Microbial Biofilms in Healthcare: Formation, Prevention and Treatment

168 Pages·2020·12.702 MB·English

by  TBD, Karen Vickery (editor)

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Microbial Biofilms
in Healthcare
Formation, Prevention and
Treatment
Edited by
Karen Vickery
Printed Edition of the Special Issue Published in Materials
www.mdpi.com/journal/materials
Microbial Biofilms in Healthcare

Microbial Biofilms in Healthcare
Formation, Prevention and Treatment
SpecialIssueEditor
KarenVickery
MDPI•Basel•Beijing•Wuhan•Barcelona•Belgrade•Manchester•Tokyo•Cluj•Tianjin
SpecialIssueEditor
KarenVickery
MacquarieUniversity
Australia
EditorialOffice
MDPI
St.Alban-Anlage66
4052Basel,Switzerland
This is a reprint of articles from the Special Issue published online in the open access journal
Materials(ISSN1996-1944)(availableat:https://www.mdpi.com/journal/materials/specialissues/
microbialbiofilmhealthcare).
Forcitationpurposes,citeeacharticleindependentlyasindicatedonthearticlepageonlineandas
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LastName,A.A.; LastName,B.B.; LastName,C.C.ArticleTitle. JournalNameYear,ArticleNumber,
PageRange.
ISBN978-3-03928-410-8(Pbk)
ISBN978-3-03928-411-5(PDF)
(cid:2)c 2020bytheauthors. ArticlesinthisbookareOpenAccessanddistributedundertheCreative
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licenseCCBY-NC-ND.
Contents
AbouttheSpecialIssueEditor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii
Prefaceto”MicrobialBiofilmsinHealthcare:Formation,PreventionandTreatment” . . . . . ix
KarenVickery
SpecialIssue:MicrobialBiofilmsinHealthcare:Formation,PreventionandTreatment
Reprintedfrom:Materials2019,12,2001,doi:10.3390/ma12122001 . . . . . . . . . . . . . . . . . . 1
ShamailaTahir,MatthewMalone,HonghuaHu,AnandDevaandKarenVickery
The Effect of Negative Pressure Wound Therapy with and without Instillation on Mature
BiofilmsInVitro
Reprintedfrom:Materials2018,11,811,doi:10.3390/ma11050811. . . . . . . . . . . . . . . . . . . 5
LasserreJe´roˆmeFre´de´ric,BrecxMichelandTomaSelena
OralMicrobes,BiofilmsandTheirRoleinPeriodontalandPeri-ImplantDiseases
Reprintedfrom:Materials2018,11,1802,doi:10.3390/ma11101802 . . . . . . . . . . . . . . . . . . 17
MariaMempin,HonghuaHu,DurdanaChowdhury,AnandDevaandKarenVickery
TheA,BandC’sofSiliconeBreastImplants: AnaplasticLargeCellLymphoma,Biofilmand
CapsularContracture
Reprintedfrom:Materials2018,11,2393,doi:10.3390/ma11122393 . . . . . . . . . . . . . . . . . . 35
MarieBeitelshees,AndrewHill,CharlesH.JonesandBlaineA.Pfeifer
Phenotypic Variation during Biofilm Formation: Implications for Anti-Biofilm
Therapeutic Design
Reprintedfrom:Materials2018,11,1086,doi:10.3390/ma11071086 . . . . . . . . . . . . . . . . . . 47
KatarzynaLedwochandJean-YvesMaillard
CandidaaurisDrySurfaceBiofilm(DSB)forDisinfectantEfficacyTesting
Reprintedfrom:Materials2019,12,18,doi:10.3390/ma12010018 . . . . . . . . . . . . . . . . . . . 65
NorFadhilahKamaruzzaman,TanLiPeng,KhairunAnisaMatYazid,ShamsaldeenIbrahim
Saeed,RuhilHayatiHamdan,ChoongSiewShean,WongWengKin,AlexandruChivuand
AmandaJaneGibson
TargetingtheBacterialProtectiveArmour;ChallengesandNovelStrategiesintheTreatmentof
MicrobialBiofilm
Reprintedfrom:Materials2018,11,1705,doi:10.3390/ma11091705 . . . . . . . . . . . . . . . . . . 75
Phillip A. Laycock, John J. Cooper, Robert P. Howlin, Craig Delury, Sean Aiken and
Paul Stoodley
In Vitro Efficacy of Antibiotics Released from Calcium Sulfate Bone Void Filler Beads
Reprintedfrom:Materials2018,11,2265,doi:10.3390/ma11112265 . . . . . . . . . . . . . . . . . . 103
MuhammadYasir,MarkDuncanPerryWillcoxandDebarunDutta
ActionofAntimicrobialPeptidesagainstBacterialBiofilms
Reprintedfrom:Materials2018,11,2468,doi:10.3390/ma11122468 . . . . . . . . . . . . . . . . . . 119
BinduSubhadra,DongHoKim,KyunghoWoo,SuryaSurendranandChulHeeChoi
Control of Biofilm Formation in Healthcare: Recent Advances Exploiting Quorum-Sensing
InterferenceStrategiesandMultidrugEffluxPumpInhibitors
Reprintedfrom:Materials2018,11,1676,doi:10.3390/ma11091676 . . . . . . . . . . . . . . . . . . 135
v

About the Special Issue Editor
KarenVickerygraduatedfromVeterinarySciencewithhonorsin1979andworkedingeneral
veterinarypracticeinAustraliaandtheUnitedKingdom.SheobtainedherPh.D.in1996investigating
hepatitis B virus (HBV) and developed the method for biocide efficacy testing against HBV for
disinfectant registration referenced by the Australian Therapeutic Goods Administration. She is
theScientificDirectoroftheSurgicalInfectionResearchGroupatMacquarieUniversity, Australia
andisprimarilyresponsibleforinvestigatingmedicallyimportantbiofilms. Herresearchaimsto
preventhealthcareassociatedinfectionsbyfocusingonbothsurgicalstrategiesforpreventingbiofilm
infection of medical implants, treating biofilm infections of chronic wounds, and strategies that
improveinstrumentandenvironmentaldecontamination.
vii

Preface to ”Microbial Biofilms in Healthcare:
Formation, Prevention and Treatment”
An estimated 99% of the world’s bacteria live in close proximity with other bacteria in a biofilm.
In a biofilm, the bacteria are enclosed in exopolymeric substances (EPS) and are generally attached
to a surface. The biofilm phenotype and the surrounding EPS increase the tolerance of bacteria to
desiccation and biocide action, resulting in bacterial persistence on surfaces long after free-swimming
or planktonic bacteria are killed. In this book, we investigate the role of biofilms in breast and dental
implant disease and cancer. We include in vitro models for investigating treatment of chronic wounds
and disinfectant action against Candida sp. Also included are papers on the most recent strategies for
treating biofilm infection ranging from antibiotics incorporated into bone void fillers to antimicrobial
peptides and quorum sensing.
KarenVickery
SpecialIssueEditor
ix