Leslie Sharkey DVM, PhD, DACVP • University of Minnesota CHALLENGING ANEMIA CASES 有 PDF
Preview Leslie Sharkey DVM, PhD, DACVP • University of Minnesota CHALLENGING ANEMIA CASES 有
CHALLENGING • Leslie Sharkey DVM, PhD, DACVP ANEMIA CASES • University of Minnesota 有挑战性的贫血案 例 • Regenerative 再生 – Hemorrhage 出血 • Blood loss 失血 CLASSIFICATION OF • Low protein 低蛋白 ANEMIA 贫血症的分类 – Hemolysis 溶血 • Red cell morphology红细胞形态 • Bilirubinuria/hyperbilirubinemia 胆红尿素/高胆红素血症 • Non-regenerative 非再生 – Anemia of inflammation炎症性贫血 – Renal disease肾脏疾病 – Bone marrow suppression骨髓抑制 • Toxicity毒性 • Neoplasia 瘤 • Immune-mediated 免疫介导 • Infectious (mostly viral)感染（多 为病毒感染） Case examples with blood film review 血涂片案例回顾 Case 1 • 5Y FS DSH • Presented for evaluation of progressive lethargy (past few weeks) and increased respiratory rate (last couple of days).过去数周里显示出嗜睡，过去几天里呼吸 频率增加 • Diagnosed with FeLV at 1Y 在1岁时诊断出猫白血病 毒 • PE- Mildly increased heart and respiratory rates, pale gums, slightly dehydrated PE- 心脏和呼吸率轻度增加，牙龈苍白，略显脱水 Case 1- 5Y FS DSH Test Result Units Reference Range WBC 4 .38 x103/µL 1.83-16.27 RBC 1.53 L x106/µL 6.44-10.36 Hgb 3.0 L g/dL 9.8-16.8 HCT 8.8 L % 29.5-47 MCV 57.6 H fL 37.4-50.4 MCHC 33.6 g/dL 32.1-39.7 Retic # 0.045 x106/µL .004-.066 Platelets 34 L x103/µL 110-413 TPP 7.7 H g/dL 5.7-7.5 Case 1- 5Y FS DSH Test Result Units Reference Range WBC* 1.00 L x103/µL 1.83-16.27 Neutrophils segs 0.45 L x103/µL 1.2-13.2 Neutrophils bands 0.02 x103/µL 0-.16 Lymphocytes 0.32 x103/µL 0.2-9.4 Monocytes 0.14 x103/µL 0-.8 Eosinophils 0.01 x103/µL 0-1.9 nRBC 340 H # /100 WBC None HCT 8.8 L % 29.5-47 Platelets 34 L x103/µL 110-413 *Corrected for the presence of nRBC. •Corrected WBC = Measured WBC x (100/(100 + #nRBC per 100WBC)) Compare original white cell count from the machine with the correct one based on the manual differential A Overview B C D 低红细胞密度，大小不均，1有核红细胞，新月体表示蛋白质含量高
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