Journal of the American College of Cardiology 1999: Vol 34 Table of Contents

16 Pages·1999·6.4 MB·English

CONTENTS OF VOLUME 34
JULY 1999 VOLUME 34 NUMBER 1
LATE-BREAKING CLINICAL TRIALS MYOCARDIAL INFARCTION
Results From Late-Breaking Clinical Trials Sessions at 62 Survival 12 Years After Randomization to
ACCIS ’99 and ACC 99 Douglas C. Morris Streptokinase: The Influence of Thrombolysis in
Myocardial Infarction Flow at Three to Four Weeks
50TH ANNIVERSARY HISTORICAL John K. French, Thomas A. Hyde, Hitesh Patel, David J.
ARTICLE Amos, Stephanie C. McLaughlin, Bruce J. Webber,
Perfusion Imaging George A. Beller Harvey D. White
70 Long-Term (Three-Year) Prognosis of Patients
CLINICAL STUDIES
Treated With Reperfusion or Conservatively After
INTERVENTIONAL CARDIOLOGY Acute Myocardial Infarction Shmuel Gottlieb, Valentina
12 A Comparison of U.S. and Canadian Cardiac Boyko, David Harpaz, Hanoch Hod, Miriam Cohen, Lori
Catheterization Practices in Detecting Severe Coronary Mandelzweig, Zahi Khoury, Shlomo Stern, Solomon Behar,
Artery Disease After Myocardial Infarction: Efficiency, for the Israeh Thrombolytic Survey Group
Yield and Long-Term Implications Wayne B. Batchelor, 83 Effect of the Angiotensin-Converting Enzyme
Ert D. Peterson, Daniel B. Mark, J. David Knight, Inhibitor Transdolapril on Mortality and
Christopher B. Granger, Paul W. Armstrong, Morbidity in Diabetic Patients With Left Ventricular
Robert M. Califf Dysfunction After Acute Myocardial Infarction Ida
20 Editorial Comment Comparing the U.S. and Canadian Gustafsson, Christian Torp-Pedersen, Lars Kober, Finn
Approaches to Coronary Angiography: What Have We Gustafsson, Per Hildebrandt, on behalf of the Trace
Learned? John Z. Ayanian, Eugene Braunwald Study Group
23 Editorial Comment Catherization After Myocardial 90 Noninvasive Evaluation of Pulmonary Capillary Wedge
Infarction and the Mismeasure of Un-American Pressure in Patients With Acute Myocardial Infarction
Inactivity David A. Alter, C. David Naylor by Deceleration Time of Pulmonary Venous Flow
25 Laser Angioplasty of Restenosed Coronary Stents: Velocity in Diastole Atsushi Yamamuro, Kiyoshi Yoshida,
Results of a Multicenter Surveillance Trial Ra/f Késter, Takeshi Hozumt, Takashi Akasaka, Tsutomu Takagi,
Christian W. Hamm, Ricardo Seabra-Gomes, Gunhild Shuichirou Kajt, Takahiro Kawamoto, Junichi Yoshikawa
Herrmann, Horst Sievert, Carlos Macaya, Eckart Fleck,
Klaus Fischer, Johannes J. R. M. Bonnier, Jean Fajadet, ACUTE CORONARY SYNDROMES
Jiirgen Waigand, Karl-Heinz Kuck, Michel Henry, Marie 95 Risk Stratification of Emergency Department Patients
Claude Morice, Luciano Pizzulh, Michael M. Webb-Peploe, With Acute Coronary Syndromes Using P-Selectin
Arnd B. Buchwald, Lars Ekstrém, Eberhard Grube, Saad Al Judd E. Hollander, M. Ranu Muttreja, Margaret R.
Kasab, Antonio Colombo, Archimedes Sanati, Sjef M. P. G. Dalesandro, Frances S. Shofer
Ernst, Michael Haude, Martin B. Leon, Charles Ilsley,
106 Pravastatin Prevents Clinical Events in Revascularized
Rafael Beyar, Yvo Taeymans, Uwe Gladbach, Karl
Patients With Average Cholesterol Concentrations
Wegscheider, Patrick W. Serruys, for the Laser Angioplasty of
Greg C. Flaker, J. Wayne Warnica, Frank M. Sacks, Lemuel
Restenosed Stents (LARS) Investigators
A. Moyé, Barry R. Davis, Jean L. Rouleau, Richard R.
33 Mechanisms of Acute Lumen Gain and Recurrent
Webel, Marc A. Pfeffer, Eugene Braunwald, for the
Restenosis After Rotational Atherectomy of Diffuse
Cholesterol and Recurrent Events CARE Investigators
In-Stent Restenosis: A Quantitative Angiographic and
Intravascular Ultrasound Study Peter W. Radke,
CORONARY ARTERY DISEASE
Heinrich G. Klues, Philipp K. Haager, Rainer Hoffmann,
113 Effects of Medical Therapy on Outcome Assessment
Frank Kastrau, Thorsten Reffelmann, Uwe Janssens, Juergen
Using Exercise Thallium-201 Single Photon Emission
vom Dahl, Peter Hanrath
Computed Tomography Imaging: Evidence of a
40 Implications of Small Reference Vessel Diameter in
Protective Effect of Beta-Blocking Antianginal
Patients Undergoing Percutaneous Coronary
Medications Pierre Y. Marie, Nicolas Danchin, Fabrice
Revascularization Heribert Schunkert, Lari Harrell,
Branly, Michaél Angioi, Alain Grentzinger, Jean M. Virion,
Igor F. Palacios
Benoit Brouant, Pierre Olivier, Gilles Karcher, Yves Juilhere,
49 Is Redo Percutaneous Mitral Balloon Valvuloplasty Faiez Zannad, Alain Bertrand
(PMV) Indicated in Patients With Post-PMV Mitral
122 Contrast-Enhanced Transthoracic Second Harmonic
Restenosis? Asad Z. Pathan, Nasser A. Mahdi, Miltiadts
Echo Doppler With Adenosine: A Noninvasive, Rapid
N. Leon, Julio Lopez-Cuellar, Hector Simosa, Peter C. Block,
and Effective Method for Coronary Flow Reserve
Lari Harrell, Igor F. Palactos
Assessment Carlo Caiati, Norma Zedda, Cristiana
Montaldo, Roberta Montisci, Sabino Iliceto
CARDIAC SURGERY
55 Factors Correlating With Risk of Mortality After 131 Hormone Replacement Therapy in Postmenopausal
Transmyocardial Revascularization Danie/ Burkhoff, Women Protects Against Smoking-Induced Changes
Margaret N. Wesley, Jon R. Resar, Allan M. Lansing in Vascular Structure and Function Helena J. Teede,
Yu-Lu Liang, Louise M. Shiel, John J. McNeil, HEART TRANSPLANT
Barry P. McGrath 197 Volumetric Remodeling of the Proximal Left Coronary
Artery: Early Versus Late After Heart Transplantation
138 Editorial Comment Postmenopausal Hormone Therapy—
Klaus Pethig, Bernd Heublein, Rolf R. Meliss,
Good for Smokers? Deborah Grady
Axel Haverich
ENDOTHELIAL FUNCTION
ELECTROPHYSIOLOGY
140 Effect of Angiotensin-Converting Enzyme Inhibition 204 Shocks as Predictors of Survival in Patients With
and Angiotensin II Type 1 Receptor Antagonism on Implantable Cardioverter-Defibrillators Antonio
Postprandial Endothelial Function Hanneke W.
Pacifico, Laura L. Ferlic, Félix R. Cedillo-Salazar, Nadim
Wilmink, Jan D. Banga, Michel Hymering, Willem D.
