Table Of Content

BB. Molecular Basis of Disease Vol. 1182, 1993 Cumulative Contents Review The functions of thrombospondin and its involve- genetic mechanism in inborn errors of meta- ment in physiology and pathophysiology bolism J. Lahav (Israel) A. Boneh and G. Bach (Israel) 64 Substratum acidification and proteinase activa- Regular Papers tion by murine B16F10 melanoma cultures P.R. Young and S.M. Spevacek (USA) 69 Identification of two new LDL-receptor muta- Redox metabolism of vitamin C in blood of nor- tions causing homozygous familial hyper- mal and malaria-infected mice cholesterolemia in a South African of Indian E.N. Iheanacho, R. Stocker and N.H. Hunt (Australia) 15 origin D.C. Rubinsztein, I. Jialal, E. Leitersdorf, G.A. Relationships among alterations in renal mem- Coetzee and D.R. Van der Westhuyzen (South brane sodium transport, renin and aminopepti- Africa, USA, Israel) 75 dase M activities in genetic hypertension S. Salardi, R. Falchetto, C. Troffa, P. Parenti, Pseudomonal elastase injection causes low vascu- lar resistant shock in guinea pigs B.R. Barber, S. Pastore, N. Glorioso and G. Bianchi (Italy, Switzerland) 22 M.M. Hossain Khan, T. Yamamoto, H. Araki, Y. [jiri, Y. Shibuya, M. Okamoto and T. Kam- Tangier disease: isolation and characterization of bara (Japan) 83 LpA-I, LpA-II, LpA-I: A-II and LpA-IV parti- Effects of monoclonal antibodies on a-staphy- cles from plasma lotoxin action against erythrocytes and model P. Duchateau, D. Rader, N. Duverger, N. Theret, phospholipid membranes C. De Geitere, H.B. Brewer Jr., J.C. Fruchart O.V. Krasilnikov, V.I. Ternovsky, P.G. Merzliak, and G.R. Castro (France, USA) 30 L.T. Zachidova and K.-D. Hungerer (Uzbekis- Pan-sulfation of bile salts markedly increases hy- tan, Germany) 94 drophilicity and essentially abolishes self- and The O, generating oxidase of B lymphocytes: hetero-association with lecithin Epstein-Barr virus-immortalized B lympho- J.M. Donovan, I.M. Yousef and M.C. Carey (USA, Canada) 37 cytes as a tool for the identification of defec- tive components of the oxidase in chronic Albumin Hawkes Bay; a low level variant caused granulomatous disease by loss of a sulphydryl group at position 177 S.O. Brennan and A.P. Fellowes (New Zealand) 46 F. Morel, L. Cohen Tanugi Cholley, G. Bran- dolin, A.C. Dianoux, C. Martel, P. Cham- Cross-reactivity between murine melanoma anti- pelovier, J.M. Seigneurin, P. Francois, M. Bost gen B700 and a human melanoma-associated and P.V. Vignais (France) 101 antigen (M-66) recognized by autologous anti- body: evidence suggesting shared epitopes A. Toporowicz, D.M. Gersten, V.J. Hearing, Rapid Reports W.E. Brown and D.R. Vlock (USA) 51 Production of macrophage colony-stimulating factor (M-CSF) by human articular cartilage and Amyloid formation by salmon calcitonin chondrocytes. Modulation by interleukin-1 and P.J. Gilchrist and J.P. Bradshaw (UK) 111 tumor necrosis factor a Oxygen-dependent reduction of a nitroxide free I.K. Campbell, G. Ianches and J.A. Hamilton radical by electron paramagnetic resonance (Australia) 57 monitoring of circulating rat blood Inhibition of protein kinase C activity in mucol- V. Quaresima, C.L. Ursini, G. Gualtieri, A. Sot- ipidosis type-4: a model for a new patho- giu and M. Ferrari (Italy) 115 340 Minireview Plasminogen activators and plasminogen activator inhibitors in connective tissues and connective Recent developments in certain X-linked genetic tissue cells: influence of the neuropeptide sub- eye disorders stance P on expression B.S. Shastry (USA) 119 P.G. Murphy and D.A. Hart (Canada) 205 Calpain activity alters in rat myocardial subfrac- Regular Papers tions after ischemia or reperfusion K.-i. Yoshida, Y. Yamasaki and S.-i. Kawashima Elevated serum a-fetoprotein level of nude mice (Japan) 215 bearing hepatoma cells by treatment with Pancreatic islet cells are highly susceptible to- monoclonal antibodies to a-fetoprotein wards the cytotoxic effects of chemically gener- K. Masuda, S. Nagata, K. Hirano, Y. Takagishi ated nitric oxide and H. Hirai (Japan) 128 K.-D. Kroncke, H.-H. Brenner, M.