Models of seizures and epilepsy

691 Pages·2006·19.668 MB·English

by  Asla Pitkänen, P A Schwartzkroin, Solomon L Moshé

Contributing Authors
Massimo Avoli, Department of Neurology and Neuro- mental, Universidade Federal de Sao Paulo, Sao Paulo,
surgery, McGill University, Montreal, Canada Brazil
Roy A. Bakay, Department of Neurological Surgery, Wei-Ping Chen, Department of Physiology and Pharma-
Chicago Institute of Neurosurgery and Neuroresearch, cology, SUNYHealth Science Center, Brooklyn, NY
Rush Presbyterian-St. Luke’s Medical Center, Chicago, IL
Suzanne Clark, Department of Biomedical Science,
Scott C. Baraban, Department of Neurological Surgery, Colorado State University, Fort Collins, CO
University of California San Francisco, San Francisco, CA
Miguel A. Cortez, Department of Neurology, Hospital for
Tallie Z. Baram, Departments of Pediatrics and Anatomy Sick Children, Toronto, Ontario, Canada
and Neurobiology, University of California Irvine, Irvine,
Marco de Curtis, Department of Experimental Neurophys-
CA
iology, Instituto Nazionale Neurologico Carlo Besta,
Stefania Bassanini, National Neurological Institute Carlo Milan, Italy
Besta, Milan, Italy
Antoine Depaulis, Université Joseph Fourier, Grenoble,
Giorgio Battaglia, National Neurological Institute Carlo France
Besta, Milan, Italy
Marc A. Dichter, Department of Neurology, University
Christophe Bernard, INMED-INSERM U29, Marseilles,
of Pennsylvania School of Medicine, Philadelphia,
France
PA
Edward H. Bertram, Department of Neurology, University
Céline Dinocourt, Department of Physiology, University of
of Virginia, Charlottesville, VA
Maryland, Baltimore, MD
Ronald A. Browning, Department of Physiology, Southern
Céliné M. Dubé, Department of Anatomy and Neuro-
Illinois University School of Medicine, Springfield, IL
biology, University of California Irvine, Irvine, CA
Paul S. Buckmaster, Department of Comparative Medi-
F. Edward Dudek, Department of Physiology, University
cine, Stanford University, Stanford, CA
of Utah, Salt Lake City, UT
Daniel L. Burgess, Department of Neurology, Baylor
Jerome Engel, Jr., Reed Neurological Research Center,
College of Medicine, Houston, TX
Department of Neurology, UCLA School of Medicine,
Thomas Budde, Institut fur Physiologie, Otto-von- Los Angeles, CA
Guericke-Universitat, Universitatsklinikum, Magdeburg,
Aristea S. Galanopoulou, Departments of Neurology and
Germany
Neuroscience, Albert Einstein College of Medicine,
Xiang Cai, Department of Physiology, University of Mary- Bronx, NY
land, Baltimore, MD
Mary E. Gilbert, Neurotoxicology Division, US Environ-
Esper A. Cavalheiro, Escola Paulista de Medicina mental Protection Agency, Research Triangle Park,
(UNIFESP/EPM), Laboratorio de Neurologia Experi- NC
xi
xii Contributing Authors
Jeffrey H. Goodman, Center for Neural Recovery and Joseph J. LoTurco, Department of Physiology and Neuro-
Rehabilitation Research, Helen Hayes Hospital, West biology, University of Connecticut, Storrs, CT
Haverstraw, NY
Heiko J. Luhmann, Institut fur Physiologie und Patho-
Ali Gorji, Institut fur Physiologie, Universitat Munster, physiologie, Johannes-Gutenberg-Mainz Universitat,
Munster, Germany Mainz, Germany
Heidi Grabenstatter, Department of Biomedical Science, Gilles van Luijtelaar, Department of Biological Psychol-
Colorado State University, Fort Collins, CO ogy, Radboud University of Nijmegen, Nijmegen, The
Netherlands
Kevin D. Graber, Department of Neurology and Neuro-
logical Sciences, Stanford University, Stanford, CA Pavel Maresˇ, Institute of Physiology, Academy of Sciences,
Videnska, Prague, Czech Republic
Uwe Heinemann, Institute of Neurophysiology, Charite,
Humboldt University, Berlin, Germany Gary W. Mathern, Department of Neurological Surgery,
Gregory L. Holmes, Dartmouth Medical School, University of California Los Angeles, Los Angeles, CA
