nashville anaerobenashville 2016 anaerobe 2016

143 Pages·2016·3.45 MB·English

Program & abstract book
2 0 1 6 NASHVILLE
A N A E R O B E JULY 11-14, 2016
2 0 1 6 NASHVILLE
A N A E R O B E JULY 11-14, 2016
The 13th Biennial Congress of the
Anaerobe Society of the Americas
sheraton Nashville
Downtown Hotel
Nashville, tennessee
P & a b
rogram bstract ook
A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6
Contents
Course Directors ii
A2N01AA6EboWuRte ltcOhoem SBPeo acLitEeerotttineessrN JUALYS 1H1ii-ivv1iV4,I L20L1E6
Exhibitors v
Keynote Speaker vi
Lifetime Achievement Award vii
Accreditation viii
Curricular Goals & Objectives viii
Presenters & Faculty ix
Disclosure Information xii
Congress Program xv
Abstract Table of Contents 1
Abstracts 3
Poster Index 237
Author Index 249
the 13th Biennial Congress of the Anaerobe society of the Americas
Sheraton Nashville Downtown Hotel • Nashville, Tennessee
A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6 Welcome Letter A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6
Course DireCtor
David M. Aronoff, M.D.
ASA President
A2N01A6EROBE NJUALYS 1H1-1VV4,Ia L2n0L1dE6erbiNlt aUsnhivviellres,i TtyN M, UedSiAcal Center SsWcoiecelinceottiyms toesf tf torho Aem nA AamreoreuorinBcdae s t2 h(0Ae1 Sw6A,o t)rh.l d eT 1tho3i steh fn obgriauegnmen ibinarl ip nCrAgoe2sNsn0 etg1Aonr6gtEeaesRttsihO ooenBfr s tEc,h ldeiNJni UAaAiLYclSn o1iHa1ga-n1Veu4sr,Ie L2o as0Lb1,nE6 ead n d
organizing Committee
interactions related to the clinical and microbiological aspects of anaerobic
bacteriology. The Congress will explore the role of anaerobes in both health
Emma Allen-Vercoe, Ph.D. Brandi Limbago, Ph.D.
University of Guelph Centers for Disease Control and disease, while addressing both traditional and emerging technologies
Guelph, Canada Atlanta, GA USA for identification and diagnosis.
Karen Carroll, M.D. Leandro Araujo Lobo, Ph.D. AnAeroBe 2016 again illustrates the international interest in the field of
Johns Hopkins University Federal University of Rio de Janeiro
anaerobic bacteriology. 187 abstracts were submitted for presentation,
Baltimore, MD USA Rio de Janeiro, Brazil
representing the work of 624 scientists from more than 38 countries.
Ramyavardhanee Chandrasekaran Jeanne Marrazzo, M.D., M.P.H.
Vanderbilt University ASA Vice President The Keynote Address will be given by Dr. Curtis J. Donskey of Case Western
Nashville, TN USA University of Alabama Reserve University and the Louis Stokes Cleveland VA Medical Center.
Birmingham, AL USA Dr. Donskey will challenge traditional models of Clostridium difficile
Diane M. Citron
R.M. Alden Research Lab Andrew B. Onderdonk, Ph.D. transmission and present new approaches to infection control.
Culver City, CA USA Harvard University
Boston, MA USA The Lifetime Achievement Award will be presented to Dr. Bennett Lorber
Laura M. Cox, Ph.D.
of Temple University. Dr. Lorber is being recognized for his career
Harvard University Elisabeth Nagy, M.D., Ph.D.
contributions to the fields on anaerobic bacteriology and infectious diseases.
Boston, MA USA University of Szeged
Szeged, Hungary
David Fredericks, M.D. We would like to thank the members of the Organizing Committee and
ASA Secretary Carl Erik Nord, M.D. the Session Chairs for their assistance in formulating what promises to
University of Washington Karolinska Institute be another exciting program. We also would like to thank those from
Seattle, WA USA Stockholm, Sweden industry—both patrons and exhibitors listed on page v—for the financial
Dale N. Gerding, M.D. Cynthia L. Sears, M.D. support that makes this Congress possible, as well as grants from the
ASA Past President ASA Past President National Institutes of Health, the European Society of Clinical Microbiology
Hines VA Hospital Johns Hopkins University and Infectious Diseases, Burroughs Welcome Fund, and the Gut Check
Maywood, IL USA Baltimore, MD USA Foundation.
