Table Of Content

Molecular and Cellular Biochemistry: An International Journal for Chemical Biology in Health and Disease CONTENTS VOLUME 256/257, Nos. 1 & 2, January (II)/February 2004 BIOENERGETICS OF THE CELL: ORGANIZED METABOLIC SYSTEMS Drs. Valdur A. Saks, Renée Ventura-Clapier, Michel Rigoulet, Frank N. Gellerich and Xavier Leverve V.A. Saks, R. Ventura-Clapier, M. Rigoulet, F.N. Gellerich and X. Leverve: Preface Part I — Cellular Metabolic Systems: Organization, compartmentation and metabolic channeling J. Ovadi and V. Saks: On the origin of intracellular compartmentation and organized metabolic systems P.P. Dzeja, A. Terzic and B. Wieringa: Phosphotransfer dynamics in skeletal muscle from creatine kinase gene-deleted mice R. Ventura-Clapier, A. Kaasik and V. Veksler: Structural and functional adaptations of striated muscles to CK deficiency F. Joubert, P. Mateo, B. Gillet, J.-C. Beloeil, J.-L. Mazet and J.A. Hoerter: CK flux or direct ATP transfer: Versatility of energy transfer pathways evidenced by NMR in the perfused heart E. Janssen, J. Kuiper, D. Hodgson, L.V. Zingman, A.E. Alekseev, A. Terzic and B. Wieringa: Two structurally distinct and spatially compartmentalized adenylate kinases are expressed from the AKI gene in mouse brain M. Rigoulet, H. Aguilaniu, N. Avéret, O. Bunoust, N. Camougrand, X. Grandier-Vazeille, C. Larsson, 1.L. Pahlman, S. Manon and L. Gustafsson: Organization and regulation of the cytosolic NADH metabolism in the yeast Saccharomyces cerevisiae J. Ovadi, F. Orosz and S. Hollan: Functional aspects of cellular microcompartmentation in the development of neurodegeneration: Mutation induced aberrant protein-protein associations 83-93 P.W. Hochachka and Y. Burelle: Control of maximum metabolic rate in humans: Dependence on performance phenotypes 95-103 Part Il — Mitochondrial Outer Membrane-Intermembrane Compartment: Role in the cellular regulation M. Colombini: VDAC: The channel at the interface between mitochondria and the cytosol 107-115 M. Vyssokikh and D. Brdiczka: VDAC and peripheral channelling complexes in health and disease 117-126 S.V. Lemeshko and V.V. Lemeshko: Energy flux modulation on the outer membrane of mitochondria by metabolically-derived poten- tial B. Antonsson: Mitochondria and the Bcl-2 family proteins in apoptosis signaling pathways P. Dos Santos, M.N. Laclau, S. Boudina and K.D. Garlid: Alterations of the bioenergetics systems of the cell in acute and chronic myocardial ischemia Part III — Regulation of Cellular Energy Metabolism: Quantitative aspects of structure-function relationship in health and pathology M.A. Aon, B. O’Rourke and S. Cortassa: The fractal architecture of cytoplasmic organization: Scaling, kinetics and emergence in metabolic networks 169-184 V.A. Saks, A.V. Kuznetsov, M. Vendelin, K. Guerrero, L. Kay and E.K. Seppet: Functional coupling as a basic mechanism of feedback regulation of cardiac energy metabolism 185-199 E.V. Liimatta, A. Gédecke, J. Schrader and I.E. Hassinen: Regulation of cellular respiration in myoglobin-deficient mouse heart 201-208 J. Jacobson and M.R. Duchen: Interplay between mitochondria and cellular calcium signalling 209-218 E.K. Seppet, M. Eimre, T. Andrienko, T. Kaambre, P. Sikk, A.V. Kuznetsov and V. Saks: Studies of mitochondrial respiration in muscle cells in situ: Use and misuse of experimental evidence