Journal of Labelled Compounds and Radiopharmaceuticals 2002: Vol 45 Table of Contents

11 Pages·2002·0.42 MB·English

JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS
J Label Compd Radiopharm 2002; 45: 1303-1312
Journal
of
LABELLED COMPOUNDS
and
RADIOPHARMACEUTICALS
The Official Journal of the International Isotope Society
Volume Contents
Volume 45, Issue Numbers 1-14
Copyright © 2002 John Wiley & Sons, Ltd
1304 Volume Contents
ISSUE No. 1
Research Articles
Fluorine-18 labeling of peptide nucleic acids
B. Kuhnast, F. Dolle and B. Tavitian. 1
Preparation and a simple one-step purification of [His*-mono-’^^I-Tyr’°,Nle^^]-hGHRH
(1-32)-NH2
J. Gardi, J. M. Krueger and R. C. Speth. 13
Synthesis of deoxyadenosine-5'-(^^S)-thiomonophosphate [dAMP('^^S)] of high specific
activity — a key intermediate for the synthesis of Sp-deoxyadenosine-5'-(a-^^S)-
thiotriphosphate [Sp-dATP (a-‘^^S)]
K. M. Mathew, S. Ravi, C. V. Sontakke and H. Chander. 19
Synthesis of [C^H^Jmethotrexate and [C'H^JT-hydroxymethotrexate
C. S. Elmore, D. C. Dean, Y. Zhang, C. Gibson, H. Jenkins, A. N. Jones and
D. G. Melillo. 29
Synthesis of ["Cjatipamezole, a potential PET ligand for the a2-adrenergic receptor in
the brain
D. Roeda, H. T. Sipild, Y. Bramoulle, J. D. Enas, F. Vaufrey, F. Dolle and
C. Crouzel. 37
A novel and efficient asymmetric synthesis of carbon-14 labeled {S, 5')-2,7-di-boc-
diamino[l,8-'"‘C2]suberic acid
A. J. Villani, D. Saunders, A. Y. L. Shu and J. R. Heys. 49
Tritiation of SR 141716 by metallation-iodination-reduction: tritium-proton nOe study
FI. H. Seltzman, F. I. Carroll, J. P. Burgess, C. D. Wyrick and D. F. Burch. 59
Synthesis of deuterated-BCX-1777, a potent inhibitor of purine nucleoside
phosphorylase
H. S. Kezar III, T. L. Hutchison, P. C. Tyler and P. E. Morris Jr.! 71
Synthesis of all-/rart.v-[10'-‘^H]-8'-apo-/i-carotenoic acid
P. V. Reddy, M. Rahago-Smith and B. Borhan. 79
ISSUE No. 2
Review Article
Radiohalogenated carbohydrates for use in PET and SPECT
M. J. Adam. 167
Research Articles
Synthesis and characterization of 4,6-dichloroindole-based radioligands for imaging
the glycine site of the NMDA ion channel
R. N. Waterhouse, A. Sultana, N. Guo, B. Lee, N. Simpson, L. Collier and
M. Larue lie. 91
Synthesis of ''^C-labelled cinnamonitrile
E. M. Zippi and E. Kamperman. 103
Volume Contents 1305
Synthesis of morphine-[A^-methyl-'‘*C]-6-)ff-D-glucuronide
J. R. Ferguson, S. J. Hollis, G. A. Johnston, K. W. Lumbard and A. V. Stachulski. 107
Synthesis, labelling and biological characteristics of derivatives of
Mercaptoacetyltriglycine with two amide functions
S. M. Okarvi, K. Verbeke, P. Adriaens and A. M. Verbruggen. 115
Synthesis of and ‘^N multilabeled 5-aminolevulinic acid
K. lida and M. Kajiwara. 139
Synthesis of''H, '^C and '-'Q labelled Sch 58235
D. Hesk, G. Bignan, J. Lee, J. Yang, K. Voronin, C. Magatti, P. McNamara,
D. Koharski, S. Hendershot, S. Saluja and S. Wang. 145
"C labelling of AG957 — a potential tyrphostin radiotracer for PET
U. Ackermann, H. J. Tochon-Danguy, K. Young, J. I. Sachinidis, J. G. Chan and
A. M. Scott. 157
ISSUE No. 3
Research Articles
Synthesis of (±) 3-(6-nitro-2-quinolinyl)-[9-methyl-“C]-3,9-diazabicyclo-[4.2. l]-nonane
