Nelson Textbook of Pediatrics

6882 Pages·2019·563.879 MB·English

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Nelson

TEXTBOOK OF

PEDIATRICS
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EDITION
21
Nelson

TEXTBOOK OF

PEDIATRICS
ROBERT M. KLIEGMAN, MD JOSEPH W. ST GEME III, MD
Professor and Chair Emeritus Professor of Pediatrics and Microbiology and Chair of
Department of Pediatrics the Department of Pediatrics
Medical College of Wisconsin University of Pennsylvania Perelman School of Medicine
Milwaukee, Wisconsin Chair of the Department of Pediatrics and
Physician-in-Chief
Leonard and Madlyn Abramson Endowed Chair in
Pediatrics
Children’s Hospital of Philadelphia
Philadelphia, Pennsylvania
NATHAN J. BLUM, MD ROBERT C. TASKER, MBBS, MD
William H. Bennett Professor of Pediatrics Professor of Neurology
University of Pennsylvania Perelman School of Medicine Professor of Anesthesia
Chief, Division of Developmental and Behavioral Pediatrics Harvard Medical School
Children’s Hospital of Philadelphia Senior Associate, Critical Care Medicine
Philadelphia, Pennsylvania Director, Pediatric NeuroCritical Care Program
Boston Children’s Hospital
SAMIR S. SHAH, MD, MSCE Boston, Massachusetts
Professor of Pediatrics
KAREN M. WILSON, MD, MPH
University of Cincinnati College of Medicine
Director, Division of Hospital Medicine Professor of Pediatrics
Chief Metrics Officer Debra and Leon Black Division Chief of General Pediatrics
James M. Ewell Endowed Chair Vice-Chair for Clinical and Translational Research
Cincinnati Children’s Hospital Medical Center Kravis Children’s Hospital at the Icahn School of Medicine at
Cincinnati, Ohio Mount Sinai
New York, New York
Editor Emeritus
RICHARD E. BEHRMAN, MD
Nonprofit Healthcare and Educational
Consultants to Medical Institutions
Santa Barbara, California
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NELSON TEXTBOOK OF PEDIATRICS, TWENTY-FIRST EDITION ISBN: 978-0-323-52950-1
IE ISBN: 978-0-323-56890-6
Copyright © 2020 Elsevier Inc.
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Previous editions copyrighted 2016, 2011, 2007, 2004, 2000, 1996, 1992, 1987, 1983, 1979, 1975, 1969,
1964, 1959
Notices
Knowledge and best practice in this field are constantly changing. As new research and experience
broaden our understanding, changes in research methods, professional practices, or medical treatment
may become necessary. Practitioners and researchers must always rely on their own experience and
knowledge in evaluating and using any information, methods, compounds, or experiments described
herein. In using such information or methods they should be mindful of their own safety and the safety
of others, including parties for whom they have a professional responsibility. With respect to any drug or
pharmaceutical products identified, readers are advised to check the most current information provided
(i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the
recommended dose or formula, the method and duration of administration, and contraindications. It is
the responsibility of practitioners, relying on their own experience and knowledge of their patients, to
make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all
appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the authors,
contributors, or editors, assume any liability for any injury and/or damage to persons or property as a
matter of products liability, negligence or otherwise, or from any use or operation of any methods,
products, instructions, or ideas contained in the material herein. The Publisher
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To the Child’s Physician who through their expressed confidence in past editions of this book
have provided the stimulus for this revision. May we continue to be a resource of helpful
information for clinicians who care for all of our children.