Nasir, Jr, Timothy K. Doyle, Philip D. Henry
Erkelens, Erik S. G. Stroes, Ton J. Rabelink
146 Hyperglycemia Rapidly Suppresses Flow-Mediated PHYSIOLOGY
211 Noninvasive Assessment of the Cardiac Baroreflex:
Endothelium-Dependent Vasodilation of Brachial
Response to Downward Tilting and Comparison With
Artery Hiroaki Kawano, Takeshi Motoyama, Osamu
the Phenylephrine Method Naohiko Takahashi, Mikiko
Htrashima, Nobutaka Hirai, Yujt Miyao, Tomohiro
Sakamoto, Ktyotaka Kugiyama, Htsao Ogawa, Nakagawa, Tetsunori Satkawa, Tatsuhtko Oote, Tadafumi
Hirofum1 Yasue Akimitsu, Koji Kaneda, Masahide Hara, Tetsu Iwao,
Hidetoshi Yonemochi, Morio Ito, Toshtte Sakata
216 Effect of Acetylsalicylate on Cardiac and Muscular
HEART FAILURE
Pain Induced by Intracoronary and Intra-Arterial
155 Sustained Hemodynamic Effects of an Infusion of
Infusion of Bradykinin in Humans Achille Gaspardone,
Nesiritide (Human b-Type Natriuretic Peptide) in
Heart Failure: A Randomized, Double-Blind, Placebo- Filippo Crea, Fabrizio Tomat, Francesco Versaci, Antonio
Pellegrino, Luigi Chiartello, Pier A. Gioffré
Controlled Clinical Trial Roger M. Mills, Thierry H.
LeJemtel, Darlene P. Horton, Chang-seng Liang, Roberto
ADULT CONGENITAL HEART DISEASE
Lang, Marc A. Silver, Charles Lui, Kanu Chatterjee, on
223 Eisenmenger Syndrome in Adults: Ventricular Septal
Behalf of the Natrecor Study Group
Defect, Truncus Arteriosus, Univentricular Heart
163 Improvement of Left Ventricular Ejection Fraction,
Koichiro Niwa, Joseph K. Perloff, Samuel Kaplan, John S.
Heart Failure Symptoms and Prognosis After
Child, Pamela D. Miner
Revascularization in Patients With Chronic Coronary
Artery Disease and Viable Myocardium Detected by
PEDIATRIC CARDIOLOGY
Dobutamine Stress Echocardiography Jeroen J. Bax,
233 Clinical Features of Isolated Noncompaction of the
Don Poldermans, Abdou Elhendy, Jan H. Cornel, Eric
Ventricular Myocardium: Long-Term Clinical Course,
Boersma, Riccardo Rambaldi, Jos R. T: C. Roeland,
Hemodynamic Properties, and Genetic Background
Paolo M. Fioretti
Fuktko Ichida, Yujt Hamamichi, Toshio Miyawaki, Yasuo
170 Effect of Aspirin and Ifetroban on Skeletal Muscle Ono, Tetsuro Kamiya, Tetji Akagi, Hiromichi Hamada,
Blood Flow in Patients With Congestive Heart Failure Osamu Hirose, Takeshi Isobe, Katsuhiko Yamada, Shunji
Treated With Enalapril Stuart D. Katz, Michael Radin, Kurotobi, Hiroshi Mito, Toshiharu Miyake, Yasuo
Thomas Graves, Cynthia Hauck, Alan Block, Thierry H. Murakam1, Takeshi Nishi, Makoto Shinohara, Masashi
LeJemtel, for the Ifetroban Study Group Seguchi, Shinjiro Tashiro, Hirofumi Tomimatsu
241 Remote Telemedical Interpretation of Neonatal
CARDIOMYOPATHY Echocardiograms: Impact on Clinical Management in
177 Intravenous Immune Globulin in the Therapy of a Primary Care Setting Guy R. Randolph, Donald J.
Peripartum Cardiomyopathy Biykem Bozkurt, Flordeliza Hagler, Byjoy K. Khandheria, Eric R. Lunn, Walter J. Cook,
S. Villaneuva, Richard Holubkov, Tammy Tokarczyk, René James B. Seward, Patrick W. O'Leary
J. Alvarez, Jr.. Guy A. MacGowan, Srinivas Murah,
EXPERIMENTAL STUDY
Warren D. Rosenblum, Arthur M. Feldman,
246 Catheter-Based Myocardial Gene Transfer Utilizing
Dennis M. McNamara
Nonfluoroscopic Electromechanical Left Ventricular
181 Familial Dilated Cardiomypathy: Evidence for Genetic
Mapping Peter R. Vale, Douglas W. Losordo, Tengiz
and Phenotypic Heterogeneity Luisa Mestroni, Chiara
Tkebuchava, Donghui Chen, Charles E. Milliken,
Rocco, Dario Gregori, Gianfranco Sinagra, Andrea Di
Jeffrey M. Isner
Lenarda, Snjezana Mioctc, Matteo Vatta, Bruno Pinamonti,
255 Alterations in Cardiac Sarcoplasmic Reticulum Ca**
Francesco Muntoni, Alida L. P. Caforio, Wiliam J.
Regulatory Proteins in the Atrial Tissue of Patients
McKenna, Arturo Falaschi, Mauro Giacca, Fulvio Camerini,
With Chronic Atrial Fibrillation Tomoko Ohkusa,
and Heart Muscle Disease Study Group
Takeshi Ueyama, Jutaro Yamada, Masafumi Yano, Yoshihiko
Fujumura, Kensuke Esato, Masunort Matsuzaki
HYPERTROPHIC CARDIOMYOPATHY
191 Comparison of Dual-Chamber Pacing Versus Septal 264 Gender Differences in Molecular Remodeling in
Pressure Overload Hypertrophy Ev/en O. Weinberg,
Myectomy for the Treatment of Patients With
Hypertrophic Obstructive Cardiomyopathy: A Christiane D. Thienelt, Sarah E. Katz, Jozef Bartunek,
Minort Tajima, Susanne Rohrbach, Pamela S. Douglas,
Comparison of Objective Hemodynamic and Exercise
Beverly H. Lorell
End Points Steve R. Ommen, Rick A. Nishimura, Ray W.
Squires, Hartzell V. Schaff; Gordon K. Danielson, 274 Effects of Folate Supplementation in
A. Jamil Tajik Hyperhomocysteinemic Pigs Pierre Ambrosi,
Pierre H. Rolland, Heidi Bodard, André Barlatier, Philippe SPECIAL SECTIONS
Charpiot, Gwladys Guisgand, Alain Friggi, Odette
EDITOR’S PAGE
Ghiringhelli, Gilbert Habib, Gilles Bouvenot, Danielle
293 Annual Report—JACC 1998 William W. Parmley
Garton, Roger Luccioni
280 P-Selectin Inhibition Prevents Early Neutrophil
ACC News
Activation but Provides Only Modest Protection
294 President’s Page: The Great Circle: A Target for
Against Myocardial Injury in Dogs With Ischemia and
Forty-Eight Hours Reperfusion Masazumi Arai, Better Patient Care Arthur Garson, Jr.
Yoshthiro Masui, Pascal Goldschmidt-Clermont, Anthony
DiPaula, Cynthia Siu, Takeshi Kondo, Lewis C. Becker 296 ACC Committee Appointments
VIEWPOINT
310 LETTERS TO THE EDITOR
289 How Much to Lower Serum Cholesterol: Is It the
Wrong Question? C. Tissa Kappagoda, Ezra A.
Amsterdam 314 CORRECTION
AUGUST 1999 VOLUME 34 NUMBER 2
50TH ANNIVERSARY HISTORICAL Defibrillator: Analysis According to the Clinical
ARTICLE Presentation L/uis Mont, Mariana Valentino, Antonia
315 Valvular Heart Disease Robert O. Bonow Sambola, Martona Matas, Luis Aguinaga, Josep Brugada
358 Atrial Defibrillation With a Transvenous Lead: A
REVIEW ARTICLE Randomized Comparison of Active Can Shocking
318 Beta-Adrenergic Receptor Agonists and Cyclic Pathways Michael Cooklin, Mary R. Olsovsky, Randall G.
Nucleotide Phosphodiesterase Inhibitors: Shifting the Brockman, Stephen R. Shorofsky, Michael R. Gold
Focus from Inotropy to Cyclic Adenosine
Monophosphatase Matthew A. Movsesian
ELECTROPHYSIOLOGY
363 Transverse Conduction Capabilities of the Crista
CLINICAL STUDIES
Terminalis in Patients With Atrial Flutter and Atrial
Fibrillation Burghard Schumacher, Werner Jung,
ARRHYTHMIAS
325 Beta-Blocker Use and Survival in Patients With Harald Schmidt, Christoph Fischenbeck, Thorsten Lewalter,
Ventricular Fibrillation or Symptomatic Ventricular Andreas Hagendorff, Heyder Omran, Christian Wolpert,
Berndt Liideritz
Tachycardia: The Antiarrhythmics Versus Implantable
Defibrillators (AVID) Trial Derek V. Exner, James A.