Ellie J.C. Goldstein, M.D. Casey J. Theriot, Ph.D.
ASA Treasurer, Past President In addition, we are grateful for our continued relationship with Anaerobe
North Carolina State University
R.M. Alden Research Lab / UCLA Raleigh, NC Systems for helping organize the Pre-Congress Workshop, Microbiology
Santa Monica, CA USA Educational Services for providing the continuing education accreditation
Yiping Han, Ph.D. Glenn S. Tillotson, Ph.D. for laboratory scientists, and to our Anaerobe journal for sponsorship of the
Cempra Pharmaceuticals
Columbia University Young Investigator’s Competition.
Chapel Hill, NC USA
New York, NY USA
Vincent Young, M.D. Very special thanks goes to Dr. Ronald and Pamela Goldman, who again
Purnima Kumar, D.D.S.
University of Michigan have done an exemplary job in bringing this meeting together.
Ohio State University
Ann Arbor, MI USA
Columbus, OH USA
Lastly, I hope you have an opportunity to explore Nashville, while you are
Ronald J. Goldman, Ph.D. here, and savor what makes it the Music Capital of America.
ASA Executive Director
Los Angeles, CA USA Our hope is that AnAeroBe 2016 serves to foster stimulating discussions, as
well as cultivate personal relationships that continue to invigorate the entire
anaerobe soCiety of the ameriCas field beyond the timeframe of this Congress.
PO Box 452058, Los Angeles, CA 90045 USA
Phone: [phone] Fax: [phone] David M. Aronoff
Web: www.anaerobe.org E-mail: [email protected]
ASA President
©2016 Anaerobe Society of the Americas
iv v
A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6 About the society Patrons & exhibitors A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6
AFobuoAn2udN0te1 Adt6 EhinRe 1OA9Bn92AE,e tNrhJUoAeLY bSA 1eH1n- 1VSa4,Ie oL2r0Lc1oE6ibeet ySociety of the Americas, a non-profit foundation, Aorngaaenriozbaeti oSnosc ifeotyr tohfe tihr eg eAnmereoruicsa ssu gprpatoerftu ollfy t haicsk Acn2oNo0nw1Ag6lEreeRdsgOs.eBs EthNeJU AfLYoS 1lH1l-o1V4w,I L20iL1nE6g
serves as a forum for those interested in anaerobes, anaerobic infections, and
Support for this activity was received in the form of educational grants from:
related matters. The Society aims: (1) to stimulate interest in anaerobes and
to encourage interchange among anaerobists from all disciplines, including u Burroughs Wellcome Fund
medical, dental, veterinary, environmental, and basic sciences; (2) to bring u European Society of Clinical Microbiology and Infectious Diseases
together investigators, clinicians, and laboratory scientists interested in u Gut Check Foundation
anaerobic infections for formal and informal meetings; (3) to review and assess
u National Institute of Health
new advances in the field; (4) to discuss areas of controversy; and (5) to mark
future directions.
Support for this activity from commercial interests include:
There are four levels of membership: Doctoral, Non-Doctoral, Verified Student, PlAtinum PAtronS
and Retired. Details and application form are available on our web site: www.
u Merck
anaerobe.org.