R.M. Kliegman
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Contributors
Nadia Y. Abidi, MD John J. Aiken, MD, FACS, FAAP Kelly K. Anthony, PhD, PLLC
Resident Physician Professor of Surgery Assistant Professor
Department of Dermatology Division of Pediatric General and Thoracic Department of Psychiatry and Behavioral
University of Missouri School of Medicine Surgery Sciences
Columbia, Missouri Medical College of Wisconsin Duke University Medical Center
Cutaneous Defects The Children’s Hospital of Wisconsin Durham, North Carolina
Ectodermal Dysplasias Milwaukee, Wisconsin Musculoskeletal Pain Syndromes
Acute Appendicitis
Mark J. Abzug, MD Inguinal Hernias Alia Y. Antoon, MD, DCH
Professor of Pediatrics Epigastric Hernia Senior Fellow
Vice Chair for Academic Affairs Incisional Hernia American Academy of Pediatrics
University of Colorado School of Medicine Honorary Pediatrician
Section of Pediatric Infectious Diseases Cezmi A. Akdis, MD MassGeneral Hospital for Children
Children’s Hospital Colorado Professor of Immunology Boston, Massachusetts
Aurora, Colorado Swiss Institute of Allergy and Asthma Research Burn Injuries
Nonpolio Enteroviruses Christine Kühne Center for Allergy Research and Cold Injuries
Education
David R. Adams, MD, PhD Davos, Switzerland; Susan D. Apkon, MD
Associate Investigator, Undiagnosed Diseases Medical Faculty, University of Zurich Professor
Program Zurich, Switzerland Department of Physical Medicine and
Senior Staff Clinician Allergy and the Immunologic Basis of Atopic Rehabilitation
National Human Genome Research Institute Disease University of Colorado
National Institutes of Health Denver, Colorado;
Bethesda, Maryland Evaline A. Alessandrini, MD, MSCE Chief, Pediatric Rehabilitation
Genetic Approaches to Rare and Undiagnosed Professor of Clinical Pediatrics Children’s Hospital Colorado
Diseases University of Cincinnati College of Medicine Aurora, Colorado
Division of Emergency Medicine Ambulation Assistance
Nicholas S. Adams, MD Director, Quality Scholars Program in Health
Plastic Surgery Resident Care Transformation Stacy P. Ardoin, MD, MHS
Spectrum Health Hospitals Cincinnati Children’s Hospital Medical Center Associate Professor of Clinical Medicine
Michigan State University Cincinnati, Ohio Division of Adult and Pediatric Rheumatology
Grand Rapids, Michigan Outcomes and Risk Adjustment of Emergency The Ohio State University Wexner Medical
Deformational Plagiocephaly Medical Services Center
Nationwide Children’s Hospital
Stewart L. Adelson, MD Michael A. Alexander, MD Columbus, Ohio
Assistant Clinical Professor Professor of Pediatrics and Rehabilitation Systemic Lupus Erythematosus
Department of Psychiatry Medicine Vasculitis Syndromes
Columbia University College of Physicians and Thomas Jefferson Medical College
Surgeons Philadelphia, Pennsylvania; Alexandre Arkader, MD
Adjunct Clinical Assistant Professor Emeritus Medical Staff Attending Orthopaedic Surgeon
Weill Cornell Medical College of Cornell Nemours Alfred I. duPont Hospital for Children Children’s Hospital of Philadelphia
University Wilmington, Delaware Philadelphia, Pennsylvania
New York, New York Evaluation of the Child for Rehabilitative Services Common Fractures
Gay, Lesbian, and Bisexual Adolescents
Omar Ali, MD Thaís Armangué, MD, PhD
Shawn K. Ahlfeld, MD Pediatric Endocrinology Pediatric Neurologist
Assistant Professor of Pediatrics Valley Children’s Hospital Neuroimmunology Program
University of Cincinnati College of Medicine Madera, California IDIBAPS—Hospital Clinic–Hospital Sant Joan de
Attending Neonatologist, Perinatal Institute Hyperpituitarism, Tall Stature, and Overgrowth Déu (Barcelona)
