MBE Emerging Classics 2022 Heather Rowe* InstituteforGenomicsandEvolutionaryMedicine,TempleUniversity,Philadelphia,PA,USA *Correspondingauthor:E-mail:[email protected]. Since 2013, Molecular Biology and Evolution has celebrated ExtremegenomicCpGdeficiencyinSARS-CoV-2andevasion paperswithpowerfulimpactonourcommunityasreflected ofhostantiviraldefense(2020)XiainVolume37(9)Pp.2699– byaccumulatedcitations.Below,wehighlighttendiscoveries, 2705. five methods, and five resource publications as “Emerging EvolutionofRosaceaefruittypesbasedonnuclearphylogeny Classics”basedoncitationsaccruedperfractionalyearssince in the context of geological times and genome duplication publication.Articleswithincategoriesarelistedinalphabet- (2017)XiangandcolleaguesinVolume34(2)Pp.262–281. icalorderbasedonthefamilynameofthefirstauthor.Total Methods D citation counts were obtained from Web of Science on o w November 30, 2021. We congratulate these authors on the Genomic infectious disease epidemiology in partially sampled nlo significanceoftheircontributionsandlookforwardtopub- and ongoing outbreaks (2017) Didelot and colleagues in ad e lishingmanyhigh-impactarticlesintheyearstocome. VoTluhmeeu3n4r(e4a)sPonpa.b99le7–e1ff0e0c7ti.veness of convolutional neural d fro m Discoveries networks in population genetic inference (2019) Flagel and h Largevariationintheratioofmitochondrialtonuclearmuta- colAleafgaustelsikineliVhoooludmmee3th6o(2d)toPpr.ec2o2n0s–tr2u3c8t.andvisualizeances- ttps://a tionrateacrossanimals:implicationsforgeneticdiversityand c tralscenarios(2019)IshikawaandcolleaguesinVolume36(9) ad theuseofmitochondrialDNAas amolecularmarker(2017) e Pp.2069–2085. m AllioandcolleaguesinVolume34(11)Pp.2762–2772. ic Newmethodstocalculateconcordancefactorsforphyloge- .o EvolutionofDNAmethylationacrossinsects(2017)Bewick u nomicdatasets(2020)MinhandcolleaguesinVolume37(9) p andcolleaguesinVolume34(3)Pp.654–665. Pp.2727–2733. .com Thericeparadox:multipleoriginsbutsingledomestication TheoreticalfoundationoftheRelTimemethodforestimat- /m in Asian rice (2017) Choi and colleagues in Volume 34(4) ing divergence times from variable evolutionary rates (2018) be/a Pp.969–979. TamuraandcolleaguesinVolume35(7)Pp.1770–1782. rtic DecipheringtheroutesofinvasionofDrosophilasuzukiiby le /3 meansofABCrandomforest(2017)Fraimoutandcolleagues Resources 9 /1 inVolume34(4)Pp.980–996. /m UFBoot2: improving the ultrafast bootstrap approximation s Betweenapodandahardtest:thedeepevolutionofamoe- a (2018)HoangandcolleaguesinVolume35(2)Pp.518–522. Eb3 bae (2017) Kang and colleagues in Volume34(9) Pp. 2258– MEGA X: molecular evolutionary genetics analysis across d57 2270. computing platforms (2018) Kumar and colleagues in it/651 Genomic analysis of European Drosophila melanogaster Volume35(6)Pp.1547–1549. o63 pleocptiuonla,tiaonnds rperveevaiolsuslolynguintukdnionwalnsDtrNucAtuvreir,ucsoesnt(in20en20t-)wKidaepusen- moPdaerlstitoiofnevFoinludteiron2f:ornemwolemcuetlahrodasndfomrosreplehcotilnoggicpaalrpthityiolongeed- rial12 by g andcolleaguesinVolume37(9)Pp.2661–2678. neticanalyses(2017)LanfearandcolleaguesinVolume34(3) ue s AdaptationofS.cerevisiaetofermentedfoodenvironments Pp.772–773. t o n revealsremarkablegenomeplasticityandthefootprintsofdo- IQ-TREE 2: new models and efficient methods for phyloge- 3 1 mestication (2018) Legras and colleagues in Volume 35(7) neticinferenceinthegenomicera(2020)Minhandcolleagues J a Pp.1712–1727. inVolume37(5)Pp.1530–1534. nu a Genomic evidence for complex domestication history of DnaSP 6: DNA sequence polymorphism analysis of large ry 2 the cultivated tomato in Latin America (2020) Razifard and data sets (2017) Rozas and colleagues in Volume 34(12) 0 2 2 colleaguesinVolume37(4)Pp.1118–1132. Pp.3299–3302. (cid:2)TheAuthor(s)2021.PublishedbyOxfordUniversityPressonbehalfoftheSocietyforMolecularBiologyandEvolution. ThisisanOpenAccessarticledistributedunderthetermsoftheCreativeCommonsAttributionLicense(https://creativecommons. org/licenses/by/4.0/),whichpermitsunrestrictedreuse,distribution,andreproductioninanymedium,providedtheoriginalworkis Open Access properlycited. Mol.Biol.Evol.39(1):msab357 doi:10.1093/molbev/msab357 1