Missouri Weekly Influenza Surveillance Report 2018-2019 Influenza Season

2019·14.7 MB·English

by  Missouri Department of Health and Senior Services

Missouri Weekly Influenza Surveillance Report
Missouri 2018-2019 Influenza Season1
DHSS

Oepor11ment ol Heolth
and s,mlor Se,,,Jc~$ Week 40: September 30 – October 6, 2018

All data are preliminary and may change as more reports are received.

Summary:
 The estimated influenza activity in Missouri is Sporadic2.

 During Week 40, a total of 64 laboratory-positive3 influenza cases (44 influenza A and 20 influenza B) were
reported. No laboratory-positive cases of influenza were reported by the Missouri State Public Health Laboratory
(MSPHL) during Week 40. The percentage of respiratory specimens testing positive for influenza in Missouri
laboratories reporting to the National Respiratory and Enteric Virus Surveillance System (NREVSS) remained
low during Week 40 (Figure 6).

 Influenza-like illness (ILI) activity was below baseline for both the Missouri Outpatient ILI Surveillance Network
(ILINet) and the hospital emergency room visit chief complaint data reported through ESSENCE. The reported
percentage of visits for ILI was 1.11% (Figure 5) and 1.22% (Figure 7) through ILINet and ESSENCE
respectively.4 The ILI data from a small number of sites located in the Northwest Region of the state is currently
unavailable in ESSENCE. Therefore, the ILI data for the Northwest Region should be interpreted with caution.

 No influenza-associated deaths have been reported in Missouri as of Week 40.5

 No influenza or ILI-associated outbreaks or school closures have been reported in Missouri as of Week 40.

 National influenza surveillance information is prepared by CDC and is included in the weekly FluView report,
which is available online at http://www.cdc.gov/flu/weekly/fluactivitysurv.htm.

1The 2018-2019 influenza season begins CDC Week 40 (week ending October 6, 2018) and ends CDC Week 39 (week ending September 28, 2019).

2Sporadic is defined as: Small numbers of laboratory-confirmed influenza cases or a single laboratory-confirmed influenza outbreak has been reported, but there is no
increase in cases of ILI.

3Laboratory-positive influenza includes the following test methods: rapid influenza diagnostic tests (antigen), reverse transcriptase polymerase chain reaction (RT-
PCR) and other molecular assays, immunofluorescence antibody staining (Direct (DFA) or Indirect (IFA)), or viral culture.

4Influenza-like illness (ILI) is defined by ILINet as fever (temperature of 100oF [37.8oC] or greater) and a cough and/or a sore throat without a known cause other than
influenza. ILI is defined by ESSENCE as Emergency Department chief complaints for Influenza or (FeverPlus and (Cough or SoreThroat) and not NonILIFevers).

5All influenza-associated deaths became reportable in Missouri in 2016.

Page 1 of 7
Surveillance Data:

Interactive Maps

The jurisdiction-specific influenza data are provided though interactive maps available at
http://bit.ly/MoFluMaps. Click on the jurisdiction to view the influenza data specific to that jurisdiction.
 Reported Laboratory-positive Influenza Cases by Influenza Type by Jurisdiction, CDC Week 40
 Reported Week-specific Rate per 100,000 Population, CDC Week 40
 Reported Laboratory-positive Influenza Cases by Influenza Type by Jurisdiction, Season-to-Date
 Reported Rate per 100,000 Population, Season-to-Date

Data Figures

Figure 1. Number of Laboratory-positive† Influenza Cases by Influenza Type,
Missouri, CDC Week 40 (September 30, 2018 - October 6, 2018)*

2018-2019*
Influenza Type Week 40
Season-to-Date
Influenza A
44 44
Influenza B
20 20
Influenza Unknown Or Untyped
0 0
Total
64 64
†
Laboratory-positive influenza includes the following test methods: rapid influenza diagnostic tests (antigen), reverse transcriptase polymerase chain
reaction (RT-PCR) and other molecular assays, immunofluorescence antibody staining (Direct (DFA) or Indirect (IFA)), or viral culture.
*Influenza season begins week ending October 6, 2018 (CDC Week 40) Data Source: Missouri Health Information Surveillance System (WebSurv).

