Table Of Content

Neurobiology Volume Contents Vol. 50, No. 1, January 2002 Contents Estradiol-Induced Phosphorylation of ERK1/2 in Explants of the Mouse Cerebral Cortex: The Roles of Heat Shock Protein 90 (Hsp90) and MEK2 / 1 Gy6érgy Sétalé Jr., Meharvan Singh, Xiaoping Guan, and C. Dominique Toran-Allerand Sympathetic Neuronal Survival Induced by Retinal Trophic Factors / 13 Ricardo A.M. Reis, Mauricio C. Cabral da Silva, Nelson E. Loureiro dos Santos, Edward Bampton, Jeremy S.H. Taylor, Fernando G. de Mello, and Rafael Linden Sexual Dimorphism in Neuromuscular Junction Size on a Muscle Used in Courtship by Green Anole Lizards / 24 Erin L. O’Bryant and Juli Wade Hydroxyurea-Induced Partial Mushroom Body Ablation in the Honeybee Apis mellifera: Volumetric Analysis and Quantitative Protein Determination / 31 Dagmar Malun, Niels Plath, Martin Giurfa, Ariane D. Moseleit, and Uli Miller Calcium Oscillations in Neocortical Astrocytes under Epileptiform Conditions / 45 Ayumu Tashiro, Jesse Goldberg, and Rafael Yuste Intracellular Trafficking of a Tagged and Functional Mammalian Olfactory Receptor / 56 Lidija Ivic, Cen Zhang, Xinmin Zhang, Sung Ok Yoon, and Stuart Firestein Dual Role for Calcium in Agrin Signaling and Acetylcholine Receptor Clustering / 69 Lucia S. Borges, Young Lee, and Michael Ferns Cover: Confocal microscope images of HEK 293 cells transfected with a construct containing the rat 17 olfactory receptor tagged with Flag at the N-terminus and EGFP separated from Flag::I17 by an IRES sequence. The cells were labeled with red fluorescent anti-Flag and blue fluorescent anti-EGFP antibodies. Green fluorescence comes from the independent, soluble EGFP. In permeabilized cells (top), both anti- Flag (red) and anti-EGFP (blue) antibodies cross the plasma membrane and label intracellularly located fusion protein and EGFP. In unpermeabilized cells (bottom), although EGFP is present throughout the cell, only the red anti-Flag labeling is visible, indicating the proper membrane localization of the Flag::17 protein, with its N-terminal Flag epitope located extracellularly. See the article by Ivic et al. on pages 56-68. Vol. 50, No. 2, February 5, 2002 Contents Survival of Bundleless Hair Cells and Subsequent Bundle Replacement in the Bullfrog’s Saccule / 81 Jonathan E. Gale, Jason R. Meyers, Ammasi Periasamy, and Jeffrey T. Corwin The Organization of Synaptic Vesicles at Tonically Transmitting Connections of Locust Visual Interneurons / 93 Gerd Leitinger and Peter J. Simmons Steps in the Formation of a Bipolar Outgrowth Pattern by Cultured Neurons, and Their Substrate Dependence / 106 Francisco F. de-Miguel and Javier Vargas Regulated vnd Expression Is Required for Both Neural and Glial Specification in Drosophila / 118 Dervla M. Mellerick and Victoria Modica The Function and the Expression of Forebrain GABA, Receptors Change with Hormonal State in the Adult Mouse / 137 Juan Carlos Jorge, Kerry L. McIntyre, and Leslie P. Henderson Rare and Spatially Segregated Release Sites Mediate a Synaptic Interaction between Two Identified Network Neurons / 150 Marie-Jeanne Cabirol-Pol, Denis Combes, Valérie S. Fénelon, John Simmers, and Pierre Meyrand A Neuronal Inhibitory Domain in the N-Terminal Half of Agrin / 164 John L. Bixby, Kristine Baerwald-De La Torre, Cong Wang, Fritz G. Rathjen, and Markus A. Riiegg Cover: A scanning electron micrograph of the surface of a bullfrog’s saccule that shows a hair bundle and cuticular plate that have separated from the soma of a gentamicin-damaged hair cell. Exposure to short-term, low-dose gentamicin causes loss of the sensory apparatus from hair cells, which can survive and recover. Electron microscopy, time-lapse, and multi-photon recordings were used to observe bundle separation, survival of bundleless hair cells, and repair of damaged hair cell surfaces as described in Gale et al., pages 