374 Determinant of Microvolt-Level T-Wave Alternans in
Reiffel, Andrew E. Epstein, Robert Ledingham, Michael J.
Patients With Dilated Cardiomyopathy Kazumasa
Reiter, Qing Yao, Henry J. Duff; Dean Follmann, Eleanor
Adachi, Yoshio Ohnishi, Takasht Shima, Kouhet Yamashiro,
Schron, H. Leon Greene, Mark D. Carlson, Michael A.
Asumi Takei, Nami Tamura, Mitsuhiro Yokoyama
Brodsky, Toshio Akiyama, Christina Baessler, Jeffrey L.
Anderson, and the AVID Investigators 381 Characteristics of Electrograms Recorded at Reentry
Circuit Sites and Bystanders During Ventricular
334 Oral d,/ Sotalol Reduces the Incidence of Postoperative
Tachycardia After Myocardial Infarction Dusan Z.
Atrial Fibrillation in Coronary Artery Bypass Surgery
Kocovic, Tomoo Harada, Peter L. Friedman,
Patients: A Randomized, Double-Blind, Placebo-
William G. Stevenson
Controlled Study J. Anthony Gomes, John Ip, Francesco
Santoni-Rugiu, Davendra Mehta, Arisan Ergin, Steven 389 Value of the Electrocardiogram in Localizing the
Lansman, Elena Pe, Tert Takle Newhouse, Sally Chao Occlusion Site in the Left Anterior Descending
340 Editorial Comment Prevention of Postoperative Atrial Coronary Artery in Acute Anterior Myocardial
Fibrillation: What Is the Best Approach? Infarction Domien J. Engelen, Anton P. Gorgels, Emile C.
Philip J. Podrid Cheriex, Ebo D. De Muinck, Anton J. Oude Ophuis, Willem
R. Dassen, Jindra Vainer, Vincent G. van Ommen,
343 Intravenous Amiodarone for the Prevention of Atrial
Hein J. Wellens
Fibrillation After Open Heart Surgery: The
Amiodarone Reduction in Coronary Heart (ARCH) 396 Exaggerated QT Prolongation After Cardioversion of
Trial Thomas Guarnieri, Shellee Nolan, Sidney O. Gottlieb, Atrial Fibrillation Anna Maria J. Choy, Dawood Darbar,
Audrey Dudek, David R. Lowry Simonetta Dell Orto, Dan M. Roden
348 Editorial Comment Atrial Arrhythmias After Cardiac
402 Detection of Myocardial Injury During Transvenous
Surgery: Sisyphus Revisited? Peter R. Kowey Implantation of Automatic Cardioverter-Defibrillators
351 Arrhythmia Recurrence in Patients With a Healed Tanja M. Hurst, Michael Hinrichs, Christiane Breidenbach,
Myocardial Infarction Who Received an Implantable Norbert Katz, Bernd Waldecker
STRESS TESTING Heins, Yuriko Fischer, Hugo Stiegler, Ansgar Peters, Hans
409 Objective Evaluation of Regional Left Ventricular Reinauer, Frank C. Schoebel, Bodo E. Strauer,
Wall Motion During Dobutamine Stress Matthias Leschke
Echocardiographic Studies Using Segmental Analysis
of Color Kinesis Images Rick Koch, Roberto M. Lang, LEFT VENTRICULAR HYPERTROPHY
Maria-Jurema Garcia, Lynn Weinert, James Bednarz, 494 Angiotensinogen Gene M235T Polymorphism Predicts
Claudia Korcarz, Brendan Coughlan, Alan Spiegel, Eugene Left Ventricular Hypertrophy in Endurance Athletes
Kaji, Kirk T. Spencer, Victor Mor-Avi Jouko Karjalainen, Urho M. Kuala, Anu Stolt, Matti
420 Increased Stress Right Ventricular Activity on Dual Mantysaari, Matti Viutasalo, Katartina Kainulainen,
Isotope Perfusion SPECT: A Sign of Multivessel Kimmo Kontula
and/or Left Main Coronary Artery Disease Kim A.
Williams, Candace M. Schneider DIASTOLIC FUNCTION
500 Modulation of Left Ventricular Diastolic Distensibility
428 Coronary Doppler Intensity Changes During
by Collateral Flow Recruitment During Balloon
Handgrip: A New Method to Detect Coronary
Coronary Occlusion Hosam A. Remah, Hidetsugu Asanoi,
Vasomotor Tone in Coronary Artery Disease Paolo
Shuji Joho, Akihiko Igawa, Tomoki Kameyama, Takashi
Voci, Giovanni Testa, Gianluca Plaustro, Quintilio Caretta
Nozawa, Hiroshi Inoue
435 Prediction of Cardiac Events After Uncomplicated
Acute Myocardial Infarction by Clinical Variables and
ENDOTHELIAL FUNCTION
Dobutamine Stress Test Alessandro Salustri, Massimo
507 Glutathione Reverses Endothelial Dysfunction and
Ciavatti, Fulvia Seccareccia, Antonio Palamara
Improves Nitric Oxide Bioavailability 4/iram Prasad,
441 Comparison of Stress/Rest Myocardial Perfusion Neil P. Andrews, Feroz A. Padder, Mohsin Husain,
Tomography, Dipyridamole and Dobutamine Stress Arshed A. Quyyumt
Echocardiography for the Detection of Coronary
Disease in Hypertensive Patients With Chest Pain and NEW METHODS
Positive Exercise Test Gabriele Fragasso, Chunzeng Lu, 515 Combined Use of Pulsed and Color M-mode Doppler
Pawel Dabrowski, Paolo Pagnotta, Imad Shetban, Echocardiography for the Estimation of Pulmonary
Sergio L. Chierchia Capillary Wedge Pressure: An Empirical Approach
Based on an Analytical Relation Francisco Gonzalez-
MYOCARDIAL ISCHEMIA Vilchez, Miguel Ares, Jose Ayuela, Luis Alonso
448 A Comparison of Troponin T and Troponin I as 524 Double-Oblique Free-Breathing High Resolution
Predictors of Cardiac Events in Patients Undergoing
Three-Dimensional Coronary Magnetic Resonance
Chronic Dialysis at a Veterans Hospital: A Pilot Study
Angiography Matthias Stuber, René M. Botnar, Peter G.
Lynn Palacol Roppolo, Robert Fitzgerald, Jennifer Dillow,
Dantas, Daniel K. Sodickson, Kraig V. Kissinger, Marc Van
Thomas Ziegler, Mitchell Rice, Alan Maisel
Cauteren, Jan De Becker, Warren J. Manning
455 Elevated Endothelin Concentrations Are Associated
With Reduced Coronary Vasomotor Responses in
CORONARY SURGERY
Patients With Chest Pain and Normal Coronary 532 Effects of Coronary Artery Bypass Grafting Using
Arteriograms lan D. Cox, Hans E. Botker, Jens P. Internal Mammary Arteries for Diabetic Patients
Bagger, Helle S. Sonne, Bent @. Kristensen, Takasht Hirotani, Tadashi Kameda, Takayuki Kumamoto,
Juan Carlos Kaski Shogo Shirota, Mototugu Yamano
INTERVENTIONAL CARDIOLOGY PEDIATRIC CARDIAC SURGERY
461 Heparin After Percutaneous Intervention (HAPI): A 539 Is It Necessary to Routinely Fenestrate an Extracardiac
Prospective Multicenter Randomized Trial of Three
Fontan? LeNardo D. Thompson, Edwin Petrossian, Doff
Heparin Regimens After Successful Coronary
B. McElhinney, Natalia A. Abrikosova, Philip Moore,
Intervention Maher Rabah, Denise Mason, David W. M.
