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Liver imaging: MRI with CT correlation CurrentClinicalImagingSeries SeriesEditor–RichardC.Semelka VascularImagingoftheCentralNervousSystem:PhysicalPrinciples,ClinicalApplicationsandEmergingTechniques; JoanaRamalho,MauricioCastillo,2014 OtherbooksintheSeries ImagingMSKTrauma;AndreaDonovan,MarkE.Schweitzer,2012 HealthCareReforminRadiology;RichardC.Semelka,JorgeElias,2013 TextAtlasofSkeletalAgeDetermination;ErnestoTomei,RichardC.Semelka,DanielNissman,2014 Women’sImaging;MicheleA.Brown,HaydeeOjeda-Fournier,DraganaDjilas,MohamedEl-Azzazi,RichardC.Semelka,2014 Liver imaging: MRI with CT correlation Editors Ersan Altun MD AssociateProfessorofRadiology, AttendingRadiologist, AbdominalImaging,DepartmentofRadiology, TheUniversityofNorthCarolinaatChapelHill,NC,USA Mohamed El-Azzazi MD, PhD AssociateProfessorofRadiology UniversityofDammam,DepartmentofRadiology,SaudiArabia; ConsultantintheDepartmentofRadiology KingFahdHospitaloftheUniversity,SaudiArabia; AssistantProfessorofRadiology UniversityofAlAzhar,Cairo,Egypt; ClinicalResearchScholar DepartmentofRadiology,UniversityofNorthCarolina,ChapelHill,NC,USA Richard C. Semelka MD ProfessorofRadiology AbdominalImaging,DepartmentofRadiology DirectorofMRIServices ViceChairofQualityandSafety TheUniversityofNorthCarolinaatChapelHill,NC,USA Thiseditionfirstpublished2015©2015byJohnWiley&Sons,Inc. Registeredoffice: JohnWiley&Sons,Ltd,TheAtrium,SouthernGate,Chichester,WestSussex,PO198SQ,UK Editorialoffices: 9600GarsingtonRoad,Oxford,OX42DQ,UK TheAtrium,SouthernGate,Chichester,WestSussex,PO198SQ,UK 111RiverStreet,Hoboken,NJ07030-5774,USA Fordetailsofourglobaleditorialoffices,forcustomerservicesandforinformationabouthowtoapplyforpermissiontoreuse thecopyrightmaterialinthisbookpleaseseeourwebsiteatwww.wiley.com/wiley-blackwell TherightoftheauthortobeidentifiedastheauthorofthisworkhasbeenassertedinaccordancewiththeUKCopyright, DesignsandPatentsAct1988. Allrightsreserved.Nopartofthispublicationmaybereproduced,storedinaretrievalsystem,ortransmitted,inanyformor byanymeans,electronic,mechanical,photocopying,recordingorotherwise,exceptaspermittedbytheUKCopyright, DesignsandPatentsAct1988,withoutthepriorpermissionofthepublisher. Designationsusedbycompaniestodistinguishtheirproductsareoftenclaimedastrademarks.Allbrandnamesandproduct namesusedinthisbookaretradenames,servicemarks,trademarksorregisteredtrademarksoftheirrespectiveowners.The publisherisnotassociatedwithanyproductorvendormentionedinthisbook.Itissoldontheunderstandingthatthe publisherisnotengagedinrenderingprofessionalservices.Ifprofessionaladviceorotherexpertassistanceisrequired,the servicesofacompetentprofessionalshouldbesought. Thecontentsofthisworkareintendedtofurthergeneralscientificresearch,understanding,anddiscussiononlyandarenot intendedandshouldnotberelieduponasrecommendingorpromotingaspecificmethod,diagnosis,ortreatmentbyhealth sciencepractitionersforanyparticularpatient.Thepublisherandtheauthormakenorepresentationsorwarrantieswith respecttotheaccuracyorcompletenessofthecontentsofthisworkandspecificallydisclaimallwarranties,includingwithout limitationanyimpliedwarrantiesoffitnessforaparticularpurpose.Inviewofongoingresearch,equipmentmodifications, changesingovernmentalregulations,andtheconstantflowofinformationrelatingtotheuseofmedicines,equipment,and devices,thereaderisurgedtoreviewandevaluatetheinformationprovidedinthepackageinsertorinstructionsforeach medicine,equipment,ordevicefor,amongotherthings,anychangesintheinstructionsorindicationofusageandforadded warningsandprecautions.Readersshouldconsultwithaspecialistwhereappropriate.Thefactthatanorganizationor Websiteisreferredtointhisworkasacitationand/orapotentialsourceoffurtherinformationdoesnotmeanthattheauthor