Table Of Content

KIDNEY INTERNATIONAL Volume 43, Number 1, January 1993 Official Journal of the International Society of Nephrology Le Journal Official de la Société Internationale de Néphrologie Table of contents SYMPOSIUM ON CELL AND MOLECULAR BIOLOGY OF BASEMENT MEMBRANES IN HEALTH AND DISEASE Forefronts in Nephrology Arlie, Virginia, USA September 20-22, 1991 Introduction. Nicholas A. Kefalides, Lance A. Liotta, and Eric G. Neilson MOLECULAR INTERACTIONS—CELL RECEPTORS Laminin variants: Why, where and when? Eva Engvall Nidogen mediates the formation of ternary complexes of basement membrane components. Monique Aumailley, Cristina Battaglia, Ulrike Mayer, Dieter Reinhardt, Roswitha Nischt, Rupert Timpl, and Jay W. Fox Biological functions of entactin. Albert E. Chung, Li-Jin Dong, Chuanyue Wu, and Marian E. Durkin Role of laminin in endothelial cell recognition and differentiation. H. William Schnaper, Hynada K. Kleinman, and Derrick S. Grant Adhesion and activation of human neutrophils on basement membrane molecules. Jacques P. Borel, Georges Bellon, Roselyne Garnotel, and J.C. Monboisse Interaction between the 67 kilodalton metastasis-associated laminin receptor and laminin. Vittoria Cioce, Inger M.K. Margulies, Mark E. Sobel, and Vincent Castronovo MOLECULAR BIOLOGY AND REGULATION OF GENE EXPRESSION Molecular genetics of Alport syndrome. Karl Tryggvason, Jing Zhou, Sirkka Liisa Hostikka, and Thomas B. Shows Differential expression of type I collagen and cellular fibronectin isoforms in endothelial cell variants. Jeanne C. Myers Perlecan, the large low-density proteoglycan of basement membranes: Structure and variant forms. Douglas M. Noonan and John R. Hassell DEVELOPMENT AND GROWTH REGULATION Endothelial integrins and their role in maintaining the integrity of the vessel wall. Elisabetta Dejana, Marco Raiteri, Massimo Resnati, and Maria Grazia Lampugnani Role of laminin carbohydrates on cellular interactions. Marvin L. Tanzer, Subramanian Chan- drasekaran, John W. Dean III, and Martin S. Giniger Laminin distribution in developing glomerular basement membranes. Dale R. Abrahamson and Patricia L. St. John Basement membrane proteoglycans and development. John R. Couchman, Dale R. Abrahamson, and Kevin J. McCarthy BASEMENT MEMBRANES IN DISEASE Heterogeneity of antibodies in Goodpasture syndrome reacting with type IV collagen. Nicholas A. Kefalides, Nobuko Ohno, and Curtis B. Wilson Contents continued on next page Contents continued Identification of antigenic epitopes in type IV collagen by use of synthetic peptides. Nicholas A. Kefalides, Nobuko Ohno, Curtis B. Wilson, Howard Fillit, John Zabriski, and Joel Rosenbloom. 94 Polycystic kidney disease: Primary extracellular matrix abnormality or defective cellular differentiation? James P. Calvet 101 The glomerular mesangium in diabetes mellitus. Jeffrey I. Kreisberg and Suzanne H. Ayo 109 Renal tubular basement membrane and collagen type IV in diabetes mellitus. Fuad N. Ziyadeh . 114 Expression of type I collagen mRNA in glomeruli of rats with passive Heymann nephritis. Andrew W. Minto, Mitchell A. Fogel, Yasuhiro Natori, Yvonne M. O’Meara, Dale R. Abrahamson, Barbara Smith, and David J. Salant Immune modulation of biologic systems in renal somatic cells. Jerry Yee and Eric G. Neilson... Molecular characteristics of the Goodpasture autoantigen. Billy G. Hudson, Raghuram Kalluri, Sripad Gunwar, Milton E. Noelken, Mariko Mariyama, and Stephen T. Reeders Role of a basement membrane glycoprotein in anti-tubular basement membrane nephritis. Gretchen S. Crary, Avi Katz, Alfred J. Fish, Alfred F. Michael, and Ralph J. Butkowski Basement membrane biosynthesis as a target