Nail Psoriasis: From A to Z

160 Pages·2014·4.714 MB·English

by  Dimitris Rigopoulos, Antonella Tosti (eds.)

Dimitris Rigopoulos
Antonella Tosti
Editors
Nail Psoriasis
From A to Z
123
Nail Psoriasis

Dimitris Rigopoulos (cid:129) Antonella Tosti
Editors
Nail Psoriasis
From A to Z
Editors
Dimitris Rigopoulos , MD Antonella Tosti , MD
Department of Dermatology Department of Dermatology
Athens University School and Cutaneous Surgery
of Medicine University of Miami
Athens Miller School of Medicine
Greece Miami , FL
USA
ISBN 978-3-319-08809-9 ISBN 978-3-319-08810-5 (eBook)
DOI 10.1007/978-3-319-08810-5
Springer Cham Heidelberg New York Dordrecht London
Library of Congress Control Number: 2014950054
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Pref ace
P soriasis is a very common skin condition that clearly infl uences the quality of life
and mental equilibrium of affected patients. Recent research data have expanded
greatly our knowledge on psoriasis both in terms of the underlying pathogenetic
mechanisms and treatment options. Furthermore, recognition of the fact that the
disease does not affect only skin, but is often accompanied with various comorbidi-
ties, has changed our point of view on this entity, while new treatment modalities
with new therapeutic agents have contributed signifi cantly to the modern view of
psoriasis as a systemic disease.
About half of the people who have psoriasis also have changes affecting their
nails. Psoriatic nail disease is very variable in appearance and severity. The diversity
of clinical appearance in psoriatic nail disease poses exceptional interest to the
whole scientifi c community that is refl ected with the huge increase of publications
on this topic during the last years.
S o, we thought that this is the ideal timing to deal with the state-of-the-art knowl-
edge of nail psoriasis and organize a special book on this topic. In order to cover the
full extent of the subject, we invited all those who are considered experts and opin-
ion leaders on this fi eld, to share their knowledge and transfer their valuable experi-
ences on each specifi c topic of the book.
A ll medical specialists as dermatologists, rheumatologists, and general practitio-
ners as well as nonmedical professionals as podologists and specialized nurses who
deal with psoriatic nail disease in daily practice, will profi t from this book. The
readers of the book will be able to recognize early signs of the disease, to differenti-
ate them from other nail disorders, to evaluate the severity with validated tools, and
to have a comprehensive overview of all modern therapeutic options in order to treat
their patients or refer them to the specialist, whenever needed.
Athens , Greece Dimitris Rigopoulos , MD
Miami , FL , USA Antonella Tosti , MD
v

Contents
1 Epidemiology of Nail Psoriasis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Bertrand Richert and Marie Caucanas
2 Genetics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9
Martin N. Zaiac, Chantel Amarillo, and Claudia Leon
3 Pathology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15
Eckart Haneke
4 Comorbidities of Nail Psoriasis: From A to Z. . . . . . . . . . . . . . . . . . . 23
Ramya Tripuraneni and Francisco Kerdel
5 Arthritis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Zoe Ash, Sibel Zehra Aydin, Ai Lyn Tan,
and Dennis McGonagle
6 The Clinical Features of Nail Psoriasis . . . . . . . . . . . . . . . . . . . . . . . . 43
Romi Bloom and Antonella Tosti
7 Ultrasound Imaging of Psoriatic Nails. . . . . . . . . . . . . . . . . . . . . . . . . 57
Ximena Wortsman and Rosamary Soto
8 Dermoscopy of Nail Psoriasis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 65
Shailee Patel and Antonella Tosti
9 Severity Evaluation Indexes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73
Dimitrios Rigopoulos and Christos Prevezas
10 Quality of Life . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81
Stamatis Gregoriou and Dimitris Rigopoulos
11 Differential Diagnosis for Nail Psoriasis . . . . . . . . . . . . . . . . . . . . . . . 85
Natalie C. Yin and Antonella Tosti
12 Onychomycosis and Psoriasis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97
Bianca Maria Piraccini, Aurora Alessandrini,
and Carlton Ralph C. Daniel III
13 Treatment of Nail Psoriasis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111
Dimitrios Rigopoulos
vii
viii Contents
14 Nail Psoriasis in Special Populations: Children,
Pregnant, Elderly. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131
Bianca Maria Piraccini and Michela Starace
15 How to Choose My Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 149
Anna Quinn Hare, Julie Jefferson, and Phoebe Rich
16 What Is the Future?. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 157
Dimitris Rigopoulos and Antonella Tosti
Contributors
Aurora Alessandrini , MD Department of Specialized, Experimental
and Diagnostic Medicine , University of Bologna , Bologna , Italy
Chantel Amarillo , MD Herbert Wertheim College of Medicine, Florida
International University , Miami , FL , USA
Zoe Ash , BMedSci, BMBS, MRCP, MD Department of Rheumatology ,
St. Luke’s Hospital, Bradford Teaching Hospitals NHS Foundation Trust ,
Bradford , UK
Sibel Zehra Aydin , MD Department of Rheumatology, Faculty of Medicine ,
Koc University , Istanbul , Turkey
Romi Bloom , BS Department of Dermatology and Cutaneous Surgery ,
University of Miami Leonard M. Miller School of Medicine , Miami , FL , USA
Marie Caucanas , MD Department of Dermatology , Brugmann, St. Pierre
and Queen Fabiola Children’s University Hospitals , Brussels , Belgium
Carlton Ralph C. Daniel III , MD Clinical Professor of Dermatology,
University of Mississippi Medical Center, University of Alabama ,
Birmingham , AL , USA
Stamatis Gregoriou , MD, PhD Department of Dermatology ,
University of Athens Medical School, Attikon Hospital , Athens , Greece
Eckart Haneke , MD, PhD Department of Dermatology , Inselspital,
Univ Hosp Bern , Bern , Switzerland
Anna Quinn Hare , MD Department of Dermatology , Oregon Health
and Science University , Portland , OR , USA
Julie Jefferson , MD Department of Dermatology , Johns Hopkins Medicine ,
Baltimore , MD , USA
Francisco Kerdel , BSc, MBBS Department of Dermatology ,
University of Miami Hospital , Miami , FL , USA
Claudia Leon , MD Florida International University College of Medicine ,
Miami , FL , USA
ix