Differential Diagnosis and Treatment PDF
Preview Neuromuscular Disorders: A Symptoms and Signs Approach to Differential Diagnosis and Treatment
Neuromuscular Disorders Neuromuscular Disorders A Symptoms and Signs Approach to Differential Diagnosis and Treatment Editor Nicholas J. Silvestri, MD Associate Professor of Neurology Department of Neurology University at Buffalo Jacobs School of Medicine & Biomedical Sciences Buffalo, New York An Imprint of Springer Publishing Visit our website at www.springerpub.com ISBN: 9780826171986 ebook ISBN: 9780826171993 Acquisitions Editor: Beth Barry Compositor: Exeter Premedia Services Private Ltd. Copyright © 2018 Springer Publishing Company. Demos Medical Publishing is an imprint of Springer Publishing Company, LLC. All rights reserved. This book is protected by copyright. No part of it may be repro- duced, stored in a retrieval system, or transmitted in any form or by any means, elec- tronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher. Medicine is an ever-changing science. Research and clinical experience are continually expanding our knowledge, in particular our understanding of proper treatment and drug therapy. The authors, editors, and publisher have made every effort to ensure that all information in this book is in accordance with the state of knowledge at the time of production of the book. Nevertheless, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the contents of the publication. Every reader should examine carefully the package inserts accompanying each drug and should carefully check whether the dosage sched- ules mentioned therein or the contraindications stated by the manufacturer differ from the statements made in this book. Such examination is particularly important with drugs that are either rarely used or have been newly released on the market. Library of Congress Cataloging-in-Publication Data Names: Silvestri, Nicholas J., editor. Title: Neuromuscular disorders: a symptoms and signs approach to differential diagnosis and treatment / Nicholas J. Silvestri, editor. Other titles: Neuromuscular disorders (Silvestri) Description: New York: Demos Medical Publishing/Springer Publishing Company, [2018] | Includes bibliographical references and index. Identifi ers: LCCN 2017034196 | ISBN 9780826171986 | ISBN 9780826171993 (e-book) Subjects: | MESH: Neuromuscular Diseases—diagnosis | Neuromuscular Diseases—therapy Classifi cation: LCC RC925.55 | NLM WE 550 | DDC 616.7/44—dc23 LC record available at https://lccn.loc.gov/2017034196 Contact us to receive discount rates on bulk purchases. We can also customize our books to meet your needs. For more information please contact: [email protected] Printed in the United States of America by McNaughton & Gunn. 17 18 19 20 21 / 5 4 3 2 1 For my students, teachers, colleagues, and especially for my family Contents Contributors ix Foreword Gil I. Wolfe, MD xi Preface xiii Share Neuromuscular Disorders: A Symptoms and Signs Approach to Differential Diagnosis and Treatment 1. Interpretation of Tests Used in Neuromuscular Disorders 1 Diana Mnatsakanova and David Lacomis 2. Acute Generalized Weakness 41 Simona Treidler and Yaacov Anziska 3. Subacutely Developing Weakness 61 Mamatha Pasnoor, Mazen M. Dimachkie, and Richard J. Barohn 4. Chronically Developing Weakness 91 Hans D. Katzberg, Ari Breiner, and Aaron Izenberg 5. Episodic Weakness and Exercise Intolerance 107 Carolina Barnett and Charles Kassardjian 6. Ocular and Bulbar Symptoms 123 Michael K. Hehir 7. Neuromuscular Respiratory Failure 145 Nicholas J. Silvestri, Karin Provost, and Daniel W. Sheehan 8. Sensory Loss and Neuropathic Pain 163 Kelly G. Gwathmey and Nora Jovanovich 9. Limb Pain 201 Andrew W. Tarulli Index 217 vii Contributors Yaacov Anziska, MD, MS, Assistant Professor of Neurology, Department of Neurology, SUNY Downstate Medical Center, Brooklyn, New York Carolina Barnett, MD, PhD, Assistant Professor, Division of Neurology, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada Richard J. Barohn, MD, Gertrude and Dewey Ziegler Professor of Neurology, University Distinguished Professor, Vice Chancellor for Research, President, Research Institute, University of Kansas Medical Center, Kansas City, Kansas Ari Breiner, MD, MSc, FRCPC, Assistant Professor, Division of Neurology, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada Mazen M. Dimachkie, MD, Professor of Neurology, Director, Neuromuscular Division, Executive Vice Chairman and Vice Chairman for Research Programs, Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas Kelly G. Gwathmey, MD, Assistant Professor of Neurology, Department of Neurology, University of Virginia, Charlottesville, Virginia Michael K. Hehir, MD, Associate Professor, Division Chief, Neuromuscular Medicine, Department of Neurosciences, Larner College of Medicine at the University of Vermont, Burlington, Vermont Aaron Izenberg, MD, FRCPC, Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada Nora Jovanovich, MD, Department of Neurology, University of Virginia, Charlottesville, Virginia Charles Kassardjian, MD, FRCP, Division of Neurology, Department of Medicine, St. Michael’s Hospital and University of Toronto, Toronto, Ontario, Canada ix
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