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Molecular Immunology 1993: Vol 30 Table of Contents PDF

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Molecular Immunology LIST OF CONTENTS AND AUTHOR INDEX FOR VOLUME 30, 1993 © Pergamon Press Oxford - New York - Seoul - Tokyo Molecular Immunology Board of Regional Editors Prof. MICHEL FOUGEREAU (Chairman of the Board), Centre d'/mmunologie de Marseille -Luminy, Case 906, 13288 Marseille Cedex 9, France Dr JANNIE BORST, Division of Cellular Biochemistry, The Netherlands Cancer Institute, Plesmanilaan 121, 1066 CX Amsterdam, The Netherlands Dr STEVE DOWER, /mmunex Corporation, 51 University Street, Seattle, WA 98101, U.S.A. Dr STEVE GERONDAKIS, The Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Victoria 3050, Australia Dr DAVID HOLOWKA, Department of Chemistry, Cornell University, Ithaca, NY 14853, U.S.A. Dr ED PALMER, Base/ /nstitute for Immunology, Grenzacherstrasse 487, CH -4005, Basel, Switzerland Dr HIDDE PLOEGH, Massachusetts Institute of Technology, Center for Cancer Research, 40 Ames Street, E17-322, Cambridge, MA 02139, U.S.A. Founding Editor Prof. DAN H. CAMPBELL Advisory Editors G. |. ABELEV ARNOLD FROESE EDUARDO A. PADLAN Moscow, Russia Winnipeg, Canada Bethesda, MD, U.S.A. B. H. BARBER C. GRANIER ISRAEL PECHT Toronto, Canada Montpellier, France Rehovot, /srae/ DAVID H. BING SEN-ITIROH HAKOMORI JEAN-LOUIS PREUD’HOMME Boston, MA, U.S.A. Seattle, WA, U.S.A. Poitiers, France C. A. BONA JOHN K. INMAN EVA RAJNAVOLGY! New York, NY, U.SA. Bethesda, MD, U.S.A. God, Hungary GUY BORDENAVE DAVID ISENMAN J. V. RAVETCH Paris, France Toronto, Canada New York, NY, U.SA. DENNIS R. BURTON M. KAARTINEN KENNETH H. ROUX San Diego, CA, U.SA. Helsinki, Finland Tallahassee, FL, U.SA. L. WILLIAM CLEM JEAN-PIERRE KINET D. J. ROWLANDS Jackson, MI, U.SA. Bethesda, MD, U.S.A. London, U.K. JOHN E. COLIGAN MICHEL KLEIN CATHERINE SAUTES Bethesda, MD, U.SA. Toronto, Canada Paris, France MAURICE COLOMB D. M. KRANZ VERNE N. SCHUMAKER Grenoble, France Urbana, IL, U.SA. Los Angeles, CA, U.SA. D. H. CONRAD M. P. LEFRANC DAVID M. SEGAL Richmond, VA, U.S.A. Montpellier, France Bethesda, MD, U.SA. GIAMPIETRO CORRADIN WARREN J. LEONARD B. DAVID STOLLAR Lausanne, Switzerland Bethesda, MD, U.S.A. Boston, MA, U.S.A. M. DAERON HENNING LOWENSTEIN MARC VAN REGENMORTEL Paris, France Horsholm, Denmark Strasbourg, France M. P. DIERICH J. P. MACH EDWARD W. VOSS, JR Innsbruck, Austria Epalinges, Switzerland Urbana, IL, U.S.A. DOUGLAS FEARON DAVID G. MARSH |. YAHARA Cambridge, U.K. Baltimore, MD, U.S.A. Tokyo, Japan Z. FISHELSON SHERIE L. MORRISON JUNJI YODOI Tel Aviv, /srae/ Los Angeles, CA, U.SA. Kyoto, Japan R. FRADE JIR|I NOVOTNY D. C. YUAN Paris, France Princeton, NJ, U.S.A. Dallas, TX, U.SA. Production Editor VICTORIA McNEILL, Pergamon Press Ltd, Oxford OX3 OBW, England. Te/. 0865 743871. Publishing and Advertising Offices: Pergamon Press Ltd, Headington Hill Hall, Oxford OX3 OBW, U.K., and Pergamon Press Inc., 660 White Plains Road, Tarrytown, NY 10591-5153, U.S.A. Annual Institutional Subscription Rates 1994: North, Central and South America, U.S.$1255.00, Rest of World £814.00. Associated Personal Subscription Rates are available on request for those whose institutions are library subscribers. Sterling prices exclude VAT. Non-VAT registered customers in the European Community will be charged the appropriate VAT in addition to the price listed. Prices include postage and insurance and are subject to change without notice. Subscription enquiries from customers in North America should be sent to: Pergamon Press Inc., 660 White Plains Road, Tarrytown, NY 10591-5153, U.S.A., and for the remainder of the world to: Pergamon Press Ltd, Headington Hill