NANOBIOMATERIALS Applications in Drug Delivery NANOBIOMATERIALS Applications in Drug Delivery Edited By Anil K. Sharma, MPharm Raj K. Keservani, MPharm Rajesh K. Kesharwani, PhD Apple Academic Press Inc. Apple Academic Press Inc. 3333 Mistwell Crescent 9 Spinnaker Way Oakville, ON L6L 0A2 Waretown, NJ 08758 Canada USA © 2018 by Apple Academic Press, Inc. No claim to original U.S. Government works Printed in the United States of America on acid-free paper International Standard Book Number-13: 978-1-77188-591-1 (Hardcover) International Standard Book Number-13: 978-1-315-20491-8 (eBook) All rights reserved. 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Sharma, Anil K., 1980-, editor II. Keservani, Raj K., 1981-, editor III. Kesharwani, Rajesh Kumar, 1978-, editor RS199.5.N36 2017 615'.6 C2017-905673-5 C2017-905674-3 CIP data on file with US Library of C ongress Apple Academic Press also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic format. For information about Apple Academic Press products, visit our website at www.appleacademicpress.com and the CRC Press website at www.crcpress.com CONTENTS Dedication ......................................................................................................vii Contributors ....................................................................................................ix Abbreviations ................................................................................................xiii Preface .........................................................................................................xvii About the Editors...........................................................................................xxi PART I: AN OVERVIEW OF NANOBIOMATERIALS ....................................1 1. Nanoparticulate Nanocarriers in Drug Delivery .........................................3 Raj K. Keservani, Anil K. Sharma, and Rajesh K. Kesharwani 2. Nanoparticles: Formulation Aspects and Applications ............................23 Sushama Talegaonkar, Lalit Mohan Negi, Harshita Sharma, and Sobiya Zafar 3. Physical and Chemical Properties of Nanobiomaterials ..........................75 Sumitra Nain, Garima Mathur, Pragati Karana, and Hari Om Singh PART II: DRUG DELIVERY AND NANOTECHNOLOGY ...........................89 4. Introduction to Drug Delivery ....................................................................91 Mila A. Emerald 5. Application of Nanobioformulations for Controlled Release and Targeted Biodistribution of Drugs ............................................................131 Josef Jampílek and Katarína Kráľová 6. Targeted Delivery Systems Based on Polymeric Nanoparticles for Biomedical Applications ......................................................................209 Sa Yang, Can Huang, Zhi-Ping Li, Qian Ning, Wen Huang, Wen-Qin Wang, and Cui-Yun Yu 7. Smart Delivery of Nanobiomaterials ........................................................241 Mirza Sarwar Baig, Raj K. Keservani, Mohd Fasih Ahmad, and Mirza Ehtesham Baig vi Contents PART III: NANOBIOMATERIALS AS CARRIERS IN CANCER THERAPEUTICS ......................................................................................289 8. Advances of Nanotechnology in Cancer Therapy ...................................291 Urmila Jarouliya, Raj K. Keservani, and Rajesh K. Kesharwani 9. Nanobiomaterials for Cancer Diagnosis and Therapy ...........................329 Cecilia Cristea, Florin Graur, Ramona Gălătuş, Călin Vaida, Doina Pîslă, and Robert Săndulescu 10. Nanobiomaterials for Cancer Therapy ....................................................377 Kevin J. Quigley and Paul Dalhaimer 11. Nanotechnology in Hyperthermia-Based Therapy and Controlled Drug Delivery ..........................................................................395 Anamaria Orza and Christopher Clark PART IV: DIVERSE USES OF NANOBIOMATERIALS..............................415 12. Nano Carrier Systems of Ubidecarenone (Coenzyme Q10) for Cosmetic Applications ................................................................................417 N. K. Yadav, Rekha Rao, O. P. Katare, and Sanju Nanda 13. Nanobased CNS Delivery Systems ............................................................441 Rahimeh Rasouli, Mahmood Alaei-Beirami, and Farzaneh Zaaeri 14. Nanobiomaterial for Non-Viral Gene Delivery .......................................475 Kirti Rani Sharma Index .............................................................................................................505 DEDICATION The Present Book is Dedicated to Our Beloved Aashna, Atharva, and Vihaan CONTRIBUTORS Mohd Fasih Ahmad Barrocyte Pvt. Ltd., 105, First Floor, Block No-CHBS, Sukhdev Vihar CSC, Near Fortis-Escorts Hospital, New Delhi, 110025, India Mirza Ehtesham Baig Barrocyte Pvt. Ltd., 105, First Floor, Block No-CHBS, Sukhdev Vihar CSC, Near Fortis-Escorts Hospital, New Delhi, 110025, India Mirza Sarwar Baig Department of Biosciences, Jamia Millia Islamia (A Central University), New Delhi, 110025, India Mahmood Alaei-Beirami Drug Applied Research Center and Students’ Research Committee, Tabriz University of Medical Science, Tabriz, Iran/Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran Christopher Clark The Movement Group, Inc., Atlanta, Georgia, The United States of America Cecilia Cristea Analytical Chemistry Department, Faculty of Pharmacy, Iuliu Hațieganu University of Medicine and Pharmacy, 4 Pasteur St., 400012, Cluj-Napoca, Romania, E-mail: [email protected] Paul Dalhaimer Department of Chemical and Biomolecular Engineering, University of Tennessee, Knoxville, TN, 37996, USA, E-mail: [email protected]/Department of Biochemistry, Cellular and Molecular Biology, University of Tennessee, Knoxville, TN 37996, USA Mila A. Emerald Phytoceuticals InternationalTM and Novotek Global SolutionsTM, Ontario, Canada, E-mail: [email protected] Ramona Gălătuș Basis of Electronics Department, Faculty of Electronics, Telecommunication and Information Technology, Technical University of Cluj-Napoca, 28 Memorandumului St., 400114 Cluj-Napoca, Romania Florin Graur Surgical Department, Faculty of Medicine, Iuliu Hațieganu University of Medicine and Pharmacy, 8 Victor Babes St., 400012, Cluj-Napoca, Romania Can Huang Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China, Hengyang, 421001, China, E-mail: [email protected] Wen Huang Learning Key Laboratory for Pharmacoproteomics of Hunan Province, Institute of Pharmacy and Pharmacology, University of South China, Hengyang, 421001, China Josef Jampílek Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University, Odbojárov 10, 83232, Bratislava, Slovakia, E-mail: [email protected]