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Liver, Lung and Heart Regeneration PDF

220 Pages·2017·4.57 MB·English
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Stem Cells in Clinical Applications Phuc Van Pham Editor Liver, Lung and Heart Regeneration Stem Cells in Clinical Applications Series Editor Phuc Van Pham More information about this series at http://www.springer.com/series/14002 Phuc Van Pham Editor Liver, Lung and Heart Regeneration Editor Phuc Van Pham Laboratory of Stem Cell Research & Application, University of Science Vietnam National University Ho Chi Minh City, Vietnam ISSN 2365-4198 ISSN 2365-4201 (electronic) Stem Cells in Clinical Applications ISBN 978-3-319-46692-7 ISBN 978-3-319-46693-4 (eBook) DOI 10.1007/978-3-319-46693-4 Library of Congress Control Number: 2016959005 © Springer International Publishing AG 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland Preface The liver, lung and heart are major internal organs that control almost all biochemi- cal physiology activities in the human body. The liver has a broad range of physio- logical functions such as detoxification, protein synthesis and biochemical production. The lung plays the respiratory function that extracts oxygen from the atmosphere and transfers it into the bloodstream to release carbon dioxide from the bloodstream into the atmosphere. And the heart is a pump that circulates blood through the blood vessels to all tissues. With these functions, the liver, lung and heart control some organ systems including the circulatory system, respiratory sys- tem, digestive system, urinary system, etc. Therefore, any diseases that relate to these organs can cause extreme health conditions. There are two main groups of diseases related to these organs: infectious dis- eases and degenerative diseases (failure). Although there are different symptoms, they result from the significant loss of functional tissue cells. The regeneration of these functional tissue cells is considered a promising therapy to treat these conditions. In recent years, stem cell therapies for liver, lung and heart regeneration are moved to the clinic with exciting results. Although there are some kinds of stem cells, including both pluripotent stem cells (induced pluripotent stem cells, embry- onic stem cells) and adult stem cells used in the preclinical trials (in animals), a majority of clinical applications used mesenchymal stem cells—a kind of adult stem cells. Mesenchymal stem cells are used with two strategies including immune modulation and cell replacement. Indeed, some studies showed that mesenchymal stem cells could inhibit the inflammation in liver cirrhosis or are differentiated into the functional cells to replace the dead cells in ischemic heart disease. This volume of “Stem Cells in Clinical Applications” book series with title Liver, Lung and Heart Regeneration aims to provide updated invaluable resource for advanced undergraduate students, graduate students, researchers and clinicians in stem cell applications for liver, lung and heart regeneration. The book with 11 chapters covers almost the present applications of stem cells in liver, lung and heart regeneration. Chapters 1–4 discuss about liver regeneration. As the most popular liver disease, liver cirrhosis was treated by stem cell transplantation v vi Preface that is presented in Chaps. 2 and 3. And the mechanism of stem cell therapy for liver cirrhosis treatment also is suggested in Chap. 4. Chapters 5–7 discuss about applica- tions of stem cells in lung regeneration. Both airway and lung regeneration are stated in Chaps. 5–7, respectively. And Chaps. 8–11 discuss about stem cell therapy and tissue engineering for heart regeneration. We are indebted to our authors who graciously accepted their assignments and who have infused the text with their energetic contributions. We are incredibly thankful to the staff of Springer Science+Business Media who published this book. Ho Chi Minh City, Vietnam Phuc Van Pham Contents Part I Liver Regeneration 1 Characteristics of Hepatic Progenitor Cells During Liver Development and Regeneration................................................... 3 Akihide Kamiya and Hiromi Chikada 2 Cell Therapy in Chronic Liver Disease ................................................. 15 Majid Alhomrani, Rebecca Lim, and William Sievert 3 Clinical Applications of Stem Cells in Liver Cirrhosis ........................ 41 Ahmer Irfan 4 Mesenchymal Stem Cell Therapy for Liver Cirrhosis Treatment: Mechanisms and Bioeffects .................................................................... 