Hall, Oxford OX3 OBW, U.K. Published monthly plus additional issues in February, April, June, August, October and December. Copyright © 1993 Pergamon Press Ltd Whilst every effort is made by the publishers and editorial board to see that no inaccurate or misleading data, opinion or statement appear in this journal, they wish to make it clear that the data and opinions appearing in the articles and advertisements herein are the sole responsibility of the contributor or advertiser concerned. Accordingly, the publishers, the editorial board and editors and their respective employees, officers and agents accept no responsibility or liability whatsoever for the consequences of any such inaccurate or misleading data, opinion or statement. Second Class Postage paid at Rahway, NJ and additional mailing offices. Postmaster send address corrections to Mo/ecular /mmunology, c/o Pergamon Press Inc., 660 White Plains Road, Tarrytown, NY 10591-5153, U.S.A. List of Contents and Author Index for Volume 30, 1993 CONTENTS OF VOLUME 30 NUMBER ONE D. Kozbor, E. Hyjek, Competitor mRNA fragments for quantitation of cytokine R. Wiaderkiewicz, Z. Wang, specific transcripts in cell lysates M. Wang and E. Loh R. Attanasio, P. Kanda, G. W. Stunz, Anti-peptide reagent identifies a primary-structure-depen- D. W. Buck and R. C. Kennedy dent, cross-reactive idiotype expressed on heavy and light chains from a murine monoclonal anti-CD4 K. R. Chintalacharuvu, M. E. Lamm Unstable inter-H chain disulfide bonding and non- and C. S. Kaetzel covalently associated J chain in rat dimeric IgA D. H. Conrad, C. A. Kozak, Chromosomal location and isoform analysis of mouse J. Vernachio, C. M. Squire, Fe, Ril/CD23 M. Rao and E. M. Eicher T. E. Michaelsen, L. M. Neess Human IgG3 is decreased and IgG1, IlgG2 and IgG4 are and A. Aase unchanged in molecular size by mild reduction and reoxidation without any major change in effector functions T. L. McInerney, G. J. Howlett, Quantitative analysis of the interaction between lysozyme L. C. Gruen and D. C. Jackson and monoclonal antibody D1.3 A. Alcover, F. Hervé, J.-P. Boursier, A soluble form of the human CD8 alpha chain expressed G. Spagnoli, D. Olive, R. A. Mariuzza in the baculovirus system: biochemical characterization and and O. Acuto binding to MHC class | G. Tosi, G. Mantero, A. R. Magalini, HLA-DQB1 typing of north east Italian IDDM patients D. Primi, M. Soffiati, L. Pinelli, using amplified DNA, oligonucleotide probes and a rapid S. Sartoris, G. Tridente and DNA-enzyme immunoassay (DEIA) R. S. Accolla J. Sawada, T. Yamazaki and T. Terao Molecular and biochemical analyses of combining sites of monoclonal anti-morphine antibodies N. F. Rebbe, B. D. Tong Expression of nucleotide pyrophosphatase and alkaline and S. Hickman phosphodiesterase | activities of PC-1, the murine plasma cell antigen M. Dupuis, M. C. Peitsch, U. Hamann, Mutations in the putative lipid-interaction domain of K. K. Stanley and J. Tschopp complement C9 result in defective secretion of the functional protein Short Communications Y. K. Sykulev, R. J. Cohen Particle counting by flow cytometry can determine intrinsic and H. N. Eisen equilibrium constants for antibody—ligand interactions in solution S. Angal, D. J. King, M. W. Bodmer, A single amino acid substitution abolishes the hetero- A. Turner, A. D. G. Lawson, geneity of chimeric mouse/human (lgG4) antibody G. Roberts, B. Pedley and J. R. Adair Brief Structural Data Reports M. J. Atkinson and G. E. Wu Genomic sequence of a V(D)J rearrangement utilizing a new VH7183 family member VH7183.15 IV List of Contents and Author Index for Volume 30, 1993 N. Harindranath, G. Donadel, 111 Comparison of complete nucleotide sequence of the human G. Sigounas and A. L. Notkins IgM heavy chain constant region of polyreactive and monoreactive antibodies NUMBER TWO V. Koistinen 113 Effects of sulphated polyanions on _ functions of complement factor H M. Adib-Conquy, S. Avrameas and 119 Monoclonal IgG and IgM autoantibodies obtained after T. Ternynck polyclonal activation, show reactivities similar to those of polyclonal natural autoantibodies M.