Figure 2. Number of Laboratory-positive† Influenza Cases and Case Rates by Age Group,
Missouri, CDC Week 40 (September 30, 2018 - October 6, 2019)*‡

Week 40 Week 40 2018-2019* 2018-2019*
Age Group
Cases Rate‡ Season-to-Date Season-to-Date Rate‡
00-04 11 2.94 11 2.94
05-24 27 1.68 27 1.68
25-49 18 0.94 18 0.94
50-64 3 0.24 3 0.24
65+ 5 0.52 5 0.52
Total 64 1.05 64 1.05
†
Laboratory-positive influenza includes the following test methods: rapid influenza diagnostic tests (antigen), reverse transcriptase polymerase chain
reaction (RT-PCR) and other molecular assays, immunofluorescence antibody staining (Direct (DFA) or Indirect (IFA)), or viral culture.
*Influenza season begins week ending October 6, 2018 (CDC Week 40) Data Source: Missouri Health Information Surveillance System (WebSurv)
‡
Incidence Rate per 100,000 population

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Figure 3. Number of Laboratory-positive† Influenza Cases and Case Rates by Region,
Missouri, CDC Week 40 (September 30, 2018 - October 6, 2019)*‡

Week 40 Week 40 2018-2019* 2018-2019*
Region
Cases Rate‡ Season-to-Date Season-to-Date Rate‡
Central 20 2.95 20 2.95
Eastern 11 0.49 11 0.49
Northwest 2 0.13 2 0.13
Southeast 12 2.54 12 2.54
Southwest 19 1.77 19 1.77
Total 64 1.05 64 1.05
†
Laboratory-positive influenza includes the following test methods: rapid influenza diagnostic tests (antigen), reverse transcriptase polymerase chain
reaction (RT-PCR) and other molecular assays, immunofluorescence antibody staining (Direct (DFA) or Indirect (IFA)), or viral culture.
*Influenza season begins week ending October 6, 2018 (CDC Week 40) Data Source: Missouri Health Information Surveillance System (WebSurv)
‡
Incidence Rate per 100,000 population

Figure 4. Number of Laboratory-positive† Influenza Cases by CDC Week, Missouri, 2015-2019*

+
-8- 2-015-2016 2016-2011 -B-2017 -2018 ~ 2018~2-01s
I 1
16,000
14,000
12,000
10,000
C
0
u 8,000
n
t
6,000
4,000
2,000
4 4 4 4 4 4 4 4 4 4 5 5 5 0 0 0 0 0 0 0 0 0 1 1 1 1 1 1 1 1 1 1 2
0 1 2 3 4 5 6 7 8 9 0 1 2 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0
Week

†
Laboratory-positive influenza includes the following test methods: rapid influenza diagnostic tests (antigen), reverse transcriptase polymerase chain reaction (RT-

PCR) and other molecular assays, immunofluorescence antibody staining (Direct (DFA) or Indirect (IFA)), or viral culture.
*2018-2019 season-to-date through the week ending May 18, 2019 (Week 20).Data Source: Missouri Health Information Surveillance System (WebSurv).

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Figure 5. Percentage of Outpatient Visits for Influenza-like Illness (ILI), Missouri Outpatient ILI
Surveillance Network (ILINet) 2015-2019*†
12.00
• • • • • • Missouri Baseline•
11.00
- 2015-2016
10.00 - 2016-2017
9.00 - 2017-2018
- 2018-2019
8.00
;;;! 7.00
.E
...
"' 6.00
·.;;
>...
...C,,.: 5.00
...
Cl. 4.00
::,
0
0...,,. . 3.00
...
.C,: 2.00
u
ai
D. 1.00
0.00
40 41 42 43 44 45 46 47 48 49 so 51 52 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
CDC Week

*The ILINet Region 7 (MO, IA, KS, NE) baseline is the mean percentage of patient visits for ILI during non-influenza weeks for the previous three seasons,
plus two standard deviations. A non-influenza week is defined as periods of two or more consecutive weeks in which each week accounted for less than
2% of the season’s total number of specimens that tested positive for influenza. Data Source: U.S. Outpatient Influenza-like Illness Surveillance Network
(ILINet), Centers for Disease Control and Prevention (CDC).
†
2018-2019 season-to-date through the week ending May 18, 2019 (Week 20).