orthepublisherendorsestheinformationtheorganizationorWebsitemayprovideorrecommendationsitmaymake. Further,readersshouldbeawarethatInternetWebsiteslistedinthisworkmayhavechangedordisappearedbetweenwhen thisworkwaswrittenandwhenitisread.Nowarrantymaybecreatedorextendedbyanypromotionalstatementsforthis work.Neitherthepublishernortheauthorshallbeliableforanydamagesarisingherefrom. LibraryofCongressCataloging-in-PublicationData Liverimaging:MRIwithCTcorrelation/editors,ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka. p.;cm. Includesbibliographicalreferencesandindex. ISBN978-0-470-90625-5(hardback) I.Altun,Ersan,1975-,editor.II.El-Azzazi,Mohamed,editor.III.Semelka,RichardC.,editor. [DNLM:1. LiverDiseases–diagnosis.2. Diagnosis,Differential.3. Imaging,Three-Dimensional.4. MagneticResonance Imaging.5. Tomography,X-RayComputed.WI700] RC847 616.3′620757–dc23 2014049427 AcataloguerecordforthisbookisavailablefromtheBritishLibrary. Wileyalsopublishesitsbooksinavarietyofelectronicformats.Somecontentthatappearsinprintmaynotbeavailablein electronicbooks. Typesetin9.5/12ptMinionProbyLaserwordsPrivateLimited,Chennai,India 1 2015 Contents ListofContributors,vii 8 RarePrimaryandSecondaryTumorsoftheLiver,181 ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka Preface,ix 9 Cholangiocarcinoma,193 1 TheCross-SectionalAnatomyoftheLiverand ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka, NormalVariations,1 andMiguelRamalho ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka 10 InfectiousDiseasesoftheLiver,201 2 TheCross-SectionalImagingTechniquesand ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka DiagnosticApproach,15 ErsanAltunandRichardC.Semelka 11 ChronicHepatitisandLiverCirrhosis,219 ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka, 3 SafetyofMRIandCT,63 andMamdohAlObaidy ErsanAltunandRichardC.Semelka 12 HepaticFatandIronDeposition,241 4 CysticDiseasesoftheLiver,73 ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka ErsanAltun,Mohamed,El-Azzazi,RichardC.Semelka, andMiguelRamalho 13 InflammatoryLiverDiseases,255 ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka 5 BenignSolidLiverLesions,101 ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka, 14 VascularDisordersoftheLiver,267 andMamdohAlObaidy ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka 6 LiverMetastases,137 15 Post-treatmentChangesintheLiver,285 ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka, ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka andMiguelRamalho 16 LiverTrauma,301 7 HepatocellularCarcinoma,161 ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka, Index,305 andMamdohAlObaidy v List of Contributors Mamdoh AlObaidy KingFahdHospitaloftheUniversity,DepartmentofRadiology, TheUniversityofNorthCarolinaatChapelHill,Departmentof Khobar,SaudiArabia Radiology,ChapelHill,NC,USA University of Al Azhar, Department of Radiology, Cairo, KingFaisalSpecialistHospital&ResearchCenter,Department Egypt ofRadiology,Riyadh,SaudiArabia Miguel Ramalho Ersan Altun TheUniversityofNorthCarolinaatChapelHill,Departmentof TheUniversityofNorthCarolinaatChapelHill,Departmentof Radiology,ChapelHill,NC,USA Radiology,ChapelHill,NC,USA Hospital Garcia de Orta, Department of Radiology, Almada, Portugal Mohamed El-Azzazi TheUniversityofNorthCarolinaatChapelHill,Departmentof Richard C. Semelka Radiology,ChapelHill,NC,USA TheUniversityofNorthCarolinaatChapelHill,Departmentof UniversityofDammam,DepartmentofRadiology,Dammam, Radiology,ChapelHill,NC,USA SaudiArabia vii

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The first single source work to deal with the two primary radiologic modalities in diagnosing and treating benign and malignant diseases of the liver, presented with clearly laid out MRI and CT correlations. Developed by an editor team led by one of the world’s leading authorities in abdominal ima
