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Natural Products Pharmacology and Phytochemicals for Health Care: Methods and Principles in Medicinal Chemistry PDF

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NATURAL PRODUCTS PHARMACOLOGY AND PHYTOCHEMICALS FOR HEALTH CARE Methods and Principles in Medicinal Chemistry NATURAL PRODUCTS PHARMACOLOGY AND PHYTOCHEMICALS FOR HEALTH CARE Methods and Principles in Medicinal Chemistry Edited by Debarshi Kar Mahapatra, PhD Cristóbal Noé Aguilar, PhD A. K. Haghi, PhD First edition published 2021 Apple Academic Press Inc. CRC Press 1265 Goldenrod Circle, NE, 6000 Broken Sound Parkway NW, Palm Bay, FL 32905 USA Suite 300, Boca Raton, FL 33487-2742 USA 4164 Lakeshore Road, Burlington, 2 Park Square, Milton Park, ON, L7L 1A4 Canada Abingdon, Oxon, OX14 4RN UK © 2021 Apple Academic Press, Inc. Apple Academic Press exclusively co-publishes with CRC Press, an imprint of Taylor & Francis Group, LLC Reasonable efforts have been made to publish reliable data and information, but the authors, editors, and publisher cannot assume responsibility for the validity of all materials or the consequences of their use. The authors, editors, and publishers have attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowledged, please write and let us know so we may rectify in any future reprint. Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, access www.copyright.com or contact the Copyright Clearance Center, Inc. (CCC), 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. For works that are not available on CCC please contact [email protected] Trademark notice: Product or corporate names may be trademarks or registered trademarks and are used only for identification and explanation without intent to infringe. Library and Archives Canada Cataloguing in Publication Title: Natural products pharmacology and phytochemicals for health care : methods and principles in medicinal chemistry / edited by Debarshi Kar Mahapatra, PhD, Cristóbal Noé Aguilar, PhD, A.K. Haghi, PhD. Names: Mahapatra, Debarshi Kar, editor. | Aguilar, Cristóbal Noé, editor. | Haghi, A. K., editor. Description: Includes bibliographical references and index. Identifiers: Canadiana (print) 20200363433 | Canadiana (ebook) 20200363506 | ISBN 9781771889018 (hardcover) | ISBN 9781003057932 (ebook) Subjects: LCSH: Biological products. | LCSH: Drug development. | LCSH: Pharmaceutical chemistry. Classification: LCC RM301.25 .N38 2021 | DDC 615.1/9—dc23 Library of Congress Cataloging-in-Publication Data Names: Mahapatra, Debarshi Kar, editor. | Aguilar, Cristóbal Noé, editor. | Haghi, A. K., editor. Title: Natural products pharmacology and phytochemicals for health care : methods and principles in medicinal chemistry / edited by Debarshi Kar Mahapatra, Cristóbal Noé Aguilar, A.K. Haghi. Description: First edition. | Palm Bay, FL : Apple Academic Press, 2021. | Includes bibliographical references and index. | Summary: “Medicinal chemistry and pharmacology are closely associated fields, and the use of natural products for their medicinal properties is ever-growing. The study of drugs from natural products and their effects on the living body are explored in this volume. The book looks into the research, discovery and characterization of the chemicals that exhibit biological effects. Providing an informative compilation of research, valuable case studies, and review of existing literature in the area, the book focuses on the ethnobotanical uses of natural products and phytochemicals for health care, including applications for diabeties, ulcers, wound healing, managing chronic alcoholism, hemorrhoidal treatment, cancer mitigation, pain management, immunotherapy, and more. The book briefly describes bioinformatics, artificial intelligence, machine learning, innovations, and societal applications. Natural Products Pharmacology and Phytochemicals for Health Care: Methods and Principles in Medicinal Chemistry provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. This volume provides new coverage of some of the latest technologies and approaches in drug discovery”-- Provided by publisher. Identifiers: LCCN 2020046631 (print) | LCCN 2020046632 (ebook) | ISBN 9781771889018 (hardcover) | ISBN 9781003057932 (ebook) Subjects: MESH: Biological Products | Drug Discovery Classification: LCC RM301.25 (print) | LCC RM301.25 (ebook) | NLM QV 241 | DDC 615.1/9--dc23 LC record available at https://lccn.loc.gov/2020046631 LC ebook record available at https://lccn.loc.gov/2020046632 ISBN: 978-1-77188-901-8 (hbk) ISBN: 978-1-00305-793-2 (ebk) About the Editors Debarshi Kar Mahapatra, PhD Assistant Professor, Department of Pharmaceutical Chemistry, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India