for developing inhibitors of angiogenesis with anti-tumor properties. Michael E. Maragoudakis, Eleftheria Missirlis, George D. Karakiulakis, Mariana Sarmonica, Maria Bastakis, and Nikos Tsopanoglou Cytoskeletal agents inhibit motility and adherence of human tumor cells. Mary L. Stracke, Mehrdad Soroush, Lance A. Liotta, and Elliott Schiffmann Human 92 kDa type IV collagenase: Functional analysis of fibronectin and carboxyl-end domains. Alex Y. Strongin, Ivan E. Collier, Peter A. Krasnov, L. Teresa Genrich, Barry L. Marmer, and Gregory I. Goldberg Cellular activation of the 72 kDa type IV procollagenase/TIMP-2 complex. Peter D. Brown, David E. Kleiner, Edward J. Unsworth, and William G. Stetler-Stevenson HISTORICAL ARCHIVES Remembering Homer Smith. Robert W. Berliner LABORATORY INVESTIGATION Characterization of acid-base transport mechanisms in the kidney cell line RCCT-28A. Elsa Bello-Reuss, with the technical assistance of Leigh Cabell-Kluch and Yuzhen Pan Characterization of peanut-lectin (+) cells derived from the RCCT-28A cell line. Elsa Bello-Reuss, with the technical assistance of Leigh Cabell-Kluch and Pamela Tyler Response of genetic hypercalciuric rats to a low calcium diet. Mark Kim, Nelson E. Sessler, Vrishali Tembe, Murray J. Favus, and David A. Bushinsky Dopamine DA,-receptor activation inhibits noradrenaline release in human kidney slices. Lars C. Rump, Eckhard Schwertfeger, Martin J. Schuster, Ulrike Schaible, Alexander Frankenschmidt, and Peter J. Schollmeyer 197 Role of NO on pressure-natriuresis in Wistar-Kyoto and spontaneously hypertensive rats. Hideki Ikenaga, Hiromichi Suzuki, Naohito Ishii, Hajime Itoh, and Takao Saruta 205 CLINICAL INVESTIGATION Effect of insulin-plus-glucose infusion with or without epinephrine on fasting hyperkalemia. Michael Allon, Azita Takeshian, and Nancy Shanklin LDL stimulates mesangial fibronectin production and chemoattractant expression. Brad H. Rovin and Laura C. Tan Human peritoneal mesothelial cells synthesize interleukin-6: Induction by IL-18 and TNFa. Nicholas Topley, Achim Jérres, Werner Luttmann, Meryl M. Petersen, M. Janine Lang, Karl-Heinz Thierauch, Christian Miiller, GeraldA . Coles, Malcolm Davies, and John D. Williams 226 Contents continued on next page Contents continued NMR spectroscopy as a novel approach to the monitoring of renal transplant function. Peta J.D. Foxall, George J. Mellotte, Michael R. Bending, John C. Lindon, and Jeremy K. Nicholson.... 234 Nephron segment-specific inhibition on Na*/K*-ATPase activity by cyclosporin A. James A. Tumlin and Jeff M. Sands NEPHROLOGY FORUM Growth factors in glomerulonephritis. Hanna E. Abboud INTERNATIONAL SOCIETY OF NEPHROLOGY Meetings Awards and Grants Travel Award form; 1993 ISN Congress in Jerusalem Instructions for Authors on pages xxii-xxiv KIDNEY INTERNATIONAL Volume 43, Supplement 39 Molecular Approaches to Nephrology: Prospects in Diagnosis and Management Bari, Italy March 19-22, 1992 Official Journal of the International Society of Nephrology Le Journal Official de la Société Internationale de Néphrologie Table of contents Introduction. F. Paolo Schena, Steven N. Emancipator, and J. Stewart Cameron IMMUNOGENETIC STUDIES Immunogenetic findings in glomerulonephritis. Michael H. Rambausek, Riidiger Waldherr, and Eberhard Ritz MHC gene polymorphism in primary IgA nephropathy. Richard Moore Molecular mapping of the HLA class II region in HLA-DR3 associated idiopathic membranous nephropathy. Steven H. Sacks, Catherine Warner, R. Duncan Campbell, and Ian Dunham ... Positional cloning approach to the dominant polycystic kidney disease gene, PKD1. Gregory G. Germino, Stefan Somlo, Debra