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Manual of Gastroenterology: Diagnosis and Therapy PDF

528 Pages·2008·3.567 MB·English
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79466_FM.QXD 1/8/08 4:09 PM Page i MANUAL OF GASTROENTEROLOGY: DIAGNOSIS AND THERAPY Fourth Edition 79466_FM.QXD 1/8/08 4:09 PM Page ii 79466_FM.QXD 1/8/08 4:09 PM Page iii MANUAL OF GASTROENTEROLOGY: DIAGNOSIS AND THERAPY Fourth Edition Canan Avunduk, M.D., Ph.D. Bay State Gastroenterology Melrose, Massachusetts; Clinical Associate Professor of Medicine Tufts University Medical School Boston, Massachusetts 79466_FM.QXD 1/8/08 4:09 PM Page iv Acquisitions Editor:Charles W. Mitchell Managing Editor:Sirkka Howes Project Manager:Nicole Walz Manufacturing Coordinator:Kathleen Brown Marketing Manager:Angela Panetta Design Coordinator:Terry Mallon Cover Designer: Becky Baxendell Production Services:GGS Book Services © 2008 by LIPPINCOTT WILLIAMS & WILKINS, a Wolters Kluwer business © 2002 by LIPPINCOTT WILLIAMS & WILKINS © 1994 by LIPPINCOTT–RAVEN © 1988 by LITTLE BROWN 530 Walnut Street Philadelphia, PA 19106 USA LWW.com All rights reserved. This book is protected by copyright. No part of this book may be reproduced in any form or by any means, including photocopying, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the above-mentioned copyright. Printed in the USA Library of Congress Cataloging-in-Publication Data Avunduk, Canan. Manual of gastroenterology: diagnosis and therapy/Canan Avunduk.—4th ed. p. ; cm. Includes bibliographical references and index. ISBN-13: 978-0-7817-6974-7 (pbk. : alk. Paper) 1. Gastrointestinal system— ISBN-10: 0-7817-6974-4 Diseases—Handbooks, manuals, etc. I. Title. [DNLM: 1. Gastrointestinal Diseases—diagnosis—Handbooks. 2. Gastrointestinal Diseases—therapy—Handbooks. WI 39 A963m 2008] RC801.E26 2008 616.3'3—dc22 2007028861 Care has been taken to confirm the accuracy of the information presented and to describe generally accepted practices. However, the authors, editors, and publisher are not responsible for errors or omissions or for any consequences from application of the information in this book and make no warranty, expressed or implied, with respect to the currency, completeness, or accuracy of the contents of the publication. Application of the information in a particular situation remains the professional responsibility of the practitioner. The authors, editors, and publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accordance with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new or infrequently employed drug. Some drugs and medical devices presented in this publication have Food and Drug Administration (FDA) clearance for limited use in restricted research settings. It is the responsibility of the health care provider to ascertain the FDA status of each drug or device planned for use in their clinical practice. To purchase additional copies of this book, call our customer service department at (800) 638-3030 or fax orders to (301) 223-2320. International customers should call (301) 223-2300. Visit Lippincott Williams & Wilkins on the Internet: at LWW.com. Lippincott Williams & Wilkins customer service representatives are available from 8:30 am to 6 pm. EST. 10 9 8 7 6 5 4 3 2 1 79466_FM.QXD 1/8/08 4:09 PM Page v To all my teachers and students. 79466_FM.QXD 1/8/08 4:09 PM Page vi 79466_FM.QXD 1/8/08 4:09 PM Page vii CONTENTS Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi I. APPROACH TO THE PATIENT WITH A GASTROENTEROLOGIC DISORDER 1. Social Impact of Digestive Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. The Patient’s Complaints . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 3. Examination of the Patient . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 4. Psychological and Emotional Aspects of Gastroenterologic Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 II. DIAGNOSTIC AND THERAPEUTIC PROCEDURES 5. Endoscopy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 6. Laparoscopy and Laparoscopic Surgery . . . . . . . . . . . . . . . . . . . . . . . . 25 7. Percutaneous Liver Biopsy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 8. Manometric Studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32 9. Imaging Studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37 III. NUTRITIONAL ASSESSMENT AND MANAGEMENT 10. Nutritional Requirements and Assessment . . . . . . . . . . . . . . . . . . . . . . 45 11. Enteral Nutrition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 12. Parenteral Nutrition . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 62 IV. GASTROENTEROLOGIC EMERGENCIES 13. The Acute Abdomen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77 14. Acute Gastrointestinal Bleeding . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82 15. Foreign Bodies in the Gastrointestinal Tract . . . . . . . . . . . . . . . . . . . . . 94 VII 79466_FM.QXD 1/8/08 4:09 PM Page viii VIII Contents 16. Caustic Ingestion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97 17. Fulminant Hepatic Failure and Encephalopathy . . . . . . . . . . . . . . . . . . . 102 18. Gastrointestinal and Hepatobiliary Diseases in Pregnancy . . . . . . . . . . 111 V. SPECIFIC COMPLAINTS AND DISORDERS 19. Esophageal Infections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 117 20. Gastroesophageal Reflux Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 124 21. Dysphagia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 138 22. Noncardiac Chest Pain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 147 23. Esophageal Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 152 24. Peptic Ulcer Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 156 25. Stress Ulcer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167 26. Helicobacter Pylori . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 169 27. Gastric Neoplasms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173 28. Postgastrectomy Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 178 29. Diarrhea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 182 30. Viral, Bacterial, and Parasitic Disorders of the Bowel . . . . . . . . . . . . . . 195 31. Malabsorption . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209 32. Small-Intestinal Neoplasms and Carcinoid Tumors . . . . . . . . . . . . . . . . 222 33. Irritable Bowel Syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 227 34. Intestinal Gas and Bloating . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 232 35. Diverticular Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 236 36. Constipation and Fecal Impaction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 240 37. Inflammatory Bowel Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 244 38. Vascular Disease of the Bowel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 263 39. Colonic Polyps and Colorectal Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . 269 40. Ostomy Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 280 41. Hemorrhoids and Other Anorectal Disorders . . . . . . . . . . . . . . . . . . . . . 283 42. Sexually Transmitted Enteric Disorders . . . . . . . . . . . . . . . . . . . . . . . . . 288 79466_FM.QXD 1/8/08 4:09 PM Page ix Contents IX 43. Gastrointestinal and Hepatobiliary Diseases in Patients with HIV and AIDS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 292 44. Occult Obscure Gastrointestinal Bleeding . . . . . . . . . . . . . . . . . . . . . . . 303 45. Acute Pancreatitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 306 46. Chronic Pancreatitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 317 47. Pancreatic Cancer, Ampullary Cancer, Cystic Tumors, and Neuroendocrine Tumors of the Pancreas . . . . . . . . . . . . . . . . . . . . . . . . 326 48. Jaundice and Interpretation of Laboratory Liver Tests . . . . . . . . . . . . . 335 49. Gallstones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349 50. Viral Hepatitis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 359 51. Alcoholic Liver Disease (ALD) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 386 52. Nonalcoholic Fatty Liver Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 395 53. Drug-Related Hepatic Injury . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 399 54. Chronic Immune-Mediated Liver Disease . . . . . . . . . . . . . . . . . . . . . . . . 407 55. Inherited Liver Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 421 56. Cirrhosis and Its Complications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 438 57. Tumors of the Liver and Biliary System . . . . . . . . . . . . . . . . . . . . . . . . . 455 58. Liver Transplantation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 459 59. Anorexia Nervosa and Bulimia Nervosa . . . . . . . . . . . . . . . . . . . . . . . . . 473 60. Obesity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 476 Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 484 79466_FM.QXD 1/8/08 4:09 PM Page x

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