Debarshi Kar Mahapatra, PhD, is currently an Assistant Professor in the Department of Pharmaceutical Chemistry at Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maha- rashtra, India. He was formerly an Assistant Professor in the Department of Pharmaceutical Chemistry, Kamla Nehru College of Pharmacy, RTM Nagpur University, Nagpur, India. He has taught medicinal and computational chem- istry at both the undergraduate and postgraduate levels and has mentored students in their various research projects. His area of interest includes computer-assisted rational designing and synthesis of low molecular weight ligands against druggable targets, drug delivery systems, and optimization of unconventional formulations. He has published research, book chapters, reviews, and case studies in various reputed journals and has presented his work at several international platforms, for which he has received several awards by a number of bodies. He has also authored the book titled Drug Design. Presently, he is serving as a reviewer and editorial board member for several journals of international repute. He is a member of a number of professional and scientific societies, such as the International Society for Infectious Diseases (ISID), the International Science Congress Association (ISCA), and ISEI. Cristóbal Noé Aguilar, PhD Director of Research and Postgraduate Programs at Universidad Autonoma de Coahuila, Mexico Cristóbal Noé Aguilar, PhD, is a Director of Research and Postgraduate Programs at Universidad Autonoma de Coahuila, Mexico. Dr. Aguilar has published more than 160 papers in indexed journals, more than 40 articles in Mexican journals, and 250 contributions in scientific meetings. He has vi About the Editors also published many book chapters, several Mexican books, four editions of international books, and more. Prof. Aguilar is a member of level III of S.N.I. (National System of Researchers of Mexico). He has been awarded several prizes and awards; the most important are the National Prize of Research 2010 from the Mexican Academy of Sciences; the Prize “Carlos Casas Campillo 2008” from the Mexican Society of Biotechnology and Bioengineering; National Prize AgroBio–2005 and the Mexican Prize in Food Science and Technology. Dr. Aguilar is a member of the Mexican Academy of Science, the International Bioprocessing Association, Mexican Academy of Sciences, Mexican Society for Biotechnology and Bioengineering, and the Mexican Association for Food Science and Biotechnology. He has developed more than 21 research projects, including six international exchange projects. He has been an advisor for PhD, MSc, and BSc theses. Dr. Aguilar earned his chemist designation from the School of Chemistry at the Universidad Autónoma de Coahuila, México. He attended the MSc Program in Food Science and Biotechnology that was held at the Universidad Autónoma de Chihuahua, México. His PhD in Fermentation Biotechnology was awarded by the Universidad Autónoma Metropolitana, Mexico. A. K. Haghi, PhD Professor Emeritus of Engineering Sciences, Former Editor-in-Chief, International Journal of Chemoinformatics and Chemical Engineering and Polymers Research Journal; Member, Canadian Research and Development Center of Sciences and Culture A. K. Haghi, PhD, is the author and editor of over 200 books, as well as over 1000 published papers in various journals and conference proceedings. Dr. Haghi has received several grants, consulted for a number of major corpora- tions, and is a frequent speaker to national and international audiences. Since 1983, he served as a professor at several universities. He is former Editor- in-Chief of the International Journal of Chemoinformatics and Chemical Engineering and Polymers Research Journal and is on the editorial boards of many international journals. He is also a member of the Canadian Research and Development Center of Sciences and Cultures (CRDCSC), Montreal, Quebec, Canada. Contents Contributors ........................................................................................................... ix Abbreviations .......................................................................................................... xi Preface ................................................................................................................. xvii 1. A Short Overview on Anti-Diabetic Natural Products: Reviewing the Herbotherapeutic Potentials ................................................................... 1 Mojabir Hussen Ansari and Debarshi Kar Mahapatra 2. Exploring the Hidden Ethnobotanical Treasures for Treating or Managing Chronic Alcoholism ................................................................... 