Dartmouth-Hitchcock Medical Center, Lebanon, NH
Andrey M. Mazarati, University of California Los
John R. Huguenard, Department of Neurology and Neu- Angeles, West Los Angeles VA Medical Center, Los
rological Sciences, Stanford University, Stanford, CA Angeles, CA
John G.R. Jefferys, Department of Neurophysiology, Uni- Tracy K. McIntosh, Traumatic Brain Injury Laboratory,
versity of Birmingham Medical School, Birmingham, Department of Neurosurgery, University of Pennsylvania,
United Kingdom Philadelphia, PA
Frances E. Jensen, Department of Neurology, Children’s Dan C. McIntyre, Department of Psychology, Carleton
Hospital, Harvard Medical School, Boston, MA University, Ottawa, Ontario, Canada
Phillip C. Jobe, Biomedical and Therapeutic Sciences, Uni- James O. McNamara, Department of Neurobiology, Duke
versity of Illinois College of Medicine, Peoria, IL University Medical Center, Durham, NC
OliverKann, Institute of Neurophysiology, Charite, Hum- Luiz E. Mello, Department of Physiology, Universidade
boldt University, Berlin, Germany Federal de Sao Paulo, Sao Paulo, Brazil
Kevin M. Kelly, Department of Neurology, Allegheny- Solomon L. Moshé, Departments of Neurology,
Singer Research Institute, Allegheny General Hospital, Neuroscience and Pediatrics, Albert Einstein College of
Pittsburgh, PA Medicine, Montefiore Medical Center, Bronx, NY
Irina Kharatishvilli, Department of Neurobiology, AI Maria G. Naffah-Mazzacoratti, Escola Paulista de
Virtanen Institute for Molecular Science, University of Medicina (UNIFESP/EPM), Laboratorio de Neurologia
Kuopio, Kuopio, Finland Experimental, Universidade Federal de Sao Paulo, Sao
Paulo, Brazil
Rüdiger Köhling, University of Rostock, Institute of
Physiology, Rostock, Germany Astrid Nehlig, Faculty of Medicine, University of Stras-
Hana Kubová, Institute of Physiology, Academy of bourg, Strasbourg, France
Sciences, Videnska, Prague, Czech Republic Prosper N’Gouemo, Department of Pharmacology,
Sanjay S. Kumar, Department of Comparative Medicine, Georgetown University Medical Center, Washington, DC
Stanford University, Stanford, CA
Jari Nissinen, Department of Neurobiology, AI Virtanen
João P. Leite, Department of Neurology, Universidade Institute for Molecular Sciences, University of Kuopio,
Federal de Sao Paulo, Sao Paulo, Brazil Kuopio, Finland
Laura Librizzi, Department of Experimental Neurophysi- Jeffrey L. Noebels, Developmental Neurogenetics Labora-
ology, Instituto Nazionale Neurologico Carlo Besta, tory, Department of Neurology, Baylor College of
Milan, Italy Medicine, Houston, TX
Dean D. Lin, Brain Institute, Department of Neurological Michael W. Nestor, Department of Physiology, University
Surgery, University of Florida, Gainesville, FL of Maryland, Baltimore, MD
Wolfgang Löscher, Department of Pharmacology, Toxicol- Andre Obenaus, Department of Radiation Medicine,
ogy & Pharmacy, School of Veterinary Medicine, Radiobiology Program, Loma Linda University, Loma
Hannover, Germany Linda, CA
Contributing Authors xiii
Jeffrey Ockuly, Department of Neurology, University of O. Carter Snead III, Department of Neurology, The
Wisconsin, Madison, WI Hospital for Sick Children, Toronto, Ontario, Canada
Hans-Christian Pape, Institut fur Physiologie, Otto-von- Erwin-Josef Speckmann, Institut fur Physiologie, Univer-
Guericke-Universitat, Universitatsklinikum, Magdeburg, sitat Munster, Munster, Germany
Germany
Ajay Srivastava, Department of Pharmacology & Toxicol-
Asla Pitkänen, Department of Neurobiology, AI Virtanen ogy, Anticonvulsant Drug Development Program, Uni-
Institute for Molecular Sciences, University of Kuopio, versity of Utah, Salt Lake City, UT
Kuopio, Finland
Carl E. Stafstrom, Department of Neurology, University of
John Pollard, Department of Neurology, University of Wisconsin, Madison, WI
