Nanotechnology in Modern Animal Biotechnology Concepts and Applications This page intentionally left blank Nanotechnology in Modern Animal Biotechnology Concepts and Applications Edited by PAWAN KUMAR MAURYA, PHD Associate Professor Department of Biochemistry Central University of Haryana Mahendergarh, India SANJAY SINGH, PHD Associate Professor Division of Biological and Life Sciences School of Arts and Sciences Central Campus, Ahmedabad University Ahmedabad, Gujarat, India ] NANOTECHNOLOGYINMODERNANIMALBIOTECHNOLOGY ISBN:978-0-12-818823-1 Copyright(cid:1)2019ElsevierInc.Allrightsreserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permissioninwritingfromthepublisher.Detailsonhowtoseekpermission,furtherinformationaboutthe Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance CenterandtheCopyrightLicensingAgency,canbefoundatourwebsite:www.elsevier.com/permissions. This book and the individual contributions contained in it are protected under copyright by the Publisher (otherthanasmaybenotedherein). Notices Practitionersandresearchersmustalwaysrelyontheirownexperienceandknowledgeinevaluatingand usinganyinformation,methods,compoundsorexperimentsdescribedherein.Becauseofrapidadvances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors or contributors for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas containedinthematerialherein. Publisher:OliverWalter AcquisitionEditor:SeanSimms EditorialProjectManager:ThomasVanderPloeg ProductionProjectManager:SreejithViswanathan CoverDesigner:AlanStudholme 3251RiverportLane St.Louis,Missouri63043 List of Contributors TaruAggarwal SagarikaBiswas, PhD AmityInstitute ofBiotechnology SeniorPrincipal Scientist AmityUniversityUttarPradesh Department ofGenomics &Molecular Medicine Noida, UttarPradesh, India CSIR-Institute of Genomics&IntegrativeBiology NewDelhi,India HomicaArya BiologicalandLifeSciences PranjalChandra,MSc,MTech, PhD School ofArtsandSciences Laboratoryof Bio-PhysioSensorsand AhmedabadUniversity Nanobioengineering CentralCampus Department ofBiosciencesandBioengineering Ahmedabad, Gujarat,India Indian Instituteof TechnologyGuwahati Guwahati, Assam,India AdityaArya,PhD StaffScientist DineshKumarChellappan Centrefor Bioinformatics Department ofLifeSciences ComputationalandSystemsBiology School ofPharmacy PathfinderResearchandTrainingFoundation International MedicalUniversity GreaterNoida, UttarPradesh, India Bukit Jalil,Malaysia MalvikaBakshi TrudiCollet, PhD BiologicalandLifeSciences Indigenous MedicinesGroup School ofArtsandSciences Institute ofHealth &Biomedical Innovation AhmedabadUniversity QueenslandUniversityof Technology CentralCampus Brisbane, QLD,Australia Ahmedabad, Gujarat,India VikramDalal IvneetBanga Department ofBiotechnology AmityInstitute ofBiotechnology Indian Instituteof TechnologyRoorkee AmityUniversity Roorkee, Uttarakhand,India Noida, UttarPradesh, India Shrusti Dave Department ofBioengineering Biological andLifeSciences UniversityofTexas School ofArtsandSciences Dallas,TX, UnitedStates AhmedabadUniversity SubhashiniBharathala CentralCampus Ahmedabad, Gujarat,India Centrefor BiomedicalTechnology AmityInstitute ofBiotechnology AmityUniversity Noida, UttarPradesh, India v vi LISTOFCONTRIBUTORS KamalDua, PhD PhilipMichael Hansbro,PhD Disciplineof Pharmacy School ofLifeSciences GraduateSchool ofHealth FacultyofScience UniversityofTechnologySydney UniversityofTechnologySydney(UTS) Broadway,NSW,Australia Ultimo, NSW,Australia