Weinstat-Saslow, and Stephen T. Reeders CYTOKINES AND GLOMERULAR CELLS Cytokines and mesangial cells. R. Bernd Sterzel, Eckhard Schulze-Lohoff, and Martin Marx .. Effect of cytokines on the cytoskeleton of resident glomerular cells. Giovanni Camussi, Filippo Mariano, Luigi Biancone, Giuseppe Montrucchio, and Antonio Vercellone. ................. Modulation of renal production of C3 by proinflammatory cytokines. Vincenzo Montinaro, Mariella Di Cillo, Sabrina Perissutti, Leonardo Serra, Francesco Tedesco, Abdalla Rifai, and Francesco Paolo Schena Cytokine mRNA expression by cultured rat mesangial cells after contact with environmental lectins. Alessandro Amore, Federica Cavallo, Elena Bocchietto, Federico Bussolino, Bruno Gianoglio, Licia Peruzzi, Maria G. Porcellini, and Rosanna Coppo MATRIX EXPRESSION AND GLOMERULAR DISEASES Factors involved in the regulation of mesangial cell proliferation in vitro and in vivo. Jiirgen Floege, Eudora Eng, Bessie A. Young, and Richard J. Johnson Studies by competitive PCR of glomerulosclerosis in growth hormone transgenic mice. Emman- uel P. Peten, Liliane J. Striker, Arlyn Garcia-Perez, and Gary E. Striker CYTOKINES, GROWTH FACTORS AND GLOMERULAR DISEASE Role of tumor necrosis factor-a in the pathogenesis of glomerular diseases. Jestis Egido, Marta Goémez-Chiarri, Alberto Ortiz, Carmen Bustos, Javier Alonso, Carmen Gémez-Guerrero, Dul- cenombre Gomez-Garre, Maria José Lopez-Armada, Juanjo Plaza, and Eva Gonzalez Cytokines, mesangial cell activation and glomerular injury. John R. Sedor, Martha Koniecz- kowski, Shaoming Huang, Joseph H. Gronich, Yuichi Nakazato, Gideon Gordon, and Charles Role of interleukin-6 in the progression of mesangial proliferative glomerulonephritis. Yasuhiro Horii, Masayuki Iwano, Eiji Hirata, Hideo Shiiki, Yoshihiro Fujii, Kazuhiro Dohi, and Hyoe Ishikawa Contents continued Role of endothelin in glomerular injury. Norberto Perico and Giuseppe Remuzzi The intercrine superfamily and renal disease. Marta Gémez-Chiarri, Alberto Ortiz, Daniel Serén, Eva Gonzalez, and Jestis Egido ’ . : — Contents continued on next page Platelet-derived growth factor and proliferative glomerulonephritis. Loreto Gesualdo, Elena Ranieri, Giovanni Pannarale, Salvatore Di Paolo, and Francesco Paolo Schena Glomerulosclerosis in mice transgenic for native or mutated bovine growth hormone gene. Chih-Wei Yang, Liliane J. Striker, John J. Kopchick, Wen Y. Chen, Carlo M. Pesce, Emmanuel P. Peten, and Gary E. Striker Expression of 5-lipoxygenase and 5-lipoxygenase activation protein in glomerulonephritis. Abdalla Rifai, Hideto Sakai, and Mitsunori Yagame MOLECULAR ASPECTS OF TUBULO INTERSTITIAL INJURY Angiotensin II as a hypertrophogenic cytokine for proximal tubular cells. Gunter Wolf and Eric G. Neilson Renal tubular epithelial and T cell interactions in autoimmune renal disease. Vicki Rubin Kelly, Cristina Diaz-Gallo, Anthony M. Jevnikar, and Gary G. Singer Gene transfer into the mammalian kidney: First steps towards renal gene therapy. Adrian S. Woolf, Ricardo J. Bosch, and Leon G. Fine MOLECULAR ASPECTS OF RENAL TRANSPLANTATION Prospects for anti-rejection therapies based upon CD8-dependent immunoregulation. Mark L. Tykocinski and David R. Kaplan Interaction between T lymphocytes and kidney epithelial cells during renal allograft rejection. John A. Kirby, Magaral R. Rajasekar, Yvan Lin, George Proud, and R.M.R. Taylor Differential in situ expression of cytokine genes in human renal transplantation. Michael G. Tovey, Anne Deglise-Favre, and Damien Schoevaert Analysis of T cell lines from rejecting renal allografts. Benito A. Yard, Mariska Kooymans- Couthino, Thomas Reterink, Peter van den