Pennsylvania School of Medicine, Philadelphia, PA
Mark Stewart, Department of Physiology and Pharmacol-
David A. Prince, Department of Neurology and Neurolog- ogy, SUNYHealth Science Center, Brooklyn, NY
ical Sciences, Stanford University, Stanford, CA
Janet L. Stringer, Department of Pharmacology, Baylor
Dominick P. Purpura, Dean, Albert Einstein College of
College of Medicine, Houston, TX
Medicine, Bronx, NY
Lucie Suchomelova, University of California Los Angeles,
Raddy L. Ramos, Department of Physiology and Neurobi-
West Los Angeles VA Medical Center, Los Angeles,
ology, University of Connecticut, Storrs, CT
CA
Charles E. Ribak, Department of Anatomy and Neurobiol-
Thomas P. Sutula, Departments of Neurology and
ogy, University of California Irvine, Irvine, CA
Anatomy, University of Wisconsin Medical School,
Michael A. Rogawski, Epilepsy Research Section, Porter Madison, WI
Neuroscience Research Center, National Institute of
Kerry W. Thompson, University of California Los
Neurological Disorders and Stroke, Bethesda, MD
Angeles, West Los Angeles VA Medical Center, Los
Steven N. Roper, Brain Institute, Neurological Surgery, Angeles, CA
University of Florida, Gainesville, FL
Scott M. Thompson, Department of Physiology, University
Russell M. Sanchez, Department of Pharmacology, Uni- of Maryland, Baltimore, MD
versity of Texas Health Science Center, San Antonio, TX
William J. Triggs, Department of Neurology, College of
Raman Sankar, Departments of Neurology and Pediatrics, Medicine, University of Florida, Gainesville, FL
Brain Research Institute, University of California Los
Yuto Ueda, Department of Psychiatry, Miyazaki Medical
Angeles, Los Angeles, CA
College, Miyazaki, Japan
Sebastian Schuchmann, Institute of Neurophysiology,
Laura Uva, Department of Experimental Neurophysiology,
Charite, Humboldt University, Berlin, Germany
Instituto Nazionale Neurologico Carlo Besta, Milan,
Philip A. Schwartzkroin, Department of Neurological Italy
Surgery, University of California Davis, Davis, CA
Libor Velísˇek, Departments of Neurology and Neuro-
Laszlo Seress, Central Electron Microscopic Laboratory, science, Albert Einstein College of Medicine, Bronx, NY
Faculty of Medicine, University of Pecs, Pecs, Szigeti,
Hungary Jana Velísˇková, Departments of Neurology and Neuro-
science, Albert Einstein College of Medicine, Bronx, NY
Lee A. Shapiro, Department of Anatomy and Neurobiology,
University of California Irvine, Irvine, CA Matthew C. Walker, Institute of Neurology, University
College London, London, UK
Yukiyoshi Shirasaka, University of California Los Angeles,
West Los Angeles VA Medical Center, Los Angeles, Claude Wasterlain, Brain Research Institute, University of
CA California Los Angeles, Los Angeles, CA
Margaret N. Shouse, Department of Neurobiology, Uni- H. Jürgen Wenzel, Department of Neurological Surgery,
versity of California Los Angeles, Los Angeles, CA University of California Davis, Davis, CA
Misty Smith-Yockman, Department of Pharmacology and H. Steve White, Department of Pharmacology & Toxicol-
Toxicology, Anticonvulsant Drug Development Program, ogy, Anticonvulsant Drug Development Program, Uni-
University of Utah, Salt Lake City, UT versity of Utah, Salt Lake City, UT
xiv Contributing Authors
Karen S. Wilcox, Department of Pharmacology & Toxi- Robert K.S. Wong, Department of Physiology and
cology, Anticonvulsant Drug Development Program, Pharmacology, SUNYHealth Science Center, Brooklyn,
University of Utah, Salt Lake City, UT NY
Philip A. Williams, Department of Biomedical Science, Qian Zhao, Department of Medicine, Dartmouth Medical
Colorado State University, Fort Collins, CO School, Dartmouth-Hitchcock Medical Center, Lebanon,
NH
L. James Willmore, Department of Neurology, Saint Louis
University School of Medicine, St. Louis, MO