Mass Spectrometry in Drug Metabolism and Pharmacokinetics PDF
393 Pages·2009·13.931 MB·English
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Evolving role of mass spectrometry in drug discovery and development / Dil M. Ramanathan and Richard M. LeLacheur -- Quantitative bioanalysis in drug discovery and development: principles and applications / Ayman El-Kattan, Chris Holliman, and Lucinda H. Cohen -- Quadrupole, triple-quadrupole, and hybrid linear ion trap mass spectrometers in metabolite analysis / Elliott B. Jones -- Applications of quadrupole time-of-flight mass spectrometry in reactive metabolite screening / Jose M. Castro-Perez -- Changing role of FTMS in drug metabolism / Petia A. Shipkova, Jonathan L. Josephs, and Mark Sanders -- High-resolution LC-MS based mass defect filter approach: basic concept and application in metabolite detection / Haiying Zhang ... [et al.]., Applications of high-sensitivity mass spectrometry and radioactivity detection techniques in drug metabolism studies / Wing W. Lam ... [et al.] -- Online electrochemical-LC-MS techniques for profiling and characterizing metabolites and degradants / Paul H. Gamache ... [et al.] -- LC-MS methods with hydrogen/deuterium exchange for identification of hydroxylamine, n-oxide, and hydroxylated analogs of desloratadine / Natalia A. Penner ... [et al.] -- Turbulent-flow LC-MS: applications for accelerating pharmacokinetic profiling and metabolite identification / Joseph L. Herman and Joseph M. Di Bussolo -- Desorption ionization techniques for quantitative analysis of drug molecules / Jason S. Gobey, John Janiszewski, and Mark J. Cole -- MALDI imaging mass spectrometry for direct tissue analysis of pharmaceuticals / Yunsheng Hsieh and Walter A. Korfmacher
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