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Multi-Agent Systems for Healthcare Simulation and Modeling: Applications for System Improvement Raman Paranjape University of Regina, Canada Asha Sadanand University of Guelph, Canada Medical inforMation science reference Hershey • New York Director of Editorial Content: Kristin Klinger Senior Managing Editor: Jamie Snavely Assistant Managing Editor: Michael Brehm Publishing Assistant: Sean Woznicki Typesetter: Jamie Snavely Cover Design: Lisa Tosheff Printed at: Yurchak Printing Inc. Published in the United States of America by Medical Information Science Reference (an imprint of IGI Global) 701 E. Chocolate Avenue Hershey PA 17033 Tel: 717-533-8845 Fax: 717-533-8661 E-mail: [email protected] Web site: http://www.igi-global.com/reference Copyright © 2010 by IGI Global. All rights reserved. No part of this publication may be reproduced, stored or distributed in any form or by any means, electronic or mechanical, including photocopying, without written permission from the publisher. Product or company names used in this set are for identification purposes only. Inclusion of the names of the products or companies does not indicate a claim of ownership by IGI Global of the trademark or registered trademark. Library of Congress Cataloging-in-Publication Data Multi-agent systems for healthcare simulation and modeling : applications for system improvement / Raman Paranjape and Asha Sadanand, editors. p. ; cm. Includes bibliographical references and index. Summary: "This book provides theoretical frameworks and the latest empirical research findings used by medical professionals in the implementation of multi-agent systems"--Provided by publisher. ISBN 978-1-60566-772-0 (hardcover) 1. Artificial intelligence--Medical applications. 2. Intelligent agents (Computer software) I. Paranjape, Raman. II. Sadanand, Asha. [DNLM: 1. Delivery of Health Care--methods. 2. Models, Theoretical. 3. Systems Theory. W 84.1 M961 2010] R859.7.A78M85 2010 610.285'63--dc22 2009021413 British Cataloguing in Publication Data A Cataloguing in Publication record for this book is available from the British Library. All work contributed to this book is new, previously-unpublished material. The views expressed in this book are those of the authors, but not necessarily of the publisher. Editorial Advisory Board Giancarlo Succi, Free University of Bolzano-Bozen, Italy Robert Martens, SaskTel Inc, Canada Yan Yang, NetSecure Technologies Ltd., Canada Craig Gelowitz, TRLabs Inc., Canada Stephen O’Leary, University of British Columbia, Canada Mehran Mehrandezh, University of Regina, Canada List of Reviewers Asha Sadanand, University of Guelph, Canada Maja Hadzic, Curtin University of Technology, Perth, Australia Darshan Dillon, Curtin University of Technology, Perth, Australia Georgiy Bobashev, RTI International, USA Andrei Borshchev, XJ Technologies, Russian Federeation David Isern, Universitat Rovira i Virgili, Spain Antonio Moreno, Universitat Rovira i Virgili, Spain Luigi Benedicenti, University of Regina, Canada Vijay Kumar Mago, DAV College, Jalandhar, Punjab, India Kin Lik Wang, University of Hawaii, Honolulu, USA Nancy E. Reed, University of Hawaii, Honolulu, USA Dale S. Vincent, University of Hawaii, Honolulu, USA Qingjin Peng, University of Manitoba, Canada V. Sadanand, Royal University Hospital, Saskatoon, Saskatchewan, Canada Dean Yergens, University of Manitoba, Canada Xiaoqin (Shelley) Zhang, University of Massachusetts at Dartmouth, USA Simerjit Gill, University of Regina, TRLabs, Canada Raman Paranjape, University of Regina, TRLabs, Canada Table of Contents Foreword .............................................................................................................................................xii Preface ................................................................................................................................................xiv Acknowledgment ................................................................................................................................xvi Section 1 Overview of Healthcare System Issues Chapter 1 Current Practices in Select Healthcare Systems .....................................................................................1 Venkat Sadanand, University of Saskatchewan, Canada Chapter 2 Economic Efficiency and the Canadian Health Care System ...............................................................13 Asha B. Sadanand, University of Guelph, Canada Chapter 3 A Review of Recent Contribution in Agent Based Health Care Modeling ...........................................26 Simerjit Gill, University of Regina, Canada & TRLabs Regina, Canada Raman Paranjape, University of Regina, Canada & TRLabs Regina, Canada Section 2 Healthcare Modeling Systems Chapter 4 Agency in Health Care System Modeling and Analysis .......................................................................45 Raman Paranjape, University of Regina, Canada & TRLabs Regina, Canada Simerjit Gill, University of Regina, Canada & TRLabs Regina, Canada Chapter 5 Operating Room Simulation and Agent-Based Optimization ...............................................................69 Q. Peng, University of Manitoba, Canada Q. Niu, University of Manitoba, Canada Y. Xie, University of Manitoba, Canada