Nanotechnology Applied To Pharmaceutical Technology

388 Pages·2017·6.71 MB·English

by  Mahendra Rai

Mahendra Rai
Carolina Alves dos Santos
Editors
Nanotechnology
Applied To
Pharmaceutical
Technology
Nanotechnology Applied To Pharmaceutical
Technology
Mahendra Rai Carolina Alves dos Santos
(cid:129)
Editors
Nanotechnology Applied To
Pharmaceutical Technology
123
Editors
Mahendra Rai Carolina Alves dosSantos
Department ofBiotechnology Schoolof Pharmaceutical Sciences
SGBAmravati University University of Sorocaba
Amravati, Maharashtra Sorocaba,São Paulo
India Brazil
ISBN978-3-319-70298-8 ISBN978-3-319-70299-5 (eBook)
https://doi.org/10.1007/978-3-319-70299-5
LibraryofCongressControlNumber:2017957191
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Preface
Pharmaceutical technology is based on the use of different technologies for the
preparation and development of pharmaceutical products. It is a branch of the
pharmaceuticalsciencesconstantlylinkedtothedevelopmentanduseofinnovative
technologies for the production and development of products with maximum
effectiveness, adequate dosage, and stable formulations, aiming at different appli-
cations in living beings.
Nanotechnology is a recent, highly interdisciplinary and versatile branch of
science that allows to develop products with interesting and novel structural
characteristics totally different from those obtained by the compounds in their
conventional form, a fact that attributes differentiated properties and specific
interaction mechanisms, which adds technological value to the newly developed
products. Thus, the useof nanotechnology in thepharmaceuticalscience promotes
thedesignanddevelopmentofproductsknownasnanopharmaceuticals,whichare
composed of nanoscaleproperties withslow drug release systems, as stabilizers of
formulations, pharmaceutical activities, or systems for detection and evaluation.
The possibility of obtaining different mechanisms of response provided by the
nanotechnologically developed products allows varied combinations enriching the
range of products to be developed from this technology.
In this context, the book seeks to integrate the pharmaceutical sciences with
nanotechnologyasawaytoobtaininnovativeproductsandsolutionsappliedtothe
pharmacy. It provides the reader with a broad vision where nanotechnology is
employed with different perspectives and applications. This approach focuses on
theapplicationofnanotechnologyinpharmaceuticaltechnologyandalsorepresents
aninterdisciplinary naturethat canbeusedbypeopleinterestedinexpandingtheir
knowledge in applied nanotechnology.
v
vi Preface
The present book is highly interdisciplinary and would be very useful for a
diverse group of readers including pharmacologists, nanotechnologists, microbi-
ologists,biotechnologists, clinicians, andthose,who areinterestedin development
of nanoproducts. The students should find this book useful and reader-friendly.
Amravati, India Mahendra Rai
Sorocaba, Brazil Carolina Alves dos Santos
The original version of the book was revised.
Theincorrectcountrynameinpreface“Sorocaba,India”
has been corrected as “Sorocaba, Brazil”.
Contents
Part I General
1 Bioinspired Metal Nanoparticles with Special Reference to
Mechanism . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3
Magdalena Wypij and Patrycja Golinska
2 Nano-antimicrobials: A Viable Approach to Tackle
Multidrug-Resistant Pathogens . . . . . . . . . . . . . . . . . . . . . . . . . . . . 31
Bushra Jamil and Muhammad Ali Syed
3 Nanoliposomes as a Platform for Delivery of Antimicrobials . . . . . 55
Adriano Brandelli, Cristian Mauricio Barreto Pinilla
and Nathalie Almeida Lopes
4 Synthesis of Metal Oxide Nanoparticles and Its Biomedical
Applications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91
Zygmunt Sadowski and Agnieszka Pawlowska