Elsen, Marion E. Paape, Jan Antony Bruyn, Leendert A. van Es, Mohammed R. Daha, and Fokko J. van der Woude MOLECULAR ASPECTS OF HEMODIALYSIS Induction of interleukin-1 during hemodialysis. Nicole Haeffner-Cavaillon, Gerlinde Jahns, Jean-Louis Poignet, and Michel D. Kazatchkine Induction of mRNA for tumor necrosis factor a in hemodialysis. Dario Roccatello, Sandra D’A lfonso, Daniela Peruccio, Giacomo Quattrocchio, Guido Cavalli, Ciro Isidoro, Giuseppe Piccoli, and Patricia Momigliano Richiardi Influence of hemodialysis on interleukin 6 production and gene expression by peripheral blood mononuclear cells. Giovanni Pertosa, Loreto Gesualdo, Emilia A. Tarantino, Elena Ranieri, Davide Bottalico, and Francesco P. Schena Role of platelet activating factor in hemodialysis. Ciro Tetta, Salvatore David, Luigi Biancone, Francesco Canino, Vincenzo Cambi, and Giovanni Camussi Instructions for Authors on page iv KIDNEY INTERNATIONAL Volume 43, Number 2, February 1993 Official Journal of the International Society of Nephrology Le Journal Official de la Société Internationale de Néphrologie Table of contents EDITORIAL REVIEW Endopeptidase-24.11 and its inhibitors: Potential therapeutic agents for edematous disorders and hypertension. Martin R. Wilkins, Robert J. Unwin, and A. John Kenny LABORATORY INVESTIGATION PDGF-receptor localizes to mesangial, parietal epithelial, and interstitial cells in human and primate kidneys. Charles E. Alpers, Ronald A. Seifert, Kelly L. Hudkins, Richard J. Johnson, and Daniel F. Bowen-Pope Effect of protein kinase C activation and down-regulation on active calcium transport. René J.M. Bindels, Jacqueline A. Dempster, Peter L.M. Ramakers, Peter H.G.M. Willems, and Carel H. van SD ah Ab cuieds sade etGeanods ected baeanedtecasbaba choles bbs 6 ekenereeeKeeneneaneeerheks Prostaglandin synthesis inhibition stimulates lithium reabsorption in the Henle’s loop in rats. Walter H. Boer, René Fransen, Peter Boer, Remmert de Roos, and Hein A. Koomans Extra-natriuretic effects of atrial peptide in humans. Luca De Nicola, Giulio Romano, Bruno Memoli, Bruno Cianciaruso, Massimo Sabbatini, Domenico Russo, Alfredo Caglioti, Giorgio Fuiano, Antonio Dal Canton, and Giuseppe Conte Visualization of serotonin effects on renal vessels of rats. Karlhans Endlich, Regina Kiihn, and Michael Steinhausen, with the technical assistance of Rudolf Dussel Somatostatin antagonizes angiotensin II effects on mesangial cell contraction and glomerular filtration. Carmen Garcia-Escribano, Maria Luisa Diez-Marqués, Mercedes Gonzdles-Rubio, Manuel Rodrigues-Puyol, and Diego Rodriguez-Puyol Renal basement membranes by ultrahigh resolution scanning electron microscopy. Kazue Hiron- aka, Hirofumi Makino, Yasushi Yamasaki, and Zensuke Ota Effects of angiotensin II receptor blockade on remnant glomerular permselectivity. Gert Mayer, Richard A. Lafayette, James Oliver, William M. Deen, Bryan D. Myers, and Timothy W. Meyer . Renal endothelin gene expression is increased in remant kidney and correlates with disease progression. Silvia Orisio, Ariela Benigni, Isabella Bruzzi, Daniela Corna, Norberto Perico, Carla Zoja, Luca Benatti, and Giuseppe Remuzzi Fish oil has protective and therapeutic effects on proteinuria in passive Heymann nephritis. Wolfgang J. Weise, Yasuhiro Natori, Jerrold S. Levine, Yvonne M. O’Meara, Andrew W. Minto, Eric C. Manning, D. Jordi Goldstein, Dale R. Abrahamson, and David J. Salant CLINICAL INVESTIGATION Heparin suppresses mesangial cell proliferation and matrix expansion in experimental mesangio- proliferative glomerulonephritis. Jiirgen Floege, Eudora Eng, Bessie A. Young, William G. Couser, and Richard J. Johnson