T. ElMekkawy, University of Manitoba, Canada Chapter 6 Building a Health Care Multi-Agent Simulation System with Role-Based Modeling .........................90 Xiaoqin Zhang, University of Massachusetts Dartmouth, USA Haiping Xu, University of Massachusetts Dartmouth, USA Bhavesh Shrestha, University of Massachusetts Dartmouth, USA Section 3 Physician/Patient Support Systems Chapter 7 HeCaSe2: A Multi-Agent System that Automates the Application of Clinical Guidelines ................113 David Isern, University Rovira i Virgili, Italy Antonio Moreno, University Rovira i Virgili, Italy Chapter 8 An Agent-Based Modeling System for Wellness ................................................................................137 Luigi Benedicenti, University of Regina, Canada Chitsutha Soomlek, University of Regina, Canada Chapter 9 Using Probabilistic Neural Network to Select a Medical Specialist Agent ........................................164 Vijay Kumar Mago, DAV College, India M. Syamala Devi, Panjab University, India Ajay Bhatia, CTIM&IT, India Ravinder Mehta, Mehta Childcare Center, India Chapter 10 A Multi-Agent Simulation of Kidney Function for Medical Education .............................................178 Kin Lik Wang, University of Hawaii, USA Nancy E. Reed, University of Hawaii, USA Dale S. Vincent, University of Hawaii, USA Section 4 Population Modeling Systems Chapter 11 Role of Multi-Agents System in Creation of Collaborative Environments within Mental Health Domain ....................................................................................................................................196 Maja Hadzic, Curtin University of Technology, Australia Darshan S. Dillon, Curtin University of Technology, Australia Chapter 12 Multi-Agent Systems in Developing Countries ..................................................................................215 Dean Yergens, University of Manitoba, Canada, and University of Calgary, Canada Julie Hiner, University of Calgary, Canada Jörg Denzinger, University of Calgary, Canada Chapter 13 Projecting Health Care Factors into Future Outcomes with Agent-Based Modeling .........................234 Georgiy Bobashev, RTI International, Russia Andrei Borshchev, XJ Technologies, Russia Compilation of References ..............................................................................................................257 About the Contributors ...................................................................................................................276 Index ...................................................................................................................................................282 Detailed Table of Contents Foreword .............................................................................................................................................xii Preface ................................................................................................................................................xiv Acknowledgment ................................................................................................................................xvi Section 1 Overview of Healthcare System Issues Chapter 1 Current Practices in Select Healthcare Systems .....................................................................................1 Venkat Sadanand, University of Saskatchewan, Canada This chapter reviews the current practices of healthcare delivery in three economically advanced countries namely Canada, U.S.A., and U.K. The review shows that medico-legal and technological prowess may not translate into a healthier life and better healthcare delivery. The chapter argues that poor allocation of ample resources is tantamount to resource insufficiency and cites anonymous but true cases of patients to illustrate the salient points. Chapter 2 Economic Efficiency and the Canadian Health Care System ...............................................................13 Asha B. Sadanand, University of Guelph, Canada This chapter examines the compatibility of the objectives of universality and public funding which are two important pillars of the Canadian health care system, with the objectives of cost effectiveness and more generally economic efficiency. Author recommends a market-based mechanism that utilizes mobile agents representing patients and their medical needs. The agents participates in virtual auctions using a needs based ranking as the currency for making bids in order to incorporate the basic goals of universality and public funding. Chapter 3 A Review of Recent Contribution in Agent Based Health Care Modeling ...........................................26 Simerjit Gill, University of Regina, Canada & TRLabs Regina, Canada Raman Paranjape, University of Regina, Canada & TRLabs Regina, Canada This chapter reviews and summarizes eight selected paper in the area of agent-based healthcare systems. The objective of the summaries is to provide an overview of recent research work in the area and to examine the characteristics of agent-based healthcare applications. The chapter also briefly discusses reasons for adopting agent-based simulation and modeling over traditional modeling techniques. Section 2 Healthcare Modeling Systems Chapter 4 Agency in Health Care System