Motivational interviewing for substance abuse (Review) SmedslundG, Berg RC, Hammerstrøm KT, Steiro A, Leiknes KA, Dahl HM, Karlsen K ThisisareprintofaCochranereview,preparedandmaintainedbyTheCochraneCollaborationandpublishedinTheCochraneLibrary 2011,Issue5 http://www.thecochranelibrary.com Motivationalinterviewingforsubstanceabuse(Review) Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. TABLE OF CONTENTS HEADER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 ABSTRACT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 PLAINLANGUAGESUMMARY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 SUMMARYOFFINDINGSFORTHEMAINCOMPARISON . . . . . . . . . . . . . . . . . . . 3 BACKGROUND . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 OBJECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 METHODS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 RESULTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 Figure1. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 Figure2. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 Figure3. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 Figure4. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 Figure5. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 16 Figure6. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17 ADDITIONALSUMMARYOFFINDINGS . . . . . . . . . . . . . . . . . . . . . . . . . . 19 DISCUSSION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 AUTHORS’CONCLUSIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 ACKNOWLEDGEMENTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 CHARACTERISTICSOFSTUDIES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 42 DATAANDANALYSES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 111 Analysis1.1.Comparison1MIversusnointervention,Outcome1Extentofsubstanceuse. . . . . . . . . . 112 Analysis1.2.Comparison1MIversusnointervention,Outcome2Readinesstochange. . . . . . . . . . . 114 Analysis1.3.Comparison1MIversusnointervention,Outcome3Retentionintreatment. . . . . . . . . . 115 Analysis2.1.Comparison2MIversustreatmentasusual,Outcome1Extentofsubstanceuse. . . . . . . . . 116 Analysis2.2.Comparison2MIversustreatmentasusual,Outcome2Retentionintreatment. . . . . . . . . 117 Analysis3.1.Comparison3MIversusassessmentandfeedback,Outcome1Extentofsubstanceuse. . . . . . . 118 Analysis4.1.Comparison4MIversusotheractiveintervention,Outcome1Extentofsubstanceuse. . . . . . . 119 Analysis4.2.Comparison4MIversusotheractiveintervention,Outcome2Readinesstochange. . . . . . . . 120 Analysis4.3.Comparison4MIversusotheractiveintervention,Outcome3Retentionintreatment. . . . . . . 121 APPENDICES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 121 WHAT’SNEW . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 HISTORY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 CONTRIBUTIONSOFAUTHORS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 DECLARATIONSOFINTEREST . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 SOURCESOFSUPPORT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 129 DIFFERENCESBETWEENPROTOCOLANDREVIEW . . . . . . . . . . . . . . . . . . . . . 130 INDEXTERMS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 130 Motivationalinterviewingforsubstanceabuse(Review) i Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. [InterventionReview] Motivational interviewing for substance abuse GeirSmedslund1,RigmorCBerg1,KarianneTHammerstrøm1,AsbjørnSteiro1,KariALeiknes1,HeleneMDahl2,KjetilKarlsen2 1Norwegian Knowledge Centre for the Health Services, Oslo, Norway. 