V. Mohan Reddy, Frank L. Hanley
Muller, Randal Hundley, Aaron D. Kugelmass, Bonnie
Weiner, Louis Cannon, Wiliam W. O'Neill,
PEDIATRIC CARDIOLOGY
Robert D. Safian 545 Factors Associated With Outcomes of Persistent
468 Retrieval and Analysis of Particulate Debris After Truncus Arteriosus Joyce M. Williams, Maaike de Leeuw,
Saphenous Vein Graft Intervention John G. Webb, Michael D. Black, Robert M. Freedom, William G.
Ronald G. Carere, Renu Virmani, Donald Baim, Paul S. Wilhams, Brian W. McCrindle
Teirstein, Patrick Whitlow, Colleen McQueen, Frank D.
554 The Hypoplastic Left Heart Syndrome With Intact
Kolodgie, Elizabeth Buller, Arthur Dodek, G. B. John
Atrial Septum: Atrial Morphology, Pulmonary Vascular
Mancini, Stephen Oesterle
Histopathology and Outcome Jack Rychik, Jonathan J.
476 Restenosis, Late Vessel Occlusion and Left Ventricular Rome, Margaret H. Collins, Wiliam M. DeCamph,
Function Six Months After Balloon Angioplasty in Thomas L. Spray
Diabetic Patients Eric Van Belle, Kaveh Abolmaali,
Christophe Bauters, Eugéne P. McFadden, EXPERIMENTAL STUDIES
Jean-Marc Lablanche, Michel E. Bertrand
561 External Beam Radiation After Stent Implantation
486 Changes of Hemostasis, Endogenous Fibrinolysis, Increases Neointimal Hyperplasia by Augmenting
Platelet Activation and Endothelins After Smooth Muscle Cell Proliferation and Extracellular
Percutaneous Transluminal Coronary Angioplasty in Matrix Accumulation Christoph Hehrlein, Simone Kaiser,
Patients With Stable Angina Markus Borries, Michael
Reimer Riessen, Jiirgen Metz, Peter Fritz, Wolfgang Kiibler
Editorial Comment Vascular Radiation Therapy: The Devil 594 Cardiomyocytes from Hearts With Left Ventricular
Is in the Dose Paul S. Teirstein Dysfunction After Ischemia-Reperfusion Do Not
570 Double Component Action Potentials in the Posterior Manifest Contractile Abnormalities Y. Chandrashekhar,
Approach to the Atrioventricular Node: Do They Arun J. Prahash, Soma Sen, Sudhir Gupta, Inder 8. Anand
Reflect Activation Delay in the Slow Pathway? Jacques 603 — Editorial Comment Cellular and Extracellular Mechanisms
M. T. de Bakker, Peter Loh, Méléze Hocini, Bernard Causing Myocardial Stunning Anthony J. Baker
Thibault, Michiel J. Janse
578 Flow Dynamics of QW7437, a New EDITOR’S PAGE
Dodecafluoropentane Ultrasound Contrast Agent, in 606 An Old Friend Turns 100 William W. Parmley
the Microcirculation: Microvascular Mechanisms for
Persistent Tissue Echo Enhancement Takanori Yasu,
Geert W. Schmid-Schénbein, Bruno Cotter, SPECIAL SECTIONS
Anthony N. DeMaria
Hehe : ACC News
587 hinges yt aba ona Mg te yas and o’ 607 = President’s Page: What Is Advocacy Doing for Us?
entricular Outflow Volume Determinations an >
Semiautomated Calculation of Shunt Volumes ee ee ee ene
Through Atrial Septal Defects by Digital Color
Doppler Flow Mapping in a Chronic Animal Model 610 LETTERS TO THE EDITOR
Takahiro Shiota, Michael Jones, Satoshi Aida, Masahide
Chikada, Hiroyuki Tsujino, Taher El-Kadi, David J. Sahn 613 CORRECTIONS
SEPTEMBER 1999 VOLUME 34 NUMBER 3
50TH ANNIVERSARY HISTORIAL Marmur, Subhash Kini, George Dangas, Thomas P. Cocke,
ARTICLE Sylvan Wallenstein, Eppie Brown, John A. Ambrose,
615 Percutaneous Transluminal Coronary Angioplasty Samin K. Sharma
Spencer B. King 672 Editorial Comment Elevation of Creatine Kinase, MB
Fraction After Elective Coronary Intervention: A Valid
VIEWPOINT Surrogate End Point of Poor Late Outcome?
618 Cause of Death in Clinical Research: Time for a Guy 5. Reeder
Reassessment? Michael S. Lauer, Eugene H. Blackstone, 674 Changing Outcomes in Percutaneous Coronary
James B. Young, Ertc J. Topol Interventions: A Study of 34,752 Procedures in
Northern New England, 1990 to 1997 Paul D.
REVIEW ARTICLES McGrath, David J. Malenka, David E. Wennberg, Samuel
621 Management of Ventricular Arrhythmias: A Trial- J. Shubrooks, ; William A. Bradley, John F. Robé, Mirle
based Approach Patrick J. Welch, Richard L. Page, A. Kellett, Jr., ThomasJ . Ryan, Jr., Michael J. Hearne,
Mohamed H. Hamdan Bruce Hettleman, John R. O'Meara, Peter VerLee, Matthew
631 Assessment and Treatment of Endothelial Dysfunction W. Wathens, Wentirop D. Paper, Gw eld T- O'Conner, ie
is Hheeaaes “Laid I dade the Northern New England Cardiovascular Disease Study
Group
CLINICAL STUDIES 681 Multivariate Prediction of In-Hospital Mortality After
Percutaneous Coronary Interventions in 1994-1996
INTERVENTIONAL CARDIOLOGY OS soa ; Gerald T. O’Connor, David J. Malenka, Hebe Quinton,
639 Bradykinin-Induced Preconditioning in Patients John F. Robb, Mirle A. Kellett, Jr., Samuel Shubrooks,
Undergoing Coronary Angioplasty Massoud A. Leesar, ; William A. Bradley, Michael J. Hearne, Mathew W.
Marcus F. Stoddard, Srinivas Manchtkalapud1, Roberto Bolh Watkins, David E. Wennberg, Bruce Hettleman, DanielJ .
651 Stented Segment Length as an Independent Predictor O’Rourke, Paul D. McGrath, Thomas Ryan, Jr., Peter
of Restenosis Yoshio Kobayashi, Joseph De Gregorio, VerLee, for the Northern New England Cardiovascular
Nobuyuki Kobayashi, Tatsuro Akiyama, Bernhard Reimers, Disease Study Group
Leo Finct, Carlo Di Marto, Antonio Colombo 692 Validation of Risk Adjustment Models for In-Hospital
660 Editorial Comment Long Lesions, Long Stents and the Percutaneous Transluminal Coronary Angioplasty
Long Process of Stent Optimization A/bert Schémig, Mortality on an Independent Data Set Mauro Moscucci,
Adnan Kastrati Gerald T. O'Connor, Stephen G. Ellis, David J. Malenka,
663 Creatine Kinase-MB Elevation After Coronary Jennifer Sievers, Eric R. Bates, David W. M. Muller,
Intervention Correlates With Diffuse Atherosclerosis, St coe W. Werns, Eva Kline Rogers, Dean Karavite,
and Low-to-Medium Level Elevation Has a Benign Kim A. Eagle
Clinical Course: Implications for Early Discharge After 698 Acute and Nine-month Clinical Outcomes After
Coronary Intervention Annapoorna Kini, Jonathan D. “Suboptimal” Coronary Stenting: Results From the
ce
6:
STent Anti-thrombotic Regimen Study (STARS) Lee Goldman, Pamela Coxson, Maria G. M. Hunink, Paula
Registry Donald E. Cutlip, Martin B. Leon, Kalon K. L. A. Goldman, Anna N. A. Tosteson, Murray Mittleman,
Ho, Paul C. Gordon, Alessandro Giambartolomei, Daniel J. Lawrence Wiliams, Milton C. Weinstein
Diver, David M. Lasorda, David O. Willams, Michelle M.