in mathematical modelling 219-227 M. Vendelin, M. Eimre, E. Seppet, N. Peet, T. Andrienko, M. Lemba, J. Engelbrecht, E.K. Seppet and V.A. Saks: Intracellular diffusion of adenosine phosphates is locally restricted in cardiac muscle 229-241 V.A. Selivanov, A.E. Alekseev, D.M. Hodgson, P.P. Dzeja and A. Terzic: Nucleotide-gated K,,,, channels integrated with creatine and adenylate kinases: Amplification, tuning and sensing of energetic signals in the compartmentalized cellular environment 243-256 M.K. Aliev and A.N. Tikhonov: Random walk analysis of restricted metabolite diffusion in skeletal myofibril systems 257-266 B. N’Guessan, J. Zoll, F. Ribera, E. Ponsot, E. Lampert, R. Ventura-Clapier, V. Veksler and B. Mettauer: Evaluation of quantitative and qualitative aspects of mitochondrial function in human skeletal and cardiac muscles 267-280 D. Pucar, P.P. Dzeja, P. Bast, R.J. Gumina, C. Drahl, L. Lim, N. Juranic, S. Macura and A. Terzic: Mapping hypoxia-induced bioenergetic rearrangements and metabolic signaling by 'SO-assisted *'P NMR and 'H NMR spectroscopy 281-289 L. Kadaja, K.E. Kisand, N. Peet, U. Braun, K. Metskiila, K. Teesalu, R. Vibo, K.V. Kisand, R. Uibo, H. Jockusch and E.K. Seppet: IgG from patients with liver diseases inhibit mitochondrial respiration in permeabilized oxidative muscle cells: Impaired function of intracellular energetic units? 291-303 F. Streijger, C.R. Jost, F. Oerlemans, B.A. Ellenbroek, A.R. Cools, B. Wieringa and C.E.E.M. Van der Zee: Mice lacking the UbCKmit isoform of creatine kinase reveal slower spatial learning acquisition, diminished exploration and habituation, and reduced acoustic startle reflex responses J.G. Sampedro and S. Uribe: Trehalose-enzyme interactions result in structure stabilization and activity inhibition. The role of viscosity Part IV — Dynamics and Heterogeneity of Cellular Energy Metabolism D.A. Rube and A.M. van der Bliek: Mitochondrial morphology is dynamic and varied V.P. Skulachev, L.E. Bakeeva, B.V. Chernyak, L.V. Domnina, A.A. Minin, O.Y. Pletjushkina, V.B. Saprunova, I.V. Skulachev, V.G. Tsyplenkova, J.M. Vasiliev, L.S. Yaguzhinsky and D.B. Zorov: Thread-grain transition of mitochondrial reticulum as a step of mitoptosis and apoptosis A.V. Kuznetsov, Y. Usson, X. Leverve and R. Margreiter: Subcellular heterogeneity of mitochondrial function and dysfunction: Evidence obtained by confocal imaging 359-365 C. Ojeda, P. Joseph, V.A. Saks, V. Piriou and Y. Tourneur: Subcellular heterogeneity in mitochondrial red-ox responses to K sp Channel 367-377 agonists in freshly isolated rabbit cardiomyocytes G. Landgraf, F.N. Gellerich and M.H.P. Wussling: Inhibitors of SERCA and mitochondrial Ca-uniporter decrease velocity of calcium waves in rat cardiomyocytes 379-386 H. Podhaisky and M.H.P. Wussling: The velocity of calcium waves is expected to depend non-monotoneously on the density of the calcium release units 387-390 F.N. Gellerich, S. Trumbeckaite, T. Miiller, M. Deschauer, Y. Chen, Z. Gizatullina and S. Zierz: Energetic depression caused by mitochondrial dysfunction 391-405 O. Speer, L.J. Neukomm, R.M. Murphy, E. Zanolla, U. Schlattner, H. Henry, R.J. Snow and T. Wallimann: Creatine transporters: A reappraisal 407-424 Index to Volume 256/257 Instructions to Authors KElecltrounic wjouernarls (at niinn?eé Contact your librarian for more information