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Liver imaging: MRI with CT correlation CurrentClinicalImagingSeries SeriesEditor–RichardC.Semelka VascularImagingoftheCentralNervousSystem:PhysicalPrinciples,ClinicalApplicationsandEmergingTechniques; JoanaRamalho,MauricioCastillo,2014 OtherbooksintheSeries ImagingMSKTrauma;AndreaDonovan,MarkE.Schweitzer,2012 HealthCareReforminRadiology;RichardC.Semelka,JorgeElias,2013 TextAtlasofSkeletalAgeDetermination;ErnestoTomei,RichardC.Semelka,DanielNissman,2014 Women’sImaging;MicheleA.Brown,HaydeeOjeda-Fournier,DraganaDjilas,MohamedEl-Azzazi,RichardC.Semelka,2014 Liver imaging: MRI with CT correlation Editors Ersan Altun MD AssociateProfessorofRadiology, AttendingRadiologist, AbdominalImaging,DepartmentofRadiology, TheUniversityofNorthCarolinaatChapelHill,NC,USA Mohamed El-Azzazi MD, PhD AssociateProfessorofRadiology UniversityofDammam,DepartmentofRadiology,SaudiArabia; ConsultantintheDepartmentofRadiology KingFahdHospitaloftheUniversity,SaudiArabia; AssistantProfessorofRadiology UniversityofAlAzhar,Cairo,Egypt; ClinicalResearchScholar DepartmentofRadiology,UniversityofNorthCarolina,ChapelHill,NC,USA Richard C. Semelka MD ProfessorofRadiology AbdominalImaging,DepartmentofRadiology DirectorofMRIServices ViceChairofQualityandSafety TheUniversityofNorthCarolinaatChapelHill,NC,USA Thiseditionfirstpublished2015©2015byJohnWiley&Sons,Inc. Registeredoffice: JohnWiley&Sons,Ltd,TheAtrium,SouthernGate,Chichester,WestSussex,PO198SQ,UK Editorialoffices: 9600GarsingtonRoad,Oxford,OX42DQ,UK TheAtrium,SouthernGate,Chichester,WestSussex,PO198SQ,UK 111RiverStreet,Hoboken,NJ07030-5774,USA Fordetailsofourglobaleditorialoffices,forcustomerservicesandforinformationabouthowtoapplyforpermissiontoreuse thecopyrightmaterialinthisbookpleaseseeourwebsiteatwww.wiley.com/wiley-blackwell TherightoftheauthortobeidentifiedastheauthorofthisworkhasbeenassertedinaccordancewiththeUKCopyright, DesignsandPatentsAct1988. Allrightsreserved.Nopartofthispublicationmaybereproduced,storedinaretrievalsystem,ortransmitted,inanyformor byanymeans,electronic,mechanical,photocopying,recordingorotherwise,exceptaspermittedbytheUKCopyright, DesignsandPatentsAct1988,withoutthepriorpermissionofthepublisher. Designationsusedbycompaniestodistinguishtheirproductsareoftenclaimedastrademarks.Allbrandnamesandproduct namesusedinthisbookaretradenames,servicemarks,trademarksorregisteredtrademarksoftheirrespectiveowners.The publisherisnotassociatedwithanyproductorvendormentionedinthisbook.Itissoldontheunderstandingthatthe publisherisnotengagedinrenderingprofessionalservices.Ifprofessionaladviceorotherexpertassistanceisrequired,the servicesofacompetentprofessionalshouldbesought. Thecontentsofthisworkareintendedtofurthergeneralscientificresearch,understanding,anddiscussiononlyandarenot intendedandshouldnotberelieduponasrecommendingorpromotingaspecificmethod,diagnosis,ortreatmentbyhealth sciencepractitionersforanyparticularpatient.Thepublisherandtheauthormakenorepresentationsorwarrantieswith respecttotheaccuracyorcompletenessofthecontentsofthisworkandspecificallydisclaimallwarranties,includingwithout limitationanyimpliedwarrantiesoffitnessforaparticularpurpose.Inviewofongoingresearch,equipmentmodifications, changesingovernmentalregulations,andtheconstantflowofinformationrelatingtotheuseofmedicines,equipment,and devices,thereaderisurgedtoreviewandevaluatetheinformationprovidedinthepackageinsertorinstructionsforeach medicine,equipment,ordevicefor,amongotherthings,anychangesintheinstructionsorindicationofusageandforadded warningsandprecautions.Readersshouldconsultwithaspecialistwhereappropriate.Thefactthatanorganizationor Websiteisreferredtointhisworkasacitationand/orapotentialsourceoffurtherinformationdoesnotmeanthattheauthor