Cincinnati Children’s Hospital Medical Center Syndromes University of Barcelona
Cincinnati, Ohio Hypofunction of the Testes Barcelona, Spain
Respiratory Tract Disorders Pseudoprecocity Resulting from Tumors of Autoimmune Encephalitis
the Testes
Osman Z. Ahmad, MD Carola A.S. Arndt, MD
Gynecomastia
Fellow in Pediatric Gastroenterology Professor of Pediatrics
University of Alabama at Birmingham School of Karl E. Anderson, MD, FACP Department of Pediatrics and Adolescent
Medicine Professor of Preventive Medicine and Community Medicine
Birmingham, Alabama Health and Internal Medicine Division of Pediatric Hematology-Oncology
Clostridium difficile Infection Director, Porphyria Laboratory and Center Mayo Clinic
University of Texas Medical Branch Rochester, Minnesota
Galveston, Texas Soft Tissue Sarcomas
The Porphyrias
Paul L. Aronson, MD
Associate Professor of Pediatrics and Emergency
Medicine
Yale School of Medicine
New Haven, Connecticut
Fever in the Older Child
vii
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viii Contributors
David M. Asher, MD Marilyn C. Augustyn, MD Keith D. Baldwin, MD, MSPT,
Supervisory Medical Officer and Chief Professor of Pediatrics MPH
Laboratory of Bacterial and Transmissible Boston University School of Medicine Assistant Professor
Spongiform Encephalopathy Agents Boston Medical Center Department of Orthopaedic Surgery
Division of Emerging and Transfusion- Boston, Massachusetts University of Pennsylvania Perelman School of
Transmitted Diseases Impact of Violence on Children Medicine
US Food and Drug Administration Attending Physician
Silver Spring, Maryland Yaron Avitzur, MD Neuromuscular Orthopaedics and Orthopaedic
Transmissible Spongiform Encephalopathies Associate Professor Trauma
Department of Pediatrics Children’s Hospital of Philadelphia
Ann Ashworth, PhD, Hon FRCPCH University of Toronto Faculty of Medicine Philadelphia, Pennsylvania
Professor Emeritus Division of Gastroenterology, Hepatology, Growth and Development
Department of Population Health and Nutrition Evaluation of the Child
Nutrition Group The Hospital for Sick Children Torsional and Angular Deformities
London School of Hygiene and Tropical Medicine Toronto, Canada Common Fractures
London, United Kingdom Short Bowel Syndrome
Nutrition, Food Security, and Health Christina Bales, MD
Carlos A. Bacino, MD Associate Professor of Clinical Pediatrics
Amit Assa, MD Professor and Vice Chair of Clinical Affairs University of Pennsylvania Perelman School of
Associate Professor of Pediatrics Department of Molecular and Human Genetics Medicine
Sackler Faculty of Medicine Baylor College of Medicine Medical Director, Intestinal Rehabilitation
Tel Aviv University Director, Pediatrics Genetics Clinic Program
Tel Aviv, Israel; Texas Children’s Hospital Division of Gastroenterology, Hepatology,
Head, IBD Unit Houston, Texas and Nutrition
Institute of Gastroenterology, Nutrition, and Liver Cytogenetics Children’s Hospital of Philadelphia
Diseases Philadelphia, Pennsylvania
Schneider Children’s Medical Center Zinzi D. Bailey, ScD, MSPH Intestinal Atresia, Stenosis, and Malrotation
Petah Tikva, Israel Assistant Scientist
Immunodeficiency Disorders University of Miami Miller School of Medicine William F. Balistreri, MD
Miami, Florida Medical Director Emeritus, Pediatric Liver Care
Barbara L. Asselin, MD Racism and Child Health Center
Professor of Pediatrics and Oncology Division of Pediatric Gastroenterology,
Department of Pediatrics Binod Balakrishnan, MBBS Hepatology, and Nutrition
