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Campbell Systematic Reviews 2011:6 First published: 29 August, 2011 Last updated: 27 March, 2011 Motivational interviewing for substance abuse Geir Smedslund, Rigmor C. Berg, Karianne T. Hammerstrøm, Asbjørn Steiro, Kari A. Leiknes, Helene M. Dahl, Kjetil Karlsen Please note: Pending reformatting. Colophon Title Motivational interviewing for substance abuse Institution The Campbell Collaboration Authors Geir Smedslund Rigmor C. Berg Karianne T. Hammerstrøm Asbjørn Steiro Kari A. Leiknes Helene M. Dahl Kjetil Karlsen DOI 10.4073/csr.2011.6 No. of pages 128 Last updated 27 March, 2011 Citation Smedslund G, Berg RC, Hammerstrøm KT, Steiro A, Leiknes KA, Dahl HM, Karlsen K. Motivational interviewing for substance abuse. Campbell Systematic Reviews 2011:6 DOI: 10.4073/csr.2011.6 Co-registration This review is co-registered within both the Cochrane and Campbell Collaborations. A version of this review can also be found in the Cochrane Library. Keywords Contributions Karlsen conceived of the idea and commissioned the review. All reviewers were involved in planning the review. Smedslund wrote the methods section of the protocol. Karlsen and Smedslund wrote the background. Hammerstrøm developed the search strategy, performed the original searches and the final search in November 2010. All authors were involved with screening of studies. Smedslund and Berg did the risk of bias and data extraction. Berg and Smedslund graded the results. Smedslund did the analyses and wrote the results and discussion. Support/Funding Norwegian Knowledge Centre for the Health Services, Norway Potential Conflicts None. of Interest Corresponding Geir Smedslund author Norwegian Knowledge Centre for Health Services PB 7004 St. Olavs plass Oslo N-0130 Norway Telephone: +47 2325 5155 / +47 9138 7076 E-mail: [email protected] or [email protected] Campbell Systematic Reviews Editors-in-Chief Mark W. Lipsey, Vanderbilt University, USA Arild Bjørndal, The Centre for Child and Adolescent Mental Health, Eastern and Southern Norway & University of Oslo, Norway Editors Crime and Justice David B. Wilson, George Mason University, USA Education Sandra Wilson, Vanderbilt University, USA Social Welfare William Turner, University of Bristol, UK Geraldine Macdonald, Queen’s University, UK & Cochrane Developmental, Psychosocial and Learning Problems Group Managing Editor Karianne Thune Hammerstrøm, The Campbell Collaboration Editorial Board Crime and Justice David B. Wilson, George Mason University, USA Martin Killias, University of Zurich, Switzerland Education Paul Connolly, Queen's University, UK Gary W. Ritter, University of Arkansas, USA Social Welfare Aron Shlonsky, University of Toronto, Canada Paul Montgomery, University of Oxford, UK Methods Therese Pigott, Loyola University, USA Peter Tugwell, University of Ottawa, Canada The Campbell Collaboration (C2) was founded on the principle that systematic reviews on the effects of interventions will inform and help improve policy and services. C2 offers editorial and methodological support to review authors throughout the process of producing a systematic review. A number of C2's editors, librarians, methodologists and external peer- reviewers contribute. The Campbell Collaboration P.O. Box 7004 St. Olavs plass 0130 Oslo, Norway www.campbellcollaboration.org Motivational interviewing for substance abuse (Review) SmedslundG, Berg RC, Hammerstrøm KT, Steiro A, Leiknes KA, Dahl HM, Karlsen K ThisisareprintofaCochranereview,preparedandmaintainedbyTheCochraneCollaborationandpublishedinTheCochraneLibrary 2011,Issue5 http://www.thecochranelibrary.com Motivationalinterviewingforsubstanceabuse(Review) Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. TABLE OF CONTENTS HEADER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 ABSTRACT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 PLAINLANGUAGESUMMARY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 SUMMARYOFFINDINGSFORTHEMAINCOMPARISON . . . . . . . . . . . . . . . . . . . 