PriorityResearchCentrefor HealthyLungs Centrefor Inflammation UniversityofNewcastle&HunterMedical CentenaryInstitute ResearchInstitute Sydney,NSW,Australia Newcastle,NSW,Australia Priority ResearchCentre forHealthyLungs Centrefor Inflammation UniversityofNewcastle&Hunter MedicalResearch CentenaryInstitute Institute Sydney,NSW,Australia Newcastle, NSW,Australia AkhilGajipara AshutoshKumar BiologicalandLifeSciences LaboratoryofBio-Physio SensorsandNano Schoolof ArtsandSciences bioengineering AhmedabadUniversity Department ofBiosciencesandBioengineering CentralCampus IndianInstitute ofTechnologyGuwahati Ahmedabad,Gujarat, India Guwahati, Assam,India SonuGandhi RameshKumar DBT-NationalInstitute ofAnimal Biotechnology Department ofBiochemistry Hyderabad, Telangana,India UniversityofAllahabad Allahabad, UttarPradesh, India RishaGanguly Department ofBiochemistry Amit Kumar,PhD UniversityofAllahabad International ResearchCentre Allahabad,UttarPradesh, India SathyabamaInstitute of ScienceandTechnology Chennai,TamilNadu, India AnamikaGangwar,MSc DefenceInstitute ofPhysiology andAllied Sciences KuldeepMahato Delhi,India LaboratoryofBio-Physio SensorsandNano bioengineering MonicaGulati,PhD Department ofBiosciencesandBioengineering Schoolof Pharmaceutical Sciences IndianInstitute ofTechnologyGuwahati FacultyofAppliedMedicalSciences Guwahati, Assam,India LovelyProfessional University Phagwara,Punjab,India PawanKumarMaurya,PhD AssociateProfessor AshutoshGupta Department ofBiochemistry Department ofBiochemistry CentralUniversityofHaryana UniversityofAllahabad Haryana,India Allahabad,UttarPradesh, India V.G.M.Naidu GauravGupta Department ofPharmacology andToxicology Schoolof Pharmaceutical Sciences NIPER Guwahati JaipurNationalUniversity Guwahati, Assam,India Jagatpura,Rajasthan,India LISTOF CONTRIBUTORS vii MastanMukram Naikwade SharmiliRoy Department ofPharmacologyandToxicology LaboratoryofBio-Physio Sensorsand NIPERGuwahati Nanobioengineering Guwahati,Assam,India Department ofBiosciencesandBioengineering IndianInstitute ofTechnologyGuwahati RonyNunes,SPC Guwahati, Assam,India LaboratoryofExtracellularMatrixandGeneExpression Regulation VijaylaxmiSaxena Department ofStructural andFunctional Biologye Biological andLifeSciences Instituteof BiologyeUNICAMP,Brazil School ofArtsandSciences AhmedabadUniversity BrianOliver,PhD CentralCampus Schoolof LifeSciences Ahmedabad, Gujarat,India FacultyofScience UniversityofTechnologySydney(UTS) JuhiShah Ultimo,NSW,Australia Biological andLifeSciences School ofArtsandSciences AbhayK.Pandey AhmedabadUniversity Department ofBiochemistry CentralCampus UniversityofAllahabad Ahmedabad, Gujarat,India Allahabad,UttarPradesh, India Maitri Shah AkhileshKumarPandey Biological andLifeSciences Department ofSurgeryandNeurology School ofArtsandSciences TexasTechUniversityHealth SciencesCentre AhmedabadUniversity Lubbock,TX,UnitedStates CentralCampus Ahmedabad, Gujarat,India LilianCristinaPereira,PhD Department ofBioprocessesandBiotechnology RutviShah CollegeofAgronomySciences(FCA) Biological andLifeSciences SãoPauloState University(UNESP)-Centerfor School ofArtsandSciences Evaluationof Environmental ImpactonHuman AhmedabadUniversity Health(TOXICAM) CentralCampus Botucatu,SãoPaulo,Brazil Ahmedabad, Gujarat,India BuddhadevPurohit DeepshikhaShahdeo LaboratoryofBio-Physio SensorsandNano DBT-National Institute ofAnimalBiotechnology bioengineering (DBT-NIAB) Department ofBiosciencesandBioengineering Hyderabad, Telangana,India