Liver Cancer

386 Pages·1985·10.19 MB·English

by  Zachary D. Goodman

LIVER CANCER
DEVELOPMENTS IN ONCOLOGY
F.J. Cleton and J.W.I.M. Simons, eds.: Genetic Origins of Tumour Cells. 90-247-2272-1.
J. Aisner and P. Chang, cds.: Cancer Treatment and Research. 90-247-2358-2.
B.W. Ongerboer de Visser, D.A. Bosch and W.M.H. van Woerkom-Eykenboom, eds.: Neuro-oncology: Clinical
and Experimental Aspects. 90-247-2421-X.
K. Hellmann, P. Hilgard and S. Eccles, eds.: Metastasis: Clinical and Experimental Aspects. 90-247-2424-4.
H.F. Seigler, ed.: Clinical Management of Melanoma. 90-247-2584-4.
P. Correa and W. Haenszel, eds.: Epidemiology of Cancer of the Digestive Tract. 90-247-2601-8.
L.A. Liotta and I.R. Hart, eds.: Tumour Invasion and Metastasis. 90-247-2611-5.
J. Banoczy, ed.: Oral Leukoplakia. 90-247-2655-7.
C. Tijssen, M. Halprin and L. Endtz, eds.: Familial Brain Tumours. 90-247-2691-3.
F.M. Muggia, C.W. Young and S.K. Carter, eds.: Anthracycline Antibiotics in Cancer. 90-247-2711-1.
B.W. Hancock, ed.: Assessment of Tumour Response. 90-247-2712-X.
D.E. Peterson and S. Sonis, cds.: Oral Complications of Cancer Chemotherapy. 0-89838-563-6.
R. Mastrangelo, D.G. Pop lack and R. Riccardi, eds.: Central Nervous System Leukemia. Prevention and
Treatment. 0-89838-570-9.
'\. Polliack, cd.: Human Leukemias. Cytochemical and Ultrastructural Techniques in Diagnosis and Research.
0-89838-585-7.
W. Davis, C. Maltoni and S. Tanneberger, eds.: The Control of Tumor Growth and its Biological Bases.
0-89838-603-9.
A.P.M. Heintz, C. Th. Griffiths and J.B. Trimbos, eds.: Surgery in Gynecological Oncology. 0-89838-604-7.
M.P. Hacker, E.B. Douple and I. Krakoff, cds.: Platinum Coordination Complexes in Cancer Chemotherapy.
0-89838-619-5.
MJ. van Zwieten. The Rat as Animal Model in Breast Cancer Research: A Histopathological Study of Radiation-
and Hormone-Induced Rat Mammary Tumors. 0-89838-624-1.
B. Lowenberg and A. Hogenbeck, eds.: Minimal Residual Disease in Acute Leukemia. 0-89838-630-6.
I. van der Waal and G.B. Snow, eds.: Oral Oncology. 0-89838-631-4.
B.W. Hancock and A.M. Ward, eds.: Immunological Aspects of Cancer. 0-89838-664-0.
K.V. Honn and B.F. Sloane, cds.: Hemostatic Mechanisms and Metastasis. 0-89838-667-5.
K.R. Harrap, W. Davis and A.N. Calvert, eds.: Cancer Chemotherapy and Selective Drug Development.
0-89838-673-X.
V.D. Velde, J.H. Come lis and P.H. Sugarbaker, eds.: Liver Metastasis. 0-89838-648-5.
D.J. Ruiter, K. Welvaart and S. Ferrone, cds.: Cutaneous Melanoma and Precursor Lesions. 0-89838-689-6.
S.B. Howell, ed.: Intra-Arterial and Intracavitary Cancer Chemotherapy. 0-89838-691-8.
D.L. Kisner and J.F. Smyth, eds.: Interferon Alpha-2: Pre-Clinical and Clinical Evaluation. 0-89838-701-9.
P. Furmanski,J.C. Hager and M.A. Rich, eds.: RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On
the Frontiers of Understanding. 0-89838-703-5.
J.E. Talmadge, I.J. Fidler and R.K. Oldham: Screening for Biological Response Modifiers: Methods and Ratio
nale. 0-89838-712-4.
J.c. Bottino, R.W. Opfell and F.M. Muggia, eds.: Liver Cancer. 0-89R38-713-2.
P.K. Pattengale, R.J. Lukes and C.R. Taylor, cds.: Lymphoproliferative Diseases: Pathogenesis, Diagnosis, Ther
apy. 0-89838-725-6.
