Middleton's Allergy 2-Volume Set: Principles and Practice PDF
Preview Middleton's Allergy 2-Volume Set: Principles and Practice
How to go to your page This eBook contains two volumes. Each volume has its own page numbering scheme, consisting of a volume number and a page number, separated by a colon. For example, to go to page 5 of Volume 1, type 1:5 in the "page #" box at the top of the screen and click "Go." To go to page 5 of Volume 2, type 2:5… and so forth. Don’t Forget Your Online Access to Mobile. Searchable. Expandable. ACCESS it on any Internet-ready device SEARCH all Expert Consult titles you own LINK to PubMed abstracts ALREADY REGISTERED? FIRST-TIME USER? 1. Log in at expertconsult.com 1. REGISTER 2. Scratch off your Activation Code below • Click “Register Now” at expertconsult.com 3. Enter it into the “Add a Title” box • Fill in your user information and click “Continue” 4. Click “Activate Now” 2. ACTIVATE YOUR BOOK 5. Click the title under “My Titles” • Scratch off your Activation Code below • Enter it into the “Enter Activation Code” box • Click “Activate Now” • Click the title under “My Titles” For technical assistance: Activation Code email [email protected] call 800-401-9962 (inside the US) call +1-314-995-3200 (outside the US) Middleton’s ALLERGY PRINCIPLES AND PRACTICE This page intentionally left blank Middleton’s ALLERGY PRINCIPLES AND PRACTICE E I G H T H E D I T I O N — V O L U M E 1 N. Franklin Adkinson, Jr., MD Stephen T. Holgate, MD, Professor of Medicine DSc, FMedSci Division of Allergy and Clinical Immunology MRC Professor of Immunopharmacology Department of Medicine Clinical and Experimental Sciences Johns Hopkins University School of Medicine Faculty of Medicine Baltimore, Maryland, USA Southampton University and General Hospital Southampton, United Kingdom Bruce S. Bochner, MD Professor of Medicine and Director Robert F. Lemanske, Jr., MD Division of Allergy and Clinical Immunology Professor of Pediatrics and Medicine Department of Medicine Head, Division of Pediatric Allergy, Johns Hopkins University School of Medicine Immunology, and Rheumatology Baltimore, Maryland, USA University of Wisconsin School of Medicine and Public Health A. Wesley Burks, MD Madison, Wisconsin, USA Professor and Chair, Pediatrics Physician-in-Chief Robyn E. O’Hehir, FRACP, North Carolina Children’s Hospital PhD, FRCPath University of North Carolina at Chapel Hill Professor and Director Chapel Hill, North Carolina, USA Department of Allergy, Immunology, and Respiratory Medicine William W. Busse, MD Alfred Hospital and Monash University Professor of Medicine Melbourne, Victoria, Australia Department of Medicine Allergy, Pulmonary, and Critical Care Medicine University of Wisconsin School of Medicine and Public Health Madison, Wisconsin, USA 1600 John F. Kennedy Blvd. Ste. 1800 Philadelphia, PA 19103-2899 MIDDLETON’S ALLERGY PRINCIPLES AND PRACTICE Volume 1 PN 9996092240 Eighth Edition Volume 2 PN 9996092305 Two-volume set ISBN: 978-0-323-08593-9 Copyright © 2014 by Saunders, an imprint of Elsevier Inc. Copyright © 2009, 2003, 1998, 1993, 1988, 1983, 1978, by Mosby, an affiliate of Elsevier Inc. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier. com/permissions. This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein). Notices Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary. Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility. With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Library of Congress Cataloging-in-Publication Data Middleton’s allergy : principles and practice. —8th edition / N. Franklin Adkinson Jr. … [et al.]. p. ; cm. Allergy Includes bibliographical references and index. ISBN 978-0-323-08593-9 (two-volume set : alk. paper) I. Adkinson, N. Franklin, Jr. (Newton Franklin), 1943- II. Middleton, Elliott, Jr., 1925-1999. III. Title: Allergy. [DNLM: 1. Hypersensitivity. 2. Immunity. WD 300] RC584 616.97—dc23 2013014886 Cover image adapted from Figure 21.2 in Pathophysiology of Allergic Inflammation by Peter J. Barnes. Senior Content Strategist: Belinda Kuhn Deputy Content Development Manager: Joanne Scott Content Coordinator: Humayra Rahman Khan Publishing Services Manager: Anne Altepeter Project Manager: Louise King Design Manager: Louis Forgione Illustration Manager: Michael Carcel Illustrator: Oxford Illustrators, Chartwell; Dartmouth Publishing, Inc. Marketing Manager: Katie Alexo Printed in China Last digit is the print number: 9 8 7 6 5 4 3 2 1 CONTENTS Volume 1 16 Biology of Eosinophils 265 HIROHITO KITA | BRUCE S. BOCHNER SECTION A 17 Biology of Neutrophils 280 Basic Sciences Underlying Allergy and Immunology 1 KATHERINE J. BAINES | JODIE L. SIMPSON | PETER G. GIBSON 18 Biology of Monocytes and 1 Innate Immunity 2 Macrophages 292 ANDREW H. LIU | RICHARD B. JOHNSTON, JR. | MATTHEW J. FENTON KIAN FAN CHUNG | IAN M. ADCOCK 2 Adaptive Immunity 20 19 Airway Epithelial Cells 302 JAVIER CHINEN | THOMAS A. FLEISHER | WILLIAM T. SHEARER DARRYL KNIGHT | JEREMY HIROTA 3 Immunoglobulin Structure and Function 30 20 Noncontractile Functions of Airway Smooth Muscle 315 DIANE F. JELINEK | JAMES T. LI BRIAN G. OLIVER | JANETTE K. BURGESS | JUDITH BLACK | 4 Immune Tolerance 45 REYNOLD A. PANETTIERI, JR. MÜBECCEL AKDIS | CEZMI A. AKDIS 21 Pathophysiology of Allergic Inflammation 327 5 Cytokines in Allergic Inflammation 65 PETER J. BARNES JOHN W. STEINKE | LANNY J. ROSENWASSER | LARRY BORISH 22 Genetics and Epigenetics in Allergic Diseases 6 Cellular Adhesion in Inflammation 83 and Asthma 343 DAVID H. BROIDE | P. SRIRAMARAO JOHN W. HOLLOWAY 7 Chemokines 98 23 Immunobiology of IgE and IgE ZAMANEH MIKHAK | ANDREW D. LUSTER Receptors 364 8 The Complement System 113 HANS C. OETTGEN KATHLEEN E. SULLIVAN | ANETE S. GRUMACH 24 Neuronal Control of Airway Function in 9 Lipid Mediators of Hypersensitivity and Allergy 378 Inflammation 139 BRADLEY J. UNDEM | BRENDAN J. CANNING R. STOKES PEEBLES, JR. | JOSHUA A. BOYCE 25 Resolution of Allergic Inflammation 389 10 Molecular Biology and Genetic DAVID A. DORWARD | CHRISTOPHER D. LUCAS | KEITH C. ALLEN | ADRIANO G. ROSSI Engineering 162 SUDHIR GUPTA | LEMAN YEL SECTION