-B. Villiers, F. M. Gabert, 129 Involvement of the Zn-binding region of tetanus toxin in B M. R. Jacquier, C. L. Villiers and and T recognition. Influence of Zn fixation M. G. Colomb Q. V. Nguyen, A. M. Roskey, 137 Effects of Brefeldin A on cleavage of invariant chain to p21 and R. E. Humphreys and p10 and the appearance of |;-freed class || MHC dimers G. Zeder-Lutz, D. Altschuh, 145 Monoclonal antipeptide antibodies: affinity and kinetic rate H. M. Geysen, E. Trifilieff, constants measured for the peptide and the cognate protein G. Sommermeyer and using a biosensor technology M.H. V. Van Regenmortel N. Paul-Eugene, J. P. Kolb, 157 Functional interaction between f,-adrenoceptor agonists A. Calenda, J. Gordon, H. Kikutani, and interleukin-4 in the regulation of CD23 expression and T. Kishimoto, J. M. Mencia-Huerta, release and IgE production in human P. Braquet and B. Dugas J. Rothe, H. Bluethmann, 165 Genomic organization and promoter function of the murine R. Gentz, W. Lesslauer and tumor necrosis factor receptor f gene M. Steinmetz S. Takahashi, J. Itoh, M. Nose, 177 Cloning and cDNA sequence analysis of nephritogenic M. Ono, T. Yamamoto and monoclonal antibodies derived from an MRL/Ipr lupus M. Kyogoku mouse M. Taniai, T. Kayano, R. Takakura, 183 Epitopes on Cry/ | and Cry/ || for the human IgE antibodies S. Yamamoto, M. Usui, S. Ando, cross-reactive between Cupressus sempervirens and M. Kurimoto, R. Panzani Cryptomeria japonica pollen and T. Matuhasi J. Lederer and C. Czuprynski 191 Characterization and_ identification § of interleukin-1 receptors on bovine fibroblasts Review N. Ilsakov 197 Tyrosine phosphorylation and dephosphorylation in T lymphocyte activation NUMBER THREE U. R. Nilsson, K.-E. Storm, 211 Conformational epitopes of C3 reflecting its mode of H. Elwing and B. Nilsson binding to an artificial polymer surface List of Contents and Author Index for Volume 30, 1993 V V. Bichko, F. Schddel, M. Nassal, 221 Epitopes recognized by antibodies to denatured core E. Gren, |. Berzinsh, G. Borisova, protein of hepatitis B virus S. Miska, D. L. Peterson, E. Gren, P. Pushko and H. Will J. D. Pound, J. Lund and R. Jefferis Aglycosylated chimaeric human |IgG3 can trigger the human phagocyte respiratory burst P. Wilkins Stevens, C. H. Francis, Monoclonal antibodies to HIV-1 p24 core protein include M. E. Jolley and D. R. Bethell pairs which exhibit synergistic binding M.M. Newkirk, J. Rauch, Restricted immunoglobulin variable region gene usage by R. A. K. Mageed, R. Jefferis, hybridoma rheumatoid factors from patients with systemic D. N. Posnett and G. J. Silverman lupus erythematosus and rheumatoid arthritis M. Tomana, J. Zikan, Z. Moldoveanu, Interactions of cell-surface galactosyltransferase with R. Kulhavy, J. C. Bennett immunoglobulins and J. Mestecky M. Tomana, J. Zikan, R. Kulhavy, Interactions of galactosyltransferase with serum and J. C. Bennett and J. Mestecky secretory immunoglobulins and their component chains E. A. Armandola, S. M. Mariani Serological and molecular characterization of mouse anti- and S. Ferrone idiotypic monoclonal antibodies elicited with the syngeneic anti-HLA-A2,28 monoclonal antibody CR11-351 Choong-Eun Lee, Suk-Ran Yoon and Mechanism of interferon-y down-regulation of the inter- Kwang-Ho Pyun leukin 4-induced CD23/Fc,RIl expression in human B cells: post-transcriptional