(["C-methyl]NS 4194)
S. B. Jensen, D. Bender, D. F. Smith, J. Scheel-Kriiger, E. 0. Nielsen, G. M. Olsen,
D. Peters and A. Gjedde. 181
Isotopically labelled tropane alkaloids. The synthesis of (7?5)-[3', 3'-^H2]- and
(/?5)-[r-'^C, 3', 3'-^H2]-hyoscyamines for metabolism studies in plants
S. Patterson and D. O’Hagan. 191
Novel synthesis of [l-''C]7-vinyl-y-aminobutyric acid ([1-"C]GVG) for pharmacokinetic
studies of addiction treatment
Z. Zhang, Y.-S. Ding, A. R. Studenov, M. R. Gerasimov and R. A. Ferrieri. 199
Preparation of N4-["C]methyl-ciprofloxacin for positron emission tomography studies
P. Goethals and A. Volkaert. 213
C-Terminal '^F-fluoroethylamidation exemplified on [Gly-OH'^j oxytocin
M. Jelinski, K. Hamacher and H. H. Coenen. 217
Solid phase preparations of ‘^‘^"’Tc labeled radiopharmaceuticals
P. S. Rao, H. Li, K. C. Reddy and M. L. Thakur. 231
Synthesis of selectively '^N- or '^C-labelled malachite green
S. C. DeFina and T. Dieckmann. 241
Microbiotic synthesis of '"‘C-ringlabelled aminodinitrotoluenes (ADNT) and
diaminonitrotoluenes (DANT)
M. Kroger and G. Fels. 249
Photoconjugation of 3-azido-5-nitrobenzyl-['^F]fluoride to an oligonucleotide aptamer
C. W. Lange, H. F. VanBrocklin and S. E. Taylor. 257
Abstract from the 9th Conference of the Central European Division e.V. of the
International Isotope Society — Bad Soden, Germany, June 2001
R. Koermeling. 269
1306 Volume Contents
ISSUE No. 4
Review Articles
Proton and metal-ion activation of C-H exchange in five-membered azoles
E. Buncel and I. Onyido. 291
Specific labelling of nucleosides and nucleotides with '^C and '^N
J. Milecki. 307
Research Articles
A combined loop-SPE method for the automated preparation of [“Cjdoxepin
R. Iwata, C. Pascali, A. Bogni, K. Yanai, M. Kato, T. Ido and K. Ishiwata. 271
A convenient synthesis of ["CJparaquat and other [A-methyl-"C]bisquaternary
ammonium compounds
D. M. Jewett and M. R. Kilbourn. 281
Deterioration of storage phosphor screens with use
I. Reinprecht, M. Windisch and M. Fahnestock. 339
Synthesis of A-(2,3-dihydro-1 -["‘C]methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-
3-yl)-benzamide and A-(2,3-dihydro-l-[’'*C]methyl-2-oxo-5-phenyl-lH-l,4-
benzodiazepin-3-yl)-A-[''*C]methyl-benzamide as novel carbon-14 labelled CCK
antagonists
H. Matlouhi, A. Khalaj, R. Dowlatahadi and G. Shirvani. 347
Radiolabelling of NNC 05-1869, a compound for treatment of diabetic neuropathy
J. S. Valshorg and C. Foged. 351
ISSUE No. 5
Research Articles
Regio- and stereoselective preparation of ascomycin-d, and FK 506-d,
M. Acemoglu, H. Andres and T. Moenius. 361
Synthesis of A-(2-chloro-3,4-dimethoxybenzylideneamino)guanidinium acetate
M. Almeida, A. Roman and T. Lundstedt. 371
Synthesis of two novel oxocyclam-binding technetium complexes containing an
analogue of cocaine
F. Turpin, F. Masri, F. Riche, E. Berthommier, P. Emond, M. Vidal, P. Auzeloux,
C. Loc’h, N. Neuquelman and L. Mauclaire. 379
Synthesis of A-(2-chloro-5-methylthiophenyl)-A'-(3-methyl-thiophenyl)-A'-
pH3]methylguanidine, {[^H3]CNS-5161}
A. R. Gibbs, H. Morimoto, H. F. VanBrocklin, P. G. Williams and A. Biegon. 395