Modeling and Analysis .......................................................................45 Raman Paranjape, University of Regina, Canada & TRLabs Regina, Canada Simerjit Gill, University of Regina, Canada & TRLabs Regina, Canada This chapter examines the paradigm that a health care system’s behavior may be examined using an agent simulation in order to illuminate its macroscopic characteristics and the effects of policy on its over all operation. Authors propose the development of a health care system model in which agents mimic the behavior of the key components of the system. These components interact and engage each other in a manor analogous to the operation of the health care system. This chapter present results from the development of a diabetic patient agent model, the development of an agent-based neurosurgery ward bed allocation system, and the development of an agent-based scheduling system that may be used to allocate resources within the health care system. Chapter 5 Operating Room Simulation and Agent-Based Optimization ...............................................................69 Q. Peng, University of Manitoba, Canada Q. Niu, University of Manitoba, Canada Y. Xie, University of Manitoba, Canada T. ElMekkawy, University of Manitoba, Canada This chapter introduces the method of using simulation and agent-based technologies to enable a better understanding of the patient flow to improve the process performance in healthcare. The proposed method is used to identify the existing problem and to evaluate proposed solutions for the problem of the operat- ing room (OR) at Winnipeg Health Sciences Centre. The chapter identifies issues including patient flows, operation schedules, demand and capacity of the system and the configuration of resources required. An optimum scheduling is proposed for the OR operation to shorten the patient waiting time. Chapter 6 Building a Health Care Multi-Agent Simulation System With Role-Based Modeling ........................90 Xiaoqin Zhang, University of Massachusetts Dartmouth, USA Haiping Xu, University of Massachusetts Dartmouth, USA Bhavesh Shrestha, University of Massachusetts Dartmouth, USA This chapter presents an integrated approach for modeling, designing and implementing a multi-agent health care simulation system using Role-based Agent Development Environment (RADE). The chap- ter describes the definition of role classes and agent classes, as well as the automatic agent generation process and also illustrate the coordination problem and present a rule-based coordination approach. In the end, the chapter presents present a runtime scenario of this health care simulation system, which demonstrates that dynamic task allocation can be achieved through the creation of role instances and the mapping from role instances to agents. Section 3 Physician/Patient Support Systems Chapter 7 HeCaSe2: A Multi-Agent System that Automates the Application of Clinical Guidelines ................113 David Isern, University Rovira i Virgili, Italy Antonio Moreno, University Rovira i Virgili, Italy This chapter focuses on the execution of Clinical guidelines (CGs) and describes the design and imple- mentation of an agent-based platform in which the actors involved in health care coordinate their activi- ties to perform the complex task of guideline enactment. Chapter 8 An Agent-Based Modeling System for Wellness ................................................................................137 Luigi Benedicenti, University of Regina, Canada Chitsutha Soomlek, University of Regina, Canada This chapter introduces an agent-based wellness visualization system. The visualization system integrates and analyzes health information collected from existing portable health monitoring devices, users, and other existing health information resources. Authors propose that using the visualization system the individual will have a better understanding in personal wellness and will be encouraged to be aware of both personal and public’s health. The chapter shows initial results that indicate that the proof of concept of the research will provide direct benefits to the public, research communities, and enterprises. Chapter 9 Using Probabilistic Neural Network to Select a Medical Specialist Agent ........................................164 Vijay Kumar Mago, DAV College, India M. Syamala Devi, Panjab University, India Ajay Bhatia, CTIM&IT, India Ravinder Mehta, Mehta Childcare Center, India This chapter presents a novel approach of applying Probabilistic Neural Network (PNN) to classify the childhood disease and their respective medical specialist. The system presented in this chapter imitates the behavior of a pediatrician while selecting super specialist doctor. The aim of this chapter is to design the Multi-agent system, in which the software agents interact with each other to diagnose a disease and decide the treatment plan(s).

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The modeling of healthcare components and systems in order to develop a complete understanding of component interactions is one of the more challenging simulation and modeling problems for software agent systems. Multi-Agent Systems for Healthcare Simulation and Modeling: Applications for System Imp
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