modulation by interferon-y R. J. Boackle, M. H. Connor and High molecular weight non-immunoglobulin — salivary J. Vesely agglutinins (NIA) bind C1Q globular heads and have the potential to activate the first complement component E. L. LaCroix and A. Froese The N-linked oligosaccharides of the Fce receptors of rat basophilic leukemia cells Erratum NUMBER FOUR J. H. Wu, A. Herp and A. M. Wu 333 Defining carbohydrate specificity of Ricinus communis agglutinin as GalB1—-4GIcNAc (11) > Galf1— 3GIicNAc (1) > Gala1-+3Gal (B) > Galf1-— 3GalNAc (T) R. C. Williams, Jr, C. C. Malone Conformational dependency of human IgG heavy chain- and A. Solomon associated Gm allotypes V. Brinkmann, J. S. Remington Vaccination of mice with the protective F3G3 antigen of and S. D. Sharma Toxoplasma gondii activates CD4* but not CD8"* T cells and induces toxoplasma specific IgG antibody D. P. Cerretti, C. J. Kozlosky, Molecular characterization of receptors for human inter- T. Vanden Bos, N. Nelson, leukin-8, GRO/melanoma growth-stimulatory activity and D. P. Gearing and M. P. Beckmann neutrophil activating peptide-2 R. |. Near, M. Mudgett-Hunter, Characterization of an anti-digoxin antibody binding site by J. Novotny, R. Bruccoleri site-directed jn vitro mutagenesis and S. C. Ng VI List of Contents and Author Index for Volume 30, 1993 J. K. Batra, S. Kasturi, M. G. Gallo, 379 Insertion of constant region domains of human IgG, into R. L. Voorman, S. M. Maio, CD4-PE40 increases its plasma half-life V. K. Chaudhary and |. Pastan . Sarrowa and L. A. Steiner 387 Primary structure of Xenopus /aevis S10, a ribosomal pro- i tein that cross-reacts with antibodies to immunoglobulin light chains George, K. M. Sheehan, 395 Junctional diversification in the generation of the precursor US H. Brodeur and J. L. Claflin of a discrete immune response D. B. Rubinstein, M. Symann, 403 Restriction fragment length polymorphisms and _ single A. K. Stewart and T. Guillaume germline coding region sequence in VH18/2, a duplicated gene encoding autoantibody F. Piskurich, J. A. France, 413 Interferon-y induces polymeric immunoglobulin receptor . M. Tamer, C. A. Willmer, mRNA in human intestinal epithelial cells by a protein QO. 0S.¢ Kaetzel and D. M. Kaetzel synthesis dependent mechanism NUMBER FIVE S. Roman-Roman, L. Ferradini, 423 Alternatively spliced T cell receptor transcripts expressed in O. Azogui, F. Faure, T. Hercend human T lymphocytes and F. Triebel M. G. Wing, D. J. Seilly, 433 Rapid isolation and biochemical characterization of rat C1 D. J. Bridgman and R. A. Harrison and Ciq L. Cuomo, P. Trivedi, 441 Selective induction of allostimulatory capacity after 5-azaC P. Otavio de Campos-Lima, treatment of EBV carrying but not EBV negative Burkitt Quian-Jin Zhang, E. Ragnar, lymphoma cell lines G. Klein and M. G. Masucci D. L. Cassel, M. A. Keller, S. Surrey, 451 Differential expression of FcyRIIA, FcyRIIB and FcyRIIC in E. Schwartz, A. D. Schreiber, hematopoietic cells: analysis of transcripts E. F. Rappaport and S. E. McKenzie K . Okamura, H. Ishiguro, 461 Comparison of nucleotide sequences from upstream of the Y. Ichihara and Y. Kurosawa Dos2 gene to the Su region of immunoglobulin heavy-chain gene loci between Suncus murinus, mouse and human D. Pound, J. Lund and 469 Human FcyRI triggering of the mononuclear phagocyte . Jefferis respiratory burst » J. Liu, R. Sen and T. L. Rothstein 479 Abnormal x B-binding protein in the cytoplasm of a plasma- cytoma cell line that lacks nuclear expression of NF-«B E. F. Rosloniec, K. S. Beard 491 Functional analysis of the antigen binding region of an and J. H. Freed MHC class II molecule K. Mabrouk, M. Moulard, 503 Evaluation of structure—antigenicity relationship of peptides