Synthesis and characterization of [vinylidine-^H] (—)-a-kainic acid at high specific
activity
D. G. Ahern, R. J. Seguin and C. N. Filer. 401
Synthesis, radiolabelling and biological evaluation of terminal oxamide derivatives of
mercaptoacetyltriglycine
S. M. Okarvi, P. Torfs, P. Adriaens and A. M. Verbruggen. 407
Volume Contents 1307
Synthesis of 3-[(2S)-azetidin-2-ylmethoxy]-5-[*'C]-methylpyridine, an analogue of
A-85380, via a Stille coupling
F. Karimi and B. Langstrom. 423
Fast ['**F]FDG synthesis by alkaline hydrolysis on a low polarity solid phase support
C. Lemaire, Ph. Damhaut, B. Lauricella, C. Mosdzianowski, J-L. Morelle,
M. Monclus, J. van Naemen, E. Mulleneers, J. Aerts, A. Plenevaux, C. Brihaye
and A. Luxen. 435
ISSUE No. 6
Review Article
Radiohalogen incorporation into organic systems
R. Bolton. 485
Research Articles
Synthesis of MMP inhibitor radiotracers [''C]methyl-CGS 27023A and its analogs,
new potential PET breast cancer imaging agents
X. Fei, Q-H. Zheng, G. D. Hutchins, X. Liu, K. L. Stone, K. A. Carlson. B. H. Mock,
W. L. Winkle, B. E. Glick-Wilson, K. D. Miller, R. S. Fife, G. W. Sledge, H. B. Sun
and R. E. Carr. 449
Radiosynthesis of [' 'C]paclitaxel
H. T. Ravert, R. W. Klecker Jr, J. M. Collins, W. B. Mathews, M. G. Pamper,
R. L. Wahl and R. F. Dannals. 471
Labelled compounds of interest as antitumour agents-VIII. Synthesis of
^H-isotopomers of pentamethylmelamine and of a potential prodrug thereof
S. Ferrer, L). P. Naughton and M. D. Threadgill. 479
Rapid microwave-assisted cleavage of methyl phenyl ethers: new method for
synthesizing desmethyl precursors and for removing protecting groups
A. Fredriksson and S. Stone-Elander. 529
ISSUE No. 7
Research Articles
A facile preparation of {2,4,6-''*C)-cyanuric acid under solvent-free conditions
S. P. Patil and D. Padmanahhan. 539
Synthesis of PNU-159548 labelled with '“’C and “H
C Fe lie ini and E. Fontana. 543
Synthesis of ' ^C- and '‘^C-labelled catechol
R. Ji and A. Schaffer. 551
Synthesis of tritium labeled isotopomers of L-tyrosine
W. Augustyniak, P. Suchecki, J. Jemielity, R. Kanski and M. Kahska. 559
Synthesis of 5-[4,5-‘^C2]- and 5-[l,5-‘^C2]aminolevulinic acid
K. lida, S. Tokiwa, T. Ishii and M. Kajiwara. 569
1308 Volume Contents
Synthesis of (± )-6,6-pH(i]dimethyl-l l-nor-A^-tetrahydrocannabivarin-9-carboxylic acid
S. Feng and M. A. ElSohly. 577
Synthesis of [‘®F]-labeled 2'-deoxy-2'-fluoro-5-methyl-l-y9-D-arabinofuranosyluracil
(['*F]-FMAU)
M. M. Alauddin, P. S. Conti and J. D. Fissekis. 583
A short synthesis of ['“^CJ-labelled levamisole and its major metabolite
Cor. G. M. Janssen, J. B. A. Thijssen and W. L. M. Verluyten. 591
Synthesis of [l-''^C]-/j«ra-xylene and [2-''^C]-/7ara-xylene
M. Mormann and D. Kuck. 601
Synthesis of stable isotopically labelled versions of lamotrigine and its methylated
metabolite
C. O. Manning, A. H. Wadsworth and I. Fellows. 611
Stereoselective synthesis of l-[2,3,4,5-D4] ornithine
M. Oha, T. Ishihara, H. Satake and K. Nishiyama. 619
ISSUE No. 8
Research Articles
Synthesis of hydroxyl silylated rhenium and (^^'"Tcjtechnetium ‘3+1’ mixed ligand
complexes
T. Kniess, H. Spies, I. Santos and A. Zablotska. 629
Synthesis of doubly ’^C-labelled antalarmin isotopomers for pharmacokinetic studies