Structural-functional relationships in type I mesangiocapillary glomerulonephritis. Masuji Hattori, Youngki Kim, Michael W. Steffes, and S. Michael Mauer Effects of insulin-like growth factor I on renal function in normal men. Raimund Hirschberg, Giuliano Brunori, Joel D. Kopple, and Hans-Peter Guler Effects of kidney or kidney-pancreas transplantation on plasma pentosidine. Donald E. Hricik, James A. Schulak, David R. Sell, John F. Fogarty, and Vincent M. Monnier Contents continued on next page Contents continued Survival analysis of dialysis patients in Okinawa, Japan (1971-1990). Kunitoshi Iseki, Nobuyuki Kawazoe, Akira Osawa, and Koshiro Fukiyama Lipoprotein heterogeneity in end-stage renal disease. Jorge Joven, Elizabet Vilella, Suhail Ahmad, Marian C. Cheung, and John D. Brunzell Converting-enzyme inhibitor versus calcium antagonist in cyclosporine-treated renal transplants. Georges Mourad, Jean Ribstein, and Albert Mimran Urinary excretion of platelet activating factor in patients with immune-mediated glomerulonephritis. Marina Noris, Ariela Benigni, Paola Boccardo, Eliana Gotti, Emilio Benfenati, Sistiana Aiello, Marta Todeschini, and Giuseppe Remuzzi Localization of apolipoprotein(a) and B-100 in various renal diseases. Hirokazu Sato, Satoru Suzuki, Mitsuhiro Ueno, Hisaki Shimada, Ryou Karasawa, Shin-Ichi Nishi, and Masaaki Arakawa The spectrum of bone disease in end-stage renal failure—An evolving disorder. Donald J. Sherrard, Gavril Hercz, York Pei, Norma A. Maloney, Celia Greenwood, Arif Manuel, Carl Saiphoo, Stanley S. Fenton, and Gino V. Segre Effects of dietary protein restriction on hemodynamics in chronic renal failure. Masayoshi Shichiri, Yasuhide Nishio, Mitsuo Ogura, Matsuhiko Suenaga, and Fumiaki Marumo Organic osmolytes in human and other mammalian kidneys. Peter C.B. Sizeland, Stephen T. Chambers, Michael Lever, Lois M. Bason, and Richard A. Robson Distribution ef GBM heparan sulfate proteoglycan core protein and side chains in human glomerular diseases. Jacob van den Born, Lambert P.W.J. van den Heuvel, Marinka A.H. Bakker, Jacques H. Veerkamp, Karel J.M. Assmann, Jan J. Weening, and Jo H.M. Berden TECHNICAL NOTE New technique to assess hypoxia-induced cell injury in individual isolated renal tubules. Andreas Kribben, Jack F.M. Wetzels, Eric D. Wieder, Thomas J. Burke, and Robert W. Schrier Permeable type I collagen membrane promotes glomerular epithelial cell growth in culture. Kazuo Nosaka, Tadahiro Nishi, Hiromi Imaki, Keiji Suzuki, Shoji Kuwata, Eisei Noiri, Chikara Aizawa, and Kiyoshi Kurokawa .. RAPID COMMUNICATIONS Suppression of experimental crescentic glomerulonephritis by the interleukin-1 receptor antagonist. Hui Y. Lan, David J. Nikolic-Paterson, Mario Zarama, James L. Vannice, and Robert C. COL4AS split site mutation and aS(IV) collagen mRNA in Alport syndrome. Kai-Olaf Netzer, Oliver Pullig, Ulrich Frei, Jing Zhou, Karl Tryggvason, Manfred Weber NEPHROLOGY FORUM Renovascular disease in children. Julie R. Ingelfinger INTERNATIONAL SOCIETY OF NEPHROLOGY Meetings Awards and Grants Special Subscription Offer for Fellows Travel Award form; 1993 ISN Congress in Jerusalem Instructions for Authors on page xviii KIDNEY INTERNATIONAL Volume 43, Supplement 40 “Options in Renal Therapy” Key Biscayne, Florida, USA December 5-7, 1992 Table of contents Introduction. Karl D. Nolph and Lee W. Henderson Morbidity and mortality of CAPD and hemodialysis. Rosario Maiorca, Giovanni C. Cancarini, Giulio Brunori, C. Camerini, and Luigi Manili Comparative morbidity among hemodialysis and continuous ambulatory peritoneal dialysis patients. David N. Churchill Quality of life in patients undergoing renal