J. C. Gluckman, R. Romi, H. Rochat, from human immunodeficiency virus type 1 (HIV-1) p18 J. Van Rietschoten and E. Bahraoui protein by circular dichroism 513 Book Reviews List of Contents and Author Index fOT Volume 39, 1993 NUMBER SIX E. Paz-Artal, A. Corell, P. Varela, 515 New DNA S€quences for the human complement gene C4 P. Morales, J. M. M. Villa, O. G. Segurado, M. Alvarez and A. A. Villena J. Hunyadi, A. S. Kenderessy, 517 Platelet-act!vating factor antagonists (BN 52021 and E. Duda, P. Braquet and A. Dobozy BN 50730) inhibit tumor necrosis factor-alfa-mediated cytotoxicitY On myrine L929 tumor cells A. Hohmann, V. Peters, R. Comacchio 521 Mouse MO"OClonaj anti-idiotypic antibodies to HIV p24: and J. Bradley immunocheMica] properties and internal imagery J. Galea-Lauri, J. Blackford and 529 The expression of CD11/CD18 molecules on rabbit leuco- J. M. Wilkinson cytes: ident'fication of monoclonal antibodies to CD18 and their effect ©Nn celjyjar adhesion processes M. Friede, S. Muller, J.-P. Briand, 539 Induction of immune response against a short synthetic M.H. V. Van Regenmortel peptide aMtigen coupled to small neutral liposomes and F. Schuber containing ™Onophosphory! lipid A S. Mécheri, G. Dannecker, D. Dennig, 549 Anti-histoP® autoantibodies react specifically with the B P. Poncet and M. K. Hoffmann cell surface B. L. Rogers, J. P. Morgenstern, 559 Recombinant Fe/ ¢ |: expression, purification, |gE binding R. D. Garman, J. F. Bond and M. Kuo and reactiO" With cat-allergic human T cells G. S. Kelner, M. K. Jenkins and 569 A single a™'!No acid substitution in a cytochrome c T cell R. Jemmerson Stimulatory Peptide changes the MHC restriction element from one !SOtype (|-A*) to another (1-E*) C. Pinilla, J. R. Appel and 577 Functional 'Mportance of amino acid residues Making up R. A. Houghten peptide antigenic determinants G. Bushell, C. Nelson, H. Chiu, 587 Evidence SYPPportinga role for cathepsin B in the generation C. Grimley, W. Henzel, J. Burnier of T cell aMtigenic epitopes of human growth hormone and S. Fong W. Tao, F. Hardardottir and 593 Extensive SOMatic mutation in the lg heavy chain V genes A. L. M. Bothwell in a late PF'Mary anti-hapten immune response B. Shopes 603 A genetically engineered human IgG with limited flexibility fully initiates Cytolysis via Complement 611 Announce™Ments NUMBER SEVEN C. Leclerc, E. Dériaud, F. Megret, 613 IdentificatiON of helper T cell epitopes of dengue virus J.-P. Briand, E-protein M.H. V. Van Regenmortel and V. Deubel P. Garrone and J. Banchereau 627 Agonistic ®Md antagonistic effects of cholera toxin on human B l¥Mphocyte proliferation S. B. Easterbrook-Smith 637 A light-scattering method for measuring the sizes of insoluble '™mune complexes M. A. Lee, E. Bengtén, 641 CharacteriS@tion of rainbow trout cDNAs encoding a A. Daggfeldt, A. Rytting and secreted 8" membrane-bound Ig heavy chain and the L. Pilstrom genomic iMtron upstream of the first constant exon Vill List of Contents and Author Index for Volume 30, 1993 P. Morel, C. Vincent, J. Wijdenes and 649 Internalization and degradation of anti-CD4 monoclonal J. P. Revillard antibodies bound to human peripheral blood lymphocytes B. F. Flanagan, N. J. Wheatcroft, 659 T cell receptor junctional regions of Vy9*/V52* T cell S. M. Thornton and S. E. Christmas clones in relation to non-MHC restricted cytotoxic activity C. G. Garlisi, K. J. Pennline, 669 Cytokine gene expression in mice undergoing chronic S. R. Smith, M. |. Siegel graft-versus-host disease and S. P. Umland A. Sahu and M. K. Pangburn 679 Identification of multiple sites of interaction between heparin and the complement system N. W. Hudson, M. Albrecht, 685 Regeneration of antidigoxin binding activity in an antibody