Figure 6. Season-to-Date PCR (+) Tests for Influenza in Missouri
350 40.00%
.~, 300 35.00%
E
·;:; 30.00%
1 250
V.',I
:->e 25.00%
;s 200
D.
20.00%
~
C:
~ 150
= 15.00%
~., 100
10.00%
.a
E
~ so
5.00%
40 42 44 46 48 so 52 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 36 38 40 42 44 46 48 so 52 2 4 6 8 10 12 14 16 18 20
2017-2018 CDC Week 2018-2019
- Influenza A {H1N1)pdm09 - Influenza A {H3N2) Influenza A Untyped - Influenza B --Percent Positivity

Data Source: National Respiratory and Enteric Virus Surveillance System (NREVSS), Centers for Disease Control and Prevention (CDC).
2018-2019 season-to-date through the week ending May 18, 2019 (Week 20).

Page 4 of 7
Figure 7. Percentage of Emergency Department (ED) Visits for Influenza-like Illness (ILI) in ESSENCE
Participating Hospitals, 2015-2019 Influenza Seasons*‡
9
- 2015-2016
8 - 2016-2017
7 - 2017-2018
- 2018-2019
l!l 6
~ ••••••• ESSENCE ILi Baseline*
::::i 5
2
0
40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
CDC week

*The ESSENCE ILI Baseline is the mean percent of ILI visits for each week during the previous three years (2015-17) when percentage of ILI
visits were less than 2% of total visits, plus two standard deviations. Data Source: Missouri Department of Health and Senior Services (DHSS),
Bureau of Reportable Disease Informatics, ESSENCE version 1.20.
‡
The ILI data from a small number of sites located in the Northwest Region of the state is temporarily unavailable in ESSENCE. Therefore, the
ILI data for the Northwest Region should be interpreted with caution.

Figure 8. Percentage of Emergency Department (ED) Visits for Influenza-like Illness (ILI) in ESSENCE
Participating Hospitals, by Age Group, Region and Statewide, Week 40, 2018*
30
28
26
24
22
"' 20
·i
> 18 ■ 0-4 Yrs
...
.Q. 16 ■ 5-24 Yrs
0
14
C ■ 25-49 Yrs
:O:I 12
OI ■ 50-64 Yrs
0. 10
■ 65 Yrs+
8
6
4
2
0
CENTRAL EASTERN NORTHWEST SOUTHEAST SOUTHWEST STATEWIDE

Data Source: Missouri Department of Health and Senior Services (DHSS), Bureau of Reportable Disease Informatics, ESSENCE version 1.20.
*The ILI data from a small number of sites located in the Northwest Region of the state is temporarily unavailable in ESSENCE. Therefore, the
ILI data for the Northwest Region should be interpreted with caution.
Page 5 of 7
Figure 9. Percentage of Emergency Department (ED) Visits for Influenza-like Illness (ILI) in ESSENCE
Participating Hospitals, by Region and Statewide, 2018-2019 Influenza Season*
14
13
12
11
10
- CENTRAL
-~"' 9
> 8 - EASTERN
::::;
.. 7 - NORTHWEST
0
C 6 - SOUTHEAST
QI
~ 5
QI - SOUTHWEST
Q,. 4
- -a-STATEWIDE
3 -
2 ...
1
I
0
40 41 42 43 44 45 46 47 48 49 50 51 52 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
CDC Week

Data Source: Missouri Department of Health and Senior Services (DHSS), Bureau of Reportable Disease Informatics, ESSENCE version 1.20.
*The ILI data from a small number of sites located in the Northwest Region of the state is temporarily unavailable in ESSENCE. Therefore, the
ILI data for the Northwest Region should be interpreted with caution.

Figure 10. Weekly Rate of Patients Hospitalized with Influenza and/or Pneumonia Syndromes in Missouri
Hospitals, 2015-2019 Influenza Seasons
22
20
18
C
·;,0.; 16
l
14
0
Q,. ~2015-2016
0 12
0
0, - 2016-2017
0 10
0
~... ~ 2017-2018
.aQ.I . 8
~ 2018-2019
,Q.I 6
ci::
4
2
0
404142434445464748495051~ 1 2 3 4 5 6 7 8 9 1011121314~1617IB~20
CDC Week

Data Source: Missouri Department of Health and Senior Services (DHSS), Bureau of Reportable Disease Informatics, HL7 Messaging Portal.
Population data from DHSS Population MICA 2016 (https://webapp01.dhss.mo.gov/MOPHIMS/QueryBuilder?qbc=PNM&q=1&m=1).