replacement therapy. Ram Gokal Urea kinetic and middle molecule approaches to assessing the adequacy of hemodialysis and CAPD. Prakash Keshaviah Nutrition and adequacy of dialysis. How do hemodialysis and CAPD compare? Jonas Bergstrém and Bengt Lindholm Dialysis therapy in the elderly patient. Allen R. Nissenson Dialysis considerations for diabetic patients. Ramesh Khanna Continuous peritoneal dialysis for children: A decade of worldwide growth and development. Steven R. Alexander and Masataka Honda Complications of peritoneal dialysis related to increased intraabdominal pressure. Joanne M. Access problems plague both peritoneal dialysis and hemodialysis. Karl D. Nolph Options in dialysis therapy: Significance of cardiovascular findings. Volker Wizemann, Mario Timio, Martin A. Alpert, and Wilfred Kramer Mineral metabolism and renal bone disease: Effects of CAPD versus hemodialysis. Jack W. Coburn Transplantation in peritoneal dialysis and hemodialysis. James F. Winchester, Carlos Rotellar, Mariella Goggins, Donna Robino, Mohammed R. Alijani, Thomas A. Rokowski, and William P. Residual renal function and recovery of renal function in patients treated by CAPD. Jacques Rottembourg Anemia and erythropoietin in hemodialysis and continuous ambulatory peritoneal dialysis. Stephen M. Korbet Non-medical factors that impact on ESRD modality selection. Allen R. Nissenson, Sarah S. Prichard, Ignatius K.P. Cheng, Ram Gokal, Minoru Kubota, Rosario Maiorca, Miguel C. Riella, Jacques Rottembourg, and John H. Stewart Instructions for Authors on page iv KIDNEY INTERNATIONAL Volume 43, Number 3, March 1993 Official Journal of the International Society of Nephrology Le Journal Official de la Société Internationale de Néphrologie Table of contents EDITORIAL REVIEW Pathophysiology of experimental nonoliguric acute renal failure. Nishio Honda and Akira Hishida LABORATORY INVESTIGATION Autosomal-dominant polycystic kidney disease in the rat. Benjamin D. Cowley, Jr., Seshagirirao Gudapaty, Amy L. Kraybill, Brian D. Barash, Michael A. Harding, James P. Calvet, and Vincent H. Gattone, Il Membrane currents controlled by physical forces in cultured mesangial cells. William Craelius, Margery J. Ross, Dennis R. Harris, Victor K. Chen, and Carlos E. Palant Soluble aggregates of IgG and immune complexes enhance IL-6 production by renal mesangial cells. Marieke E.A. van den Dobbelsteen, Fokko J. van der Woude, Willeke E.M. Schroeijers, Leendert A. van Es, and Mohamed R. Daha Parathyroid hormone raises cytosolic calcium in pancreatic islets: Study on mechanisms. George Z. Fadda, Prassert Thanakitcharu, Miroslaw Smogorzewski, and Shaul G. Massry Differential effects of 1,25-(OH),D, and 22-oxacalcitriol on phosphate and calcium metabolism. Jane L. Finch, Alex J. Brown, Noboru Kubodera, Yashuho Nishi, and Eduardo Slatopolsky ... Intra-GBM site of the functional filtration barrier for endogenous proteins in rats. Yoshihide Fujigaki, Mitsumasa Nagase, Shuzo Kobayasi, Sumi Hidaka, Masahiko Shimomura, and Akira Hishida Role of proteoglycans and cytoskeleton in the effects of TGF-81 on renal proximal tubule cells. H. David Humes, Takamichi Nakamura, Deborah A. Cieslinski, Diane Miller, Robert V. Emmons, and Wayne A. Border High glucose inhibits cytosolic calcium signaling in cultured rat mesangial cells. Paolo Mené, Giuseppe Pugliese, Flavia Pricci, Umberto Di Mario, Giulo A. Cinotti, and Francesco Pugliese . Binding of bacterial adhesins to rat glomerular mesangium in vivo. Aaro Miettinen, Benita Westerlund, Ann-Mari Tarkkanen, Tom Térnroth, Pdivi Ljungberg, Olli-Veikko Renkonen, and Timo K. Korhonen Effect of angiotensin II and norepinephrine on early