F. Cavalli, G. Bonadonna and M. Rozencweig, eds.: Malignant Lymphomas and Hodgkin's Disease. 0-89838-
727-2.
LIVER CANCER
EDITED BY
JOSEPH C. BOTTINO
New York University Medical Center
RICHARD W. OPFELL
University of California, Irvine Medical Center
FRANCO M. MUGGIA
New York University Medical Center
u
"
MARTINUS NIJHOFF PUBLISHING
A MEMBER OF THE KLUWER ACADEMIC PUBLISHERS GROUP
BOSTON /DORDRECHT /LANCASTER
Copyright 1985 @ by Martinus Nijhoff Publishing, Boston
Softcover reprint of the hardcover 1st edition 1985
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system,
or transmitted in any fortn or by any means, mechanical, photocopying, recording, or otherwise,
without written permission of the publisher, Martinus Nijhoff Publishing, 190 Old Derby Street,
Hingham, Massachusetts 02043.
Distributors for North America: Distributors for all other countries:
Kluwer Academic Publishers Kluwer Academic Publishers Group
190 Old Derby Street Distribution Centre
Hingham, MA 02043 P.O. Box 322
3300 AH Dordrecht
The Netherlands
Library of Congress Cataloging-in-Publication Data
Main entry under title:
Liver cancer.
(Developments in oncology)
1. Liver Cancer. I. Bottino, Joseph c., 1947-
II. Opfell, Richard W. III. Muggia, Franco M.
[DNLM: 1. Liver Neoplasms-therapy.
WI DE998N / WI 735 L7817]
RC280.L5L575 1985 616.99'436 85-7217
ISBN-13: 978-1-4612-9625-6 e-ISBN-13: 978-1-4613-2593-2
DOl: 10.1007/978-1-4613-2593-2
CONTENTS
Contributing authors VB
Preface xv
I. PATHOLOGY AND NATURAL HISTORY
1. Pathology of liver tumors 3
Z.D. GOODMAN AND K.G. ISHAK
2. Natural history of liver cancer 21
G. FALKSON AND B. COETZER
II. DIAGNOSIS OF LIVER CANCER
3. Radiologic techniques for detection and evaluation of liver cancer 35
E. LEWIS AND S. WALLACE
4. Nuclear medicine aspects of primary and secondary liver cancer 69
J.W. FROELICH, J.H. THRALL, AND D.P. SWANSON
III. SURGERY IN LIVER CANCER
5. Surgical anatomy of the liver and biliary tree 87
D.M. NAGORNEY AND J.A. VAN HEERDEN
6. Surgical therapy of liver cancer 99
R. OTTOW, D.A. AUGUST, AND P.H. SUGARBAKER
7. Hepatic artery ligation for liver cancer 143
N.J. PETRELLI AND A. MITTLEMAN
v
vi Contents
8. Hepatic artery embolization for liver cancer 157
c. CHARNSANGAVEJ, S. WALLACE, C.H. CARRASCO, AND W. BECHTEL
9. Surgical aspects of intrahepatic artery therapy 179
J.E. NIEDERHUBER
IV. CHEMOTHERAPY OF LIVER CANCER
10. Chemotherapy of liver cancer 197
J.J. LOKICH
11. New chemotherapeutic agents in liver cancer 217
F.M. MUGGIA AND M.D. GREEN
12. Intraperitoneal chemotherapy: a possible role in the treatment of hepatic
metastases 225
J.L. SPEYER
13. Pharmacologic studies of hepatic intra-arterial chemotherapy 237
w.o. ENSMINGER AND J.W. GYVES
14. Regional chemotherapy of liver cancer 247
R.W. OPFELL AND J. BOWEN
15. Regional arterial therapy in the management of primary liver neoplasms 263
Y.Z. PATT, c. CHARNSANGEVEJ, M. SOSKI, AND G.M. MAVLIGIT,
16. Pumps and catheters for intrahepatic artery therapy 275
J.C. BOTTINO
17. Adjuvant therapy for prevention of liver metastases 285
H.W. BRUCKNER
V. RADIATION THERAPY OF LIVER CANCER
18. Radiation therapy of hepatobiliary tumors 297
S.A. LEIBEL
VI. COMBINED MODALITY THERAPY
19. Combination chemotherapy and whole liver irradiation for hepatic tumors 315
M.A. FRIEDMAN
20. Therapy of metastatic carcinoid tumor and the carcinoid syndrome 325
C.G. MOERTEL
21. Regional-arterial chemotherapy or arterial embolization in the management of
various stages of colon cancer 341
Y. PATT, c. CHARSANGAVEJ, A. BODDIE, G.M. MAVLIGIT, M. SOSKI, AND S. WALLACE
22. Thermochemotherapy of liver metastases 357
K.P. RAMMING AND F. K STORM
23. Combined hepatic arterial occlusion and chemotherapy for primary or secondary
tumors of the liver 371
C.P. KARAKOUSIS
Index 387
CONTRIBUTING AUTHORS
David A. August, M.D.