23 Sameer A. Hedaoo and Debarshi Kar Mahapatra 3. Reviewing the Aphrodisiac Activity of Lepedium meyenii Plant in Modern Contexts .......................................................................................... 41 Shilpa S. Borkar, Debarshi Kar Mahapatra, and Seema Usare 4. Matter, Plasma, Quasi Two-Dimensional Au Film, Drug Products Quality, and Circular Economy .................................................................. 55 Francisco Torrens and Gloria Castellano 5. Deep Insights into the Privileged Herbotherapeutic Inventory for Hemorrhoidal Treatment ............................................................................ 73 Paras Kothari, Ankita Soni, and Debarshi Kar Mahapatra 6. Precision, Immunotherapy, Immuno Oncology, and Research in Cancer ....................................................................................................... 93 Francisco Torrens and Gloria Castellano 7. Oxidative Stress-Protective/Anti-Melanogenic Effects of Loliolide ...... 107 Francisco Torrens and Gloria Castellano 8. Recent Advancements in the Pharmacotherapeutic Perspectives of Some Chalcone Scaffolds Containing Natural Compounds as Potential Anti-Virals ...................................................................................117 Debarshi Kar Mahapatra, Sanjay Kumar Bharti, and Vivek Asati 9. Ethnoscience, Alternative Medicine, Inflammation, and Pain Models ................................................................................................ 133 Francisco Torrens and Gloria Castellano viii Contents 10. Orange Fruit and Bioplastics with Limonene and No Bisphenol A....... 147 Francisco Torrens and Gloria Castellano 11. Innovation and Challenges in the Development of Functional and Medicinal Beverages .................................................................................. 157 Dayang Norulfairuz Abang Zaidel, Ida Idayu Muhamad, Zanariah Hashim, Yanti Maslina Mohd. Jusoh, and Eraricar Salleh 12. Oestradiol, Aging Theory, Women/LGBT Difficulties and Motivation ........................................................................................... 219 Francisco Torrens and Gloria Castellano 13. Women, Men, Health, Big Data, Taste to Classify and Innovation ....... 237 Francisco Torrens and Gloria Castellano Index .................................................................................................................... 247 Contributors Mojabir Hussen Ansari Gurunanak College of Pharmacy, Dixit Nagar, Nagpur, 440026, Maharashtra, India Vivek Asati Department of Pharmaceutical Chemistry, NRI Institute of Pharmacy, Bhopal, Madhya Pradesh, 462021, India Sanjay Kumar Bharti Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, Chhattisgarh, 495009, India Shilpa S. Borkar Department of Pharmacology, Kamla Nehru College of Pharmacy, Nagpur – 441108, Maharashtra, India Gloria Castellano Departamento de Ciencias Experimentales y Matemáticas, Facultad de Veterinaria y Ciencias Experimentales, Universidad Católica de Valencia San Vicente Mártir, Guillem de Castro-94, E-46001 València, Spain Zanariah Hashim Food and Biomaterial Engineering Research Group, School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia Sameer A. Hedaoo Department of Pharmaceutical Chemistry, Gurunanak College of Pharmacy and Technical Institute, Nagpur – 440026, Maharashtra, India Yanti Maslina Mohd Jusoh Food and Biomaterial Engineering Research Group, School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia Paras Kothari Department of Pharmaceutics, Gurunanak College of Pharmacy and Technical Institute, Nagpur – 440026, Maharashtra, India Debarshi Kar Mahapatra Assistant Professor, Department of Pharmaceutical Chemistry, Dadasaheb Balpande College of Pharmacy, Nagpur, 440037, Maharashtra, India, E-mail: [email protected] Ida Idayu Muhamad Food and Biomaterial Engineering Research Group, School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia Eraricar Salleh Food and Biomaterial Engineering Research Group, School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia Ankita Soni Department of Pharmaceutics, Gurunanak College of Pharmacy and Technical Institute, Nagpur – 440026, Maharashtra, India x Contributors Francisco Torrens Institut Universitari de Ciència Molecular, Universitat de València, Edifici d’Instituts de Paterna, P.O. Box 22085, E-46071 València, Spain, E-mail: [email protected] Seema Usare Department of Pharmacology, Kamla Nehru College of Pharmacy, Nagpur – 441108, Maharashtra, India Dayang Norulfairuz Abang Zaidel Food and Biomaterial Engineering Research Group, School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, 81310 Johor Bahru, Malaysia, Tel: +607 5535503; E-mail: [email protected]

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