2Department of Clinical Psychiatry, Institute of Clinical Medicine,Tromsø,Norway Contactaddress:GeirSmedslund,NorwegianKnowledgeCentrefortheHealthServices,Postboks 7004, St.Olavsplass,Oslo,N- 0130,[email protected]. Editorialgroup:CochraneDrugsandAlcoholGroup. Publicationstatusanddate:Edited(nochangetoconclusions),commentaddedtoreview,publishedinIssue11,2011. Reviewcontentassessedasup-to-date: 27March2011. Citation: SmedslundG,BergRC,HammerstrømKT,SteiroA,LeiknesKA,DahlHM,KarlsenK.Motivationalinterviewingforsub- stanceabuse.CochraneDatabaseofSystematicReviews2011,Issue5.Art.No.:CD008063.DOI:10.1002/14651858.CD008063.pub2. Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. ABSTRACT Background Thereare76.3millionpeoplewithalcoholusedisordersworldwideand15.3millionwithdrugusedisorders.Motivationalinterviewing (MI)isaclient-centred,semi-directivemethodforenhancingintrinsicmotivationtochangebyexploringandresolvingambivalence. Theinterventionisusedwidely,andthereforeitisimportanttofindoutwhetherithelps,harmsorisineffective. Objectives Toassesstheeffectivenessofmotivationalinterviewingforsubstanceabuseondruguse,retentionintreatment,readinesstochange, andnumberofrepeatconvictions. Searchmethods Wesearched18electronicdatabases,5websites,4mailinglists,andreferencelistsfromincludedstudiesandreviews.Searchdates wereNovember30,2010forCochraneLibrary,Medline,EmbaseandPsychINFO. Selectioncriteria Randomized controlled trials with persons dependent or abusing substance. Interventions were MI or motivational enhancement therapy.Theoutcomeswereextentofsubstanceabuse,retentionintreatment,motivationforchange,repeatconviction. Datacollectionandanalysis Threeauthorsindependentlyassessedstudiesforinclusion,andtwoauthorsextracteddata.Resultswerecategorizedinto(1)MIversus no-treatmentcontrol,(2)MIversustreatmentasusual,(3)MIversusassessmentandfeedback,and(4)MIversusotheractivetreatment. Withineachcategory,wecomputedmeta-analysesseparatelyforpost-intervention,short,mediumandlongfollow-ups. Mainresults We included 59 studies with a total of 13,342 participants. Compared to no treatment control MI showed a significant effecton substanceusewhichwasstrongestatpost-interventionSMD0.79,(95%CI0.48to1.09)andweakeratshortSMD0.17(95%CI 0.09to0.26],andmediumfollow-upSMD0.15(95%CI0.04to0.25]).Forlongfollow-up,theeffectwasnotsignificantSMD0.06 (95%CI-0.16to0.28).TherewerenosignificantdifferencesbetweenMIandtreatmentasusualforeitherfollow-uppost-intervention, shortandmediumfollowup.MIdidbetterthanassessmentandfeedbackformediumfollow-upSMD0.38(95%CI0.10to0.66). Forshortfollow-up,therewasnosignificanteffect.Forotheractiveinterventiontherewerenosignificanteffectsforeitherfollow-up. TherewasnotenoughdatatoconcludeabouteffectsofMIonthesecondaryoutcomes. Motivationalinterviewingforsubstanceabuse(Review) 1 Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. Authors’conclusions MIcanreducetheextentofsubstanceabusecomparedtonointervention.Theevidenceismostlyoflowquality,sofurtherresearchis verylikelytohaveanimportantimpactonourconfidenceintheestimateofeffectandislikelytochangetheestimate. PLAIN LANGUAGE SUMMARY Motivationalinterviewingisashortpsychologicaltreatmentthatcanhelppeoplecutdownondrugsandalcohol Morethan76millionpeopleworldwidehavealcoholproblems,andanother15millionhavedrugproblems.Motivationalinterviewing (MI)isapsychologicaltreatmentthataimstohelppeoplecutdownorstopusingdrugsandalcohol.Thedrugabuserandcounsellor typicallymeetbetweenoneandfourtimesforaboutonehoureachtime.Thecounsellorexpressesthatheorsheunderstandshowthe clientsfeelabouttheirproblemandsupportstheclientsinmakingtheirowndecisions.Heorshedoesnottrytoconvincetheclientto changeanything,butdiscusseswiththeclientpossibleconsequencesofchangingorstayingthesame.Finally,theydiscusstheclients’ goalsandwheretheyaretodayrelativetothesegoals.Wesearchedforstudiesthathadincludedpeoplewithalcoholordrugproblems andthathaddividedthembychanceintoMIoracontrolgroupthateitherreceivednothingorsomeothertreatment.Weincluded onlystudiesthathadcheckedvideoorsoundrecordingsofthetherapiesinordertobecertainthatwhatwasgivenreallywasMI.The resultsinthisreviewarebasedon59studies.TheresultsshowthatpeoplewhohavereceivedMIhavereducedtheiruseofsubstances morethanpeoplewhohavenotreceivedanytreatment.However,itseemsthatotheractivetreatments,treatmentasusualandbeing assessedandreceivingfeedbackcanbe aseffectiveasmotivational interviewing. Therewasnotenough datatoconclude about the effectsofMIonretentionintreatment,readinesstochange,orrepeatconvictions.Thequalityoftheresearchforcesustobecareful aboutourconclusions,andnewresearchmaychangethem. Motivationalinterviewingforsubstanceabuse(Review) 2 Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. CoMo SUMMARY OF FINDINGS FOR THE MAIN COMPARISON [Explanation] pyrighttivation ©a 20lin motivationalinterviewingcomparedtonotreatmentcontrolgroupforsubstanceabuse 11ter Tv hie ew Patientorpopulation:patientswithsubstanceabuse Cin og Settings: chfo ranersub ICnotemrpvaernitsioonn::mnoottriveaattimoneanlticnotenrtvrioelwgirnogup Costa llanc boratioeabuse Outcomes Illustrativecomparativerisks*(95%CI) R(9e5la%tivCeI)effect N(sotuodfiePsa)rticipants Q(GuRaAlitDyEo)ftheevidence Comments n.Pu(Rev Assumedrisk Correspondingrisk blisiew h) ed no treatment control motivational interview- b y group ing Jo h n W amount of substance Themeanamountofsub- 202 ⊕⊕(cid:13)(cid:13) iley abusepostintervention stance abuse post inter- (4studies) low1,2 & ventionintheintervention S o n groupswas s , L 0.79standarddeviations td . lower (0.48to1.09higher) amount of substance Themeanamountofsub- 2327 ⊕⊕⊕(cid:13) abuseshortfollow-up stance abuse short fol- (15studies) moderate1 Follow-up:1-6months low-upintheintervention groupswas 0.17standarddeviations lower (0.09to0.26higher) amount of substance Themeanamountofsub- 2326 ⊕⊕(cid:13)(cid:13) abuse medium follow- stanceabusemediumfol- (12studies) low1 up low-upintheintervention Follow-up:7-12months groupswas 0.15standarddeviations 3 CM oo pyrighttivation higher ©a (0.04to0.25higher) 20lin 11ter Thvie amount of substance Themeanamountofsub- 363 ⊕⊕(cid:13)(cid:13) eCwin abuselongfollow-up stance abuse long fol- (1study) low1,3 ochgfo Follow-up: mean 12 low-upintheintervention raneCorsubsta months g0r.0ou6psstawnadsarddeviations llanc lower be oratioabuse h(0ig.1h6er) lower to 0.28 n.Publish(Review) Readinessforchange TchhaenmgeeainnthReeiandteinrevesnstifoonr 1(549s5tudies) ⊕low⊕4(cid:13),5(cid:13) e d groupswas b y Jo 0.05standarddeviations h n higher W ile (0.11 lower to 0.22 y higher) & S o n s, Retention ThemeanRetentioninthe 427 ⊕(cid:13)(cid:13)(cid:13) L td Follow-up:0-3months interventiongroupswas (2studies) verylow4,6,7 . 0.26standarddeviations higher (0to0.52higher) *Thebasisfor theassumedrisk(e.g.themediancontrol groupriskacross studies) isprovidedinfootnotes. Thecorresponding risk(andits95%confidence interval) isbasedonthe assumedriskinthecomparisongroupandtherelativeeffectoftheintervention(andits95%CI). CI:Confidenceinterval; GRADEWorkingGroupgradesofevidence Highquality:Furtherresearchisveryunlikelytochangeourconfidenceintheestimateofeffect. Moderatequality:Furtherresearchislikelytohaveanimportantimpactonourconfidenceintheestimateofeffectandmaychangetheestimate. Lowquality:Furtherresearchisverylikelytohaveanimportantimpactonourconfidenceintheestimateofeffectandislikelytochangetheestimate. Verylowquality:Weareveryuncertainabouttheestimate. 1Unclearrandomisationandblindingofassessor. 