u Sanofi Pasteur
AnAerobe Society PreSidentS Silver PAtronS
This is the 13th biennial Anaerobe Society Congress. u Pfizer
Past Anaerobe Society sponsored programs were:
bronze PAtronS
ANAEROBE 2014 —Chicago, IL USA
u Actelion Pharmaceuticals
ANAEROBE 2012 —San Francisco, CA USA u Anaerobe Journal / Elsevier
u Anaerobe Systems
ANAEROBE 2010 —Philadelphia, PA USA
u ProViotic
ANAEROBE 2008 —Long Beach, CA USA
u Rebiotix
ANAEROBE 2006 —Boise, ID USA u Seres Therapeutics
u Summit Therapeutics
ANAEROBE 2004 —Annapolis, MD USA
u TechLab
ANAEROBE OLYMPIAD 2002 —Park City, UT USA
exhibitorS
2001: AN ANAEROBE ODYSSEY —Los Angeles, CA USA u Advanced Instruments u Key Scientific Products
u Bio K+ International u List Biological Laboratories
ANAEROBE 2000 —Manchester, England
u bioMérieux u Microbiology International
ANAEROBE 1998 —Buenas Aires, Argentina
u Bruker Daltonic u Shel Lab
ANAEROBE 1996 —Chicago, IL USA u Cepheid u Synthetic Biologics
u Coy Laboratory Products u VWR
ANAEROBE 1994 —Los Angeles, CA
ANAEROBE 1992 —Los Angeles, CA
vi vii
A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6 Keynote speaker AchievLeifmeteinmte A ward A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6
A2N01A6EROBE NJUALYS 1H1-1V4,I L20L1E6 curtiS J. donSkey, m.d. bDer.n Lnoetrbt elro srtbuedri,e md z.doo. logy and art history at A2N01A6EROBE NJUALYS 1H1-1V4,I L20L1E6
Dr. Donskey is Professor of Medicine at Case Swarthmore College. He received his M.D. degree
Western Reserve University. He graduated from the University of Pennsylvania School of
from medical school at the Medical College Medicine and completed a residency in internal
of Wisconsin in Milwaukee. He completed medicine and a fellowship in infectious diseases at
his medical residency and chief residency at Temple University Hospital, following which he
Brown University, followed by a fellowship was appointed to the Temple University School of
in Infectious Diseases at Case Western Medicine faculty. In 1988, he was named the first
Reserve University. recipient of the Thomas M. Durant Chair in Medicine
at Temple. He is also a Professor of Microbiology
He has been serving as the Hospital
and Immunology and served as Chief of the Section
Epidemiologist and Chair of the Infection
of Infectious Diseases from 1983-2006.
Control Committee at the Louis Stokes
Cleveland VA Medical Center since 1999. His interest in anaerobic infections emerged during his infectious diseases fel-
lowship. He was responsible for a number of early studies regarding the role of
His research focuses primarily on infection control of healthcare-associated
anaerobic bacteria and their treatment in human respiratory, intra-abdominal, and
pathogens, including Clostridium difficile, methicillin-resistant Staphylococcus
gynecological infections. Other scholarly interests include human listeriosis, an
aureus (MRSA), and multidrug-resistant gram-negative bacilli. His research
area in which he is regarded as an international authority, along with the impact
group has sought to clarify the role of environmental and skin contamination
of societal changes on infectious disease patterns and the relationships between
in the spread of pathogens and worked to develop effective interventions to
infectious agents and chronic illness. He has more than 100 publications to his
prevent transmission from these sources.
credit and has contributed to every edition of Principles and Practice of Infectious
Diseases, the authoritative textbook in the field of infectious diseases.
Dr. Donskey’s research has been funded by the Department of Veterans Affairs,
the Centers for Disease Control and Prevention, and the Agency for Healthcare
He is a Master of the American College of Physicians, a Fellow of the Infectious
Research and Quality. He has published more than 200 peer-reviewed articles
Diseases Society of America, and a Fellow of The College of Physicians of
and several book chapters and review articles. In addition to his research, Dr.
Philadelphia, where he served as President from 2010-2012. He was President of
Donskey has received awards for the teaching of medical students, residents,
the Anaerobe Society of the Americas, 2008-2010.
and fellows.
He has been celebrated repeatedly for his teaching. Among his honors are 12
In his keynote, he will review recent evidence challenging traditional models
Golden Apples, the Temple University Great Teacher Award, the Alexander Fleming
of C. difficile transmission and present new approaches to reduce C. difficile
Lifetime Achievement Award from the Infectious Diseases Society of America,
transmission. These approaches include novel strategies to reduce the burden
and the Jane Desforges Distinguished Teacher Award from the American College of
of spores in the environment and on skin and to prevent transmission by
Physicians. On two occasions, the graduating medical school class dedicated their
asymptomatic carriers. The potential impact of diagnostic testing approaches
yearbook to him In 1996, he received an honorary Doctor of Science degree from
and antimicrobial stewardship on transmission will also be discussed.
Swarthmore College.