51 Nhung Hai Truong and Phuc Van Pham Part II Lung Regeneration 5 Mesenchymal Stem Cell Therapy for Airway Restoration Following Surgery ................................................................................... 69 Francesco Petrella, Stefania Rizzo, Fabio Acocella, Stefano Brizzola, and Lorenzo Spaggiari 6 Regenerative Potential of Mesenchymal Stem Cells: Therapeutic Applications in Lung Disorders ....................................... 77 Kavita Sharma, Syed Yawer Husain, Pragnya Das, Mohammad Hussain, and Mansoor Ali Syed 7 Recent Advances in Lung Regeneration ............................................... 119 Kanwal Rehman and Muhammad Sajid Hamid Akash vii viii Contents Part III Heart Regeneration 8 Road to Heart Regeneration with Induced Pluripotent Stem Cells ................................................................................................ 137 Jun Fujita, Shugo Tohyama, Kazuaki Nakajima, Tomohisa Seki, Hideaki Kanazawa, and Keiichi Fukuda 9 Myocardial Tissue Engineering for Cardiac Repair............................ 153 S. Pecha and Y. Yildirim 10 Stem Cell Therapy for Ischemic Heart Disease .................................... 165 Truc Le-Buu Pham, Ngoc Bich Vu, and Phuc Van Pham 11 Myocardial Tissue Engineering: A 5 Year—Update ............................ 197 Marie-Noelle Giraud and Inês Borrego Index ................................................................................................................. 211 Contributors Fabio Acocella Department of Health, Animal Science and Public Health, University of Milan, Milan, Italy Muhammad Sajid Hamid Akash Department of Pharmaceutical Chemistry, Government College University, Faisalabad, Pakistan Majid Alhomrani Centre for Inflammatory Disease, Monash University, Melbourne, VIC, Australia Hudson Institute of Medical Research, Melbourne, VIC, Australia Medical College, Taif University, Taif, Saudi Arabia Inês Borrego Department of Medicine, Cardiology, University of Fribourg, Fribourg, Switzerland Stefano Brizzola Department of Health, Animal Science and Public Health, University of Milan, Milan, Italy Hiromi Chikada Department of Molecular Life Sciences, Tokai University School of Medicine, Isehara, Kanagawa, Japan Pragnya Das Drexel University School of Medicine, Philadelphia, PA, USA Jun Fujita Department of Cardiology, Keio University School of Medicine, Tokyo, Japan Keiichi Fukuda Department of Cardiology, Keio University School of Medicine, Tokyo, Japan Marie-Noelle Giraud Department of Medicine, Cardiology, University of Fribourg, Fribourg, Switzerland Syed Yawer Husain Stem Cell Research Lab, Rajasthan University of Health Sciences, Rajasthan, India ix x Contributors Mohammad Hussain Department of Biotechnology, Jamia Millia Islamia (Central University), New Delhi, India Ahmer Irfan University of Edinburgh, Edinburgh, UK Akihide Kamiya Department of Molecular Life Sciences, Tokai University School of Medicine, Isehara, Kanagawa, Japan Hideaki Kanazawa Department of Cardiology, Keio University School of Medicine, Tokyo, Japan Rebecca Lim Department of Obstetrics and Gynaecology, Monash University, Melbourne, VIC, Australia Hudson Institute of Medical Research, Melbourne, VIC, Australia Kazuaki Nakajima Department of Cardiology, Keio University School of Medicine, Tokyo, Japan S. Pecha Department of Cardiovascular Surgery, University Heart Center Hamburg, Hamburg, Germany DZHK (German Centre for Cardiovascular Research) Partner Site Hamburg/Kiel/ Lübeck, Lübeck, Germany Francesco Petrella Department of Thoracic Surgery, European Institute of Oncology, Milan, Italy Truc Le-Buu Pham Laboratory of Stem Cell Research and Application, University of Science, Vietnam National University, Ho Chi Minh City, Vietnam Phuc Van Pham Laboratory of Stem Cell Research and Application, University of Science, Vietnam National University, Ho Chi Minh City, Vietnam Kanwal Rehman Institute of Pharmacy, Physiology and Pharmacology, University of Agriculture, Faisalabad, Pakistan Stefania Rizzo Department of Radiology, European Institute of Oncology, Milan, Italy Tomohisa Seki Department of Cardiology, Keio University School of Medicine, Tokyo, Japan Kavita Sharma Department of Pathology, AIIMS, New Delhi, India William Sievert Gastroenterology and Hepatology Unit, Monash Health, and Department of Medicine, Monash University, Melbourne, VIC, Australia Centre for Inflammatory Disease, Monash University, Melbourne, VIC, Australia Lorenzo Spaggiari Department of Thoracic Surgery, European Institute of Oncology, Milan, Italy School of Medicine, University of Milan, Milan, Italy

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