Page 6 of 7
Figure 11. Number of Patients Hospitalized with Influenza and/or Pneumonia Syndromes in Participating
Missouri Hospitals, by Age Group, Week 40, 2018-2019 Influenza Season
1400 ~---------------------------------------~ 20
18 - 0-4Yrs
1200 +----------------------------------------~
16 c: - 5-14Yrs
,Q"' 0
1000 -+-------------------------------------------< 14 -~
'lii :i - 15-64Yrs
,!:! 12 ~
-"~iii 800 D. - 65+Yrs
g
10
C.
(3 600 g0 ' --0-4Yrs
8
:I: Rate
0 .-I --5-14 Yrs
._ 400 6 ~
JQlI 4 CQ,I . --1R5a-te6 4 Yrs
E 200 ~
z::: , 2 c:: Rate
--65+Yrs
0 0 Rate
40414243444546474849505152 1 2 3 456789W111213M15~U18~20
CDC Week

Data Source: Missouri Department of Health and Senior Services (DHSS), Bureau of Reportable Disease Informatics, HL7 Messaging Portal.

Additional Influenza Data Sources:

Centers for Disease Control and Prevention: National Influenza Surveillance (FluView):
http://www.cdc.gov/flu/weekly/fluactivitysurv.htm

The National Respiratory and Enteric Virus Surveillance System (NREVSS):
https://www.cdc.gov/surveillance/nrevss/

World Health Organization: International Influenza Surveillance:
http://www.who.int/influenza/surveillance_monitoring/en/
Page 7 of 7
Missouri Weekly Influenza Surveillance Report
Missouri 1
2018-2019 Influenza Season
DHSS

Oepor11ment ol Heolth
and s,mlor S""'IC~$ Week 41: October 7 – October 13, 2018

All data are preliminary and may change as more reports are received.

Summary:
• The estimated influenza activity in Missouri is Sporadic2.

• During Week 41, a total of 147 laboratory-positive3 influenza cases (87 influenza A and 60 influenza B) were
reported. A season-to-date total of 288 laboratory-positive influenza cases (171 influenza A and 117 influenza B)
have been reported in Missouri as of Week 41. The influenza type for reported season-to-date cases includes 59%
influenza A and 41% influenza B. No laboratory-positive cases of influenza were reported by the Missouri State
Public Health Laboratory (MSPHL) during Week 41. The percentage of respiratory specimens testing positive for
influenza in Missouri laboratories reporting to the National Respiratory and Enteric Virus Surveillance System
(NREVSS) remained low during Week 41 (Figure 6).

• Influenza-like illness (ILI) activity was below baseline for both the Missouri Outpatient ILI Surveillance Network
(ILINet) and the hospital emergency room visit chief complaint data reported through ESSENCE. The reported
percentage of visits for ILI was 1.34% (Figure 5) and 1.29% (Figure 7) through ILINet and ESSENCE
respectively.4 The ILI data from a small number of sites located in the Northwest Region of the state is currently
unavailable in ESSENCE. Therefore, the ILI data for the Northwest Region should be interpreted with caution.

• No influenza-associated deaths have been reported in Missouri as of Week 41.5 During Week 40, 52 deaths
involving Pneumonia and Influenza (P&I) were reported to the Bureau of Vital Records.

• No influenza or ILI-associated outbreaks or school closures have been reported in Missouri as of Week 41.

• Seasonal influenza activity is low overall across the United States. National influenza surveillance information is
prepared by CDC and is included in the weekly FluView report, which is available online at
http://www.cdc.gov/flu/weekly/fluactivitysurv.htm.

1The 2018-2019 influenza season begins CDC Week 40 (week ending October 6, 2018) and ends CDC Week 39 (week ending September 28, 2019).

2Sporadic is defined as: Small numbers of laboratory-confirmed influenza cases or a single laboratory-confirmed influenza outbreak has been reported, but there is no
increase in cases of ILI.

3Laboratory-positive influenza includes the following test methods: rapid influenza diagnostic tests (antigen), reverse transcriptase polymerase chain reaction (RT-
PCR) and other molecular assays, immunofluorescence antibody staining (Direct (DFA) or Indirect (IFA)), or viral culture.

4Influenza-like illness (ILI) is defined by ILINet as fever (temperature of 100oF [37.8oC] or greater) and a cough and/or a sore throat without a known cause other than
influenza. ILI is defined by ESSENCE as Emergency Department chief complaints for Influenza or (FeverPlus and (Cough or SoreThroat) and not NonILIFevers).

5All influenza-associated deaths became reportable in Missouri in 2016.