In addition, Dr. Lorber is a professional painter—his work can be seen at his web-
site: bennettlorber.blogspot.com—and an accomplished guitarist. He emphasizes the
importance of having a hobby as a doctor. “Doing something that is important to
you, makes you happy, and keeps you sane is just as important as what you do as
a doctor…To best take care of patients, you have to first take care of yourself.”
viii ix
A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6 GoAaclcsr &ed oitbajteicotniv/ es Presenters & Faculty A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6
AmAnmicAreA2oerNib0rci1oaAos6lEb—oeRgp iO2cr0aoBl1v Ea6ids—NpeJUesAtL cYhtS t1heHs1e -11oV 4f3f,Io L2ta0hrL1nu E6bamiee rfnoonbrii avcl ii gCnofoernocgtuirsoe ndsssi,s octhfu etshisrie o dAniasn gaonef robosobisteh, aS tnohcdei ecthtlyien ioircf at thlh eaern adp y MVBAoiic sMhe,ae eIdDli cA UallSd CAaepnet,e Prh.D. LHBaoausrtrvoaan rM,d MA .2U CNA0no1 AiUxv6E,eS RPrAshOit.DyBE. NJUALYS 1H1-1V4,I L20L1E6
among medical practitioners, researchers, and laboratory scientists.
Emma-Allen-Vercoe, Ph.D. Shareef M. Dabdoub, Ph.D.
PhySiciAn AccreditAtion University of Guelph Ohio State University
No Physician Continuing Medical Education Units will be issued for the Congress. Guelph, ON Canada Columbus, OH USA
Attendees may request Certificates of Attendance, free of charge (see below).
David Aronoff, M.D. Charles Darkoh, Ph.D.
clinicAl lAborAtory ScientiSt AccreditAtion Vanderbilt University University of Texas
Nashville, TN USA Houston, TX USA
Microbiology Educational Services is accredited by the California Department of
Health Services to provide continuing education for clinical laboratory scientists. May A. Beamer Curtis J. Donskey, M.D.
University of Pittsburgh Louis Stokes VA Medical Center
Microbiology Educational Services designates this educational activity for a
Pittsburgh, PA USA Case Western Reserve University
maximum of 20.5 continuing education contact hours upon completion of the
Cleveland, OH USA
program and 7.0 continuing education contact hours upon completion of each Kathy Bernard, M.Sc.
workshop. Clinical laboratory scientists should claim only those hours of credit University of Manitoba Eric Dubberke, M.D.
that they actually spent in the educational activity. Winnipeg, Canada Washington University
certificAteS of AttendAnce Karen Carroll, M.D. St. Louis, MO USA
Certificates of Attendance may be requested on the Evaluation Form. Completed Johns Hopkins University Raina N. Fichorova, M.D., Ph.D.
Evaluation Forms, for sessions attended, must be returned to the Registraton Baltimore, MD USA Harvard Medical School
Table before departing the Congress. Certificates will be emailed to attendees. Boston, MA USA
Robert M. Centor, M.D.
curriculAr GoAlS & obJectiveS University of Alabama Sydney M. Finegold, M.D.
Provide information on the latest developments in the field of anaerobic research, Huntsville, AL USA VA Medical Center
including the role of anaerobes in human diseases, the epidemiology of anaerobic West Los Angeles, CA USA
Ramyavardhanee Chandrasekaran
infections, and potential prevention strategies.
Vanderbilt University Jane A. Foster, Ph.D.
Provide recommendations in the diagnosis, screening, and treatment of anaerobic Nashville, TN USA McMaster University
infections, including new laboratory techniques, utilization of antibiotics, and Hamilton, ON Canada
potential of probiotics. Diane M. Citron
R.M. Alden Research Laboratory David Fredricks, M.D.
Provide an understanding for better utilization of the microbiology lab into the
Culver City, CA USA University of Washington
delivery of patient care.
Seattle, WA USA
Sandrine Claus, Ph.D.
diScloSureS The University of Reading Sukirth Ganesan
Disclosures of relevant financial relationships by all session participants are Reading, United Kingdom Ohio State University
provided on pages xiii-xiv. Columbus, OH USA
Sheila Connelly, Ph.D.
evAluAtion formS Synthetic Biologics, Inc. Shiva Garg, Ph.D.
Please complete the Evaluation Form in your Delegate Packet and return it to the Rockville, MD USA Rebiotix Inc.
Registration Table at the completion of the Congress. Roseville, MN USA
Georg Conrads, Ph.D.
University Hospital Caroline Attardo Genco, Ph.D.
Aachen, Germany Tufts University
Boston, MA USA
x xi
A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6 Presenters & Faculty Presenters & Faculty A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6
Dale Gerding, M.D. Leandro A. Lobo, Ph.D. Nisha B. Patel Michael Surette, Ph.D.