growth response genes in the rat kidney. Mark E. Rosenberg and Thomas H. Hostetter, with the technical assistance of Stefan Kren and David Chmielewski Reversible compensatory hypertrophy in rat kidneys: Morphometric characterization. Melvin M. Schwartz, Monique Churchill, Anil Bidani, and Paul C. Churchill Effect of CsA on the expression of renin and angiotensin type | receptor genes in the rat kidney. Alda Tufro-McReddie, R. Ariel Gomez, Laura L. Norling, Alaaedin A. Omar, Leon C. Moore, and Frederick J. Kaskel 615 Susceptibility for infection-related glomerulopathy depends on non-MHC genes. Marie-Louise F. van Velthuysen, Aletta Veninga, Jan Anthonie Bruijn, Emile de Heer, and Gert Jan Fleuren ... 623 CLINICAL INVESTIGATION Calcium kinetics and the long-term effects of lowering dialysate calcium concentration. Angel Argilés, Peter G. Kerr, Bernard Canaud, Jean Louis Flavier, and Charles Mion Contents continued on next page Contents continued Immuno-effector characteristics of peritoneal cells during CAPD treatment: A longitudinal study. Michiel G.H. Betjes, Cornelis W. Tuk, Dirk G. Struijk, Raymond T. Krediet, Lambertus Arisz, Elisabeth C.M. Hoefsmit, and Rob H.J. Beelen > integrins are required for neutrophil degranulation induced by hemodialysis membranes. Alfred K. Cheung, Charles J. Parker, and Mary Hohnholt Renal interstitial expansion in insulin-dependent diabetes mellitus. Pascale H. Lane, Michael W. Steffes, Paola Fioretto, and §. Michael Mauer Baseline analysis of renal function in the Diabetes Control and Complications Trial. The Diabetes Control and Complications Trial Research Group, prepared by Mark E. Molitch, Michael W. Steffes, Patricia A. Cleary, and David M. Nathan Alpha-enolase: A novel cytosolic autoantigen in ANCA positive vasculitis. Fleur D.L. Moodie, Brian Leaker, Geraldine Cambridge, Nicholas F. Totty, and Anthony W. Segal In situ production of TNF-a, IL-8 and IL-2R in ANCA-positive glomerulonephritis. Jrene L. Noronha, Cornelia Kriiger, Konrad Andrassy, Eberhard Ritz, and Riidiger Waldherr PTH-induced osteoblast contraction is mediated by cysteine proteases. Khai K.-T. Tram, Samuel S. Murray, David B.N. Lee, and Elsa J.B. Murray Hyperparathyroidism, platelet intracellular free calcium and hypertension in chronic renal failure. Anthony E.G. Raine, Lindsey Bedford, Alec W.M. Simpson, Christopher C. Ashley, Richard Brown, J. Stuart Woodhead, and John G.G. Ledingham Calcium channel blockers protect transplant patients from cyclosporine-induced daily renal hypoperfusion. Piero Ruggenenti, Norberto Perico, Lidia Mosconi, Flavio Gaspari, Ariela Benigni, Carmen §. Amuchastegui, Isabella Bruzzi, and Giuseppe Remuzzi Gene expression of interleukin-18 during hemodialysis. Ralf Schindler, Silvia Linnenweber, Matthias Schulze, Martin Oppermann, Charles A. Dinarello, Stanley Shaldon, and Karl-Martin Mutations in the codon for a conserved arginine-1563 in the COL4AS5 collagen gene in Alport syndrome. Jing Zhou, Martin C. Gregory, Jens Michael Hertz, David F. Barker, Curtis Atkin, Edwin §. Spencer, and Karl Tryggvason RAPID COMMUNICATION Isolation and characterization of complement receptor type | from rat glomerular epithelial cells. Richard J. Quigg, Mitchel L. Galisoff, Arthur E. Sneed, Ill, and David Kim NEPHROLOGY FORUM Hepatorenal syndrome. Mortimer Levy ABSTRACT 33rd Congress of the Italian Society of Nephrology INTERNATIONAL SOCIETY OF NEPHROLOGY Meetings I: 3 ad Gitd nirn enna > stein edb os weed wa ee ace alii heed oud aan aaisaeaieaae aaa te 767 er re 6 occa en akeentibokeheeawhhhenaedeminskasebeeas s 768 Travel Award form; 1993 ISN Congress in Jerusalem Instructions for Authors on page xviii