E. Greiner, A. J. Atkinson Jr., A. Ayala, G. P. Chrousos, C. Contoreggi,
W. C. Eckelman, P. W. Gold, K. E. Hahih, A. E. Jacobson, N. Whittaker,
E. L. Webster and K. C. Rice. 637
Synthesis and "C-labelling of (£,£■)-l-(3',4'-dihydroxystyryl)-4-(3'-methoxy-4'-
hydroxystyryl) benzene for PET imaging of amyloid deposits
Y. Wang, C. A. Mathis, G. Huang, D. P. Holt, M. L. Debnath and W. E. Khmk. 647
Exchange radioiodination produces inversion at C-4 of l-(4-deoxy-4-iodo-/i-D-
xylopyranosyl)-2-nitroimidazole
R. F. Schneider, W. A. Price and J. D. Chapman. 665
Kidney uptake of '*^^’**Re(V)-DMSA is significantly reduced when the reducing agent
is changed from stannous ion to metabisulfite
K. Kothari, D. Satpati, A. Mukherjee, H. D. Sarnia, M. Venkate.sh and M. R. A. Pillai.. 675
Synthesis of 3-[[4-(4-['**F]fluorophenyl)piperazin-l-yl]methyl]-l//-pyrrolo[2,3-b]pyridine
O. Eskola, J. Bergman, P. Lehikoinen, M. Haaparanta, T. Gronroos, S. Forsback
and O. Solin. 687
Synthesis of 4-dihydroxyboryl-2-['*F]fluorophenylalanine with relatively high-specific
activity
J. K. Vdhdtalo, O. Eskola, J. Bergman, S. Forsback, P. Lehikoinen, J. Jddskeldinen
and O. Solin. 697
Volume Contents 1309
Biographical Memoir
Alfred P. Wolf — A Biographical Memoir
J. S. Fowler and M. J. Welch. 705
ISSUE No. 9
Review Article
Microwave applications in radiolabelling with short-lived positron-emitting
radionuclides
S. Stone-Blander and N. Blander. 715
Research Articles
Synthesis of ['“^C]- and p^S]-labelled PI-88 for pharmacokinetic and tissue distribution
studies
V. Ferro, C. Li, B. Wang, K. Fewings, A. R. King, B. Hammond and B. R. Creese. 747
Improved synthesis of and “H3-salmeterol by Cs2C03-mediated
monoalkylation of a primary amine
T. F. Molinski and S. D. Stanley . 755
Radiosynthesis of l-(4-(2-['^F]fluoroethoxy)benzenesulfonyl)-3-butyl urea: a potential
(3-cell imaging agent
R. Schirrmacher, M. Weber, A. Schmitz, C-Y. Shiue, A. A. Alavi, P. Feilen,
S. Schneider, P. Kann and F. Rosch. 763
Synthesis of ’^N and '"^C selectively labeled anandamide
X-Q. Xie, H. Yang, G. Choi, S. Lin and A. Makriyannis. 775
Synthesis of covalent ['"'CJ-labeled diarylsulfonylurea (DASU) inhibitors of the
processing and release of IL-1
J. F. Bggler, C. A. Gabel, K. Zandi, J. D. Weaver, H. McKechney, M. A. Dombroski,
H. Peurano and N. Hawryluk. 785
Synthesis and mass spectra of labelled 4(5)-nitro-lH-imidazole-5(4)-carbonitriles
J. Suwihski and K. Swierczek . 795
ISSUE No. 10
Review Article
From chiral bromo['^’‘‘*C„]acetyl sultams to complex molecules singly/multiply labelled
with isotopic carbon
R. Voges. 867
Research Articles
Efficient synthesis and formulation of (/?)-(- )-[’'C]Deprenyl, a selective radioligand
for the quantification of MAO-B activity using PET
F Dolle, Y. Bramoulle, F. Hinnen and J. S. Fowler. 803
Synthesis of a '-^C labeled A-cyclopropylamine tetrahydropyridine derivative
5. Kuttab and S. Mabic. 813
1310 Volume Contents
Synthesis of [3'-'‘*C] coenzyme Q,o
K. Hamamura, /. Yamatsu, N. Minami, Y. Yamagishi, Y. Inai, S. Kijima and
T. Nakamura. 823
Synthesis of deuterium-labelled coenzyme Q|o
K. Hamamura, Y. Yamagishi, S. Kijima, T. Suzuki, Y. Mori and T. Nakamura. 831