VHA2AiNn0 Me1As6e,E dIRLicO UaBlS CEAeNnJUtALeYSr 1H1-1V4,I L20L1E6 FReiod edrea lJ aUnneiivroe,r sBitrya zoilf Rio de Janeiro UNnoirvmearsni,t yO oKf UOSkAlahoma MHacmMAi2alNts0ot1eAnr6,E UORnNOiv BCeEarsniNatJUydALYaS 1H1-1V4,I L20L1E6
Chandrabali Ghose-Paul, Ph.D. Mary-Jane Lombardo, Ph.D. Daniel Paredes-Sabja, Ph.D. Alex G. Therien, Ph.D.
Microbiome Medicine Seres Therapeutics, Inc. Universidad Andrés Bello Merck & Co.
New York, NY USA Cambridge, MA USA Santiago, Chile Kenilworth, NJ USA
Ellie J.C. Goldstein, M.D. Dena Lyras, Ph.D. Akshay D. Paropkari Casey M. Theriot Ph.D.
University of California Monash University Ohio State University North Carolina State University
Los Angeles, CA USA Melbourne, Australia Columbus, OH USA Raleigh, NC USA
Yiping Han, Ph.D. Rajat Madan, M.D. Richard B. Pyles, Ph.D. Glenn S. Tillotson, Ph.D.
Columbia University University of Cincinnati University of Texas Cempra Pharmaceuticals
New York, NY USA Cincinnati, OH USA Galveston, TX USA Chapel Hill, NC USA
Sharon Hillier, M.D. Michael J.G. Mallozzi, Ph.D. Thomas V. Riley, Ph.D. Kerin Tyrrell
University of Pittsburgh University of Arizona University of Western Australia R.M. Alden Research Lab
Pittsburg, PA USA Tucson, AZ USA Crawley, WA Australia Culver City, CA USA
Eric A. Johnson, Ph.D. Jeanne Marrazzo, M.D., M.P.H. Cynthia Sears, M.D. Gayatri Vedantam, Ph.D.
University of Wisconsin University of Alabama Johns Hopkins University University of Arizona
Madison, WI USA Birmingham, AL USA Baltimore, MD USA Tucson, AZ USA
Stuart Johnson, M.D. Elisabeth Nagy, M.D., Ph.D. Anna M. Seekatz, Ph.D. Yuanguo Wang
Loyola University University of Szeged University of Michigan University of South Florida
Maywood, IL USA Szeged, Hungary Ann Arbor, MI USA Tampa, FL USA
Colleen Kelly, M.D. Mauricio Navarro, D.V.M. Jessica Sieber, Ph.D. Mark Wilcox, M.D.
Brown University University of California, Davis University of Minnesota University of Leeds
Providence, RI USA San Bernardino, CA USA Duluth, MN USA Leeds, United Kingdom
Sarah Kuehne, Ph.D. Maribeth Ruth Nicholson, M.D. Joseph S. Solomkin, M.D. Vince Young, M.D.
University of Nottingham Vanderbilt University University of Cincinnati University of Michigan
Nottingham, United Kingdom Nashville, TN USA Cincinnati, OH USA Ann Arbor, MI USA
Ed Kuijper, M.D., Ph.D. Carl Erik Nord, M.D., Ph.D. Joseph A. Sorg, Ph.D. Joseph P. Zackular, Ph.D.
Leiden University Karolinska Institute Texas A&M University Vanderbilt University
Leiden, The Netherlands Stockholm, Sweden College Station, TX USA Nashville, TN USA
Purnima Kumar, Ph.D. Francisca O. Nwaokorie, Ph.D. Sujatha Srinivasan, Ph.D.
Ohio State University University of Lagos University of Washington
Columbus, OH USA Lagos, Nigeria Seattle, WA USA
Paul Lawson, Ph.D. Andrew B. Onderdonk, Ph.D.