777 Independent and Incremental Value of Coronary
Fitzpatrick, April Desjardin, Jeffrey J. Popma, Richard E.
Artery Calcium for Predicting the Extent of
Kuntz, Donald S. Baim, for the Stent Anti-thrombotic
Angiographic Coronary Artery Disease: Comparison
Regimen Study Investigators
With Cardiac Risk Factors and Radionuclide Perfusion
707 One-Year Follow-Up After Intravascular Ultrasound
Imaging Axe/ Schmermund, Ali E. Denktas, John A.
Assessment of Moderate Left Main Coronary Artery
Rumberger, Timothy F. Christian, Patrick F. Sheedy II,
Disease in Patients With Ambiguous Angiograms
Kent R. Bailey, Robert 8. Schwartz
Andrea §. Abizaid, Gary S. Mintz, Alexandre Abizatd,
787 Racial Differences in the Significance of Coronary
Roxana Mehran, Alexandra J. Lansky, Augusto D. Pichard,
Calcium in Asymptomatic Black and White Subjects
Lowell F. Satler, Hongsheng Wu, Kenneth M. Kent,
With Coronary Risk Factors Terence M. Doherty, Weiyi
Martin B. Leon
Tang, Robert C. Detrano
716 Prognostic Importance of Lower Extremity Arterial
Disease in Patients Undergoing Coronary
Revascularization in the Bypass Angioplasty ATRIAL FUNCTION
Revascularization Investigation (BARI) Karen A. 795 Noninvasive Assessment of Left Atrial Maximum
dP/dt by a Combination of Transmitral and Pulmonary
Burek, Kim Sutton-Tyrrell, Maria Mori Brooks, Barbara
Venous Flow Satoshi Nakatani, Mario J. Garcia, Michael
Naydeck, Norma Keller, Mary Ann Sellers, Gary Roubin,
Rizena Jandovaé, Charanjit 8. Rthal S. Firstenberg, Leonardo Rodriguez, Richard A. Grimm,
722 A Randomized Trial of Elective Stenting After Neil L. Greenberg, Patrick M. McCarthy, Pieter M.
Vandervoort, James D. Thomas
Balloon Recanalization of Chronic Total Occlusions
Martin Hoher, Jochen Wéhrle, Olaf C. Grebe, Matthias 802 The Pulmonary Venous Systolic Flow Pulse—Its
Kochs, Hans-H. Osterhues, Vinzenz Hombach, Origin and Relationship to Left Atrial Pressure
Arnd B. Buchwald Otto A. Smiseth, Christopher R. Thompson, Kamol
Lohavanichbutr, Hilton Ling, James G. Abel, Robert T.
MYOCARDIAL ISCHEMIA
Mtyagishima, Sam V. Lichtenstein, John Bowering
730 Prognostic Implications of Myocardial Contractile
Reserve in Patients With Coronary Artery Disease and
ELECTROPHYSIOLOGY
Left Ventricular Dysfunction Faroog A. Chaudhry, Jason
810 Pretreatment With Verapamil in Patients With
T. Tauke, Renato §. Alessandrini, Gil Vardi, Michele A.
Persistent or Chronic Atrial Fibrillation Who
Parker, Robert O. Bonow
Underwent Electrical Cardioversion Antonio De
Simone, Giuseppe Stabile, Dino Franco Vitale, Pietro Turco,
MYOCARDIAL INFARCTION
739 Myoglobin, Creatine-Kinase-MB and Cardiac Maurizio Di Stasio, Ferdinando Petrazzuoh, Maurizio
Gasparini, Carmine De Mattes, Raffaele Rotunno,
Troponin-I 60-Minute Ratios Predict Infarct-related
Artery Patency After Thrombolysis for Acute Tommaso Di Napoli
Myocardial Infarction: Results from the Thrombolysis 815 The Effects of Biphasic and Conventional Monophasic
in Myocardial Infarction Study (TIMI) 10B Milenko J. Defibrillation on Postresuscitation Myocardial
Tanasyevic, Christopher P. Cannon, Elhott M. Antman, Function Wanchun Tang, Max Harry Weil, Shijie Sun,
Donald R. Wybenga, George A. Fischer, Christine Grudzien, Fittosht Yamagucht, Heitor P. Povoas, Andreja Marn Pernat,
C. Michael Gibson, James W. Winkelman, Eugene Joe Bisera
Braunwald, for the TIMI 10B Investigators
823 Sinus Node Function and Ventricular Repolarization
748 Acute Myocardial Infarction With Isolated ST-
During Exercise Stress Test in Long QT Syndrome
Segment Elevation in Posterior Chest Leads V7_,:
Patients With KvLQT1 and HERG Potassium
“Hidden” ST-Segment Elevations Revealing Acute
Channel Defects Heikki Swan, Matti Viitasalo, Kirsi
Posterior Infarction Shlomi Matetzky, Dov Freimark,
Pippo, Paivi Laitinen, Kimmo Kontula, Lauri Totvonen
Micha S. Feinberg, Ilya Novikov, Shmuel Rath, Babeth
Rabinowitz, Eleser Kaplinsky, Hanoch Hod
ENDOTHELIAL FUNCTION
830 The Deletion Genotype of the Angiotensin
CORONARY ARTERY DISEASE
754 Delayed Systolic Blood Pressure Recovery After I-Converting Enzyme Is Associated With an
Graded Exercise: An Independent Correlate of Increased Vascular Reactivity In Vivo and In Vitro
Angiographic Coronary Disease Scott A. McHam, Daniel Henrion, Joelle Benessiano, Ivan Philip, Sandrine
Thomas H. Marwick, Fredric J. Pashkow, Michael §. Lauer Vutllaumter-Barrot, Marc Iglarz, Gaetan Plantefeve, Didier
Chatel, Ulrich Hvass, Geneviéve Durand, Jean-Marie
760 Arterial Remodeling in the Left Coronary System: The
Desmonts, Philippe Amouyel, Bernard I. Lévy
Role of High-Density Lipoprotein Cholesterol A//en /.
Taylor, Allen P. Burke, Andrew Farb, Pouya Yousefi, Gray
T:. Malcom, John Smialek, Renu Virmani CARDIOMYOPATHY
837 Clinical Profiles of Four Large Pedigrees With
RISK FACTORS Familial Dilated Cardiomyopathy: Preliminary
768 The Relative Influence of Secondary Versus Primary Recommendations for Clinical Practice Kathy A.
Prevention Using the National Cholesterol Education Crispell, Anita Wray, Hanyu Ni, Deirdre J. Nauman,
Program Adult Treatment Panel II Guidelines Ray E. Hershberger
HEART FAILURE Converting Enzyme Inhibitor Captopril, Prevents the
848 Desensitization of the Pulmonary Adenylyl Cyclase Development of Lethal Ischemic Ventricular
System: A Cause of Airway Hyperresponsiveness in Arrhythmias in a Canine Model of Recent Myocardial
Congestive Heart Failure? Mathias M. Borst, Wilke Infarction Joseph J. Lynch, Jr., Gary L. Stump, Audrey A.
Beuthien, Carsten Schwencke, Paul LaRosée, Rainer Wallace, Carla A. Painter, Justina M. Thomas, Sandra E.
Marquetant, Markus Haass, Wolfgang Kubler, Kusma, Robert J. Gould, Wilam Grossman
Ruth H. Strasser
EDITOR’S PAGE
PEDIATRIC CARDIOLOGY
885 Who Should Be an Expert Witness? William W.
857 The Detection of Viral Genomes by Polymerase Chain
Parmley
Reaction in the Myocardium of Pediatric Patients
With Advanced HIV Disease Nei/ E. Bowles, Debra L.