University of Rochester School of Medicine and Assistant Professor Cincinnati Children’s Hospital Medical Center
Dentistry Department of Pediatrics Cincinnati, Ohio
Golisano Children’s Hospital and Wilmot Cancer Medical College of Wisconsin Morphogenesis of the Liver and Biliary System
Institute Division of Pediatric Critical Care Manifestations of Liver Disease
Rochester, New York Children’s Hospital of Wisconsin Cholestasis
Epidemiology of Childhood and Adolescent Cancer Milwaukee, Wisconsin Metabolic Diseases of the Liver
Brain Death Viral Hepatitis
Christina M. Astley, MD, ScD
Liver Disease Associated with Systemic Disorders
Instructor in Pediatrics Frances B. Balamuth, MD, PhD, Mitochondrial Hepatopathies
Harvard Medical School MSCE
Attending Physician Assistant Professor of Pediatrics Allison Ballantine, MD, MEd
Division of Endocrinology University of Pennsylvania Perelman School of Associate Professor of Clinical Pediatrics
Boston Children’s Hospital Medicine University of Pennsylvania Perelman School of
Boston, Massachusetts Associate Director of Research Medicine
Autoimmune Polyglandular Syndromes Division of Emergency Medicine Co-Director Med Ed Program, Graduate School
Co-Director, Pediatric Sepsis Program of Education
Joann L. Ater, MD Children’s Hospital of Philadelphia Section Chief, Inpatient Services
Professor Philadelphia, Pennsylvania Division of General Pediatrics
Department of Pediatrics Patient Care Triage of the Acutely Ill Child Children’s Hospital of Philadelphia
University of Texas MD Anderson Cancer Center Philadelphia, Pennsylvania
Houston, Texas Robert N. Baldassano, MD Malnutrition
Brain Tumors in Childhood Colman Family Chair in Pediatric Inflammatory
Neuroblastoma Bowel Disease and Professor of Pediatrics Robert S. Baltimore, MD
University of Pennsylvania Perelman School of Professor of Pediatrics and Epidemiology
Norrell Atkinson, MD, FAAP Medicine Clinical Professor of Nursing
Assistant Professor of Pediatrics Director, Center for Pediatric Inflammatory Professor of Pediatrics and Epidemiology
Drexel University College of Medicine Bowel Disease Clinical Professor of Nursing
Child Protection Program Children’s Hospital of Philadelphia Yale School of Medicine
St. Christopher’s Hospital for Children Philadelphia, Pennsylvania Associate Director of Hospital Epidemiology
Philadelphia, Pennsylvania Inflammatory Bowel Disease (for Pediatrics)
Adolescent Sexual Assault Eosinophilic Gastroenteritis Yale–New Haven Hospital
New Haven, Connecticut
Erika U. Augustine, MD
Listeria monocytogenes
Associate Professor of Neurology and Pediatrics
Pseudomonas, Burkholderia, and
Associate Director, Center for Health +
Stenotrophomonas
Technology
Infective Endocarditis
University of Rochester Medical Center
Rochester, New York Manisha Balwani, MBBS, MS
Dystonia Associate Professor of Medicine and Genetics and
Genomic Sciences
Kravis Children’s Hospital at the Icahn School of
Medicine at Mount Sinai
New York, New York
The Porphyrias
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Contributors ix
Vaneeta Bamba, MD Christian P. Bauerfeld, MD Daniel Bernstein, MD
Associate Professor of Clinical Pediatrics Assistant Professor of Pediatrics Alfred Woodley Salter and Mabel G. Salter
University of Pennsylvania Perelman School of Wayne State University School of Medicine Endowed Professor in Pediatrics
Medicine Division of Pediatric Critical Care Medicine Associate Dean for Curriculum and Scholarship
Medical Director, Diagnostic and Research Children’s Hospital of Michigan Stanford University School of Medicine
Growth Center Detroit, Michigan Palo Alto, California