Z. |. Randhawa, L. K. Steinrauf and by changes surrounding the original binding defect J. A. Hamilton L. Morelli, L. Plotkin, J. Leoni, 695 Analysis of oligosaccharides involved in the asymmetrical C. A. Fossati and R. A. Margni glycosylation of IgG monoclonal antibodies NUMBER EIGHT W. S. Jewell, L. L. Marnell, 701 C-reactive protein (CRP) binding to the Sm-D protein of L. A. Rokeach and T. W. Du Clos snRNPS. Identification of a short polypeptide binding region J. D. Pauls, S. M. Edworthy 709 Epitope mapping of histone 5 (H5) with systemic lupus and M. J. Fritzler erythematosus, procainamide-induced lupus and hydrala- zine-induced lupus sera B. L. Talken, U. Tummuru 721 Slow egress of a mouse MHC class | molecule to the cell and D. R. Lee surface despite its strong association with £,-microglobulin J.-P. Y. Scheerlinck, R. DeLeys, 733 Redistribution of a murine humoral immune response E. Saman, L. Brys, A. Geldhof following removal of an immunodominant B cell epitope and P. De Baetselier from a recombinant fusion protein J. Lund, N. Takahashi, H. Nakagawa, 741 Control of |lgG/Fc glycosylation: a comparison of oligosac- M. Goodall, T. Bentley, S. A. Hindley, charides from chimeric human/mouse and mouse subclass R. Tyler and R. Jefferis immunoglobulin Gs J. F. Elliott, C. L. Miller, B. Pohajdak, 749 Induction of a proteoglycan core protein mRNA in mouse D. Talbot, C. D. Helgason, T lymphocytes R. C. Bleackley and V. Paetkau A. Hoeveler and B. Malissen 755 The cysteine residues in the cytoplasmic tail of CD8« are required for its coreceptor function J. P. Reeves and S. L. Epstein 765 Recombinant human CD4 elicits antibody responses differ- ent in epitope specificity from those that cellular CD4 elicits Y. G. Alevy, J. Tucker, B. Naziruddin 775 CD32C (FcyRIIC) mRNA expression and regulation and T. Mohanakumar Brief Structural Data Report W. R. Hein and L. Dudler 783 Nucleotide sequence of the membrane form of sheep IgM and identification of two Cy allotypes 785 Addendum List of Contents and Author Index for Volume 30, 1993 NUMBER NINE J. D. Mountz and M. A. Subler 787 Regulation of c-myb oncogene expression in immature and mature murine T cells T. Frey, P. Estess and V. T. Oj 797 Dimerization of CD4-C, chimeric molecules leads to loss of CD4 epitopes G. Froyen, |. Ronsse and A. Billiau 805 Bacterial expression of a single-chain antibody fragment (SCFV) that neutralizes the biological activity of human interferon-y D. Stickney, R. L. Mosley, 813 T cell receptor delta gene repertoire and diversity of M. Whetsell, L. Whetsell, intestinal intraepithelial lymphocytes in athymic mice F. V. Schaefer, K. S. Miller and J. R. Klein M. Z. Whitley, Hwei-Ling Cheng, 821 Distinct IL-4 response mechanisms of the MHC gene Aa in T. B. Tomasi and M. Boothby different mouse B cell lines M.M. Barry and J. S. Lee 833 Cloning and expression of an autoimmune DNA-binding single chain Fv. Only the heavy chain is required for binding M. Okada, A. Kojima, H. Takano, 841 Functional properties of the allotypes of mouse comp- Y. Harada, M. Nonaka, M. Nonaka, lement regulatory protein, factor H: difference of compati- T. Kinoshita, T. Seya and bility of each allotype with human factor | S. Natsuume-Sakai Z. Végh, P. Wang, F. Vanky Increased expression of MHC class | molecules on human and E. Klein cells after short time IFN-y treatment NUMBER TEN C. A. Rey-Millet, S. Chesne and 855 Associated complement C3b. Towards an understanding of M. G. Colomb its intracellular modifications C. Vandevyver, M. Steukers, 865 Development and _ functional characterization of a J. Lambrechts, H. Heyligen murine/human chimeric antibody with specificity for the and J. Raus human interleukin-2 receptor E. Champagne, A. Hucheng, J. Sevin, An