Neurobiology of Disease - Academic Press

1050 Pages·2016·24.22 MB·English

by  Gilman S.

Contributors
AdrianoAguzzi,MD,PhD,DVM,hc,FRCP,FRCPath JoséBerciano
Department of Pathology, University Hospital Zurich Service of Neurology, University Hospital
Zurich, Switzerland Marqués de Valdecilla
JamesW.Albers,MD,PhD Santander, Spain
Department of Neurology, University of Michigan EdwardH.Bertram,III,MD
Medical School Department of Neurology, University of Virginia
Ann Arbor, Michigan Charlottesville, Virginia
JeffryR.Alger,PhD RadhikaBhatia,MD
Department of Neurology, Ahmanson-Lovelace Renal Research, Brigham and Women’s Hospital
Brain Mapping Center, UCLA Brain Research Institute Boston, Massachusetts
Jonsson Comprehensive Cancer Center, JoseBiller,MD
David Geffen School of Medicine, Department of Neurology, Loyola University of
University of California–Los Angeles Chicago, Stritch School of Medicine
Los Angeles, California Chicago, Illinois
RichardP.Allen,PhD GretchenL.Birbeck,MD,MPH
Department of Neurology and Sleep Medicine, International Neuropsychiatric Epidemiology Program
Johns Hopkins University (INPEP), Michigan State University
Baltimore, Maryland East Lansing, Michigan
CynthiaAranow,MD ThomasP.Bleck,MD,FCCM
Department of Medicine, Department of Neurology, Evanston Northwestern
Columbia University Medical Center Healthcare
New York, New York Evanston, Illinois
Misha-MiroslavBackonja,MD BrianP.Bosworth,MD
Department of Neurology, University of Wisconsin Department of Gastroenterology, Division of
Madison, Wisconsin Gastroenterology and Hepatology, Weill Medical
CurtisW.Balmer,PhD College of Cornell University
JBS International, Inc., National Institute on New York, New York
Drug Abuse, National Institutes of Health DavidBowsher,MD,ScD,PhD,FRCPEd,FRCPath
Bethesda, Maryland Pain Research Institute, University Department of
TracyBatchelor,MD,MPH Neurological Science, University Hospital Aintree
Department of Neurology, Harvard Medical School Liverpool, United Kingdom
Stephen E. and Catherine Pappas BenjaminBrooks,MD
Center for Neuro-Oncology, Department of Neurology, University of Wisconsin
Massachusetts General Hospital Madison, Wisconsin
Boston, Massachusetts IrenaBukelis
EduardoE.Benarroch,MD,DSci Center for Genetic Disorders of Cognition and
Department of Neurology, Mayo Clinic Behavior, Kennedy Krieger Institute
Rochester, Minnesota Baltimore, Maryland
ix
x Contributors
JohnJ.Caronna,MD RimaM.Dafer,MD,MPH
Department of Neurology and Neuroscience, Weill Department of Neurology, Loyola University of
Medical College of Cornell University Chicago, Stritch School of Medicine
New York, New York Chicago, Illinois
JohnC.Carter MarinosC.Dalakas,MD
Center for Genetic Disorders of Cognition National Institutes of Health, National Institute of
and Behavior, Kennedy Krieger Institute Neurological Disorders and Stroke, Neuromuscular
Baltimore, Maryland Diseases Section
GuidoCavaletti,MD Bethesda, Maryland
Department of Neurosciences and Biomedical JosepDalmau,MD,PhD
Technologies, University of Milan–Bicocca Division of Neuro-Oncology, University of
Monza, Italy Pennsylvania
PratapChand,DM,FRCP Philadelphia, Pennsylvania
Department of Neurology, University of Louisville AnnedeSaintMartin,MD
School of Medicine Department of Pediatric Neurology, Strasbourg
Louisville, Kentucky University Hospital
JiY.Chong,MD Strasbourg, France
Department of Neurology, Columbia University JohnA.Detre,MD
New York, New York Department of Neurology, Department of Radiology,
JamesC.Cleland,MBChB University of Pennsylvania
Department of Neurology, Highland Hospital, Philadelphia, Pennsylvania
University of Rochester School of Medicine VijayDhawan,PhD
and Dentistry Center for Neurosciences, Feinstein Institute for
Rochester, New York Medical Research, North Shore–Long Island Jewish
CarloColosimo,MD HealthSystemDepartmentofNeurologyandMedicine,
Department of Neurological Sciences, New York University School of Medicine