Synthesis of ^H-, and stable-isotope-labelled galantamine
Cor. G. M. Janssen, J. B. A. Thijssen and W. L. M. Verluyten. 841
Synthesis and preliminary PET study of the S-HTj receptor antagonist ["C]DR4446
M.-R. Zhang, T. Haradahira, J. Maeda, T. Okauchi, T. Kida, S. Ohaya,shi, K. Suzuki
and T. Sahara. 857
ISSUE No. 11
Research Articles
Synthesis of Brostallicin (PNU-166196A) Labelled with and '"’C
E. Fontana and A. Pignatti. 899
Synthesis of tritium labelled zaleplon
V. P. Shevchenko, /. Y. Nagaev, N. F. Myasoedov and A. Susan. 911
The first synthesis of all possible isotopically labelled [D, '-^C] methyl group
combinations of 2,2-dimethyl tetralone
G. S. Coumbarides, J. Fames and N. Weerasooriya. 917
Increased selectivity in inflammatory site identification via labelling of IgG with
yV-succinimidyl-4-[’^^I]iodobenzoate
D. Beiki, S. Shahhosseini, A. Khalaj and M. Eftekhari. 927
The synthesis and characterization of 2-Trideuteriomethyl and 2,2-Di(trideuteriomethyl)
Aryl Ketones
G. S. Coumbarides, J. Fames and N. Weerasooriya. 935
New and convenient synthesis of a tritiated photoactivatable nicotinic agonist: ['^HJ-ACS
A. Mourot, F. Kotzyba-Hibert, E. Doris and M. Goeldner. 943
Synthesis of [''C] A-(2-chloro-5-thiomethylphenyl)-A'-(3-methoxyphenyl)-A'-
methylguanidine (["C]GMOM): a candidate PET tracer for imaging the PCP site of
the NMDA ion channel
R. N. Waterhouse, F. Dumont, A. Sultana, N. Simpson and M. Laruelle. 955
Investigations into the regioselective C-deuteriation of enolates using a diisopropyl-
ammonium salt
G. S. Coumbarides, J. Fames and N. Weerasooriya. 965
Design and synthesis of fluorine-18 labeled matrix metalloproteinase inhibitors for
cancer imaging
S. Furumoto, R. Iwata and T. Ido. 975
Synthesis of radio-iodinated melatonergic agents
D. D. Dischino, R. J. Mattson, M. D. Ogan, M. F. Parker and J. P. Yevich. 987
Volume Contents 1311
ISSUE No. 12
Review Article
Computer simulation tools as applied to radioisotope production target design
C W. A Ivord. 995
Research Articles
Preparation of '*0-labelled nicotinamide
M. Kolodziejska-Huben, Z. Kaminski and P. Paneth. 1005
Radiosynthesis of [‘^^l]yV-(3-iodoprop-{2£)-enyl)-2a-(imino-methyl)-3P-
(3',4'-dichlorophenyl) nortropane as a potential SPET tracer for dopamine transporter
M Yu, A. J. Airaksinen, A. D. Gee, S. Lotjonen, J. T. Kuikka, J. J. Vepsdldinen,
J. Hiltunen and K. A. Bergstrom. 1011
New preparation of ['^^I]PE2I: investigation of the oxidation and purification steps
E. Berthommier, C. Lot ’ll, S. Chalon, C. Olivier, P. Emond, H. Dao Boulanger,
M. A. Lelait and L. Mauclaire. 1019
Preparation, characterization and biodistribution of a new technetium-99 m nitrido
complex with 2-methoxyisobutylisonitrile and comparison with ^‘^"’Tc-MIBI
A'. Zh. Zhang, X. B. Wang, F. Jia, Z. G. Tang, J. B. Zhang, B. L Liu and X. Y. Wang ... 1029
Hydroacylation of 4-['*F]fluorobenzaldehyde: a novel method for the preparation of
4'-[' *^F]phenylketones
N.-U. H. Khan, B. C. Lee, S.-Y. Lee, Y. S. Choe, C.-H. Jim and D. Y. Chi. 1045
Syntheses of stable-isotope labeled [M + 7] and [M + 6] 2-(methylamino)imidazole
Y. Zhang. 1055