Children’s Hospital of Philadelphia Mechanical Ventilation Cardiac Development
Philadelphia, Pennsylvania The Fetal to Neonatal Circulatory Transition
Assessment of Growth Rebecca A. Baum, MD History and Physical Examination in Cardiac
Clinical Associate Professor of Pediatrics Evaluation
Brenda L. Banwell, MD The Ohio State University College of Medicine Laboratory Cardiac Evaluation
Professor of Neurology Chief, Developmental Behavioral Pediatrics Epidemiology and Genetic Basis of Congenital
Grace R. Loeb Endowed Chair in Neurosciences Nationwide Children’s Hospital Heart Disease
University of Pennsylvania Perelman School of Columbus, Ohio Evaluation and Screening of the Infant or Child
Medicine Positive Parenting and Support with Congenital Heart Disease
Chief, Division of Neurology Acyanotic Congenital Heart Disease: Left-to-Right
Director, Pediatric Multiple Sclerosis Clinic Michael J. Bell, MD Shunt Lesions
Children’s Hospital of Philadelphia Professor, Pediatrics and Critical Care Medicine Acyanotic Congenital Heart Disease: The
Philadelphia, Pennsylvania Chief, Critical Care Medicine Obstructive Lesions
Central Nervous System Vasculitis Children’s National Medical Center Acyanotic Congenital Heart Disease: Regurgitant
The George Washington University School of Lesions
Sarah F. Barclay, PhD Medicine Cyanotic Congenital Heart Disease: Evaluation of
Department of Medical Genetics Washington, DC the Critically Ill Neonate with Cyanosis and
Cumming School of Medicine at University of Neurologic Emergencies and Stabilization Respiratory Distress
Calgary Cyanotic Congenital Heart Lesions: Lesions
Alberta Children’s Hospital Research Institute Nicole R. Bender, MD Associated with Decreased Pulmonary Blood
Calgary, Alberta, Canada Resident Physician Flow
Rapid-Onset Obesity with Hypothalamic Department of Dermatology Cyanotic Congenital Heart Disease: Lesions
Dysfunction, Hypoventilation, and Autonomic Medical College of Wisconsin Associated with Increased Pulmonary Blood
Dysregulation (ROHHAD) Milwaukee, Wisconsin Flow
Morphology of the Skin Other Congenital Heart and Vascular
Maria E. Barnes-Davis, MD, PhD Dermatologic Evaluation of the Patient Malformations
Assistant Professor of Pediatrics Eczematous Disorders Pulmonary Hypertension
University of Cincinnati College of Medicine Photosensitivity General Principles of Treatment of Congenital
Attending Neonatologist Diseases of the Epidermis Heart Disease
Division of Neonatology and Pulmonary Biology Diseases of the Blood Vessels (Aneurysms and
Cincinnati Children’s Hospital Medical Center Daniel K. Benjamin Jr, MD, PhD, Fistulas)
Cincinnati, Ohio MPH
The High-Risk Infant Kiser-Arena Professor of Pediatrics Henry H. Bernstein, DO, MHCM,
Duke Clinical Research Institute FAAP
Karyl S. Barron, MD Duke University Medical Center Professor of Pediatrics
Deputy Director Durham, North Carolina Zucker School of Medicine at Hofstra/Northwell
Division of Intramural Research Principles of Antifungal Therapy Cohen Children’s Medical Center of New York
National Institute of Allergy and Infectious Candida New Hyde Park, New York
Diseases Immunization Practices
National Institutes of Health Michael J. Bennett, PhD, FRCPath,
Bethesda, Maryland FACB Diana X. Bharucha-Goebel, MD
Amyloidosis Professor of Pathology and Laboratory Medicine Assistant Professor, Neurology and Pediatrics
University of Pennsylvania Perelman School of Children’s National Medical Center
Donald Basel, MBBCh Medicine Washington, DC;
Associate Professor of Pediatrics and Genetics Director, Michael J. Palmieri Metabolic Disease Clinical Research Collaborator