Kearney, Jiyuan Ni, Antonio R. Perez-Atayde, Mark W.
SPECIAL SECTIONS
Kline, J. Timothy Bricker, Nancy A. Ayres, Steven E.
Lipshultz, Wiliam T. Shearer, Jeffrey A. Towbin ACC News
866 A New Strategy for the Surgical Treatment of Aortic 886 President’s Page: Meeting Improvement: A Guide to
Coarctation Associated With Ventricular Septal Defect Preparation of “Slides” for Presentation Arthur Garson, Jr.
in Infants Using an Absorbable Pulmonary Artery
Band Damien Bonnet, Juliana Patkai, Daniel Tamuisier, ACC/AHA Practice Guidelines
Jean Kachaner, Pascal Vouhé, Daniel Sidi 890 1999 Update: ACC/AHA Guidelines for the
Management of Patients With Acute Myocardial
EXPERIMENTAL STUDIES
Infarction Thomas J. Ryan, Chair
871 Arterialization of Human Vein Grafts Is Associated
912 ACC/AHA Guidelines for Ambulatory
With Tenascin-C Expression Kurt Wallner, Chen Li,
Electrocardiography Raymond J. Gibbons, Chair
Michael C. Fishbein, Prediman K. Shah, Behrooz G. Sharifi
876 EXP3174, the AII Antagonist Human Metabolite of
Losartan, but Not Losartan nor the Angiotensin- 949 LETTERS TO THE EDITOR
OCTOBER 1999 VOLUME 34 NUMBER 4
50TH ANNIVERSARY HISTORICAL MYOCARDIAL ISCHEMIA
ARTICLE 989 Low-Level Exercise Echocardiography Detects
959 A Century of Cardiac Arrhythmias: In Search of Contractile Reserve and Predicts Reversible
Dysfunction After Acute Myocardial Infarction:
Jason’s Golden Fleece Douglas P. Zipes
Comparison With Low-Dose Dobutamine
Echocardiography Ezienne P. Hoffer, Walthére Dewé,
CLINICAL STUDIES
Carmine Celentano, Luc A. Piérard
MYOCARDIAL INFARCTION
966 Recombinant Hirudin (Lepirudin) for the 998 Mechanisms and Clinical Significance of Transient
Atrioventricular Block During Dobutamine Stress
Improvement of Thrombolysis With Streptokinase in
Echocardiography Kuo-Chun Hung, Fun-Chung Lin,
Patients With Acute Myocardial Infarction: Results of
the HIT-4 Trial Kar/-Ludwig Neuhaus, G. Peter Molhoek, Ming-Shyan Chern, Hern-Jia Chang, I-Chang Hsieh,
Uwe Zeymer, Ulrich Tebbe, Karl Wegschetder, Rolf Schroder, Delon Wu
Anne Camez, G. Jan Laarman, Gilles M. Grollier, Dirk
1005 Improvement of Myocardial Blood Flow to Ischemic
J. A. Lok, Holger Kuckuck, Peter Lazarus, for the HIT-4
Regions by Angiotensin-Converting Enzyme Inhibition
Investi gators
With Quinaprilat IV: A Study Using [?°O] Water
974 Impaired Coronary Blood Flow in Nonculprit Arteries
Dobutamine Stress Positron Emission Tomography
in the Setting of Acute Myocardial Infarction C.
Christian A. Schneider, Eberhard Voth, Detlef Moka, Frank
Michael Gibson, Kathryn A. Ryan, Sabina A. Murphy,
M. Baer, Jacques Melin, Anne Bol, Rainer Wagner, Harald
Rebecca Mesley, Susan J. Marble, Robert P. Giughano,
Schicha, Erland Erdmann, Udo Sechtem
Christopher P. Cannon, Elliott M. Antman, Eugene
Braunwald, for the TIMI Study Group 1012 Prediction of Functional Recovery of Viable
983 Angiotensin-Converting Enzyme Inhibition Reduces Myocardium After Delayed Revascularization in
Monocyte Chemoattractant Protein-1 and Tissue Postinfarction Patients: Accuracy of Dobutamine
Factor Levels in Patients With Myocardial Infarction Stress Echocardiography and Influence of Long-Term
Hirofumi Soejima, Hisao Ogawa, Hirofumt Yasue, Koichi Vessel Patency Jean-Luc Monin, Jéréme Garot, Marielle
Kaikita, Keiji Takazoe, Koichi Nishiyama, Kenji Misumi, Scherrer-Crosbie, Jean Rosso, Anne-Marie Duval-Moulin,
Shinzo Miyamoto, Michthiro Yoshimura, Ktyotaka Patrick Dupouy, Emmanuel Teiger, Alain Castaigne, Jean-
Kugiyama, Shin Nakamura, Ichiro Tsujt Claude Cachin, Jean-Luc Dubois-Rande, Pascal Gueret
ACUTE CORONARY SYNDROMES Christodoulos Stefanadis, Eleni Triandaphyllidi, Konstantinos
Thrombin Generation After the Abrupt Cessation of Toutouzas, Pavlos Toutouzas
Intravenous Unfractionated Heparin Among Patients
With Acute Coronary Syndromes: Potential IMPLANTABLE DEFIBRILLATORS
Mechanisms for Heightened Prothrombotic Potential 1082 Long-Term Outcome of Patients With Unexplained
Richard C. Becker, Frederick A. Spencer, Youfu L1, Steven P. Syncope Treated With an Electrophysiologic-Guided
Ball, Yunsheng Ma, Thomas Hurley, James Hebert Approach in the Implantable Cardioverter- Defibrillator
Era Suneet Mittal, Sei Iwai, Kenneth M. Stein, Steven M.
INTERVENTIONAL CARDIOLOGY Markowitz, David J. Slotwiner, Bruce B. Lerman
1028 Effects of Adjunctive Balloon Angioplasty After 1090 Relative Effectiveness of the Implantable Cardioverter-
Intravascular Ultrasound-guided Optimal Directional Defibrillator and Antiarrhythmic Drugs in Patients
Coronary Atherectomy: The Result of Adjunctive With Varying Degrees of Left Ventricular Dysfunction
Balloon Angioplasty After Coronary Atherectomy Who Have Survived Malignant Ventricular
Study (ABACAS) Takahiko Suzuki, Hiroaki Hosokawa, Arrhythmias Michael J. Domanski, Sanjeev Sakseena,
Osamu Katoh, Tamotsu Fujita, Katsumi Ueno, Shinichi
Andrew E. Epstein, Alfred P. Hallstrom, Michael A.
Takase, Kenshi Fujii, Hideo Tamai, Tadanori Aizawa, Brodsky, Soo Kim, Scott Lancaster, Eleanor Schron,
Tetsu Yamaguchi, Hiroyuki Kurogane, Mikthiro Kyima, for the AVID Investigators
Hirotaka Oda, Etsuo Tsuchikane, Tomoaki Hinohara, Peter
1096 Editorial Comment Learning More About Indications for
Fitzgerald, for the ABACAS Investigators
Implantable Cardioverter-Defibrillator Robert J.
1036 Early Recovery of Coronary Flow Reserve After Myerburg, Agustin Castellanos
Stent Implantation as Assessed by Positron Emission
Tomography Istvan Kosa, Rudolf Blasini, Jan Schnetider- ELECTROPHYSIOLOGY
Eicke, Timm Dickfeld, Franz J. Neumann, Sibylle Ziegler, 1099 Detection of Myocardial Injury During Radiofrequency
Ichiro Matsunari, Jodi Neverve, Albert Schémig, Catheter Ablation by Measuring Serum Cardiac
Markus Schwaiger Troponin I Levels: Procedural Correlates Anzonis S.