5 Nanotechnology: A Tool for Targeted Drug Delivery . . . . . . . . . . . 113
Suchitra S. Mishra, Kunal B. Banode and Veena S. Belgamwar
6 Pharmaceutical Applications of Curcumin-Loaded
Nanoparticles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139
Mahendra Rai, Raksha Pandit, Priti Paralikar, Dipali Nagaonkar,
Farkhanda Rehman and Carolina Alves dos Santos
Part II Nanoparticles/Nanoformulations for Diseases and Patents
7 Nanoformulations for Cancer Therapy. . . . . . . . . . . . . . . . . . . . . . 157
Amaresh Kumar Sahoo, Arushi Verma and Prerna Pant
8 Nanoformulations for Vaginal Therapy . . . . . . . . . . . . . . . . . . . . . 183
Željka Vanić and Nataša Škalko-Basnet
ix
x Contents
9 Nanoformulations for Wound Infections. . . . . . . . . . . . . . . . . . . . . 223
Avinash P. Ingle, Priti Paralikar, Raksha Pandit, Netravati Anasane,
Indarchand Gupta, Mahendra Rai, Marco V. Chaud
and Carolina Alves dos Santos
10 Lipid-Based Nanoformulations for Treatment of
Skin Diseases. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 247
Sajjad Janfaza and Seyedehhamideh Razavi
11 Anti-Proliferative Activity of Curcumin Loaded PLGA
Nanoparticles for Prostate Cancer . . . . . . . . . . . . . . . . . . . . . . . . . 267
Md. Asad Khan, Salman Ahmad, Irfan Ahmad
and M. Moshahid A. Rizvi
12 Nanotechnological Interventions for Drug Delivery in Eye
Diseases. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 279
Avinash P. Ingle, Priti Paralikar, Alex Grupenmacher,
Felipe Hering Padovani, Marilia Trindade Ferrer, Mahendra Rai
and Monica Alves
13 Role of Nanoparticles in Treatment of Human Parasites . . . . . . . . 307
M. E. Della Pepa, F. Martora, E. Finamore, M. Vitiello, M. Galdiero
and G. Franci
14 Patents Survey: Treatment of Alzheimer’s Disease Through
Nanotechnology-Based Drug Delivery System. . . . . . . . . . . . . . . . . 335
Rashmin B. Patel, Shivam D. Thakore and Mrunali R. Patel
Part III Toxicity
15 Nanomaterials: Properties, Toxicity, Safety,
and Drug Delivery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363
Luiza Helena da Silva Martins, Mahendra Rai, João Moreira Neto,
Johnatt Allan Rocha de Oliveira, Júlia Helena da Silva Martins,
Andrea Komesu, Debora Kono Taketa Moreira
and Paulo Weslem Portal Gomes
Index .... .... .... .... .... ..... .... .... .... .... .... ..... .... 383
Contributors
IrfanAhmad DepartmentofBiosciences,JamiaMilliaIslamia,NewDelhi,India
Salman Ahmad Department of Biosciences, Jamia Millia Islamia, New Delhi,
India
Monica Alves Department of Ophthalmology and Othorrinolaringology, Faculty
of Medical Sciences, University of Campinas, Campinas, Brazil
NetravatiAnasane NanobiotechnologyLaboratory,DepartmentofBiotechnology,
SGBAmravatiUniversity,Amravati,Maharashtra,India
Md. Asad Khan Department of Biochemistry, Faculty of Dentistry, Jamia Millia
Islamia, New Delhi, India
Kunal B. Banode University Department of Pharmaceutical Sciences, Rastrasant
Tukadoji Maharaj Nagpur University, Nagpur, India
Veena S. Belgamwar University Department of Pharmaceutical Sciences,
Rastrasant Tukadoji Maharaj Nagpur University, Nagpur, India
AdrianoBrandelli LaboratóriodeBioquímicaeMicrobiologiaAplicada,Instituto
deCiênciaeTecnologiadeAlimentos,UniversidadeFederaldoRioGrandedoSul,
Porto Alegre, Brazil
MarcoV.Chaud LabNUSSchoolofPharmaceuticalSciences—Biomaterialsand
Nanotechnology Laboratory, University of Sorocaba, Sorocaba, São Paulo, Brazil
M. E. Della Pepa Experimental Medicine Department, University of Campania
“Luigi Vanvitelli”, Naples, Italy
MariliaTrindadeFerrer DepartmentofOphthalmologyandOthorrinolaringology,
FacultyofMedicalSciences,UniversityofCampinas,Campinas,Brazil
E.Finamore ExperimentalMedicineDepartment,UniversityofCampania“Luigi
Vanvitelli”, Naples, Italy
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