Page 1 of 7
Surveillance Data:

Interactive Maps

The jurisdiction-specific influenza data are provided though interactive maps available at
http://bit.ly/MoFluMaps. Click on the jurisdiction to view the influenza data specific to that jurisdiction.
• Reported Laboratory-positive Influenza Cases by Influenza Type by Jurisdiction, CDC Week 41
• Reported Week-specific Rate per 100,000 Population, CDC Week 41
• Reported Laboratory-positive Influenza Cases by Influenza Type by Jurisdiction, Season-to-Date
• Reported Rate per 100,000 Population, Season-to-Date

Data Figures

Figure 1. Number of Laboratory-positive† Influenza Cases by Influenza Type,
Missouri, CDC Week 41 (October 7, 2018 - October 13, 2018)*

2018-2019*
Influenza Type Week 40 Week 41
Season-to-Date
Influenza A 84 87 171
Influenza B 57 60 117
Influenza Unknown Or Untyped 0 0 0
Total 141 147 288
†
Laboratory-positive influenza includes the following test methods: rapid influenza diagnostic tests (antigen), reverse transcriptase polymerase chain
reaction (RT-PCR) and other molecular assays, immunofluorescence antibody staining (Direct (DFA) or Indirect (IFA)), or viral culture.
*Influenza season begins week ending October 6, 2018 (CDC Week 40) Data Source: Missouri Health Information Surveillance System (WebSurv).

Figure 2. Number of Laboratory-positive† Influenza Cases and Case Rates by Age Group,
Missouri, CDC Week 41 (October 7, 2018 - October 13, 2018)*‡

Week 41 Week 41 2018-2019* 2018-2019*
Age Group
Cases Rate‡ Season-to-Date Season-to-Date Rate‡
00-04 29 7.75 51 13.62
05-24 68 4.24 112 6.98
25-49 27 1.41 75 3.92
50-64 11 0.89 23 1.86
65+ 12 1.26 27 2.83
Total 147 2.42 288 4.73
†
Laboratory-positive influenza includes the following test methods: rapid influenza diagnostic tests (antigen), reverse transcriptase polymerase chain
reaction (RT-PCR) and other molecular assays, immunofluorescence antibody staining (Direct (DFA) or Indirect (IFA)), or viral culture.
*Influenza season begins week ending October 6, 2018 (CDC Week 40) Data Source: Missouri Health Information Surveillance System (WebSurv)
‡
Incidence Rate per 100,000 population

Page 2 of 7
Figure 3. Number of Laboratory-positive† Influenza Cases and Case Rates by Region,
Missouri, CDC Week 41 (October 7, 2018 - October 13, 2018)*‡

Week 41 Week 41 2018-2019* 2018-2019*
Region
Cases Rate‡ Season-to-Date Season-to-Date Rate‡
Central 24 3.55 64 9.45
Eastern 8 0.35 31 1.37
Northwest 21 1.31 37 3.32
Southeast 82 17.38 122 25.86
Southwest 12 1.12 34 3.17
Total 147 2.42 288 4.73
†
Laboratory-positive influenza includes the following test methods: rapid influenza diagnostic tests (antigen), reverse transcriptase polymerase chain
reaction (RT-PCR) and other molecular assays, immunofluorescence antibody staining (Direct (DFA) or Indirect (IFA)), or viral culture.
*Influenza season begins week ending October 6, 2018 (CDC Week 40) Data Source: Missouri Health Information Surveillance System (WebSurv)
‡
Incidence Rate per 100,000 population

Figure 4. Number of Laboratory-positive† Influenza Cases by CDC Week, Missouri, 2015-2019*

*
1-e- + I
2015-2016 2016-2017 -B-2017-2018 2018-2019
16,000
14,000
12,000
H>,000
C
0
u 8,000
n
t
6,000
4,000
2,000
4 4 4 4 4 4 4 4 4 4 5 5 5 0 0 0 0 0 0 0 0 0 1 1 1 1 1 1 1 1 1 1 2
0 1 2 3 4 5 6 7 8 9 0 1 2 1 2 3 4 5 6 7 8 9 0 1 2 3 4 5 6 7 8 9 0
Week

†
Laboratory-positive influenza includes the following test methods: rapid influenza diagnostic tests (antigen), reverse transcriptase polymerase chain reaction (RT-

PCR) and other molecular assays, immunofluorescence antibody staining (Direct (DFA) or Indirect (IFA)), or viral culture.
*2018-2019 season-to-date through the week ending May 18, 2019 (Week 20).Data Source: Missouri Health Information Surveillance System (WebSurv).

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