1042 Editorial Comment Nuclear Cardiology After Angioplasty Manolis, Vassilis Vasstltkos, Themos Maounts, Helen Melita-
and Stent Placement: Beyond Sensitivity and Manolis, Lefteris Psarros, Alex Hattasos, Dennis V. Cokkinos
Specificity Dante E. Manyari, Dennis P. Humen, 1106 Large T Wave Inversion and QT Prolongation
Merril Knudtson Associated With Pulmonary Edema: A Report of Nine
Cases Laszlo Littmann
1045 Tissue Characteristics of Restenosis After
Percutaneous Transluminal Coronary Angioplasty in 1111 In-Hospital Versus Out-of-Hospital Presentation of
Diabetic Patients Pedro R. Moreno, John T. Fallon, Life-Threatening Ventricular Arrhythmias Predicts
Survival: Results From the AVID Registry Andrew E.
Alvaro M. Murcia, Miltiadis N. Leon, Hector Simosa,
Valentin Fuster, Igor F. Palacios Epstein, Judy Powell, Qing Yao, Celeste Ocampo, Scott
Lancaster, Yves Rosenberg, David 8. Cannom, John M.
1050 Final Results of the STent Versus Directional
Herre, H. Leon Greene, and the AVID Investigators
Coronary Atherectomy Randomized Trial (START)
Etsuo Tsuchikane, Satoru Sumitsuji, Nobuhisa Awata,
HYPERTROPHIC CARDIOMYOPATHY
Toshinort Nakamura, Tomoko Kobayashi, Masahiro Izumi,
1117 Electromechanical Left Ventricular Behavior After
Satoru Otsujt, Hitone Tateyama, Makoto Sakura,
Nonsurgical Septal Reduction in Patients with
Tohru Kobayashi
Hypertrophic Obstructive Cardiomyopathy Michael Y.
1058 Editorial Comment When Should We Start Randomized Henein, Christine A. O'Sullivan, Ihab 8. Ramzy, Ulrich
Trials for New Devices? William W. O’Nei/l Sigwart, Derek G, Gibson
1061 Economic Impact of GPIIB/IIIA Blockade After 1123 Changes in Left Ventricular Filling and Left Atrial
High-Risk Angioplasty: Results from the RESTORE Function Six Months After Nonsurgical Septal
Trial William S. Weintraub, Steven Culler, Stephen J. Reduction Therapy for Hypertrophic Obstructive
Boccuzzi, John R. Cook, Andrzej S. Kosinski, David J. Cardiomyopathy Sherif F. Nagueh, Nasser M. Lakkis,
Cohen, Joy Burnette, for the RESTORE Trial Study Group Katherine J. Middleton, Donna Killip, William A. Zoghhi,
Miguel A. Quinones, Wiliam H. Spencer III
1067 Periprocedural Quantitative Coronary Angiography
After Palmaz-Schatz Stent Implantation Predicts the
VALVE DISEASE
Restenosis Rate at Six Months: Results of a Meta-
analysis of the Belgian Netherlands Stent Study 1129 Functional Anatomy of Mitral Regurgitation: Accuracy
and Outcome Implications of Transesophageal
(BENESTENT) I, BENESTENT II Pilot,
Echocardiography Maurice Enriquez-Sarano, William K.
BENESTENT II and MUSIC Trials Patrick W.
Freeman, Christophe M. Tribouilloy, Thomas A. Orszulak,
Serruys, I. Patrick Kay, Clemens Disco, Niteen V.
Byoy K. Khandheria, James B. Seward, Kent R. Bailey,
Deshpande, Pim J. de Feyter, on behalf of the BENESTENT
A. Jamil Tajik
I, BENESTENT II Pilot, BENESTENT II and MUSIC
Study Groups 1137 Progression of Mitral Regurgitation: A Prospective
Doppler Echocardiographic Study Maurice Enriquez-
CORONARY ARTERY DISEASE Sarano, Arsene-Joseph Basmadjian, Andrea Rosst, Kent R.
1075 Coronary Artery Distensibility in Diabetic Patients Bailey, James B. Seward, A. Jamil Tajik
With Simultaneous Measurements of Luminal Area 1145 Mitral Balloon Valvotomy for Patients With Mitral
and Intracoronary Pressure: Evidence of Impaired Stenosis in Atrial Fibrillation: Immediate and Long-
Reactivity to Nitroglycerin Manolis Vavuranakis, Term Results Mi/tiadis N. Leon, Lari C. Harrell, Hector
F. Simosa, Nasser A. Mahdi, Asad Pathan, MD, Julio EXPERIMENTAL STUDIES
Lopez-Cuellar, Ignacio Inglessis, Pedro R. Moreno, 1208 Differential Effects of a- and y-Tocopherol on Low-
Igor F. Palacios Density Lipoprotein Oxidation, Superoxide Activity,
1153 Low Prevalence of Valvular Heart Disease in 226 Platelet Aggregation and Arterial Thrombogenesis
Phentermine-Fenfluramine Protocol Subjects Tom Saldeen, Dayuan Li, and Jawahar L. Mehta
Prospectively Followed for up to 30 Months Andrew
1216 Editorial Comment Antioxidant Vitamins: Sorting Out the
J. Burger, Howard B. Sherman, Mark J. Charlamb,
Good and the Not So Good Cam Patterson, Scott
Juhee Kim, Laura A. Asinas, Stacy R. Flickner,
Ballinger, George A. Stouffer, Marshall S. Runge
George L. Blackburn
1219 The Influence of Low Afterload on the Nature of the
1159 Editorial Comment Fen/Phen and Valvular Heart Disease:
Stress-Velocity Relationship Danié/ De Wolf, Luc
If It Sounds Too Bad To Be True, Perhaps It Isn’t
Foubert, Yves Van Belleghem, Kathy Mareels, Dirk Matthys,
Nelson B. Schiller
Henri Verhaaren, Guido Van Nooten
BYPASS SURGERY
1163 The Influence of Abciximab Use on Clinical Outcome EDITORIAL
After Aortocoronary Vein Graft Interventions Verghese 1226 The Language of Lysis: A Proposal to Standardize the
Mathew, Diane E. Grill, Christopher G. Scott, J. Aaron Nomenclature Burton E. Sobel
Grantham, Henry H. Ting, Kirk N. Garratt,
David R. Holmes, Jr.
EDITOR’S PAGE
1228 Going, Going ... Gone William W. Parmley
HEART FAILURE
1170 Neuroendocrine Activation in Heart Failure Is
Modified by Endurance Exercise Training Randy W.
Braith, Michael A. Welsch, Matthew S. Feigenbaum, Heidi SPECIAL SECTIONS
A. Kluess, Carl J. Pepine
ACC News
1229 President’s Page: Performance Measures and Our “Art”
GERIATRIC CARDIOLOGY
Arthur A. Garson, Jr.
1176 Angiotensin I—Converting Enzyme and Plasminogen
Activator Inhibitor-1 Gene Variants: Risk of Mortality 1231 Education Update: 1999
and Fatal Cardiovascular Disease in an Elderly
Population-Based Cohort Bastiaan T. Hetjmans, Rudi
ACC/AHA Practice Guidelines
G. J. Westendorp, Dick L. Knook, Cornelis Klufi,
1262 ACC/AHA Guidelines for Coronary Artery Bypass
P. Eline Slagboom
Graft Surgery: A Report of the American College of
Cardiology/American Heart Association Task Force on
PULMONARY HYPERTENSION
Practice Guidelines (Committee to Revise the 1991
1184 The Effects of Chronic Prostacyclin Therapy on
Guidelines on Coronary Artery Bypass Graft Surgery)
Cardiac Output and Symptoms in Primary Pulmonary
Kim A. Eagle, Co-Chair, Robert A. Guyton, Co-Chair
Hypertension Stuart Rich, Vallerie V. McLaughlin
1188 Effect of Orally Active Prostacyclin Analogue on
AHA/ACC Scientific Statement
Survival of Outpatients With Primary Pulmonary
Hypertension Noritoshi Nagaya, Masaaki Uematsu, 1348 AHA/ACC Scientific Statement: Assessment of
Cardiovascular Risk by Use of Multiple-Risk-Factor
Yoshiaki Okano, Toru Satoh, Shingo Kyotani, Fumio
Assessment Equations: A Statement for Healthcare
Sakamaki, Norifumt Nakanishi, Kunio Mtyatake,
Professionals From the American Heart Association
Takeyoshi Kunieda
and the American College of Cardiology Scot M.
