Netter's Illustrated Human Pathology

556 Pages·146.678 MB·English

by  Buja M., Krueger G.

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Netter’s Illustrated
Human
Pathology
SECOND EDITION
L. Maximilian Buja, MD
The University of Texas Health Science Center at Houston
Gerhard R. F. Krueger, MD, PhD
The University of Texas Health Science Center at Houston
Illustrations by Frank H. Netter, MD
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Elsevier Inc.
1600 John F. Kennedy Boulevard
Suite 1800
Philadelphia, PA 19103-2899
Netter’s Illustrated Human Pathology
Second Edition ISBN: 978-0-323-22089-7
Copyright © 2014, 2005 by Saunders, an imprint of Elsevier Inc.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic
or mechanical, including photocopying, recording, or any information storage and retrieval system,
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Publisher (other than as may be noted herein).
Permission for Netter Art igures may be sought directly from Elsevier’s Health Science Licensing
Department in Philadelphia, PA: phone [phone], ext. 3276, or 215-239-3276; or email
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Notice
Knowledge and best practice in this ield are constantly changing. As new research and experience
broaden our understanding, changes in research methods, professional practices, or medical
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Practitioners and researchers must always rely on their own experience and knowledge in
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ISBN: 978-0-323-22089-7
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Publishing Services Manager: Patricia Tannian
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Printed in China
Last digit is the print number: 9 8 7 6 5 4 3 2 1
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DEDICATION
We dedicate this book to our families—especially our wives,
Donna Buja and Barbara Krueger.
Their encouragement and support have been inspirational
and fundamental in our work and our lives.
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PREFACE
Netter’s Atlas of Human Pathology is intended to bus by providing a vivid visual framework and
provide students with a clear, concise, and com- companion for the study of the causes, patho-
pelling presentation of the pathologic basis of the physiology, and natural history of disease. The
most common human diseases. Pathology is a Atlas also can be used as an adjunct when study-
science and medical discipline that deals with the ing gross and microscopic pathology specimens
causes (etiology), mechanisms (pathophysiology), in the laboratory. Additionally, the Atlas can
and interrelated anatomical, functional, and serve as an introduction to new subject matter
clinical manifestations of disease. Pathology is a and as a review after appropriate detail has been
vast ield encompassing all of human disease and learned. Thus, the Atlas is meant to be a useful
expanding geometrically to include information learning aid for students involved in their irst
from rapidly evolving advances in the basic human pathology course and a review for stu-
biomedical sciences, particularly the elucidation dents, medical residents, physicians, and other
of the human genome. However, understanding health care professionals at subsequent stages of
human disease will always require a clear under- their careers.
standing of the ultimate expression of disease as The distinguishing element of this Atlas is the
anatomical changes in tissues and organs (patho- brilliantly conceived and executed medical
logic anatomy). Therefore, this Atlas provides illustrations of the famous physician-artist, Frank
readily understandable representations of com- H. Netter, MD. As a result of a long and produc-
mon human diseases, concentrating on patho- tive career, Dr. Netter has left a legacy of a vast
logic anatomy and relating the anatomical collection of medical art familiar to physicians
changes to the functional and clinical manifesta- and other health care professionals throughout
tions of disease and their underlying causes and the world. Dr. Netter’s insight into and under-
mechanisms. standing of structure-function relations has
The initial chapter covers basic pathologic produced compelling and memorable depictions
changes encountered in organs and tissues in of the fundamental features of disease processes.
many disease processes, including degeneration The Netter illustrations are the core of the Atlas.
and atrophy; apoptosis and necrosis; acute and However, in some cases, the Netter drawings
chronic inlammation; immunologic reactions; have been supplemented with gross photographs
regeneration, hypertrophy, and hyperplasia; and and photomicrographs to enhance and complete
dysplasia and neoplasia. The following 12 chap- the picture. The chapters on general pathology,
ters deal with diseases of speciic organ systems: skin, and hematologic disorders use gross and
the cardiovascular system; respiratory system; microscopic photographs to illustrate these
gastrointestinal system; liver, gallbladder, and pathologic processes. Through the combination
pancreas; kidneys and urinary system; male and and integration of the Netter illustrations, gross
female reproductive systems; integumentary (skin) and microscopic photographs, tables, and text,
system; hematopoietic and lymphatic systems; our goal is to present students with an Atlas that
bones, joints, and soft tissues; endocrine system; enhances their knowledge, understanding, and
and nervous system. Each chapter begins with a appreciation of the pathologic basis of human
concise summary of the various pathologic pro- disease. Pathology is the fundamental bridging
cesses and diseases to be presented in the chap- discipline linking the basic biomedical sciences
ter. The main body of each chapter consists of to clinical medicine. Therefore, our ultimate goal
illustrations of pathologic processes and diseases is for our students to use their knowledge of
accompanied by concise text aimed at clarifying pathology to become scientiically grounded,
and expanding the information presented in the effective physicians and health care
illustrations. Comparative data about similar professionals.
disease processes are summarized in tables.
The Atlas is designed to complement a compre- L. Maximilian Buja, MD
hensive textbook of pathology or a course sylla- Gerhard R.F. Krueger, MD, PhD
vii
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