Manual for early infant male circumcision under local anaesthesia WHO Library Cataloguing-in-Publication Data Manual for early infant male circumcision under local anaesthesia. 1.Circumcision, Male - utilization. 2.Infant, Newborn. 3.Child. 4.Manuals. 5.Anesthesia, Local. 6.HIV infections - prevention and control. I.World Health Organization. II.JHPIEGO. ISBN 978 92 4 150075 3 (NLM classification: WJ 790) © World Health Organization 2010 All rights reserved. Publications of the World Health Organization can be obtained from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; e-mail: [email protected]). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution – should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; e-mail: [email protected]). 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Printed by the WHO Document Production Services, Geneva, Switzerland Manual for early infant male circumcision under local anaesthesia Contents Abbreviations vi Definitions vi Acknowledgements 1 Photo credits 1 Purpose 2 Preface 2 Chapter 1: Male circumcision introduction 3 Chapter 2: Overview of facility and equipment requirements 9 Chapter 3: Group education and individual counselling 12 Chapter 4: Screening for early infant male circumcision 18 Chapter 5: Overview of anaesthesia 22 Chapter 6: Procedure preparation 26 Chapter 7: Overview of surgical devices 42 Chapter 8: Surgical techniques 52 Chapter 9: Postoperative care 77 Chapter 10: Postoperative complications 83 Chapter 11: Standard precautions and instrument processing 91 Chapter 12: Introduction to monitoring and evaluation 99 Chapter 13: Early infant male circumcision service delivery and programme management 103 Annex 1: Sample checklist for early infant male circumcision equipment 109 Annex 2: Sample information sheet for early infant male circumcision 110 Annex 3: Overview of counselling skills 111 Annex 4: Sample client record form for early infant male circumcision 113 Annex 5: Reported inducers of methaemoglobinaemia 114 Annex 6: Sample checklist for early infant male circumcision procedure 115 Annex 7: Sample consent form for early infant male circumcision 116 Annex 8: Sample documentation form for early infant male circumcision procedure 117 Annex 9: Overview of suturing and wound closure 118 Annex 10: Sample postoperative information sheet for early infant male circumcision 120 Annex 12: Sample postoperative bleeding protocol for early infant male circumcision 122 Annex 13: Sample register for early infant male circumcision 123 Annex 14: Sample monthly site summary form for early infant male circumcision 124 Annex 15: Essential neonatal and infant care 125 References 127 Abbreviations AIDS acquired immunodeficiency syndrome ANC antenatal care EMLA eutectic mixture of local anaesthetics HIV human immunodeficiency virus HPV human papillomavirus HSV herpes simplex virus M&E monitoring and evaluation MNCH maternal, neonatal and child health PEP post-exposure prophylaxis PMTCT prevention of mother-to-child transmission PNC postnatal care PPE personal protective equipment UNAIDS Joint United Nations Programme on HIV/AIDS UNFPA United Nations Population Fund UNICEF United Nations Children’s Fund. USAID United States Agency for International Development WHO World Health Organization Definitions early infant less than 60 days of age preterm less than 37 completed weeks of gestational age low birth weight less than 2500 g or 5 lb 9oz vi Acknowledgements This manual is the result of collaborative work between WHO and Jhpiego together with contributions from a large group of clinical and public health experts. The following people contributed to the production of the manual: • Kim Eva Dickson, Julia Samuelson (WHO, Headquarters) • Tigistu Adamu Ashengo, Kristen Chrouser, Kelly Curran, Emmanuel Otolorin (Jhpiego, USA) • Anthony Caldamone, David Tomlinson (Brown University School of Medicine, USA) Special thanks go to the international experts who participated in the Consultation on Neonatal Male Circumcision: training guidance and service delivery aspects, October 2009, for their insights and contributions to this document: • Margaret Agama (UNFPA, South Africa), Raymond Bitchong (Raleigh Fitkin Memorial Hospital, Swaziland), Kasonde Bowa (University of Zambia, Zambia), Maureen Chilila (Jhpiego, Zambia), Timothy Hargreave (BUPA Murray Field Hospital, UK), David Linyama (Centre for Infectious Disease Research, Zambia), Fabian Mwanyumba (UNICEF, Swaziland), Emmanuel Njeuhmeli (USAID, USA), Sherry Nordstrom (University of Illinois, USA), Theresa Nduku Nzomo (WHO, Regional Office for Africa), June Odoyo (University of Nairobi, Kenya), Rebeca Plank (Brigham M a and Women’s Hospital), Dino Rech (Population Services International, South Africa), David n u Sokal (Family Health International, USA), Severin Von Xylander (WHO, Headquarters) a l f o Thanks also go to the following people who contributed to the manual: r e • Christopher Bode (Lagos University Teaching Hospital, Nigeria), Jeffrey Greenwald (National a r l Naval Medical Center, USA), Ngozi Onyia (Lagos University Teaching Hospital, Nigeria), Dayo y i n Sowande (Obafemi Awolowo University Teaching Hospital, Ife, Nigeria) f a n • Jeffrey Borkan, Roger Fazio (Brown University School of Medicine, USA) t m • Olugbenga Bejide, Sister Fawole, Yemi Fawole, Cleatus Taiwo, Jeffrey Tomlinson (Catholic a l e Hospital, Ibadan, Nigeria) c i r c u Photo credits m c i s i Except where otherwise noted, the photographs have been provided by: Anthony Caldamone o n and David Tomlinson, Brown University School of Medicine, USA; and Christopher Bode, Lagos u n University Teaching Hospital, Nigeria. d e r Design and layout: Jillian Reichenbach Ott (Genève Design) lo c a l a n a e s t