Grundy, Richard Paternak, Philip Greenland, Sidney Smith,
NEW METHODS
Valentin Fuster
1193 Validation of a New Noninvasive Method (Contrast-
Enhanced Transthoracic Second Harmonic Echo Dopp-
ler) for the Evaluation of Coronary Flow Reserve:
Call to Action
Comparison With Intracoronary Doppler Flow Wire
1360 Hypertension Detection, Treatment and Control: A
Carlo Caiati, Cristiana Montaldo, Norma Zedda, Roberta
Call to Action for Cardiovascular Specialists Danie/
Montisci, Massimo Ruscazio, Giorgio Lat, Mauro Cadeddu,
Levy (lead author), C. Noel Bairey Merz, Robert J. Cody
Luigi Meloni, Sabino Ilceto
(chair), Fetnat M. Fouad-Tarazi, Charles K. Francis, Marc
A. Pfeffer, Neal A. Scott, H. J. C. Swan, Malcolm P. Taylor,
ENDOTHELIAL FUNCTION
Myron H. Weinberger
1201 Gene Transfer of Nitric Oxide Synthase: Effects on
Endothelial Biology Josef Niebauer, Jézef Dulak, Jason R.
Chan, Philip S. Tsao, John P. Cooke 1363 CORRECTIONS
NOVEMBER 1, 1999 VOLUME 34. NUMBER 5
50TH ANNIVERSARY HISTORICAL 1443 Hyperinsulinemic Hypoalphalipoproteinemia as a New
ARTICLE Indicator for Coronary Heart Disease Keijiro Saku, Bo
1365 Myocardial Oxygen Consumption: The Quest for its Zhang, Kazuyuki Shirat, Shiro Jimi, Kazuhiko Yoshinaga,
Kikuo Arakawa
Determinants and Some Clinical Fallout
Eugene Braunwald 1552 Endothelial and Metabolic Characteristics of Patients
With Angina and Angiographically Normal Coronary
REVIEW ARTICLE
Arteries: Comparison With Subjects With Insulin
1369 The Necessity for Recognition and Treatment of Resistance Syndrome and Normal Controls §PierMarco
Patients With “Mild” Hypertension Edward D. Frohlich
Piatti, Gabriele Fragasso, Lucilla D. Monti, Andrea Caumo,
CLINICAL STUDIES Chuong Van Phan, Gtamptetro Valseccht, Sabrina Costa,
Elena Fochesato, Guido Pozza, Antonio E. Pontitrol1,
MYOCARDIAL INFARCTION Sergio Chierchta
1378 Twenty Year Trends (1975-1995) in the Incidence,
In-hospital and Long-Term Death Rates Associated CORONARY ECTASIA
With Heart Failure Complicating Acute Myocardial 1461 Exercise-Induced Myocardial Ischemia in Isolated
Infarction: A Community-Wide Perspective Frederick Coronary Artery Ectasias and Aneurysms (“Dilated
A. Spencer, Theo E. Meyer, Robert J. Goldberg, Jorge Coronaropathy”) Dietmar Kriiger, Ulrich Stierle, Gunhild
Yarzebski, Mark Hatton, Darleen Lessard, Joel M. Gore Herrmann, Riidiger Simon, Abdolhamid Sheikhzadeh
1388 Beta-Blocker Therapy for Secondary Prevention
of Myocardial Infarction in Elderly Diabetic Patients INTERVENTIONAL CARDIOLOGY
1471 The Relationship Between Operator Volume and
Jersey Chen, Thomas A. Marciniak, Martha J. Radford, Yun
Outcomes After Percutaneous Coronary Interventions
Wang, Harlan M. Krumholz
in High Volume Hospitals in 1994-1996: The
1395 Overcoming Thrombolytic Resistance: Rationale and
Northern New England Experience David J. Malenka,
Initial Clinical Experience Combining Thrombolytic
Paul D. McGrath, David E. Wennberg, Thomas J. Ryan,
Therapy and Glycoprotein IIb/IIIa Receptor
Jr., Mirle A. Kellett, Samuel J. Shubrooks, Jr.. Wiliam A.
Inhibition for Acute Myocardial Infarction
Bradley, Bruce D. Hettlemen, John F. Robb, Michael
Christopher P. Cannon
J. Hearne, Theodore M. Silver, Matthew W. Watkins, John
1403 Determinants of Coronary Blood Flow After R. O'Meara, Peter N. VerLee, Dantel J. O'Rourke, for the
Thrombolytic Administration C. Michael Gibson, Northern New England Cardiovascular Disease Study Group
Sabina Murphy, Ian B. A. Menown, Rafael F. Sequeira,
1481 Editorial Comment Percutaneous Coronary Interventions:
Robert Greene, Frans Van de Werf, Marc J. Schweiger, Magdi
Heed the American College of Cardiology Volume
Ghah, Martin J. Frey, Kathryn A. Ryan, Susan J. Marble, Recommendations, But Strive to Improve Quality
Robert P. Giughano, Elhott M. Antman, Christopher P.
Edward L. Hannan
Cannon, Eugene Braunwald, for the TIMI Study Group
1484 Short- and Long-Term Evolution of Unstented
1413 ST-Segment Monitoring With Continuous 12-Lead Nonocclusive Coronary Dissection After Coronary
ECG Improves Early Risk Stratification in Patients
Angioplasty Alberto Cappelletti, Alberto Margonato,
With Chest Pain and ECG Nondiagnostic of Acute
Giuseppe Rosano, Alessandra Mailhac, Fabrizio Veglia,
Myocardial Infarction Tomas Jernberg, Bertil Lindahl,
Antonio Colombo, Sergio Lorenzo Chierchta
Lars Wallentin
1489 Editorial Comment To Stent or Not to Stent—That Is the
1420 Effect of Glycoprotein IIb/IIIa Receptor Blockade on
Question Michael H. Sketch, Sr.
Platelet-Leukocyte Interaction and Surface Expression
1490 Propensity and Mechanisms of Restenosis in Different
of the Leukocyte Integrin Mac-1 in Acute Myocardial
Coronary Stent Designs: Complementary Value of the
Infarction Franz-Josef Neumann, Dietlind Zohlnhéfer,
Analysis of the Luminal Gain-Loss Relationship
Letla Fakhoury, Ilka Ott, Meinrad Gawaz, Albert Schimig
Javier Escaned, Javier Gotcolea, Fernando Alfonso,
1427 Evidence Against a Role of Physiological
Marta José Perez-Vizcayno, Rosana Hernandez,
Concentrations of Estrogen in Post-Myocardial
Antonio Fernandez-Ortiz, Camino Banuelos, Carlos Macaya
Infarction Remodeling Stephanie Hiigel, Martin Reincke,
Hinrthk Strémer, Johannes Winning, Michael Horn, Charlotte A FOUR-YEAR FOLLOW-UP
Dienesch, Patricia Mora, Harald H. H. W. Schmidt, Bruno 1498 Randomized Comparison of Coronary Stent
Allolio, Stefan Neubauer Implantation and Balloon Angioplasty in the
Treatment of De Novo Coronary Artery Lesions
CORONARY ARTERY DISEASE (START): A Four-Year Follow-up Amadeo Betriu,
1435 Circulating Chlamydia pneumoniae DNA as a Predictor
Monica Masotti, Antoni Serra, Joaquin Alonso,
of Coronary Artery Disease Yuk-ki Wong, Keith D. Francisco Fernandez-Avilés, Federico Gimeno, Thierry
Dawkins, Michael E. Ward Colman, Javier Zueco, Juan L. Delcan, Eulogio Garcia,
1440 Editorial Comment Chlamydia pneumoniae Infection and José Calabuig
Coronary Artery Disease Juan Carlos Kashi, 1507 Does Angiography Six Months After Coronary
A. John Camm Intervention Influence Management and Outcome?