Mechanics of Biological Systems and Materials, Volume 6: Proceedings of the 2015 Annual Conference on Experimental and Applied Mechanics PDF
Preview Mechanics of Biological Systems and Materials, Volume 6: Proceedings of the 2015 Annual Conference on Experimental and Applied Mechanics
Conference Proceedings of the Society for Experimental Mechanics Series Srinivasan Arjun Tekalur Pablo Zavattieri Chad S Korach Editors Mechanics of Biological Systems and Materials, Volume 6 Proceedings of the 2015 Annual Conference on Experimental and Applied Mechanics Conference Proceedings of the Society for Experimental Mechanics Series Series Editor Kristin B. Zimmerman, Ph.D Society for Experimental Mechanics Bethel, CT, USA More information about this series at h ttp://www.springer.com/series/8922 Srinivasan Arjun Tekalur (cid:129) Pablo Zavattieri (cid:129) Chad S. Korach Editors Mechanics of Biological Systems and Materials, Volume 6 Proceedings of the 2015 Annual Conference on Experimental and Applied Mechanics Editors Srinivasan Arjun Tekalur Pablo Zavattieri Michigan State University Purdue University East Lansing , MI , USA West Lafayette , USA Chad S. Korach Department of Mechanical Engineering State University of New York at Stony Brook Stony Brook , NY , USA ISSN 2191-5644 ISSN 2191-5652 (electronic) Conference Proceedings of the Society for Experimental Mechanics Series ISBN 978-3-319-21454-2 ISBN 978-3-319-21455-9 (eBook) DOI 10.1007/978-3-319-21455-9 Library of Congress Control Number: 2015945112 Springer Cham Heidelberg New York Dordrecht London © The Society for Experimental Mechanics, Inc. 2016 T his work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifi cally the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfi lms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com) Pref ace Mechanics of Biological Systems and Materials represents one of nine volumes of technical papers presented at the SEM 2015 SEM Annual Conference and Exposition on Experimental and Applied Mechanics organized by the Society for Experimental Mechanics and held in Costa Mesa, CA, June 8–11, 2015. The complete Proceedings also include volumes on Dynamic Behavior of Materials; Challenges In Mechanics of Time-Dependent Materials; Advancement of Optical Methods in Experimental Mechanics; Experimental and Applied Mechanics; MEMS and Nanotechnology; Mechanics of Composite and Multifunctional Materials; Fracture, Fatigue, Failure and Damage Evolution; and Residual Stress, Thermomechanics and Infrared Imaging, Hybrid Techniques and Inverse Problems. Each collection presents early fi nd- ings from experimental and computational investigations on an important area within Experimental Mechanics, the Mechanics of Biological Systems and Materials being one of these areas. This volume summarizes the exchange of ideas and information among scientists and engineers involved in the research and analysis of how mechanical loads interact with the structure, properties, and function of living organisms and their tissues. The scope includes experimental, imag- ing, numerical, and mathematical techniques and tools spanning various length and time scales. Establishing this sympo- sium at the Annual Meeting of the Society for Experimental Mechanics provides a venue where state-of-the-art experimental methods can be leveraged in the study of biomechanics. A major goal of the symposium was for participants to collaborate in the asking of fundamental questions and the development of new techniques to address bio-inspired problems in society, human health, and the natural world. The organizers would like to thank all the speakers and staff at SEM for enabling a successful program. East Lansing, MI, USA Srinivasan Arjun Tekalur West Lafayette, IN, USA Pablo Zavattieri Stony Brook, NY, USA Chad S. Korach v Contents 1 Damage in Brain Tissue Due to Single Bubble Cavitation Shock ...................................................................... 1 Ghatu Subhash , Saranya Canchi , Yu Hong , Malisa Sarntinoranont , and Michael A. King 2 Inflation Test of the Human Optic Nerve Head Using Digital Volume Correlation ......................................... 7 Dan E. Midgett , Harry A. Quigley , Mary E. Pease , Christian Franck , Jennet Toyjanova , and Thao D. Nguyen 3 In Situ NANO-Indentation of Round Window Membrane ................................................................................. 17 Hirobumi Watanabe , Anil K. Lalwani , and Jeffrey W. Kysar 4 Transient Response of the Eardrum Excited by Localized Mechanical Forces ................................................ 31 P. Razavi , I. Dobrev , M. Ravicz , J. T. Cheng , C. Furlong , and J. J. Rosowski 5 In Vitro Quantification of Optimal Impact Properties for Microneedle Penetration ...................................... 39 K. Moronkeji , S. Todd , I. Dawidowska , and R. Akhtar 6 DIC Measurements of the Human Heart During Cardiopulmonary Bypass Surgery ..................................... 51 Mikko Hokka , Nikolas Mirow , Horst Nagel , Sebastian Vogt , and Veli-Tapani Kuokkala 7 Comparing 2D and 3D Digital Image Correlation for an Inflation Test............................................................ 61 Barbara J. Murienne and Thao D. Nguyen 8 Determination of Cardiac Wall Deformations from MRI Images ...................................................................... 69 C.A. Sciammarella , L. Lamberti , and A. Boccaccio 9 A Deeper Look Into Immature Porcine Zona Pellucida Visco-hyperelasticity ................................................. 