University of Rome “La Sapienza” Manhasset, New York
Rome, Italy BettyDiamond,MD
TimothyP.Condon,PhD Department of Medicine, Columbia University
National Institute on Drug Abuse, National Medical Center
Institutes of Health New York, New York
Bethesda, Maryland SeanPatrickAndrewsDrummond,PhD
E.SanderConnolly,Jr.,MD Department of Psychiatry, San Diego
Department of Neurological Surgery, Veterans Affairs Medical Center
Columbia Unversity San Diego, California
New York, New York DavidEidelberg,MD
GinoCortopassi,PhD Center for Neurosciences, Feinstein Institute for
Department of Molecular Biosciences, Medical Research, North Shore–Long Island Jewish
University of California–Davis School HealthSystemDepartmentofNeurologyandMedicine,
of Veterinary Medicine New York University School of Medicine
Davis, California Manhasset, New York
RonaldG.Crystal,MD JohnH.Eisenach,MD
Department of Genetic Medicine, Division of Department of Anesthesiology, Mayo Clinic College
Pulmonary and Critical Care Medicine, Weill Medical of Medicine
College of Cornell University Rochester, Minnesota
New York, New York SaidElshihabi,MD
LaurieE.Cutting,PhD Division of Neurosurgery, University of Toronto
Department of Neurology, Johns Hopkins Toronto, Ontario, Canada
University School of Medicinenl QiWenFan,PhD
Department of Education, Departments of Neurology, Pediatrics, and
Johns Hopkins University Neurological Surgery; Brain Tumor Research Center
Developmental Cognitive Neurology, and Comprehensive Cancer Center; University of
Kennedy Krieger Institute California–San Francisco
Baltimore, Maryland San Francisco, California
Contributors xi
RobertD.Fealey,MD School of Medicine and Dentistry
Department of Neurology, Mayo Clinic Rochester, New York
Rochester, Minnesota DavidH.Gutmann,MD,PhD
MichelD.Ferrari,MD,PhD Department of Neurology, Washington University
Department of Neurology, Leiden University Neurofibromatosis Center, Washington University
Medical Center Siteman Cancer Center
Leiden, Netherlands St. Louis, Missouri
DonnaM.Ferriero,MD,MS ChristianHagel,MD
Department of Neurology, Department of Pediatrics, Institute of Neuropathology, University Medical Center
University of California–San Francisco Hamburg–Eppendorf
San Francisco, California Hamburg, Germany
GereonR.Fink,MD,PhD PaulJ.Hagerman,MD,PhD
Department of Neurology–Cognitive Neurology, Department of Biochemistry and Molecular
Universitätsklinikum Aachen, Rheinisch-Westfälische Medicine, University of California–Davis
Technische Hochschule Aachen School of Medicine
Aachen, Germany Davis, California
KennethH.Fischbeck,MD KendraHarris,MSc
Neurogenetics Branch, National Institute of Department of Pediatric Neurology, Johns Hopkins
Neurological Disorders and Stroke, National Institutes University School of Medicine
of Health Baltimore, Maryland
Bethesda, Maryland Hans-PeterHartung,MD
KarenFurie,MD,MPH Department of Neurology, Heinrich Heine University
Stroke Service, Massachusetts General Hospital Düsseldorf, Germany
Boston, Massachusetts BernhardHemmer,MD
NéstorGálvez-Jiménez,MD,MSc,MHSA,FACP Department of Neurology, Heinrich Heine University
Department of Neurology, Florida Atlantic Düsseldorf, Germany
University–University of Miami Miller School FrankL.Heppner,MD
of Medicine Department of Pathology, University Hospital Zurich
Weston, Florida Zurich, Switzerland
FelixGeser,MD,PhD MarthaR.Herbert,MD,PhD
Department of Neurology, Innsbruck Medical University Department of Pediatric Neurology, Center for
Innsbruck, Austria Morphometric Analysis, Massachusetts General
MarkusGlatzel,MD Hospital, Harvard Medical School
Department of Pathology, University Hospital Zurich Charlestown, Massachusetts
Zurich, Switzerland DavidN.Herrmann,MBBCh
PeterJ.Goadsby,MD,PhD,DSc Department of Neurology, University of Rochester
Institute of Neurology, The National Hospital for School of Medicine and Dentistry
Neurology and Neurosurgery Rochester, New York
London, United Kingdom MichioHirano,MD