B Aerobiology and Allergens 397 11 Signal Transduction 184 PAUL J. BERTICS | CYNTHIA J. KOZIOL-WHITE | 26 The Structure and Function of Allergens 398 MONICA L. GAVALA | GREGORY J. WIEPZ GEOFFREY A. STEWART | JONATHAN P. RICHARDSON | 12 Biology of Lymphocytes 203 JIHUI ZHANG | CLIVE ROBINSON LAUREN COHN | CATHERINE HAWRYLOWICZ | ANURADHA RAY 27 Aerobiology of Outdoor Allergens 430 13 Antigen-Presenting Dendritic Cells 215 RICHARD W. WEBER BART N. LAMBRECHT | HAMIDA HAMMAD 28 Indoor Allergens 453 14 Biology of Mast Cells and Their Mediators 228 THOMAS A.E. PLATTS-MILLS PETER BRADDING | HIROHISA SAITO 29 Preparation and Standardization of Allergen Extracts 470 15 Biology of Basophils 252 JAY E. SLATER | ROBERT E. ESCH JOHN T. SCHROEDER v vi Contents 30 Air Pollution: Indoor and Outdoor 482 45 Respiratory Tract Mucosal Immunology 715 MICHELLE L. HERNANDEZ | DAVID B. PEDEN HOLGER GARN | HARALD RENZ 31 Particulate and Pollen Interactions 497 46 Airway Smooth Muscle Function in JOHANNES RING | JEROEN BUTERS | HEIDRUN BEHRENDT Asthma: Extracellular Matrix and Airway Remodeling 730 32 Effect of the Food Matrix and Processing on ANDREW J. HALAYKO | THAI TRAN the Allergenic Activity of Foods 508 E.N. CLARE MILLS 47 Airway Mucus and the Mucociliary System 739 SECTION C DUNCAN F. ROGERS The Skin 517 48 Epidemiology of Asthma and Allergic 33 Structure of the Skin and Cutaneous Airway Diseases 754 Immunology 518 GRAHAM DEVEREUX | ELIZABETH C. MATSUI | PETER G.J. BURNEY DOUGLAS A. PLAGER | THOMAS BIEBER | MARK R. PITTELKOW 49 Ontogeny of Immune Development and 34 Atopic Dermatitis 540 Its Relationship to Allergic Diseases MARK BOGUNIEWICZ | DONALD Y.M. LEUNG and Asthma 790 35 Contact Dermatitis 565 SUSAN L. PRESCOTT | CHRISTINE SEROOGY ROSEMARY L. NIXON | THOMAS DIEPGEN 50 Asthma Pathogenesis 812 36 Urticaria and Angioedema 575 STEPHEN T. HOLGATE | PETER D. SLY SARBJIT S. SAINI 51 Mouse Models of Allergic Airways Disease 842 37 Hereditary Angioedema and Bradykinin- CLARE LLOYD | IAN P. LEWKOWICH | MARSHA WILLS-KARP | Mediated Angioedema 588 SEJAL SAGLANI BRUCE L. ZURAW | SANDRA C. CHRISTIANSEN 52 Diagnosis of Asthma in Infants and 38 Immune Complex–Mediated Diseases 602 Children 861 MICHAEL M. FRANK | C. GARREN HESTER THERESA W. GUILBERT | ROBERT F. LEMANSKE, JR. | DANIEL J. JACKSON SECTION D The Eye 617 53 Management of Asthma in Infants and Children 876 39 Allergic and Immunologic Diseases of DANIEL J. JACKSON | ROBERT F. LEMANSKE, JR. | THERESA W. GUILBERT the Eye 618 NEAL P. BARNEY | ELLEN B. COOK | JAMES L. STAHL 54 Diagnosis of Asthma in Adults 892 LOUIS-PHILIPPE BOULET SECTION E Respiratory Tract 639 55 Management of Asthma in Adolescents and Adults 902 40 The Nose and Control of Nasal Airflow 640 SANDY R. DURRANI | WILLIAM W. BUSSE RONALD ECCLES 56 Emergency Treatment and Approach to the 41 Nasal Provocation Testing 652 Patient with Acute Asthma 923 GUY W. SCADDING | TREVOR T. HANSEL | STEPHEN R. DURHAM CARLOS A. CAMARGO, JR. | BRIAN H. ROWE 42 Allergic and Nonallergic Rhinitis 664 57 Approach to the Patient with Exercise- JONATHAN