85 A. Boccaccio , L. Lamberti , M. Papi , M. De Spirito , and C. Pappalettere 10 Induced Coupling Between Contractile Cells ....................................................................................................... 91 Brian J. Williams and M. Taher A. Saif 11 In-Vivo Indentation Testing of Sheep Spinal Cord with Meninges .................................................................... 99 Haitao Zhang , Phillip Falkner , and Chad Cai 12 Polydimethylsiloxane Lanes Enhance Sarcomere Organization in Human ESC- Derived Cardiomyocytes ............................................................................................................. 105 Brett N. Napiwocki , Max R. Salick , Randolph S. Ashton , and Wendy C. Crone 13 Electrospin Fiber Affect on the Strength of Metal–Cement Interfaces ............................................................. 113 S. Riahinezhad , Y. Li , and M. Khandaker vii viii Contents 14 A Nanomechanics Based Investigation into Interface Thermomechanics of Collagen and Chitin Based Biomaterials .............................................................................................................................. 119 Tao Qu , Devendra Verma , and Vikas Tomar 15 The Growth and Mechanical Properties of Abalone Nacre Mesolayer ............................................................. 127 Yan Chen , MariAnne Sullivan , and Barton C. Prorok 16 Novel Bending Fatigue Testing of Small Medical Device Cables ........................................................................ 133 Haitao Zhang and Bernard Li 17 Complex Shear Modulus of Hydrogels Using a Dynamic Nanoindentation Method ....................................... 141 R. Akhtar , E.R. Draper , D.J. Adams , and H. Pfaff 18 Characterization of Acoustically- Induced Forces of the Human Eardrum ...................................................... 147 Morteza Khaleghi , Cosme Furlong , Jeffrey Tao Cheng , and John J. Rosowski Chapter 1 Damage in Brain Tissue Due to Single Bubble Cavitation Shock Ghatu Subhash, Saranya Canchi, Yu Hong, Malisa Sarntinoranont, and Michael A. King Abstract A novel experimental technique was developed to visualize and control single bubble cavitation initiation, growth, and its collapse. The influence of this process on a nearby tissue surrogate was investigated and then extended to a rat brain tissue.ThetechniqueutilizedamodifiedpolymerHopkinsonpressurebarsystemwhichtransmitsasimulatedblastpressure wave with over and under pressure components to a fluid-filled test chamber implanted with a seed gas bubble. Growth and collapse of this bubble was visually recorded with a high speed camera. Using Raleigh-Plessat equation, bubble collapse pressures 29–125 times that of peak blast overpressure are predicted to be the source of localized shock waves. Finally, the value of this experimental platform to investigate the single bubble cavitation- induced fluid jet impact on a rat brain tissue and the associated damage evolution is illustrated. Keywords Cavitation•Traumaticbraininjury•Agarosehydrogel•Shockwave•Braintissue 1.1 Introduction Blast-inducedtraumaticbraininjury(bTBI),a‘signatureinjury’ofmoderndaywarfare,hasaffectedseveralthousandsof soldiers returning from the recent wars [1]. Symptoms of these patients often range from mood swings to memory loss. Numerous possible mechanisms have been proposed including injury due to rapid accelerating—decelerating forces in the brain, multiple wave reflections with in the brain, impedance mismatch between heterogeneous tissue types, and cavitation [2].Hereweconcernourselveswithcavitationcausedbyblastwavesconsistingoflargeoverpressure(compressive)and smaller underpressure (tensile) components. The blast wave impinges on the head, leading to a portion of the wave being transmitted into cerebrospinal fluid (CSF) and brain tissue, both of which carry dissolved gasses. Within the short time period of blast wave transmission, there is potential for cavitation bubbles to form (during under-pressure phase), grow, and collapse within fluid spaces inside the head. When these bubbles collapse, considerable energy is released either in the form of local shock waves or generation of a high-speed fluid jet which may cause additional damage as it impinges on tissue. Such cavitation damage of material surfaces is well established since the original work of Rayleigh who first studied pitting of ship propeller blades or water turbine blades [3, 4]whichiscommonlyreferredtoas‘cavitationerosion’.Thus,collaps- ing cavitation bubbles in the brain may cause local damage to nearby tissues or blood vessels. A fundamental problem in the study of cavitation is that a testing platform is not readily available to control bubble growth and collapse. In this study, a novel experimental system capable of investigating single bubble cavitation was devel- oped. The system was first utilized to quantify the dynamic behavior of a tissue surrogate from single bubble collapse. In the second phase the system is used to investigate damage in a biological tissue. G. Subhash (*)•S.Canchi•Y.Hong•M.Sarntinoranont Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, FL 32611, USA e-mail: [email protected] M.A. King Department of Pharmacology and Therapeutics, University of Florida, Gainesville, FL 32611, USA © The Society for Experimental Mechanics, Inc. 2016 1 S.A. Tekalur et al. (eds.), Mechanics of Biological Systems and Materials, Volume 6, Conference Proceedings of the Society for Experimental Mechanics Series, DOI 10.1007/978-3-319-21455-9_1
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