2 BACKGROUND . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 OBJECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 METHODS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 RESULTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Figure1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Figure2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Figure3. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Figure4. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Figure5. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Figure6. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 ADDITIONALSUMMARYOFFINDINGS . . . . . . . . . . . . . . . . . . . . . . . . . . 19 DISCUSSION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 AUTHORS’CONCLUSIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 ACKNOWLEDGEMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 CHARACTERISTICSOFSTUDIES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40 DATAANDANALYSES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 Analysis1.1.Comparison1MIversusnointervention,Outcome1Extentofsubstanceuse. . . . . . . . . . 110 Analysis1.2.Comparison1MIversusnointervention,Outcome2Readinesstochange. . . . . . . . . . . 112 Analysis1.3.Comparison1MIversusnointervention,Outcome3Retentionintreatment. . . . . . . . . . 112 Analysis2.1.Comparison2MIversustreatmentasusual,Outcome1Extentofsubstanceuse. . . . . . . . . 113 Analysis2.2.Comparison2MIversustreatmentasusual,Outcome2Retentionintreatment. . . . . . . . . 114 Analysis3.1.Comparison3MIversusassessmentandfeedback,Outcome1Extentofsubstanceuse. . . . . . . 115 Analysis4.1.Comparison4MIversusotheractiveintervention,Outcome1Extentofsubstanceuse. . . . . . . 116 Analysis4.2.Comparison4MIversusotheractiveintervention,Outcome2Readinesstochange. . . . . . . . 117 Analysis4.3.Comparison4MIversusotheractiveintervention,Outcome3Retentionintreatment. . . . . . . 118 APPENDICES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 118 HISTORY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 CONTRIBUTIONSOFAUTHORS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 DECLARATIONSOFINTEREST . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125 SOURCESOFSUPPORT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 126 DIFFERENCESBETWEENPROTOCOLANDREVIEW . . . . . . . . . . . . . . . . . . . . . 126 Motivationalinterviewingforsubstanceabuse(Review) i Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. [InterventionReview] Motivational interviewing for substance abuse GeirSmedslund1,RigmorCBerg1,KarianneTHammerstrøm1,AsbjørnSteiro1,KariALeiknes1,HeleneMDahl2,KjetilKarlsen2 1Norwegian Knowledge Centre for the Health Services, Oslo, Norway. 2Department of Clinical Psychiatry, Institute of Clinical Medicine,Tromsø,Norway Contactaddress:GeirSmedslund,NorwegianKnowledgeCentrefortheHealthServices,Postboks 7004, St.Olavsplass,Oslo,N- 0130,[email protected]. Editorialgroup:CochraneDrugsandAlcoholGroup. Publicationstatusanddate:New,publishedinIssue5,2011. Reviewcontentassessedasup-to-date: 27March2011. Citation: SmedslundG,BergRC,HammerstrømKT,SteiroA,LeiknesKA,DahlHM,KarlsenK.Motivationalinterviewingforsub- stanceabuse.CochraneDatabaseofSystematicReviews2011,Issue5.Art.No.:CD008063.DOI:10.1002/14651858.CD008063.pub2. Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. ABSTRACT Background Thereare76.3millionpeoplewithalcoholusedisordersworldwideand15.3millionwithdrugusedisorders.Motivationalinterviewing (MI)isaclient-centred,semi-directivemethodforenhancingintrinsicmotivationtochangebyexploringandresolvingambivalence. Theinterventionisusedwidely,andthereforeitisimportanttofindoutwhetherithelps,harmsorisineffective. Objectives Toassesstheeffectivenessofmotivationalinterviewingforsubstanceabuseondruguse,retentionintreatment,readinesstochange, andnumberofrepeatconvictions. Searchstrategy Wesearched18electronicdatabases,5websites,4mailinglists,andreferencelistsfromincludedstudiesandreviews.Searchdates wereNovember30,2010forCochraneLibrary,Medline,EmbaseandPsychINFO. Selectioncriteria Randomized controlled trials with persons dependent or abusing substance. Interventions were MI or motivational enhancement therapy.Theoutcomeswereextentofsubstanceabuse,retentionintreatment,motivationforchange,repeatconviction. Datacollectionandanalysis Threeauthorsindependentlyassessedstudiesforinclusion,andtwoauthorsextracteddata.Resultswerecategorizedinto(1)MIversus no-treatmentcontrol,(2)MIversustreatmentasusual,(3)MIversusassessmentandfeedback,and(4)MIversusotheractivetreatment. Withineachcategory,wecomputedmeta-analysesseparatelyforpost-intervention,short,mediumandlongfollow-ups. Mainresults We included 59 studies with a total of 13,342 participants. Compared to no treatment control MI showed a significant effecton substanceusewhichwasstrongestatpost-interventionSMD0.79,(95%CI0.48to1.09)andweakeratshortSMD0.17(95%CI 0.09to0.26],andmediumfollow-upSMD0.15(95%CI0.04to0.25]).Forlongfollow-up,theeffectwasnotsignificantSMD0.06 (95%CI-0.16to0.28).TherewerenosignificantdifferencesbetweenMIandtreatmentasusualforeitherfollow-uppost-intervention, shortandmediumfollowup.MIdidbetterthanassessmentandfeedbackformediumfollow-upSMD0.38(95%CI0.10to0.66). Forshortfollow-up,therewasnosignificanteffect.Forotheractiveinterventiontherewerenosignificanteffectsforeitherfollow-up. TherewasnotenoughdatatoconcludeabouteffectsofMIonthesecondaryoutcomes. Motivationalinterviewingforsubstanceabuse(Review) 1 Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. Authors’conclusions MIcanreducetheextentofsubstanceabusecomparedtonointervention.Theevidenceismostlyoflowquality,sofurtherresearchis verylikelytohaveanimportantimpactonourconfidenceintheestimateofeffectandislikelytochangetheestimate. PLAIN LANGUAGE SUMMARY Motivationalinterviewingisashortpsychologicaltreatmentthatcanhelppeoplecutdownondrugsandalcohol Morethan76millionpeopleworldwidehavealcoholproblems,andanother15millionhavedrugproblems.Motivationalinterviewing (MI)isapsychologicaltreatmentthataimstohelppeoplecutdownorstopusingdrugsandalcohol.Thedrugabuserandcounsellor typicallymeetbetweenoneandfourtimesforaboutonehoureachtime.Thecounsellorexpressesthatheorsheunderstandshowthe clientsfeelabouttheirproblemandsupportstheclientsinmakingtheirowndecisions.Heorshedoesnottrytoconvincetheclientto changeanything,butdiscusseswiththeclientpossibleconsequencesofchangingorstayingthesame.Finally,theydiscusstheclients’ goalsandwheretheyaretodayrelativetothesegoals.Wesearchedforstudiesthathadincludedpeoplewithalcoholordrugproblems andthathaddividedthembychanceintoMIoracontrolgroupthateitherreceivednothingorsomeothertreatment.Weincluded onlystudiesthathadcheckedvideoorsoundrecordingsofthetherapiesinordertobecertainthatwhatwasgivenreallywasMI.The resultsinthisreviewarebasedon59studies.TheresultsshowthatpeoplewhohavereceivedMIhavereducedtheiruseofsubstances morethanpeoplewhohavenotreceivedanytreatment.However,itseemsthatotheractivetreatments,treatmentasusualandbeing assessedandreceivingfeedbackcanbe aseffectiveasmotivational interviewing. Therewasnotenough datatoconclude about the