CORREN | FUAD M. BAROODY | RUBY PAWANKAR Induced Bronchoconstriction 938 TEAL S. HALLSTRAND 43 Rhinosinusitis and Nasal Polyps 686 CLAUS BACHERT | LIEN CALUS | PHILIPPE GEVAERT 58 Asthma and Allergic Diseases during Pregnancy 951 44 Development, Structure, and Physiology in MICHAEL SCHATZ | ROBERT S. ZEIGER | REUBEN FALKOFF | Normal Lung and in Asthma 700 CHRISTINA CHAMBERS | ERIC MACY | MICHAEL H. MELLON CHARLES G. IRVIN Contents vii 59 Occupational Allergy and Asthma 970 73 Human Immunodeficiency Virus and Allergic CATHERINE LEMIÈRE | OLIVIER VANDENPLAS Disease 1175 SARAH K. NICHOLAS | MARY E. PAUL | WILLIAM T. SHEARER 60 Pathology of Asthma 986 RAKESH K. KUMAR | PETER K. JEFFERY 74 Laboratory Tests for Allergic and Immunodeficiency Diseases 1187 61 Allergic Bronchopulmonary Aspergillosis and ROBERT G. HAMILTON Hypersensitivity Pneumonitis 1000 JO A. DOUGLASS | ALESSANDRA SANDRINI | 75 Eosinophilia and Eosinophil-Related STEPHEN T. HOLGATE | ROBYN E. O’HEHIR Disorders 1205 AMY D. KLION | PETER F. WELLER 62 Immunologic Nonasthmatic Diseases of the Lung 1014 76 Mastocytosis 1224 MICHAEL C. SNELLER | JOSEPH R. FONTANA | DEAN D. METCALFE JAMES H. SHELHAMER 63 Approach to the Patient with Chronic 77 Anaphylaxis 1237 Cough 1032 SIMON G.A. BROWN | STEPHEN F. KEMP | PHILLIP L. LIEBERMAN J. MARK MADISON | RICHARD S. IRWIN 78 Insect Allergy 1260 64 Bronchial Challenge Testing 1042 DAVID B.K. GOLDEN DONALD W. COCKCROFT 79 Drug Allergy 1274 65 Lung Imaging 1056 GÜLFEM E. ÇELIK | WERNER J. PICHLER | N. FRANKLIN ADKINSON, JR. MARIO CASTRO | SEAN B. FAIN | CHRISTOPHER E. BRIGHTLING 80 Hypersensitivity to Aspirin and Other 66 Aerosols and Aerosol Drug Delivery Nonsteroidal Antiinflammatory Drugs 1296 Systems 1066 HAE-SIM PARK | MAREK L. KOWALSKI | MARIO SANCHEZ-BORGES BETH L. LAUBE | MYRNA B. DOLOVICH 81 Reactions to Foods 1310 Volume 2 ANNA NOWAK-WE˛GRZYN | A. WESLEY BURKS | HUGH A. SAMPSON SECTION F 82 Reactions to Food and Drug Gastrointestinal Tract 1083 Additives 1340 ROBERT K. BUSH | STEVE L. TAYLOR 67 Gastrointestinal Mucosal Immunology 1084 M. CECILIA BERIN | GLENN T. FURUTA | SEEMA S. ACEVES 83 Oral Food Challenge Testing 1357 ROBERT A. WOOD 68 Eosinophilic Gastrointestinal Disorders 1095 MARC E. ROTHENBERG 84 Food Allergy Management 1365 SCOTT H. SICHERER | GIDEON LACK | STACIE M. JONES SECTION G Systemic Disease 1107 85 Adverse Reactions to Vaccines for Infectious Diseases 1384 69 Clinical Significance of JOHN M. KELSO | MATTHEW J. GREENHAWT Immunoglobulin E 1108 SECTION H PHILIP H. SMITH | DENNIS R. OWNBY Therapeutics 1405 70 In Vivo Methods for the Study and Diagnosis of Allergy 1119 86 Allergen Control for Prevention and ANCA MIRELA CHIRIAC | JEAN BOUSQUET | PASCAL DEMOLY Management of Allergic Diseases 1406 ADNAN CUSTOVIC | EUAN TOVEY 71 Approach to the Patient with Recurrent Infections 1133 87 Injection Immunotherapy for Inhalant MARK BALLOW | HEATHER K. LEHMAN Allergens 1416 HAROLD S. NELSON 72 Primary Immunodeficiency Diseases 1144 REBECCA H. BUCKLEY | JORDAN S. ORANGE
Description:The list of books you might like