Chief, Medical Genetics Division Laboratory National Institutes of Health/NINDS
Medical College of Wisconsin Children’s Hospital of Philadelphia Neurogenetics Branch/NNDCS
Milwaukee, Wisconsin Philadelphia, Pennsylvania Bethesda, Maryland
Ehlers-Danlos Syndrome Disorders of Mitochondrial Fatty Acid β-Oxidation Muscular Dystrophies
Myasthenia Gravis
Dorsey M. Bass, MD
Giant Axonal Neuropathy
Associate Professor of Pediatrics
Stanford University School of Medicine Holly M. Biggs, MD, MPH
Division of Pediatric Gastroenterology Medical Epidemiologist
Lucile Salter Packard Children’s Hospital Respiratory Viruses Branch, Division of Viral
Palo Alto, California Diseases
Rotaviruses, Caliciviruses, and Astroviruses National Center for Immunization and
Respiratory Diseases
Mary T. Bassett, MD, MPH
Centers for Disease Control and Prevention
FXB Professor of the Practice of Public Health
Atlanta, Georgia
and Human Rights
Parainfluenza Viruses
Harvard T.H. Chan School of Public Health
Boston, Massachusetts Samra S. Blanchard, MD
Racism and Child Health Associate Professor
Department of Pediatrics
University of Maryland School of Medicine
Baltimore, Maryland
Peptic Ulcer Disease in Children
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x Contributors
Joshua A. Blatter, MD, MPH Daniel J. Bonthius, MD, PhD Amanda M. Brandow, DO, MS
Assistant Professor of Pediatrics, Allergy, Professor of Pediatrics and Neurology Associate Professor
Immunology, and Pulmonary Medicine University of Iowa Carver College of Medicine Department of Pediatrics
Researcher, Patient Oriented Research Unit Iowa City, Iowa Division of Pediatric Hematology/Oncology
Washington University School of Medicine in Lymphocytic Choriomeningitis Virus Medical College of Wisconsin
St. Louis Milwaukee, Wisconsin
St. Louis, Missouri Brett J. Bordini, MD, FAAP Enzymatic Defects
Congenital Disorders of the Lung Associate Professor of Pediatrics Hemolytic Anemias Resulting from Extracellular
Division of Hospital Medicine Factors—Immune Hemolytic Anemias
Archie Bleyer, MD, FRCP (Glasg) Nelson Service for Undiagnosed and Rare Hemolytic Anemias Secondary to Other
Clinical Research Professor Diseases Extracellular Factors
Knight Cancer Center Director, Medical Spanish Curriculum Polycythemia
Oregon Health & Science University Medical College of Wisconsin Nonclonal Polycythemia
Chair, Institutional Review Board for St. Charles Milwaukee, Wisconsin
Health System Plastic Bronchitis David T. Breault, MD, PhD
Portland, Oregon; Associate Professor of Pediatrics
Professor of Pediatrics Kristopher R. Bosse, MD Harvard Medical School
University of Texas MD Anderson Cancer Center Instructor in Pediatrics Division of Endocrinology
Houston, Texas University of Pennsylvania Perelman School of Boston Children’s Hospital
Principles of Cancer Treatment Medicine Boston, Massachusetts
The Leukemias Attending Physician Diabetes Insipidus
Division of Oncology Other Abnormalities of Arginine Vasopressin
Nathan J. Blum, MD Children’s Hospital of Philadelphia Metabolism and Action
William H. Bennett Professor of Pediatrics Philadelphia, Pennsylvania
University of Pennsylvania Perelman School of Molecular and Cellular Biology of Cancer Cora Collette Breuner, MD, MPH
Medicine Professor of Pediatrics
Chief, Division of Developmental and Behavioral Bret L. Bostwick, MD Adjunct Professor of Orthopedics and Sports
Pediatrics Assistant Professor Medicine
Children’s Hospital of Philadelphia Department of Molecular and Human Genetics University of Washington School of Medicine
Philadelphia, Pennsylvania Baylor College of Medicine Division of Adolescent Medicine