h e s i a 1 Purpose This manual builds on the World Health Organization’s Manual for male circumcision under local anaesthesia and focuses entirely on early infant male circumcision. It has been developed by WHO in collaboration with Jhpiego to help providers and programme managers deliver high-quality safe infant male circumcision services for the purposes of HIV prevention and other health benefits. The manual draws from experiences with service provision in Africa, the Eastern Mediterranean and developed countries and was reviewed by actual and potential providers of male circumcision services representing a range of health care and cultural settings where demand for male circumcision services is high. Preface Male circumcision is one of the oldest known surgical procedures. Egyptian records show that male circumcision was being performed as early as 2300 BC. The procedure has been adopted independently by different cultures all over the world for various medical and non-medical reasons.1 Since the mid-1980s, data from cross-sectional epidemiological studies have shown that circumcised men have a lower prevalence of HIV infection than uncircumcised men. And, over the past 5 years, three randomized controlled trials have convincingly demonstrated that male circumcision is effective in reducing female to male transmission of HIV.2, 3, 4 This opportunity for disease prevention has resulted in an increased demand for male circumcision in several countries of high HIV incidence. Guidance for adolescent and adult male circumcision services has been developed, but technical guidance is lacking on how early infant services can be safely expanded. There are significant benefits in performing male circumcision in early infancy, and programmes that promote early infant male circumcision are likely to have lower morbidity rates and lower costs than programmes targeting adolescent boys and men. 2 Chapter 1: Male circumcision introduction Summary Male circumcision is the surgical removal of all or part of the foreskin tissue (prepuce) that typically covers the tip or head of the penis. Derived from the Latin word circumcido, circumcision means, “cutting around”. During male circumcision, the foreskin is freed from the head of the penis (glans) and the foreskin is surgically excised. Figure 1.1. An uncircumcised infant penis (left) and the same penis two weeks after male circumcision (right). M a n u a l f o r e a Male circumcision is widely practised for religious and traditional reasons, often within the first r l y two weeks after birth or at the beginning of adolescence as a rite of passage into adulthood.5, 6, 7 i n f As a medical procedure, it is performed to treat problems involving the foreskin and as a means a n to help prevent some diseases. Recently, three randomized controlled trials have convincingly t m demonstrated that male circumcision reduces female to male heterosexual transmission of HIV. 8,9,10 a l e c The decision to have a newborn male circumcised is very personal and should be i r c made after careful consideration of the risks and benefits and cultural, religious, u m and personal preferences. c i s i o n The following information is provided to help families, caregivers, and health-care workers make u n an informed decision about male circumcision. d e r l o c a l a n a e s t h e s i a 3 Timing of male circumcision – infancy versus adolescence/adulthood Male circumcision can be performed at any age. Several factors should be considered when determining its timing. One important advantage of infant male circumcision is that the procedure is simpler than that performed on older boys and men because the penis is less developed and the foreskin is thinner and less vascular. Healing is quicker and complication rates are lower. The period of superficial wound healing after infant male circumcision is generally 5−7 days and most wounds heal completely within 14 days. Performing circumcision in infancy provides several other advantages: • the wound typically does not need to be sutured; • the procedure is not complicated by erections, which can be problematic in adolescent boys and men; • infant male circumcision ensures that the wound will be healed before sexual activity begins; sexual activity can complicate circumcision in adolescents and adult males and can put older patients who engage in such activity before the wound has healed at higher risk for HIV transmission. Another advantage of early infant male circumcision is the reduced risk of urinary tract infections in the first 6 months of life.11 These infections typically present with signs and symptoms of systemic involvement and can be associated with significant complications, including sepsis and renal scarring. The benefit of male circumcision in preventing urinary tract infections in the first 6 months of life cannot be realized if the procedure is delayed until after infancy. This is especially pertinent if there is an underlying uropathy, such as vesicoureteral reflux or urinary tract obstruction. A concern about early infant male circumcision is that the child cannot give informed consent for the procedure. Moreover, some of the health benefits, including reducing the risk of HIV infection, will not be realized until many years later when the person becomes sexually active. If circumcision is postponed until an older age the patient can evaluate the risks and benefits and consent to the procedure himself. Programmes that promote male circumcision in early infancy are likely to have lower morbidity rates and lower costs than programmes targeting adolescent boys and men. However, these considerations must be balanced by concerns about consent. 4
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