orthepublisherendorsestheinformationtheorganizationorWebsitemayprovideorrecommendationsitmaymake. Further,readersshouldbeawarethatInternetWebsiteslistedinthisworkmayhavechangedordisappearedbetweenwhen thisworkwaswrittenandwhenitisread.Nowarrantymaybecreatedorextendedbyanypromotionalstatementsforthis work.Neitherthepublishernortheauthorshallbeliableforanydamagesarisingherefrom. LibraryofCongressCataloging-in-PublicationData Liverimaging:MRIwithCTcorrelation/editors,ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka. p.;cm. Includesbibliographicalreferencesandindex. ISBN978-0-470-90625-5(hardback) I.Altun,Ersan,1975-,editor.II.El-Azzazi,Mohamed,editor.III.Semelka,RichardC.,editor. [DNLM:1. LiverDiseases–diagnosis.2. Diagnosis,Differential.3. Imaging,Three-Dimensional.4. MagneticResonance Imaging.5. Tomography,X-RayComputed.WI700] RC847 616.3′620757–dc23 2014049427 AcataloguerecordforthisbookisavailablefromtheBritishLibrary. Wileyalsopublishesitsbooksinavarietyofelectronicformats.Somecontentthatappearsinprintmaynotbeavailablein electronicbooks. Typesetin9.5/12ptMinionProbyLaserwordsPrivateLimited,Chennai,India 1 2015 Contents ListofContributors,vii 8 RarePrimaryandSecondaryTumorsoftheLiver,181 ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka Preface,ix 9 Cholangiocarcinoma,193 1 TheCross-SectionalAnatomyoftheLiverand ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka, NormalVariations,1 andMiguelRamalho ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka 10 InfectiousDiseasesoftheLiver,201 2 TheCross-SectionalImagingTechniquesand ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka DiagnosticApproach,15 ErsanAltunandRichardC.Semelka 11 ChronicHepatitisandLiverCirrhosis,219 ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka, 3 SafetyofMRIandCT,63 andMamdohAlObaidy ErsanAltunandRichardC.Semelka 12 HepaticFatandIronDeposition,241 4 CysticDiseasesoftheLiver,73 ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka ErsanAltun,Mohamed,El-Azzazi,RichardC.Semelka, andMiguelRamalho 13 InflammatoryLiverDiseases,255 ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka 5 BenignSolidLiverLesions,101 ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka, 14 VascularDisordersoftheLiver,267 andMamdohAlObaidy ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka 6 LiverMetastases,137 15 Post-treatmentChangesintheLiver,285 ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka, ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka andMiguelRamalho 16 LiverTrauma,301 7 HepatocellularCarcinoma,161 ErsanAltun,MohamedEl-Azzazi,andRichardC.Semelka ErsanAltun,MohamedEl-Azzazi,RichardC.Semelka, Index,305 andMamdohAlObaidy v List of Contributors Mamdoh AlObaidy KingFahdHospitaloftheUniversity,DepartmentofRadiology, TheUniversityofNorthCarolinaatChapelHill,Departmentof Khobar,SaudiArabia Radiology,ChapelHill,NC,USA University of Al Azhar, Department of Radiology, Cairo, KingFaisalSpecialistHospital&ResearchCenter,Department Egypt ofRadiology,Riyadh,SaudiArabia Miguel Ramalho Ersan Altun TheUniversityofNorthCarolinaatChapelHill,Departmentof TheUniversityofNorthCarolinaatChapelHill,Departmentof Radiology,ChapelHill,NC,USA Radiology,ChapelHill,NC,USA Hospital Garcia de Orta, Department of Radiology, Almada, Portugal Mohamed El-Azzazi TheUniversityofNorthCarolinaatChapelHill,Departmentof Richard C. Semelka Radiology,ChapelHill,NC,USA TheUniversityofNorthCarolinaatChapelHill,Departmentof UniversityofDammam,DepartmentofRadiology,Dammam, Radiology,ChapelHill,NC,USA SaudiArabia vii

Description:
The first single source work to deal with the two primary radiologic modalities in diagnosing and treating benign and malignant diseases of the liver, presented with clearly laid out MRI and CT correlations. Developed by an editor team led by one of the world’s leading authorities in abdominal ima
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