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Lithium in Neuropsychiatry: The Comprehensive Guide PDF

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Bauer prelims 5/4/06 10:23 am Page i Lithium in Neuropsychiatry The Comprehensive Guide Bauer prelims 5/4/06 10:23 am Page ii Bauer prelims 5/4/06 10:23 am Page iii Lithium in Neuropsychiatry The Comprehensive Guide Editors Michael Bauer MD PhD Professor of Psychiatry, Charité University Medicine Berlin, Berlin, Germany Paul Grof MD PhD FRCP Director of the Mood Disorders Center of Ottawa and Professor of Psychiatry, University of Toronto, Canada Bruno Müller-Oerlinghausen MD Professor Emeritus of Clinical Psychopharmacology, Freie Universität Berlin, Chairman of the Drug Commission of the German Medical Association, Germany CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2013 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Version Date: 20141208 International Standard Book Number-13: 978-0-203-00705-1 (eBook - PDF) This book contains information obtained from authentic and highly regarded sources. While all reasonable efforts have been made to publish reliable data and information, neither the author[s] nor the publisher can accept any legal responsibility or liability for any errors or omissions that may be made. The publishers wish to make clear that any views or opinions expressed in this book by individual editors, authors or contributors are personal to them and do not necessarily reflect the views/opinions of the publishers. The information or guid- ance contained in this book is intended for use by medical, scientific or health-care professionals and is provided strictly as a supplement to the medical or other professional’s own judgement, their knowledge of the patient’s medical history, relevant manufacturer’s instruc- tions and the appropriate best practice guidelines. Because of the rapid advances in medical science, any information or advice on dosages, procedures or diagnoses should be independently verified. The reader is strongly urged to consult the relevant national drug formulary and the drug companies’ printed instructions, and their websites, before administering any of the drugs recommended in this book. This book does not indicate whether a particular treatment is appropriate or suitable for a particular individual. Ultimately it is the sole responsibility of the medical professional to make his or her own professional judgements, so as to advise and treat patients appropriately. The authors and publishers have also attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowledged please write and let us know so we may rectify in any future reprint. Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, please access www.copyright.com (http://www.copyright. com/) or contact the Copyright Clearance Center, Inc. (CCC), 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400. CCC is a not-for- profit organization that provides licenses and registration for a variety of users. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe. Visit the Taylor & Francis Web site at http://www.taylorandfrancis.com and the CRC Press Web site at http://www.crcpress.com Bauer prelims 5/4/06 10:23 am Page v Contents Dedication to Professor Schou viii List of contributors ix Foreword by Kay Redfield Jamison xvii Preface by the editors xix A. INTRODUCTION AND HISTORY 1. Lithium: a fascinating element in neuropsychiatry 3 Philip H Cogen, Peter C Whybrow 2. History of lithium treatment 9 Mogens Schou, Paul Grof 3. The lithium story: a journey from obscurity to popular use in North America 17 Samuel Gershon, Chad Daversa 4. Different views on the use of lithium across continents 25 Daniel Z Lieberman, Jaclyn Saggese, Frederick K Goodwin 5. The position of lithium in international and national guidelines for the treatment 33 of mood disorders Nicolas Andres Crossley, Bruno Müller-Oerlinghausen, Tasha Glenn, Michael Bauer 6. Facing two demons: lithium therapy from a patient’s point of view 43 Marylou Selo B. CLINICAL APPLICATIONS Mood and related disorders 7. Lithium in the treatment of acute mania 59 Rasmus W Licht 8. Maintenance treatment with lithium in bipolar disorder 73 John R Geddes, Guy M Goodwin 9. Effectiveness of lithium in naturalistic settings 87 Mario Maj v Bauer prelims 5/4/06 10:23 am Page vi vi Lithium in Neuropsychiatry: The Comprehensive Guide 10. Lithium maintenance of unipolar depression 99 John M Davis 11. The acute antidepressive effects of lithium: from monotherapy to augmentation 109 therapy in major depression Michael Bauer, Nicolas Andres Crossley, Sonja Gerber, Tom Bschor 12. Lithium in schizoaffective disorder and schizophrenia 129 Christopher Baethge, Christian Simhandl 13. Lithium in rapid cycling bipolar disorder 145 David J