Houston, Texas Department of Orthopedics and Sports Medicine
Steven R. Boas, MD, FAAP, Genetics of Common Disorders Seattle Children’s Hospital
FACSM Seattle, Washington
Director, The Cystic Fibrosis Center of Chicago Kenneth M. Boyer, MD Substance Abuse
President and CEO, The Cystic Fibrosis Institute Professor and Woman’s Board Chair, Emeritus Adolescent Pregnancy
Glenview, Illinois; Department of Pediatrics
Clinical Professor of Pediatrics Rush University Medical Center Carolyn Bridgemohan, MD
Northwestern University Feinberg School of Chicago, Illinois Associate Professor of Pediatrics
Medicine Toxoplasmosis (Toxoplasma gondii) Harvard Medical School
Chicago, Illinois Co-Director Autism Spectrum Center
Jennifer M. Brady, MD
Emphysema and Overinflation Division of Developmental Medicine
α1-Antitrypsin Deficiency and Emphysema Assistant Professor of Pediatrics Boston Children’s Hospital
Other Distal Airway Diseases University of Cincinnati College of Medicine Boston, Massachusetts
Skeletal Diseases Influencing Pulmonary Function Perinatal Institute Autism Spectrum Disorder
Division of Neonatology
Walter O. Bockting, PhD Cincinnati Children’s Hospital Medical Center William J. Britt, MD
Professor of Medical Psychology (in Psychiatry Cincinnati, Ohio Charles A. Alford Professor of Pediatrics
and Nursing) The High-Risk Infant Professor of Microbiology and Neurobiology
Research Scientist, New York State Psychiatric Transport of the Critically Ill Newborn University of Alabama Birmingham School of
Institute Neonatal Resuscitation and Delivery Room Medicine
Division of Gender, Sexuality, and Health Emergencies Division of Pediatric Infectious Diseases
Department of Psychiatry Children’s of Alabama
Patrick W. Brady, MD, MSc
Columbia University Vagelos College of Birmingham, Alabama
Physicians and Surgeons Associate Professor of Pediatrics Cytomegalovirus
New York, New York University of Cincinnati College of Medicine
Gender and Sexual Identity Attending Physician, Division of Hospital Laura Brower, MD
Transgender Care Medicine Assistant Professor of Pediatrics
Cincinnati Children’s Hospital Medical Center University of Cincinnati College of Medicine
Mark Boguniewicz, MD Cincinnati, Ohio Division of Hospital Medicine
Professor of Pediatrics Safety in Healthcare for Children Cincinnati Children’s Hospital Medical Center
Division of Allergy-Immunology Cincinnati, Ohio
Rebecca C. Brady, MD
Department of Pediatrics Fever Without a Focus in the Neonate and Young
University of Colorado School of Medicine Professor of Pediatrics Infant
National Jewish Health University of Cincinnati College of Medicine
Denver, Colorado Cincinnati Children’s Hospital Medical Center Rebeccah L. Brown, MD
Ocular Allergies Cincinnati, Ohio Professor of Clinical Surgery and Pediatrics
Congenital and Perinatal Infections University of Cincinnati College of Medicine
Michael J. Boivin, PhD, MPH Coccidioidomycosis (Coccidioides Species) Co-Director of Pectus Program
Professor of Psychiatry and of Neurology and Associate Director of Trauma Services
Samuel L. Brady, MS, PhD
Ophthalmology Cincinnati Children’s Hospital Medical Center
Michigan State University College of Osteopathic Clinical Medical Physicist Cincinnati, Ohio
Medicine Cincinnati Children’s Hospital Meconium Ileus, Peritonitis, and Intestinal
East Lansing, Michigan Associate Professor of Radiology Obstruction
Nodding Syndrome University of Cincinnati Necrotizing Enterocolitis
Cincinnati, Ohio
Biologic Effects of Ionizing Radiation on Children
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