University of Oklahoma Harvard Medical School
Norman, OK USA Boston, MA USA
xii xiii
A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6 Disclosure Information Disclosure Information A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6
This Congress has been planned and implemented in accordance with the Participant Disclosure
EsseAn2Nt0ia1Al6 EARreOaBs aEnNdJU APLYSo 1H1l-i1Vc4i,I eL20sL1 E6of the Accreditation Council for Continuing The following presenters do not have financial relationshAi2pN0s 1wA6iEthR cOomBmEeNrJcUAiLaYS l1 H1i-n1Vt4e,I L2r0eL1sE6ts;
Medical Education (ACCME). The Anaerobe Society of the Americas (ASA)
no relationships between commercial interests and first degree relatives exist, and do not
has attempted to ensure balance, independence, objectivity, and scientific rigor
intend to discuss an unapproved/investigative use of commercial product/device.
in this continuing medical education activity. All individuals in a position to
Michael Aldape, Ph.D. Michael J.G. Mallozzi, Ph.D.
control the educational content of this activity, as well as all oral presenters, have
May A. Beamer Elisabeth Nagy, M.D., Ph.D.
disclosed to ASA any financial interests or other relationships they have had in
Kathy Bernard, M.Sc. Mauricio Navarro, D.V.M.
the past 12 months with commercial interests whose product(s) will be referred
Robert M. Centor, M.D. Maribeth Ruth Nicholson, M.D.
to in presentations, may be providing educational grants, or ‘in-kind’ support of
Ramyavardhanee Chandrasekaran Carl Erik Nord, M.D., Ph.D.
this activity.
Georg Conrads, Ph.D. Francisca O. Nwaokorie, Ph.D.
Shareef M. Dabdoub, Ph.D. -- None Andrew B. Onderdonk, Ph.D.
Although the existence of a commercial interest relationship in itself does not
Charles Darkoh, Ph.D. Daniel Paredes-Sabja, Ph.D.
imply bias or decrease the value of presentations, this information is provided
Raina N. Fichorova, M.D., Ph.D Akshay D. Paropkari, Ph.D.
to the audience to allow them to make their own judgments. It remains for
Sydney M. Finegold, M.D. Nisha B. Patel
the audience to determine whether the speaker’s interest or relationships may
Jane A. Foster, Ph.D. Richard B. Pyles, Ph.D.
influence the presentation with regard to exposition or conclusion. David Fredricks, M.D. Cynthia Sears, M.D.
Sukirth Ganesan Jessica Sieber Ph.D.
The ACCME Standards for Commercial Support require that presentations be
Caroline Genco, Ph.D. Joseph A. Sorg, Ph.D.
free of commercial bias and any information regarding commercial products/
Yiping W. Han, Ph.D. Sujatha Srinivasan, Ph.D.
services be based on scientific methods generally accepted by the medical
Sharon Hillier, Ph.D. Michael Surette, Ph.D.
community. If a presentation has discussion of unlabeled/investigational use of Eric A. Johnson, Ph.D. Casey Theriot, Ph.D.
a commercial product, that information must be disclosed to the participants of Purnima Kumar, D.D.S, Ph.D. Kerin Tyrrell
the activity. Paul Lawson, Ph.D. Gayatri Vedantam, Ph.D.
Leandro A. Lobo, Ph.D. Yuanguo Wang
The disclosure information received from each individual is presented on the Rajat Madan, M.D. Joseph P. Zackular, Ph.D.
following pages. All disclosure information has been reviewed for conflict of
interest by the ASA Program Committee. Conflicts identified and resolved are The following presenters have information to disclose as follows:
noted below. If no notation is made, a conflict of interest was not in existence. Emma Allen-Vercoe, Ph.D. Nubiyota (O)
David M. Aronoff, M.D. Summit (C)
Karen Carroll, M.D. Abbott (G), Accelerate Diagnostics (G),
BD Diagnostics (G), Curetis (G), Quidel (C)
Diane M. Citron Anaerobe Systems (S)
Sandrine Claus, Ph.D. Novartis (G)
Sheila Connelly, Ph.D. Synthetic Biologics (E, O)
