IGF-Systemet som diagnostiskt hjälpmedel Kerstin Brismar Inst för molekylär medicin och kirurgi, Karolinska Institutet [email protected] 21 sept 2017 First publications IGF-I Kerstin Hall et al 1972 IGFBP-1 Kerstin Hall et al 1984 Why this difference? Gillian has too little IGF-I activity due to the diet which leads to premature aging in skin, bone, heart and brain Nigella has higher IGF activity due to her diet which increases the risk for cancer and T2DM IGF-I Insulin-like Growth Factor-I Effects Growth Metabolism Differentiation Antioxidant Cell survival Healing IGF-1 Markör för: Anabolism/katabolism Tillväxt GH-sekretion Nutritionsstatus Insulinsekretion IUGR (intrauterin tillväxthämning)
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