alternative method for T-cell receptor repertoire analysis: N. Casteran and B. Rubin clustering of human V-beta subfamilies selected in responses to staphylococcal enterotoxins B and E A. Ya. Chernyak, A. Weintraub, The f-configuration of the rhamnosidic linkage in N. K. Kochetkov and A. A. Lindberg Salmonella serogroups C, and C, lipopolysaccharide is important for the immunochemistry of the O-antigen 8 M. Kazemi, C. C. Huntenburg Lipopolysaccharide epitope specificity and binding cross and J. E. Bubbers reactivity of the human IgM anti-lipid A monoclonal antibody SdJ5-1.17.15 C. Boyer, S. Ley, A. Davies Comparative analysis of phosphotyrosy! polypeptides in and M. Crumpton normal and leukemic human T lymphocytes activated via CD3 or CD2 D. Askew, C. J. Burger and 911 Tumor-induced modulation of macrophage class I| MHC K. D. Elgert molecule mRNA expression Xx List of Contents and Author Index for Volume 30, 1993 A. Terskikh, J.-P. Mach and 921 Marked increase in the secretion of a fully antigenic A. Pélegrin recombinant carcinoembryonic antigen obtained by deletion of its hydrophobic tail P. B. Armstrong, M. T. Armstrong 929 Involvement of «,-macroglobulin and C-reactive protein and J. P. Quigley in a complement-like hemolytic system in the arthropod, Limulus polyphemus R. Nezlin, A. Freywald and 935 Proteins separated from human IgG molecules M. Oppermann H. Deulofeut, A. Iglesias, N. Mikael, 941 Cellular recognition and HLA restriction of a midsequence D. H. Bing, Z. Awdeh, J. Yunis, HBsAg peptide in hepatitis B vaccinated individuals D. Marcus-Bagley, M. S. Kruskall, C. A. Alper and E. J. Yunis Viewpoint E. W. Voss, Jr 949 Significance and properties of the autoanti-metatype immune response Short Communications U. Settmacher, S. Jahn, P. Siegel, 953 An anti-lipid A antibody obtained from the human fetal R. von Baehr and A. Hansen repertoire is encoded by V,,6-V,1 genes J. L. Pellequer and 955 Affinity of monoclonal antibodies to large multivalent anti- M. H. V. Van Regenmortel gens: influence of steric hindrance on antibody affinity constants calculated from Scatchard plots 959 Announcement NUMBER ELEVEN . M. Shaw, C. M. Stanley, 961 Influence of the T-helper epitope on the titre and affinity . D. Partidos and M. W. Steward of antibodies to B-cell epitopes after co-immunization . N. Kasturi, C. Daian, Y. Saitoh, 969 Tight-skin mouse autoantibody repertoire: analysis of V,, Muryoi and C. A. Bona and V, gene usage 4Om xO Brandt, F. Petersen and H.-D. Flad 979 A novel molecular variant of the neutrophil-activating peptide NAP-2 with enhanced biological activity is truncated at the C-terminus: identification by antibodies with defined epitope specificity . Meshcheryakova, S. Andreev, 993 CD4-derived peptide and sulfated polysaccharides have . Tarasova, M. Sidorova, M. Vafina, similar mechanisms of anti-HIV activity based on electro- . Kornilaeva, E. Karamov and static interactions with positively charged gp120 fragments . Khaitov DAW . OMH.” NOW eidner, L. K. Denzin, 1003 Elicitation of distinct populations of monoclonal antibodies M.L. Kim, W. D. Mallender, specific for the variable domains of monoclonal anti-fluor- S. D. Miklasz and E. W. Voss, Jr escein antibody 4-4-20 D. J. Panka, D. L. Very, 1013 Defining the structural correlates responsible for loss of B. A. Jacobson, P. H. Kussie, arsonate affinity in an Id°* antibody isolated from an B. Parhami-Seren, M. N. Margolies autoimmune mouse and A. Marshak-Rothstein P. Fuschiotti, N. Harindranath, 1021 Recombination activating genes-1 and -2 of the rabbit: R. G. Mage, W. T. McCormack, cloning and characterization of germline and expressed P. Dhanarajan and K. H. Roux genes

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