AlanL.Goldin,MD,PhD Department of Neurology, Columbia University
Department of Microbiology and Molecular Genetics, Medical Center
Department of Anatomy and Neurobiology, New York, New York
University of California–Irvine EdouardHirsch,MD
Irvine, California Department of Neurology, Strasbourg
KarenJ.Greenland,BSc,(Hons)PhD University Hospital
Center for Hormone Research, Murdoch Children’s Strasbourg, France
Research Institute, University of Melbourne, Royal JulianT.Hoff,MD
Children’s Hospital Victoria, Australia Department of Neurosurgery, University of Michigan
Pediatric Endocrinology Section, University of Ann Arbor, Michigan
Children’s Hospital AlexanderH.Hoon,Jr.,MD,MPH
Tuebingen, Germany Department of Pediatrics, Johns Hopkins University
RobertC.Griggs,MD School of Medicine
Department of Neurology, Phelps Center for Cerebral Palsy and
University of Rochester Neurodevelopmental Medicine,
xii Contributors
Kennedy Krieger Institute KatrinLamszus,MD
Baltimore, Maryland Department of Neurosurgery, University Medical
BradleyT.Hyman,MD,PhD Center Hamburg–Eppendorf
Department of Neurology, Massachusetts General Hamburg, Germany
Hospital, Harvard Medical School BrianR.Landzberg,MD
Charlestown, Massachusetts Division of Gastroenterology and Hepatology,
SamayJain,MD Weill Medical College of Cornell
Division of Movement Disorders, Department University
of Neurology, Columbia University New York, New York
New York, New York MichaelH.Lev,MD
WilfridJänig Department of Radiology, Massachusetts General
Physiologisches Institut, Hospital, Harvard Medical School
Christian-Albrechts-Universität Boston, Massachusetts
Kiel, Germany DavidN.Lieberman,MD,PhD
SafwanS.Jaradeh,MD Center for Genetic Disorders of Cognition and
Department of Neurology, Medical College Behavior, Kennedy Krieger Institute
of Wisconsin Division of Pediatric Neurology, Department of
Milwaukee, Wisconsin Neurology, Johns Hopkins University School of
KurtA.Jellinger,MD Medicine
Institute of Clinical Neurobiology Baltimore, Maryland
Vienna, Austria LelandE.Lim,MD,PhD
MichaelJ.Joyner,MD Department of Neurology and
Department of Anesthesiology, Mayo Clinic Neurological Sciences, Stanford University
College of Medicine School of Medicine
Rochester, Minnesota Stanford, California
WalterE.Kaufmann,MD PaulH.Lipkin,MD
Center for Genetic Disorders of Cognition and Department of Pediatrics, Johns Hopkins University
Behavior, Kennedy Krieger Institute School of Medicine
Departments of Pathology, Neurology, Pediatrics, Center for Development and Learning, Kennedy
Psychiatry and Behavioral Sciences, and Radiology Krieger Institute
and Radiological Science, Johns Hopkins University Baltimore, Maryland
School of Medicine IreneLitvan,MD
Baltimore, Maryland Department of Neurology,
RichardF.Keep,PhD University of Louisville School of Medicine
Department of Neurosurgery, Department of Louisville, Kentucky
Integrative and Molecular Physiology, ZacharyLondon,MD
University of Michigan Department of Neurology,
Ann Arbor, Michigan University of Michigan
AaronKellogg,BS Ann Arbor, Michigan
Molecular Basis of Disease, Medical College of Ohio PhillipA.Low,MD
Toledo, Ohio Department of Neurology, Mayo Clinic
BerndC.Kieseier,MD Rochester, Minnesota
Department of Neurology, Heinrich Heine University MegganMackay,MD
Düsseldorf, Germany Department of Medicine, Columbia University
StephenL.Kinsman,MD Medical Center
DepartmentsofPediatricsandNeurology,Universityof New York, New York
Maryland School of Medicine MarkW.Mahowald,MD
Baltimore, Maryland Department of Psychiatry, University of Minnesota,
HubertusKöller,MD Hennepin County Medical Center
Department of Neurology, Heinrich Heine University Minneapolis, Minnesota
Düsseldorf, Germany LuigiManzo,MD
CzeslawaKowal,PhD Department of Internal Medicine,
Department of Medicine, University of Pavia,
Columbia University Medical Center Maugeri Foundation Medical Center
New York, New York Pavia, Italy