-L. Rodriguez, Polyamines in testosterone-induced hypertrophic K. Etzkorn, E.A. Noack, H. Kolb and V. Kolb- and antifolate-induced hyperplastic mouse kid- Bachofen (FRG) 221 ney. Differential effect of a-difluoromethyl- ornithine Editorial U M. Manteuffel-Cymborowska, W. Chmurzynska and B. Grzelakowska-Sztabert (Poland) 133 Minireview Molecular basis of an adult form of Sandhoff disease: Substitution of glutamine for arginine Lacticacidemia at position 505 of the B-chain of B-hexosa- B.H. Robinson (Canada) 231 minidase results in a labile enzyme P.A. Bolhuis, N.J. Ponne, H. Bikker, F. Baas Regular Papers and J.M.B. Vianney de Jong (The Netherlands) 142 Ceramide composition of the psoriatic scale Pedigree analysis of a-L-fucosidase gene muta- S. Motta, M. Monti, S. Sesana, R. Caputo, S. tions in a fucosidosis family Carelli and R. Ghidoni (Italy) 147 M. Yang, H. Allen and R.A. DiCioccio (USA) — 245 Renal corticosterone 6B-hydroxylase in the spon- Delayed oxidation of intramitochondrial pyridine taneously hypertensive rat nucleotide oxidoreduction state as compared S. Ghosh, W. McLean Grogan, A. Basu and C. with tissue oxygenation in human liver trans- Watlington (USA) 152 plantation Structural and functional studies in vitro on the A. Tanaka, T. Kitai, §S. Iwata, K. Hirao, A. p6 protein from the HIV-1 gag open reading Tokuka, B. Sato, N. Yanabu, S. Mori, T. Ino- frame moto, Y. Yamaoka, K. Tanaka, K. Ozawa and D. Stys, I. Blaha and P. Strop (Czechoslovakia) 157 B. Chance (Japan, USA) 250 A carbon-13 nuclear magnetic resonance investi- Identification of hybrid-type carbohydrate chains gation of the metabolic fluxes associated with on the light chain of human monoclonal anti- glucose metabolism in human erythrocytes body specific to lung adenocarcinoma M.C. Schrader, C.J. Eskey, V. Simplaceanu and H. Tachibana, K. Seki and H. Murakami (Japan) 257 C. Ho (USA) 162 Co-overexpression of bacterial GroESL chaper- Measurement of fluxes through the pentose phos- onins partly overcomes non-productive folding phate pathway in erythrocytes from individuals and tetramer assembly of E. coli-expressed with sickle cell anemia by carbon-13 nuclear human medium-chain acyl-CoA dehydroge- magnetic resonance spectroscopy nase (MCAD) carrying the prevalent disease- M.C. Schrader, V. Simplaceanu and C. Ho causing K304E mutation (USA) 179 P. Bross, B.S. Andresen, V. Winter, F. Kréutle, Fibronectin fragments bind to and penetrate car- T.G. Jensen, A. Nandy, S. Kglvraa, S. Ghisla, L. tilage tissue resulting in proteinase expression Bolund and N. Gregersen (Denmark, Germany) 264 and cartilage damage Pore formation by a two-component leukocidin D.-l. Xie and G.A. Homandberg (USA) 189 from Staphylococcus aureus within the mem- Biological distribution of ?°"Tc-labeled YIGSR brane of human polymorphonuclear leukocytes and IKVAV laminin peptides in rodents: V. Finck-Barbancon, G. Duportail, O. Meunier »°mTc-IKVAV peptide localizes to the lung and D.A. Colin (France) 275 P.O. Zamora, D. Eshima, D. Graham, L. Shat- Use of the hemagglutinating virus of Japan tuck and B.A. Rhodes (USA) (HVJ)-liposome method for analysis of infil- trating lymphocytes induced by hepatitis B E. Consolmagno, R. Leoncini, M. Pizzichini, E. virus gene expression in liver tissue Marinello, M. Rubino and R. Pagani (Italy) K. Kato, Y. Dohi, Y. Yoneda, K.-i. Yamamura, Tissue distribution of succinylacetone in the rat Y. Okada and M. Nakanishi (Japan) in vivo: a possible basis for neurotoxicity in Alterations of peroxisomal function in ischemia- hereditary infantile tyrosinemia reperfusion injury of rat kidney P.A. Wyss, S. Boynton, J. Chu and K.S. Roth S. Gulati, L. Ainol, J. Orak, A.K. Singh and I. (USA, Switzerland) Singh (USA) Rapid Reports Differences in 27-hydroxycholesterol concentra- tions in plasma and liver of baboons with high Low extracellular magnesium induces intracellu- and low responses to dietary cholesterol and lar free Mg deficits, ischemia, depletion of fat high-energy phosphates and cardiac failure in S.Q. Hasan and R.S. Kushwaha (USA) intact working rat hearts: A °!P-NMR study Recombinant murine serum amyloid A from B.M. Altura, R.L. Barbour, T.L. Dowd, F. Wu, baculovirus-infected insect cells: purification B.T. Altura and R.K. Gupta (USA) and characterization Infrared spectroscopic characterisation of multi- B. Kluve-Beckerman, M. Song, M.D. Benson ple sclerosis plaques in the human central ner- and J.J. Liepnieks (USA) vous system Analysis of glyoxalase-I from normal and tumor L.-P. Choo, M. Jackson, W.C. Halliday and tissue from human colon H.H. Mantsch (Canada) S. Ranganathan and K.D. Tew (USA) The behavior of free purine nucleotides in lym- Cumulative Contents phocytes infected with HIV-1 virus A. Tabucchi, F. Carlucci, M.C. Re, G. Furlini, Author Index