2Confidenceintervalfrom0.48to1.09 4 CoMo 3Confidenceintervalincludesbothnegativeandpositivevalues. pyrighttivation 54II-nscqoumapreledte=ou4t8c%om. edataaddressed.Unclearallocationconcealmentandblinding. ©2011alinter 67IC-soqnufiadreendce=in3t6er%va.lfrom-0.00to0.50. Tv heiew xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx Cin og chfo ranersub Costa llanc be oratioabuse n.Pu(Rev blisiew h) e d b y Jo h n W ile y & S o n s , L td . 5 BACKGROUND is a client-centred, semi-directive method for enhancing intrin- sicmotivationtochangebyexploringandresolvingambivalence. MIintegratestherelationship-buildingprinciplesofCarlRogers (Rogers1951)withmoreactivecognitive-behavioural strategies. Descriptionofthecondition The intervention has four basic principles (described below). A AccordingtotheWorldHealthOrganization(WHO2009)there brief variant of MI is called Motivational Enhancement Ther- are76.3millionpeoplewithalcoholusedisordersworldwide.In apy (MET). MET is manual-based, and was developed as part addition, thereare atleast15.3millionpeoplewhosufferfrom of ProjectMATCH (Project MATCH 1997). Project MATCH a drug use disorder, and injecting drug use is reported in 136 wasalargemultisitetrial comparing MIwith cognitive behav- countries. ioraltherapy(CBT)andtwelve-stepfacilitationtherapy.MIcoun- Substanceabusereferstotheoverindulgenceinanddependence sellingdoesnotrequireprofessionaltrainingasnurse,psycholo- onadrugorothersubstanceleadingtoeffectsthataredetrimen- gist,etc.Hence,MImaybeincorporatedinprogrammesrunby taltotheindividual’sphysicalandmentalhealth,orthewelfare healthcarestaffaswellase.g.prisonstaff.Thereareexplicitstan- of others. The disorder is characterized by a pattern of contin- dardsforpractitionersregardingeducationandcompetence,and ued pathological use of a drug or other substance, that results thereisqualitycontroltoensurethatthemethodisinfactused inrepeatedadversesocialconsequencesrelatedtodruguse,such asintended. Oneinstrumentfor assessing treatmentintegrity is as failure to meet work, family, or school obligations, interper- theMotivational Interviewing TreatmentIntegrity (MITI) scale sonalconflicts,orlegalproblems.Thereareon-goingdebatesas (Moyers2005).Foradescriptionofvariousmeasuresoftreatment totheexactdistinctions betweensubstanceabuseandsubstance fidelityinMI,werecommendthereviewbyMadsonandCamp- dependence.Wefollowthedefinitions bytheAmericanPsychi- bell(Madson 2006).Promisingresultshavebeenreportedasto atricAssociation(APA2000)anddistinguishbetweenthetwoby theeffectofthemethodforalcoholdependence,smokingcessa- defining substance dependence as a cluster of cognitive, behav- tion,drugaddiction,HIV-riskbehaviours,treatmentadherence, ioral,andphysiologicalsymptomsindicatingthattheindividual diet&exercise,andeatingdisorders(Carey2007;Burke2004; continuesuseofthesubstancedespitesignificantsubstance-related Hettema2005; Rubak 2005). MI has recentlybeen introduced problems.Thereisapatternofrepeatedself-administrationthat into thecriminal justice system, inEurope aswellasin North- canresultintolerance,withdrawal,andcompulsivedrug-taking America.Intheresearchliterature,themostwidelyusedapproach behavior (APA 2000).Substance abuse isamaladaptive pattern relatedtoMIhasbeenoneinwhichtheclientisgivenfeedback ofsubstance usemanifestedbyrecurrentandsignificant adverse basedonindividualresultsfromstandardizedassessmentmeasures consequencesrelatedtotherepeateduseofsubstances. Inorder oramodificationofit.Burkeetal.