Mike Cox Anaerobe Systems (E, O)
Laura M. Cox, Ph.D. Anaerobe Systems (O), Symbiotic Health (C)
Curtis J. Donskey, M.D. 3M (C), Cepheid (G), Ecolab (G), Merck (G),
Pfizer (G) Seres Health (C)
Erik R. Dubberke, M.D. Merck (C, G), Rebiotix (C, G), Sanofi
Pasteur (C, G), Summit (C )
Will discuss results of clinical trials
Shiva Garg, Ph.D. Rebiotix (E)
Dale Gerding, M.D. Actelion (C), DaVolterra (C), Merck (C), Pfizer (C),
Rebiotix (C), Seres (C), SanofiPasteur (C) Summit
(C), ViroPharma/Shire (C)
xiv xv
A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6 Disclosure Information Congress Program A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6
Chandrabali Ghose-Paul, Ph.D. Symbiotic Health (E) Monday, July 11
EllieA 2J.NC0.1A G6EoRldOsteBinE, MNJUA.LDYS 1.H 1-1V4,I L20L1E6 ABamyiecrr oPbhea (rGm)a, cAeustteicllaalss ((GA),, SA)v, iBdiboKio+ti c(sA ()G, C),e rexa 00 WORKSHOPS & CONGRESS REGISTRAA2TN0IO1A6NER OOPBEENNSJUALYS 1H1-1V4,I L20L1E6
(G), Clinical Microbiology Institute (G), Durata 8
(G), Forrest Pharmaceuticals (G), Genzyme (G),
GlaxoSmith Kline (G), GLSynthesis (G), Gynuity 00 ANAEROBIC IDENTIFICATION & SUSCEPTABLITY WORKSHOP
7
Health Projects (G), Immunome (G), Impex 1 Diane M. Citron
-
Pharmaceuticals (G), Kindred Healthcare (A), Merck 0
0 Mike Cox
& Co (A, G, S), Nanopacific Holdings Inc. (G), 9
Novartis (A, G), Pfizer (G), Rempex (A, G) Romark
Laboratories (G), Sankyo-Daichi (A), Salix (G), ExAMINING ANAEROBES IN THE MICROBIOME:
Sanofi-Adventis (A), Summit (A, G), Symbiomix 0 METAGENOMIC AND CULTURE APPROACHES
0
Therapeutics (G), The Medicines Company (G), 7
1 Laura M. Cox, Ph.D.
Theravance (G), Toltec Pharmaceuticals (G), Viroxis -
0
(G), Warner Chilcott (G) 0 Casey Theriot, Ph.D
9
Stuart Johnson, M.D. BioK+ International (C), Seres Therapeutics (C), Anna Seekatz, Ph.D.
Summit Therapeutics (C)
Will discuss Investigational Products
Colleen Kelly, M.D. Assembly Biosciences (R ), Seres Health (C) 0 BLUES, BREWS & BBQ AT BB KINGS
0
Sarah Kuehne, Ph.D. Summit (G) 18 152 2nd Ave. N.
Ed Kuijper, M.D., Ph.D. Astellas (C), Actelion (C), DaVolterra (C), Merck (C),
Valneva (C, G)
Mary-Jane Lombardo Seres (E, O)
SER-262 is an investigational product
Dena Lyras, Ph.D. Immuron Limited (C)
Jeanne Marrazzo, MD. Cepheid (C), Perrigo (C), Toltec (G)
Thomas V. Riley, Ph.D. Alere (R)
Anna Seekatz, Ph.D. Medimmune (G)
Joseph S. Solomkin, M.D. AstraZeneca (C) Merck (C), Pfizer (C), Tetraphase (C)
Alex G. Therien, Ph.D. Merck (E, S)
Glenn S. Tillotson, Ph.D. Cempra Pharmaceuticals (E) Summit (R)
Mark Wilcox, M.D. Abbott (G), Actelion (C,G), Alere (C,G), Astellas (C,
G), Astra Zeneca (C, G), Basilea (C), Biomerieux (G),
Bayer (C), Cerexa (G), Cubist (C, G), Da Volterra
(G), Durata (C), European Tissue Symposium (C, G),
Johnson & Johnson (C), Merck (C,G), Nabriva (C),
Novacta (C), Optimer (C), Pfizer (C, S), Qiagen (G),
Roche (C), Sanofi-Pasteur (G), Seres (C), Summit (G),
The Medicines Company (G)
Vincent Young, M.D. Medimmune (G), Merck (C), Vedante (C)
C=Consultant, E-Employment, G=Grants, O=Ownership/Stock, R-Research, S=Speaker
xvi xvii
A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6 Congress Program Congress Program A2N01A6EROBE NJUALYS 1H1-V14I, L20L1E6
Tuesday, July 12
0
705 A2RN0E1AG6EIRSTORBAETNJIUOALYS N1H1- 1V/4 ,IB L20RL1E6EAKFAST / ExHIBITS 1200-1315 LSUTUNDCEHN / TE xCHOIMBIPTEST I TION PREA2SN0E1AN6ETRAOTBIOENNJSUALYS 1H1-1V4,I L20L1E6
2 WELCOME REMARKS
8 1315-1415 POSTER SESSION I / ExHIBITS
-
5 David Aronoff, M.D., ASA President
1
8 SESSION IV: DEFINING THE FUNCTION OF THE GUT USING
OMIC APPROACHES FOR RATIONAL DESIGN OF
SESSION I: TREATING MULTI-DRUG RESISTANT INFECTIONS
PERSONALIZED THERAPEUTICS
IN THE ERA OF ANTIMICROBIAL STEWARDSHIP
Convener: Casey M. Theriot, Ph.D.