effectsofMIonretentionintreatment,readinesstochange,orrepeatconvictions.Thequalityoftheresearchforcesustobecareful aboutourconclusions,andnewresearchmaychangethem. Motivationalinterviewingforsubstanceabuse(Review) 2 Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. s nt e m m o C e c n e d vi e e h t 1 Qualityof(GRADE) ⊕⊕(cid:13)(cid:13),12low ⊕⊕⊕(cid:13)moderate ⊕⊕(cid:13)(cid:13)1low n] o anati nts pl pa N[Ex Particies) dies) udies) udies) SO Noof(studi 202(4stu 2327(15st 2326(12st I R A P M ct e O eff INC nceabuse Relative(95%CI) GSFORTHEMA atmentcontrolgroupforsubsta abuse ativerisks*(95%CI) Correspondingrisk ontrolmotivationalinterview-ing Themeanamountofsub-stanceabusepostinter-ventionintheinterventiongroupswas0.79standarddeviationshigher(0.48to1.09higher) Themeanamountofsub-stanceabuseshortfol-low-upintheinterventiongroupswas0.17standarddeviationshigher(0.09to0.26higher) Themeanamountofsub-stanceabusemediumfol-low-upintheinterventiongroupswas0.15standarddeviations N tre nce par c SUMMARYOFFINDI motivationalinterviewingcomparedtono Patientorpopulation:patientswithsubstaSettings:Intervention:motivationalinterviewingComparison:notreatmentcontrolgroup OutcomesIllustrativecom Assumedrisk notreatmentgroup amountofsubstanceabusepostintervention amountofsubstanceabuseshortfollow-upFollow-up:1-6months amountofsubstanceabusemediumfollow-upFollow-up:7-12months Motivationalinterviewingforsubstanceabuse(Review) 3 Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. e h t n o d e s a b s i al) v er nt i e c n e d nfi o c ⊕⊕(cid:13)(cid:13),13low ⊕⊕(cid:13)(cid:13),45low ⊕(cid:13)(cid:13)(cid:13),,467verylow sk(andits95% eestimate.getheestimate. ri than g eh n gc rrespondi maychanslikelyto 363(1study) 1495(5studies) 427(2studies) conotes.The ofeffectandofeffectandi foot matemate higher(0.04to0.25higher) amountofsubstanceThemeanamountofsub-abuselongfollow-upstanceabuselongfol-Follow-up:mean12low-upintheinterventionmonthsgroupswas0.06standarddeviationshigher(0.16lowerto0.28higher) ReadinessforchangeThemeanReadinessforchangeintheinterventiongroupswas0.05standarddeviationshigher(0.11lowerto0.22higher) RetentionThemeanRetentionintheFollow-up:0-3monthsinterventiongroupswas0.26standarddeviationshigher(0to0.52higher) assumedrisk*Thebasisforthe(e.g.themediancontrolgroupriskacrossstudies)isprovidedinrelativeeffectassumedriskinthecomparisongroupandtheoftheintervention(andits95%CI).CI:Confidenceinterval; GRADEWorkingGroupgradesofevidenceHighquality:Furtherresearchisveryunlikelytochangeourconfidenceintheestimateofeffect.Moderatequality:FurtherresearchislikelytohaveanimportantimpactonourconfidenceintheestiLowquality:FurtherresearchisverylikelytohaveanimportantimpactonourconfidenceintheestiVerylowquality:Weareveryuncertainabouttheestimate. Unclearrandomisationandblindingofassessor.Confidenceintervalfrom0.48to1.09 1 2 Motivationalinterviewingforsubstanceabuse(Review) 4 Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x ding. xxxx blin xxxx d x n x a x x ment xxxx ositivevalues.ocationconceal xxxxxxxxxxxxxx desbothnegativeandpaaddressed.Unclearall -0.00to0.50. xxxxxxxxxxxxxxxxxxxxx valincluomedat%.%.valfrom xxxxxxx denceintermpleteoutcared=48ared=36denceinter xxxxxxxxxx ConfiIncoI-squI-squConfi xxxxx 3 4 5 6 7 x Motivationalinterviewingforsubstanceabuse(Review) 5 Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd.

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Editors. Crime and Justice David B. Wilson, George Mason University, USA. Education Sandra Wilson, Vanderbilt University, USA. Social Welfare William Turner, of MI William R. Miller or Stephen Rollnick on the author list or motivational enhancement therapy prior to relapse prevention for.
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