(Burke2003)consideredthis foranAbusecriteriontobemet,thesubstance-relatedproblem feedback-basedapproachtoconstitute anadaptation ofmotiva- musthaveoccurredrepeatedlyduringthesame12-monthperiod tionalinterviewing(AMI)becauseitisdefinedbythepresenceof orbeenpersistent. thefeedbackcomponentandnotsolelybytheuseofmotivational Substanceabusemayleadtoaddictionorsubstancedependence. interviewingperse.Morebroadly,theyalsoappliedthetermAMI Medically, physiologic dependence requires the development of tointerventionsthatincorporateadditionalnon-motivationalin- toleranceleadingtowithdrawalsymptoms.Bothabuseanddepen- terviewing techniqueswhileretaining motivational interviewing dencearedistinctfromaddictionwhichinvolvesacompulsionto principlesasthecoreoftreatmentaswellastointerventionsthat continueusingthesubstancedespitethenegativeconsequences, havebeenspecificallyadaptedforusebynon-specialists. andmayormaynotinvolvechemicaldependency(APA2000). Dependence almost always implies abuse, but abuse frequently occurswithoutdependence,particularlywhenanindividualfirst Howtheinterventionmightwork begins toabuse asubstance. Thereisalsoadistinction between “misuse”and“abuse” of substances. Substance misuse isthein- MIisintendedtoworkthroughitsfourmainprinciples:(1)ex- correct use of medication by patients, who may use a drug for press empathy, (2) support self-efficacy,(3) roll with resistance, apurposeotherthanthatforwhichitwasprescribed;oruseof and(4)developdiscrepancy.Asexpressedontheofficialhomepage asubstance for unintended purposes(APA 2000).Thefocus of of Motivational Interviewing (http://motivationalinterview.org/ clinical/principles.html),expressingempathyinvolvesseeingthe thisreviewissubstanceabuse,dependencyoraddiction,butnot worldthroughtheclient’seyes.Supportingself-efficacymeansthat misuse. clientsareheldresponsibleforchoosingandcarryingoutactions tochange.Thethirdprinciple,rollingwithresistance,meansthat thecounsellordoesnotfightclientresistance,but“rollswithit.” Descriptionoftheintervention Statementsdemonstrating resistance are notchallenged.Instead Motivational interviewing (MI) was started by Miller (Miller thecounsellorusestheclient’s“momentum”tofurtherexplorethe 1983)anddevelopedbyMillerandRollnick(Miller1991).MI client’sviews. Lastly,motivation forchangeoccurswhenpeople Motivationalinterviewingforsubstanceabuse(Review) 6 Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. perceiveadiscrepancybetweenwheretheyareandwheretheywant hadnolimitationonlengthofstudy.Weexcludedstudiesthatre- tobe.MIcounsellorsworktodevelopthissituationthroughhelp- cruitedparticipantsinemergencyroomsandprovidedonesession ingclientsexaminethediscrepanciesbetweentheircurrentbehav- ofMIduringthestayintheemergencyroom. iorandfuturegoals.Whenclientsperceivethattheircurrentbe- havioursarenotleadingtowardsomeimportantfuturegoal,they becomemoremotivatedtomakeimportantlifechanges.Apodaca Typesofparticipants andLongabaugh(Apodaca2009)didaliteraturesearchtoidentify Personsdefinedashavingeithersubstanceabuse,dependencyor potentialwithin-sessionmechanismsofchangeinMI.Themost addiction, butnot misuse. There wereno limitations onage or consistentevidencewasfoundforthreeconstructs:clientchange other participant characteristics. The term substance refers to a talk/intention (related to better outcomes); client experience of drugofabuse,amedication,atoxinoralcohol,excludingnico- discrepancy(relatedtobetteroutcomes);andtherapistMI-incon- tine.Thereasonforexcludingnicotine, isthatthereisanexist- sistentbehavior(relatedtoworseoutcomes). ing Cochrane review on motivational interviewing for smoking cessation(Lai2010).AccordingtoInternational classificationof Diseasesversion10(ICD-10)(WHO1993)weincludedthefol- Whyitisimportanttodothisreview lowingcodes,F10toF19*,excludingF15(caffeine)andF17(to- bacco).EquivalentdisordersandcodesintheDiagnosticandSta- Theinterventionisusedwidely,andthereforeitisimportantto