Synthesis of side chain specifically deuterated (- )-A^-tetrahydrocannabinols
S. P. Nikas, G. A. Thakur and A. Makriyannis. 1065
Preparation of the iodine-124 derivative of the Bolton-Hunter reagent (['““^IJl-SHPP)
and its use for labelling a VEGF antibody as a PET tracer
M. O. Glaser, V. A. Carroll, D. R. Collingridge, E. O. Ahoagye, P. Price, R. Bicknell,
A. L. Harris, S. K. Luthra and F. Brady. 1077
ISSUE No. 13
Research Articles
Critical evaluation of the chemical standardization procedure for measuring gastric
emptying of solids
P. Goethals, A. Volkaert, B. Van Vlem and R. Vanholder. 1091
Synthesis of '^^P-labeled intermediates on the purine biosynthetic pathway
R. A. Me hi and T. P. Begley. 1097
Ort/?u-['^F]Fluoronitrobenzenes by no-carrier-added nucleophilic aromatic substitution
with K['*F]F — K222—A comparative study
M. Karramkan, F. Hinnen, Y. Bramoulle, S. Juheau and F. Dolle. 1103
Synthesis of [’“^Cj-labelled repinotan hydrochloride and its major metabolite M-6
D. Seidel, M. Conrad, Y. Schoof and R. Schohe-Loop. 1115
1312 Volume Contents
Synthesis of (±) [5-'^H] A^'-nitrosoanatabine, a tobacco-specific nitrosamine
D. Desai, G. Lin, H. Morimoto, P. G. Williams, K. El-Bayoumy and S. Amin. 1133
Synthesis of '"‘C-labeled 4-hydroxyindole as an intermediate for the preparation of
(5)-2-[4-[2-[3-(indol-2-[*'*C]-4-yloxy)-2-hydroxypropylamino]-2-methylpropyl]-
phenoxy]pryridine-5-carboxamide(LY368842-[indole-*"^C]) glycolate
B. A. Czeskis, D. K. Clodfelter and W. J. Wheeler. 1143
Synthesis of [^H^j-dextromethorphan and its major urinary metabolites
[^H3]-dextrorphan and [^H^J-dextrorphan-Z^-glucuronide
G. Heinkele, G. Schdnzle and T. E. Miirdter. 1153
Abstracts
lOth Conference of the Central European Division e.V. of the International Isotope
Society, Bad Soden, Germany, 6-7 June 2002
Selected abstracts
R. Voges and U. Pleiss. 1159
ISSUE No. 14
Research Articles
Fully automated high yield synthesis of (/?)- and (S)-["C]verapamil for measuring
P-glycoprotein function with positron emission tomography
G. Luurtsema, A. D. Windhorst, M. P. J. Mooijer, J. D. M. Herscheid,
A. A. Lammertsma and E. J. F. Franssen. 1199
Isotopic labeling of 2-desoxoparaherquamide A (PNU-141962) with deuterium
B. H. Lee. 1209
Synthesis of '^F labelled FK960, a candidate anti-dementia drug, and PET studies in
conscious monkeys
Y. Murakami, S. Nishimura, A. Noda, N. Harada and H. Tsukada . 1219
Reaction of ['^F]4-fluorobenzenediazonium cations with cysteine or the cysteinyl
group: preparation of '*F-labeled S-aryl-cysteine and a radiolabeled peptide
J. T. Patt and M. Patt . 1229
Synthesis of radiolabeled O^-benzylguanine derivatives as new potential PET tumor
imaging agents for the DNA repair protein O^-alkylguanine-DNA alkyltransferase
Q. -H. Zheng, X. Liu, X. Fei, J.-Q. Wang, D. W. Ohannesian, L. C. Erickson,
K. L. Stone, T. D. Martinez, K. D. Miller and G. D. Hutchins . 1239
Synthesis of tertiary '"*C-labelled nonylphenol isomers
R. Vinken, B. Schmidt and A. Schaffer . 1253
An improved synthesis of [phenyl-’'*C(U)] Lawsone
C Wright and G. V. Vilas. 1265
Cumulative Compound Index (October 2001-August 2002). 1269
Keyword Index. 1295
Author Index. 1299
Volume Contents. 1303