Lipid-Soluble Antioxidants: Biochemistry and Clinical Applications

654 Pages·1992·13.81 MB·English

by  L. Packer (auth.)

MCBU
Molecular and Cell Biology Updates
Series Editors:
Prof. Dr. Angelo Azzi
Institut fOr Biochemie
und Molekularbiologie
BOhlstr. 28
CH-3012 Bern
Switzerland
Prof. Dr. Lester Packer
Dept. of Molecular
and Cell Biology
251 Life Science Addition
Membrane Bioenergetics Group
Berkeley, California 94720
USA
Lipid-Soluble Antioxidants:
Biochemistry and Clinical
Applications
Edited by A.S.H. Ong
L. Packer
Birkhauser Verlag
Basel' Boston' Berlin
Volume Editors' addresses:
Dr. A.5.H. Ong Prof. Dr. L. Packer
Malaysian Palm Oil Promotion Dept. of Molecular and Cell Biology
Council 251 Life Science Addition
Bangunan Getah Asli Membrane Bioenergetics Group
148 Jalan Ampang Berkeley, California 94720
50450 Kuala Lumpur USA
Malaysia
Library of Congress Cataloging-in-Publication Data
A CIP catalogue record for this book is available from the Library of Congress, Washington D.C., USA
Deutsche Bibliothek Cataloging-in-Publication Data
Upid-soluble antioxidants: biochemistry and clinical
applications / ed. by A.S.H. Ong; L. Packer. -Basel; Boston; Berlin:
Birkhauser, 1992
(Molecular and cell biology updates)
ISBN 978-3-0348-7434-2 ISBN 978-3-0348-7432-8 (eBook)
DOll 0.1 007/978-3-0348-7432-8
NE: Ong, Augustine S. H. IHrsg.J
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© 1992 Birkhauser Verlag
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TABLE OF CONTENTS
Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XI-XII
VITAMIN E: TOCOPHEROLS AND TOCOTRIENOLS AND UBIQUINONES
New horizons in vitamin E research - The vitamin E cycle, biochemistry, and
clinical applications .............................. . 1
L. Packer
The reactivity of tocotrienols and other lipid-soluble antioxidants towards
peroxyl radicals ............................... . 17
C. Suarna, R.T Dean and R. Stocker
Physical/chemical studies of vitamin E in membranes 27
C. Covil, R.S. Phadke and S. Srivastava
Synergistic effect of lipid hydroperoxyl radical scavenging and lipid
hydroperoxide reduction in the inhibition of lipid peroxidation in
biomembranes ............................ . 47
M. Maiorino and F. Ursini
Determination of rate constants for antioxidant activity and use of the crocin
assay ...................................... . 52
W Bors, C. Michel and M. Saran
Vitamin E in protection of oxidative impairment in endothelial and platelet
functions ................................... . 65
I. Tomita, Y. Zhou, M. Ezaki, T Onda and T Tomita
Antioxidant effectiveness of tocopherol isomers .. 76
C.C. Duthie, D.B. McPhail, P.C. Morrice andJ.R. Arthur
Effect of vitamin E on metabolism of uremic low density lipoproteins in
human monocyte-derived macrophage ................. . 85
S. Yukawa, A. Hibino, T Maeda, H. Nomoto and I. Nishide
VI
Difference of antioxidative effect between vitamin E and selenium . 92
L.Z. Zhu, Y.P. He, l.H. Piao, Q.Y. Cai, C.P. Sun, l.zh. Chang, K Wu,
l.P. Cong
Tocopherol and tocotrienol plasma transport and tissue concentrations:
Implications for their relative biological functions . . . . . . . . . . . . 105
KC. Hayes, A. Pronczuk, l.S. Liang and S. Lindsey
Modulation of cell proliferation by tocopherols and tocotrienols: Role in
arteriosclerosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123
A. Azzi, D.O. Boscoboinik and E. Chatelain
Vitamin E and health in the marmoset monkey: A non-human primate model
for nutritional research . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 134
l.S. Charnock, T.M. Bridle, l. Turner, P.L. McLennan and
M.Y. Abeywardena
Antitumor and antioxidant activity of tocotrienols 152
K Komiyama, M. Hayashi, S. Cha and M. Yamaoka
Tocopherols, carotenoids and the glutathione system . 160
H. Sies, ME Murphy, P. OJ Mascio and W Stahl
Nutrition of tocotrienols and lipid metabolism . . . . . . . . . . 166
M. Sugano, I. Ikeda, K Imaizumi, K Koba, T. Okamoto, I. Niiya,
H. Watanabe, A.SH. Ong, D.T.S. Tan and A. Gapor
CAROTENOIDS, FLAVONOIDS AND RETINOIDS
Carotenoids and vitamin A: An overview 178
l.A. Olson
Metabolism of carotenoids by enzymes of oxygen metabolism 193
L.M. Canfield, l.G. Valenzuela andl.W Forage