Muzina, Michael Bauer, Joseph R Calabrese 14. Responders to long-term lithium treatment 157 Paul Grof 15. The suicide-preventive and mortality-reducing effect of lithium 179 Bruno Müller-Oerlinghausen, Bernd Ahrens, Werner Felber Special populations and applications in medicine 16. Lithium treatment in children and adolescents: a selected review and 193 integration of research findings Anne Duffy 17. Lithium in the elderly 207 Laszlo Gyulai, Robert C Young, Johanna Sasse 18. Women and lithium treatment 217 Bettina Schmitz, Christof Schaefer, Andrea Pfennig 19. Therapeutic and prophylactic effects of lithium on pathological aggression 227 Jeffrey Bierbrauer, Agneta Nilsson, Bruno Müller-Oerlinghausen, Michael Bauer 20. The use of lithium in non-psychiatric conditions 237 Tom Bschor, Ute Lewitzka, Mazda Adli Effects on body systems 21. Lithium and the kidneys 251 Mogens Schou, Dieter Kampf 22. Effect of lithium on the thyroid and endocrine glands 259 John H Lazarus, George Kirov, Brian B Harris 23. Adverse neurological and neurotoxic effects of lithium therapy 271 Oliver Pogarell, Malte Folkerts, Ulrich Hegerl 24. Gastrointestinal, metabolic and body-weight changes during treatment with lithium 283 Janusz K Rybakowski, Aleksandra Suwalska 25. Lithium and its cardiovascular effects 295 Jeffrey Bierbrauer, Jochen Albrecht, Bruno Müller-Oerlinghausen 26. Dermatologic effects of lithium: adverse reactions and potential therapeutic utility 303 Andrea Pfennig, Dorian Deshauer, Gisela Albrecht Bauer prelims 5/4/06 10:23 am Page vii Contents vii C. PHARMACOLOGY AND MECHANISMS 27. Lithium: its chemistry, distribution and transport in the body 311 Nick J Birch 28. Pharmacokinetics of lithium 321 Martin Alda 29. Interaction of lithium with neurotransmitter systems: serotonin and others 329 Georg Juckel, Paraskevi Mavrogiorgou 30. Lithium and cellular signal transduction pathways 341 Dietrich van Calker 31. Effects of lithium on gene expression 365 Jun-Feng Wang, L Trevor Young 32. Potential use of lithium in neurodegenerative disorders 381 De-Maw Chuang, Josef Priller 33. The effects of lithium on the immune system 399 Mohammed S Inayat, Vincent S Gallicchio 34. Lithium in neuropsychiatry: results from brain imaging studies 415 E Serap Monkul, Jair C Soares 35. Genetic factors and response to lithium treatment 423 Martin Alda, Paul Grof, Petr Zvolsky 36. Effects of lithium on behavior and cognition in animals and healthy humans 433 Robert H Belmaker, Alona Shaldubina, Yuly Bersudsky D. PRACTICAL ISSUES 37. Recommendations for the safe use of lithium 443 Anne Berghöfer, Paul Grof, Bruno Müller-Oerlinghausen 38. Latency, discontinuation and re-use of lithium treatment 465 Ross J Baldessarini, Leonardo Tondo, Gianni L Faedda, Adele C Viguera, Christopher Baethge, Paola Salvatore, Irene M Bratti, John Hennen 39. Compliance with long-term lithium treatment 483 Per Vestergaard, Krista Nielsen Straarup, Kenneth Thau 40. Lithium intoxication: signs and treatment 491 Frank Martens 41. The Lithium Information Center 501 James W Jefferson, John H Greist, Margaret G Baudhuin, Bette L Hartley, David J Katzelnick 42. Economics of lithium prophylaxis in bipolar disorders 505 Anne Berghöfer Index 513 Bauer prelims 5/4/06 10:23 am Page viii Dedication Prof Dr Dr hon MOGENS SCHOU (1918–2005) This book is dedicated to MOGENS SCHOU who taught all of us how to use lithium in neuropsychiatry. Once he discovered lithium’s prophylactic action in mood disorders, he researched tirelessly all its aspects and did not spare any effort to make the treatment available to all those in need, the millions of patients with recurrent mood disorders. viii Bauer prelims 5/4/06 10:23 am Page ix Contributors Editors Contributors Michael Bauer, MD PhD Mazda Adli, MD Professor of Psychiatry Supervising Psychiatrist Department of Psychiatry and Psychotherapy Department of Psychiatry and Psychotherapy Charité University Medicine Berlin Charité University Medicine Berlin Campus Charité Mitte Campus Charité Mitte Berlin Berlin Germany Germany Paul Grof, MD, PhD, FRCP Bernd Ahrens, MD Director, Mood Disorders Center of Ottawa Privatdozent Ottawa, Ontario Arcus Institute for Disease Management Canada Office Luebeck and Luebeck Professor of Psychiatry Germany University of Toronto Toronto, Ontario Gisela Albrecht, MD Canada Vivantes Clinic Spandau Director, Clinic for Dermatology and Bruno Müller-Oerlinghausen, MD Allergology Professor Emeritus of Clinical Berlin Psychopharmacology Germany Freie Universität Berlin and Jochen Albrecht, MD Chairman, Drug Commission of the German Head, Medical Association Department of Psychiatry and Psychotherapy Berlin Charité University Medicine Berlin Germany St. Hedwig Krankenhaus Berlin Germany ix

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