IndianInstitute ofTechnologyGuwahati Guwahati,Assam,India AnmolShamal Biological andLifeSciences ThaniaRiosRossiLima, MSc School ofArtsandSciences Department ofPathology AhmedabadUniversity BotucatuMedical School CentralCampus SãoPauloState University(UNESP)-Centerfor Ahmedabad, Gujarat,India Evaluationof Environmental ImpactonHuman Health(TOXICAM) Botucatu,SãoPaulo,Brazil viii LISTOFCONTRIBUTORS PankajSharma,PhD RoshikaTyagi Professor AmityInstitute ofBiotechnology Centrefor BiomedicalTechnology AmityUniversity AmityInstitute ofBiotechnology Noida, UttarPradesh,India AmityUniversity Noida,UttarPradesh, India AkdasbanuVijapura Biological andLifeSciences AmitKumarSingh School ofArtsandSciences Department ofBiochemistry AhmedabadUniversity UniversityofAllahabad CentralCampus Allahabad,UttarPradesh, India Ahmedabad, Gujarat,India SanjaySingh,PhD AashnaVyas AssociateProfessor Biological andLifeSciences DivisionofBiologicalandLifeSciences School ofArtsandSciences Schoolof ArtsandSciences AhmedabadUniversity CentralCampus,AhmedabadUniversity CentralCampus Ahmedabad,Gujarat, India Ahmedabad, Gujarat,India AnanyaSrivastava RidhimaWadhwa Department ofPharmacologyandToxicology FacultyofLifeSciencesandBiotechnology NIPERGuwahati SouthAsianUniversity Guwahati,Assam,India NewDelhi,India PrachiThakore KylieWilliams,PhD BiologicalandLifeSciences Discipline ofPharmacy Schoolof ArtsandSciences GraduateSchool ofHealth AhmedabadUniversity UniversityofTechnologySydney CentralCampus Broadway,NSW,Australia Ahmedabad,Gujarat, India NoopurThapliyal AmityInstitute ofBiotechnology AmityUniversityUttarPradesh Noida,UttarPradesh, India Contents 1 Biosensors and Their Application for 6 Biosensors in Animal Biotechnology,75 theDetectionofAvianInfluenzaVirus,1 AdityaArya,PhD,AnamikaGangwar,MScand IvneetBanga,RoshikaTyagi, Amit Kumar,PhD DeepshikhaShahdeoandSonuGandhi 7 Nanoparticle-Mediated Oxidative 2 Nanoparticle-Mediated Oxidative Stress Monitoring and Role Stress Monitoring,17 of Nanoparticle for Treatment ThaniaRiosRossiLima,MSc of Inflammatory Diseases,97 RonyNunes, SPCand Vikram DalalandSagarikaBiswas, PhD LilianCristina Pereira,PhD 8 Biomedical Applications of 3 Nanoparticles as Modulators Nanoparticles,113 of Oxidative Stress,29 Subhashini Bharathalaand RishaGanguly, AmitKumarSingh,Ramesh Pankaj Sharma,PhD Kumar,AshutoshGupta,AkhileshKumar PandeyandAbhayK.Pandey 9 Cancer Cytosensing Approaches in Miniaturized Settings Based on 4 Nanomaterials-Based Next Generation Advanced Nanomaterials and SyntheticEnzymes:CurrentChallenges Biosensors,133 and Future Opportunities in Biological BuddhadevPurohit, AshutoshKumar, Applications,37 Kuldeep Mahato,Sharmili Royand JuhiShah, ShrustiDave,AashnaVyas,Maitri Pranjal Chandra,MSc, MTech,PhD Shah,HomicaArya,AkhilGajipara,Akdasbanu Vijapura,MalvikaBakshi,PrachiThakore,Rutvi 10 Nanotherapeutics: A Novel and Shah, VijaylaxmiSaxena,AnmolShamal and Powerful Approach in Modern SanjaySingh, PhD Healthcare System,149 Ashutosh Kumar,Sharmili Roy, 5 Nanoparticle-Based Drug Delivery for AnanyaSrivastava,MastanMukramNaikwade, Chronic Obstructive Pulmonary BuddhadevPurohit, KuldeepMahato, V.G.M. Disorder and Asthma: Progress and NaiduandPranjalChandra, MSc,MTech, PhD Challenges,59 RidhimaWadhwa,TaruAggarwal, INDEX, 163 NoopurThapliyal, DineshKumarChellappan, GauravGupta,MonicaGulati, PhD TrudiCollet,PhD, BrianOliver,PhD KylieWilliams,PhD, PhilipMichael Hansbro, PhD, KamalDua, PhDand PawanKumarMaurya,PhD ix