Role of ~-carotene in disease prevention with special reference to cancer. 208
VN. Singh
Anti-tumor and anti-tumor promoting activity of (X- and ~-carotene . 228
H. Nishino, M. Murakoshi, H. Kitana, R. Iwasaki, Y. Tanaka, M. Tsushima,
T. Matsuno, H. Okabe, 1. Okuzumi, T. Hasegawa, 1. Takayasu, Y. Satomi,
H. Tokuda, A. Nishino and A. Iwashima
Production of palm oil carotenoid concentrate and its potential application in
nutrition ..................................... . 243
Y.M. Choo, S.c. Yap, C.K. Ooi, A.SH. Ong and S.H. Goh
VII
Carotenoids, novel polyene polyketones and new capsorubin isomers
as efficient quenchers of singlet molecular oxygen . . . . . . . . 255
T.P.A. Devasagayam, H. Ippendorf, T. Werner, H.-D. Martin and
H. Sies
Modification of alloxan diabetes in rats by vitamin A status 265
Y.M'/' Chung, P.M.M. Chiu and H.L. Wong
Flavonoids in foods: Their significance for nutrition and health 274
B. Stavric and T.I. Matula
Studies on flavonoids and related compounds as antioxidants in food . 295
N.P. Das and L. Ramanathan
Autocoid-immunopharmacology of flavonoids . . . . . . . . . . . . . 307
S.S. Gambhir, B.L. Pandey, K.S. Devi, R.S. Banerjee and G. Dasgupta
Anticarcinogenicity of flavonoids as studied by inhibition of lipid
peroxidation, microsomal degranulation and their interactions with
benzo(a)pyrene metabolites ..................... . 320
H.M. Dani, S. Sharma, Neelam and Harkirat
Role of retinoids in modulating the molecular actions of environmental
carcinogens . . 330
V.C. Goswami
PARASITIC AND INFECTIOUS DISEASES
Free radicals and antioxidants in malaria 337
N. H. Hunt, M. Kopp and R. Stocker
Oxygen free radicals in malaria . 355
S. Nakornchai and S. Anantavara
The mechanism of antimalarial action of artemisinin (Qinghaosu) 363
S. Kamchonwongpaisan, N. Vanitchareon and Y. Yuthavong
Erythrocytic GSH level and stability in Plasmodium vivax malaria 373
J. Bhattacharya
Plasma lipid peroxidation in P. Jalciparum malaria . 397
B.S. Das and D'/' Thurnham
Presence, formation and function of ubiquinones Q6 and Q8 in filarial
parasites ................................ . 406
R.K.Raj
VIII
Catalase activity in red cell and liver of mice infected with Plasmodium
berghei .................................. . 416
S. Areekul and Y. Boonme
CLINICAL APPLICATIONS. ANTIOXIDANT THERAPY
The hypolipidaemic effect of different diets 424
WP.T.l. Ralph and A. Ralph
Epidemiological correlations between poor plasma levels of essential
antioxidants and the risk of coronary heart disease and cancer . 442
K.F. Gey
Effect of different antioxidants in experimental myocardial infarction 457
v.P. Menon, S. Sushma Kumari, A. layadeep, 1.S. Suresh Kumar,
S. Mathew and P.A. Kurup
Lipid-soluble plant phenols as antioxidants and anti-mutagens 469
T. Osawa
Anti-cancer effects of cis-unsaturated fatty acids both in vitro and
in vivo . 482
UN. Das
Clinical studies on polyunsaturated fatty acids and antioxidants in African
children ................................. . 507
M. Leichsenring, H.J. Bremer, HM. Ahmed, M.D. Laryea, A.B. Bello,
1. Lombeck and E. Mayatepek
Dihydrolipoic acid is protective against reperfusion injury. 515
Hl. Freisleben, F. Beyersdorf, H Assadnazari, Seewald, 1. Simon,
A. Hanselmann and G. Zimer
Effect of japanese herbal medicine, Sho-saiko-to-go-keishi-kashakuyaku-to
(TJ-960) on aging .............................. . 535
M. Hiramatsu, R. Edamatsu, H Ohyama and A. Mori
Lipoprotein oxidation .. 553
l.e. Fruchart and G. Luc
Hepatic lipid peroxidation in ethanol potentiated aflatoxin BJ hepatotoxicity . 567
C. Toskulkao and T. Glinsukon
Palm oil vitamin E effects in hypercholesterolemia. . . . . . . . . . . . . . 575
F. Atroshi, E. Antila, S. Sankari, 1. Treuthardt, A. Gapor, H Saloniemi and
T. Westermarck
IX
Fat soluble antioxidant vitamins in cancer patients . . . . . . . . 582
R. Singkamani, M. Suttajit, T. Chiewchanwit and D.I. Thurnham
Butylated hydroxy toluene toxicity. 590
R. Kahl
Effects of tocotrienols-rich vitamin E on patients with peripheral vascular
disease ................................... . 606
M.K. Teoh, M.K. Chong, M. famaludin
Protection from air pollution injury by dietary vitamin E 622
N.M. Elsayed
Subject Index .. 632