Department of Surgery
Yale University School of Medicine
333 Cedar Street
New Haven, CT 06510
William Bechtel, M.D.
Department of Diagnostic Radiology
The University of Texas
M.D. Anderson Hospital and Tumor Institute
6723 Bertner A venue
Houston, TX 77030
A. Boddie, M.D.
Department of Surgery
The University of Texas System Cancer Center
M.D. Anderson Hospital and Tumor Institute
6723 Bertner Avenue
Houston, TX 77030
Vll
viii Contributing authors
Joseph C. Bottino, M.D.
Rita and Stanley H. Kaplan Cancer Center
New York University Medical Center
550 First Avenue
New York, NY 10016
Joseph Bowen, M.D.
Suite 30
80 Phoenix A venue
Waterbury, CT 06702
Howard W. Bruckner, M.D.
Medicine (Oncology) and Neoplastic Diseases
Mount Sinai School of Medicine
1 Gustave Levy Place
New York, NY
C. Humberto Carrasco, M.D.
Department of Diagnostic Radiology
The University of Texas
M.D. Anderson Hospital and Tumor Institute
6723 Bertner Avenue
Houston, TX 77030
Chusilp Charnsangavej, M.D.
Department of Diagnostic Radiology
The University of Texas
M.D. Anderson Hospital and Tumor Institute
6723 Bertner Avenue
Houston, TX 77030
Buks Coetzer, M.D.
Department of Cancer Chemotherapy
HF Verwoerd Hospital and University of Pretoria
Private Bag x169
Pretoria, 0001 Republic of South Africa
William D. Ensminger, Ph.D., M.D.
University of Michigan Medical School
Upjohn Center for Clinical Pharmacology
Ann Arbor, MI 48109
ix
Geoffrey Falkson, M.D.
Department of Cancer Chemotherapy
HF Verwoerd Hospital and University of Pretoria
Private Bag x169
Pretoria, 0001 Republic of South Africa
Michael A. Friedman, M.D.
Clinical Investigations Branch
Division of Cancer Treatment
National Cancer Institute
Bethesda, MD 20205
Jerry W. Froelich, M.D.
Henry Ford Hospital
Department of Radiology
Detroit, MI 48202
Zachary D. Goodman, MAJ, MC, USA
Department of Hepatic Pathology
Armed Forces Institute of Pathology
Washington, DC 20306
Michael Green, M.D.
Rita & Stanley H. Kaplan Cancer Center
New York University Medical Center
550 First Avenue
New York, NY 10016
John W. Gyves, M.D.
Cancer Pharmacology Program
University of Michigan Medical School
Upjohn Center for Clinical Pharmacology
Ann Arbor, MI 48109
Kamal G. Ishak, M.D., ph.D.
Department of Hepatic Pathology
Armed Forces Institute of Pathology
Washington, DC 20306
Constantine P. Karakousis, M.D.
Department of Surgical Oncology
New York State Department of Health
Roswell Park Memorial Institute
x Contributing authors
666 Elm Street
Buffalo, NY 14263
Steven Leibel, M.D.
Department of Radiation Oncology
University of California
San Francisco, CA 94143
Errol Lewis, M.D.
Department of Diagnostic Radiology
The University of Texas
M.D. Anderson Hospital and Tumor Institute
6723 Bertner Avenue
Houston, TX 77030
Jacob J. Lokich, M.D.
Section of Medical Oncology
New England Deaconess Hospital
Harvard Medical School
Boston, MA 02115
Giora M. Mavligit, M.D.
Department of Clinical Immunology and Biological Therapy
The University of Texas System Cancer Center
M.D. Anderson Hospital and Tumor Institute
6723 Bertner Avenue
Houston, TX 77030
Arnold Mittelman, M.D.
Department of Surgery
Roswell Park Memorial Institute
666 Elm Street
Buffalo, NY 14263
Charles G. Moertel, M.D.
Mayo Clinic and Mayo Foundation
Rochester, MN 55905
Franco M. Muggia, M.D.
Rita & Stanley H. Kaplan Cancer Center
New York University Medical Center
550 First Avenue
New York, NY 10016