tisticalManualofMentalDisorders,thirdrevisededition(DSM- findoutwhetherithelps,harmsorisineffective.Severalreviews III-R) (APA1987)andfourthedition, (DSM-IV)(APA1994), and meta-analyses have been published (e.g. Andreasson 2003; chapterSubstance-Relateddisorders,werealsoincluded.Wealso Burke 2003; Burke 2004; Carey 2007; deWildt 2002; Dunn includedstudiesinwhichsubstanceabusewasnotformallydiag- 2001;Emmelkamp2006;Grenard2006;Hettema2005;Larimer nosed.Participantscouldbedualdiagnosisclients.Weincluded 2007;Lundahl2010;Nahom2005;Rubak2005;Vasilaki2006 bothparticipantswhoonlyabusesubstancesandparticipantswho ) but they all differ somewhat from our review. Some of them alsohavementalproblems,butweanalysedthetwogroupssepa- havestudiedeffectsofMI(AMI)onothergroupsinadditionto rately. substanceabusersorstudiedonlyalcoholabusers.Othersincluded *[Mentalandbehaviouraldisordersduetouseof-alcohol(F10 otherdesignsinadditiontorandomisedtrials.Themainstrengths -303),-opioids(F11),-cannabinoids(F12),-sedativesorhyp- of the present review are that it employs a comprehensive and notics(F13),-cocaine(F14),-otherstimulants(amphetamine) systematic search strategy aiming to be exhaustive, and that it (F15),-hallucinogens(F16),-volatilesolvents(F18)and-mul- includesonlyrandomizedcontrolledtrials.Wewillalsoassessthe tipledruguseanduseofotherpsychoactivesubstances(F19).] riskofbiasoftheincludedstudiesandgradetheevidenceforthe primaryoutcomes. Typesofinterventions Experimentalintervention Primarily,theinterventionsshouldbelabelledmotivationalinter- OBJECTIVES viewing(M))ormotivationalenhancementtherapy(MET).The Toassesstheeffectivenessofmotivationalinterviewing, asapri- interventioncouldbasicallybeofferedinthreeways:(1)asastand- maryorsupportintervention,forsubstanceabuse,intermsoflev- alonetherapy,(2)MIintegratedwithanothertherapy,or(3)MI elsofdruguse,retentionintreatment,andreadinessforchange. asapreludetoanothertherapy(e.g.cognitivebehavioraltherapy). Onlyindividual,face-to-faceinterventionswereincluded.Weex- cludedgroupinterventions, andinterventions notgiveninper- son(e.g.computer-deliveredortelephoneinterventions).Because METHODS mostpsychosocialinterventionshavemanyunspecificelementsin common,andbecausetermslike“motivationalintervention”and “motivationalinterview”notnecessarilyreferstoMiller’sspecific Criteriaforconsideringstudiesforthisreview programofMI,weincludedonlystudiesthatreviewedaudioor videorecordingstoensurethattheinterventiongivenwasindeed MI. Typesofstudies Studieshadtoincludechecksofaudio-orvideotapingofsessions Weincludedstudieswhereunits(persons,therapists,institutions) inordertoassessfidelityoftreatment. wereallocatedrandomlyorquasi-randomlytomotivationalinter- Controlintervention viewingorotherconditions.Includedstudiedhadtobepublished The comparator could be no intervention, waiting list control, inorafter1983,whichwastheyearthatMIwasintroduced.We placebopsychotherapyorotheractivetherapy. Motivationalinterviewingforsubstanceabuse(Review) 7 Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd. Typesofoutcomemeasures substanceabuseandmotivationalinterviewing.TheMEDLINE Dataonsubstanceabusecouldbebothdichotomous(numberof searchstrategywastranslatedintotheotherdatabases using the participantsceasingsubstanceabuse)andcontinuous(e.g.mean appropriatecontrolledvocabularyasapplicable.Thesearchstrate- numberofdaysusedinlast30days).Substanceabusecouldalsobe giesforalldatabasesareshowninAppendix1. measuredusingvariousscalesorinventoriesliketheOTI(Opiate Wesearchedthefollowingwebsitesandmailinglists: TreatmentIndex)(Darke1991;Darke1992),theTimelineFol- Websites: low-Back(Sobell1992),andtheRutgersAlcoholProblemsIndex • www.motivationalinterview.org(bibliographyupdated (RAPI;White1989). November2009) • http://nrepp.samhsa.gov/programfulldetails.asp? PROGRAM_ID=182(accessedJune7th,2010) Primaryoutcomes • http://www.controlled-trials.com(accessedAugust24th, • ceaseofsubstanceusemeasuredbyself-report,reportby 2010) collaterals,urineanalysis,orbloodsamples,etc. • http://clinicalstudyresults.org(accessedAugust24th,2010 • reductioninsubstanceabusemeasuredasabove. • http://centrewatch(accessedAugust24th,2010). Outcomesare typicallyrecorded as aposttest immediately after Mailinglists: theinterventionsended,short-termfollow-upsuntilsixmonths • MINT-listserv;amailinglistavailabletomembersof aftertheinterventionended,medium-termfollow-upsofbetween MINT(MotivationalInterviewingNetworkofTrainers) six and 12 months, and long-term follow-ups of 12 months or • AustralianCriminologyListserv longer.Theexactfollow-updurationsarerecordedforeachstudy. • CampbellCrime&JusticeGroupSteeringCommittee • Crimnet.http://www.law.usyd.edu.au/mailman/listinfo/ Secondaryoutcomes crimnet. • Retentionintreatment. Wehadnolanguagerestrictions. • Improvemotivationforchange,e.g.measuredbythe ReadinesstoChangeQuestionnaire(RCQ;Heather1993). • Numberofrepeatconvictions(forconvictedsubstance Searchingotherresources abusers). Referencesinobtainedreviewsandincludedprimarystudieswere searched(inJune2010)toidentifynewleads. Searchmethodsforidentificationofstudies Datacollectionandanalysis Electronicsearches Dealingwithdependentdata We searched the following electronic databases: Medline (1950 Whentherewasmorethanoneinterventiongroupthatwascom- toNovember Week3, 2010), Embase (1980 to 2010, week4), paredwithasinglecontrolgroup,wedidnotincludebothcom- PsycInfo(1806toNovemberweek4,2010),PsychExtra(1908to parisonsinthesamemeta-analysis.Whentherewereseveralfol- January14,2008),CochraneCentralRegisterofControlledTri- low-uptimes, wecategorisedthemintopost, short,mediumor als(searchdate:November30,2010),C2-SPECTR(Searchdate: longfollow-upasdescribedabove.Incaseswhenthereweredata November23,2009),InternationalBibliographyoftheSocialSci- frommorethanonefollow-uptimewithinoneofourcategories, ences(1951toNovemberweek3,2009), SociologicalAbstracts weusedthemeanvalue.Whentherewasmorethanonemeasure (search date: November 30, 2010), ISI Web of Science (search ofthesameoutcome,weusedthestandardisedmeanvalue. date: November 30, 2010), SveMed+ (search date: November 30,2010),CINCH(searchdate:November30,2010),NCJRS Selectionofstudies (searchdate:November30,2010),SpringerLink(searchdate:Oc- tober2,2010),WileyInterscience(searchdate:October2,2010), The screening of studies proceededin 3 levels.At Level 1, two DrugScopeLibrary(searchdate:October2,2010),ElectronicLi- reviewerswhoweremethodologistsscannedthetitlesofeachref- braryoftheNationalDocumentationCentreonDrugUse(search erence.Eachreviewerscoredeither“promotetonextlevel”,“ex- date:October2,2010),GoogleScholar,andGoogle(searchdate: clude”or“can’ttell”.Onlyifbothreviewersscored“exclude”was February2,2010). Yearofpublicationwaslimitedto1983and thereferenceexcluded.Ifatleastonereviewerscored“can’ttell” later. or“include”,thereferencewaspromotedtoLevel2.AtLevel2, Databases were searched using a strategy developed incorporat- thetitlesandabstractswereread,andthesamepromotionrules ingthefilterfortheidentificationofRCTs(Higgins2009)com- applied.ReferencespromotedtoLevel3wereorderedinfulltext. binedwith selectedMeSHtermsandfreetexttermsrelating to Tworeviewersreadthefulltextsandscored“include”or“exclude”. Motivationalinterviewingforsubstanceabuse(Review) 8 Copyright©2011TheCochraneCollaboration.PublishedbyJohnWiley&Sons,Ltd.
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