Convener: Ellie Goldstein, M.D.
SIV-1 Rational Design of Microbiota-Mediated Secondary Bile Acids
SI-1 The Clinical Presentation of Fusobacterium necrophorum Pharyngitis 1
in the Gut to Restore Colonization Resistance against C. difficile 4
Robert M. Centor, M.D. 1
5 Casey M. Theriot, Ph.D. 5
5-94 SI-2 TWhhea Nt Aewre Athgee nTtrsia flosr S Cayoimngp?li cated Intra-Abdominal Infections: SIV-2 Nutrimetabonomics to Understand Host-Pathogen Response to -153
2 Antibiotic Treatment 0
8 Joseph S. Solomkin, M.D.
Sandrine Claus, Ph.D.
SI-3 Parallels between C. difficile Colitis and Autism
SIV-3 Methanogens in the Gut and their Interactions with Beneficial
Sydney M. Finegold, M.D. Butyrate Producers
SI-4 The Non-Existent Drug Pipeline for Anaerobic Infections Jessica Sieber, Ph.D.
Ellie J.C. Goldstein, M.D.
1530-1545 BREAK / ExHIBITS
945-1000 BREAK / ExHIBITS
SESSION V: LITERATURE REVIEW IN ANAEROBIC SCIENCES
SESSION II: KEYNOTE ADDRESS 1
0 SV-1 An Update on Fusobacterium Disease Pathogenesis 5
000-110 SII-1 C NColeonvsvtererin dLeirue:mt Da d aCivfrfiiidcsi ilAse rGTornoao ntfofs, mWMias.Dssit.oe:n Progress in Prevention of S V-2 BacteCryonidtheisa: SBeeayros,n Md .tDhe. Microbiome 45-1645
1 Glenn S. Tillotson, Ph.D.
Curtis J. Donskey, M.D.
SESSION III: Oral abStractS: NON-dIffIcIlE clOStrIdIa SESSION VI: ORAL ABSTRACTS: POTPOURRI
aNd INtra-abdOmINal INfEctIONS Convener: David Fredricks, M.D.
Convener: Andrew B. Onderdonk, Ph.D. SVI-1 Taking the Next Giant Step: Designed Microbiome Therapeutics
SIII-1 Diet Fiber Contributes to Peritonitis by Activating Inflammasome for Clostridium difficile Infection (CDI) 16
Nlrp3 and Inducing IL-1ß Secretion Mary-Jane Lombardo, Ph.D. 45
-
Leandro A. Lobo, Ph.D. SVI-2 ‘In Silico’ Chemotaxonomy: A Tool for Microbial Systematics 1
7
3
SIII-2 Detection of Toxigenic Clostridium perfringens and Clostridium Nisha B. Patel 0
00 botulinum from Food Commodities in Lagos State, Nigeria SVI-3 First Genome Sequence of the Opportunistic Pathogen
2
1 Francisca O. Nwaokorie, Ph.D. Clostridium septicum
-
00 SIII-3 Purification and Properties of a Novel Botulinum Neurotoxin Michael J.G. Mallozzi, Ph.D.
1
1 FA “H”
Eric A. Johnson, Ph.D. ANAEROBE SOCIETY MEMBERSHIP MEETING 17
3
SIII-4 Pathology of Bacillary Hemoglobinuria Produced by 0
Clostridium haemolyticum 1
8
Mauricio Navarro, D.V.M. 0
WINE & CHEESE RECEPTION / LEGISLATIVE TERRACE 0
-
SIII-5 The Comparative Efficacy of Antibiotics against Experimental 1
9
Clostridium septicum Infection 0
0
Michael Aldape, Ph.D.
xviii xix