81-92. Vol. 50, No. 3, February 15, 2002 Contents FAST TRACK Injury-Induced Spinal Motor Neuron Apoptosis Is Preceded by DNA Single- Strand Breaks and Is p53- and Bax-Dependent / 181 Lee J. Martin and Zhiping Liu Muscle-Derived Neurotrophin-3 Reduces Injury-Induced Proprioceptive Degeneration in Neonatal Mice / 198 D. E. Wright, J. M. Williams, J. T. McDonald, J. A. Carlsten, and M. D. Taylor Neural Cell Differentiation from Retinal Pigment Epithelial Cells of the Newt: An Organ Culture Model for the Urodele Retinal Regeneration / 209 Yoko Ikegami, Sanae Mitsuda, and Masasuke Araki Targeted Expression of Tetanus Neurotoxin Interferes with Behavioral Responses to Sensory Input in Drosophila / 221 Andreas Keller, Sean T. Sweeney, Troy Zars, Cahir J. O’Kane, and Martin Heisenberg Spike-Triggered Dendritic Calcium Transients Depend on Synaptic Activity in the Cricket Giant Interneurons / 234 Hiroto Ogawa, Yoshichika Baba, and Kotaro Oka Pharmacological Evidence of GABAergic Regulation of Specific Behaviors in Drosophila melanogaster / 245 Sandra M. Leal and Wendi S. Neckameyer Cover: The cell death protein p53 is induced in adult rat lumbar motor neurons after sciatic nerve avulsion. Immunoperoxidase staining for p53 (brown labeling) shows the nuclear accumulation of p53 by 5 days after the injury. p53 decorates strands within the nucleus (top motor neuron), consistent with its DNA binding function. Motor neuron apoptosis after nerve injury is p53-dependent and may be induced by early DNA damage. The finding that motor neuron death may be DNA damage-induced, p53-mediated apoptosis is relevant to the mechanisms of motor neuron death signaling in ALS and spinal cord injury. See the article by Martin and Liu on pages 181-197. Vol. 50, No. 4, March 2002 Contents Local Calcium Changes Regulate the Length of Growth Cone Filopodia / 263 Su Cheng, Matthew S. Geddis, and Vincent Rehder Chronic Alterations in Serotonin Function: Dynamic Neurochemical Properties in Agonistic Behavior of the Crayfish, Orconectes rusticus / 276 Jules B. Panksepp and Robert Huber BMP-2 and cAMP Elevation Confer Locus Coeruleus Neurons Responsiveness to Multiple Neurotrophic Factors / 291 Julia Reiriz, Pontus C. Holm, Jordi Alberch, and Ernest Arenas Neural Progenitor Cells of the Neonatal Rat Anterior Subventricular Zone Express Functional GABA, Receptors / 305 R.R. Stewart, G.J. Hoge, T. Zigova, and M.B. Luskin Striatopallidal Neurons Are Selectively Protected by Neurturin in an Excitotoxic Model of Huntington’s Disease / 323 Sonia Marco, Esther Pérez-Navarro, Eduard Tolosa, Ernest Arenas, and Jordi Alberch Novel UNC-44 AO13 Ankyrin Is Required for Axonal Guidance in C. elegans, Contains Six Highly Repetitive STEP Blocks Separated by Seven Potential Transmembrane Domains, and Is Localized to Neuronal Processes and the Periphery of Neural Cell Bodies / 333 Anthony J. Otsuka, Pratumtip Boontrakulpoontawee, Natalie Rebeiz, Marc Domanus, Dawn Otsuka, Nena Velamparampil, Sabrina Chan, Marshall Vande Wyngaerde, Sarah Campagna, and Andrea Cox Author Index to Volume 50 / 353 Subject Index to Volume 50 / 355 Volume Contents / I Cover: Pseudocolor image of a Helisoma B5 growth cone that is co-injected with the Ca°” indicator, calcium green, and the Ca~" cage, NP-EGTA. The image was taken on a confocal microscope (LSM 510, Carl Zeiss, Inc.) and represents the first image in a time series taken immediately after the photo-release of Ca** from NP-EGTA (See Fig. 1B of the article on page 266 by Cheng et al.) Ca?* was photo-released for 0.4 seconds with the 351 and 364 nm lines of an UV laser (Enterprise, Coherent Laser Group) focused on a 60 um? area in the central domain of the growth cone. Photo-release of Ca* in different regions of growth cones was performed in this study to determine how spatial and temporal elevations of Ca** influence growth cone behavior.