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CODEN JINMEO _ ISSN 0954-6820 Volume 245 1999 Journal of INTERNAL MEDICINE VOLUME CONTENTS Editor: G. Holm Associate Editors: B. Angelin U. de Faire B. Fagrell S. Ljunghall S S s eS Blackwell Science Published by Blackwell Science Editorial Offices: Blackwell Science Ltd 23 Ainslie Place, Edinburgh EH3 6AJ, UK Blackwell Science Ltd 25 John Street, London WC1N 2BL, UK Blackwell Science Ltd Osney Mead, Oxford OX2 OEL, UK Blackwell Science Asia Ltd 54 University Street, (PO Box 378), Carlton South, Victoria 3053, Australia Blackwell Science Europe Ltd 10 rue Casimir Delavigne, F-75006 Paris, France Blackwell Wissenschafts Verlag GmbH Kurfiirstendamm 57, D-10707 Berlin, Germany Blackwell Science KK MG Kodenmacho Building, 7-10 Kodenmacho Nihombashi, Chuo-ku, Tokyo 104, Japan Blackwell Science Inc. Suite 500, 5th Floor, 238 Main Street, Cambridge, MA 012142, USA © 1999 Blackwell Science Ltd. Authorization to photocopy for internal or personal use or the internal or personal use of specific clients is granted by Blackwell Science Ltd for libraries and other users registered with the Copyright Clearance Center (CCC) Transactional Reporting Service, provided that the base fee of $14.00 per copy is paid directly to the CCC, 222 Rosewood Drive, Suite 910, Danvers, MA 01923, USA. This consent does not extend to other kinds of copying, such as copying for general distribution for advertising or promotional purposes, for creating new collective works or for resale. Special requests should be addressed to the Editor. 0954-6820; $14.00. The Blackwell Science logo is a trade mark of Blackwell Science Ltd registered at the United Kingdom Trade Marks Registry. VOLUME CONTENTS NO. 1, JANUARY A. Ivarsson, L. A. Persson, P. Juto, M. Peltonen, O. Suhr & O. Hernell EDITORIAL The effect of clinical trials on treatment in Hypocalcaemia in HIV infection and AIDS myocardial infarction E. W. Kuehn, H. J. Anders, J. R. Bogner, L. Wilhelmsen ]. Obermaier, E Goebel& D. Schléndorff REVIEW Fibrinogen and mortality in chronic critical Breast cellulitis complicating breast limb ischaemia conservation therapy R. Pedrinelli, M. Mariani, G. Dell’ Omo, L. M. Baddour A. Barchielli, R. Berchiolli, E. Melillo, M. Mariani, A. Balbarini & M. Ferrari ORIGINAL ARTICLES The response to inhaled and oral steroids in Trends in the treatment of patients with patients with stable chronic obstructive myocardial infarction and coronary pulmonary disease revascularization procedures in Finland, P. Weiner, M. Weiner, M. Rabner, J. Waizman, 1986-1992. The FINMONICA Myocardial R. Magadle & D. Zamir Infarction Register Study H. Miettinen, V. Salomaa, M. Ketonen, M. Niemeld, P Immonen-Rdiha & M. Mahonen Intestinal endocrine cells in myotonic dystrophy: an immunocytochemical and computed image analytical study Antiplasmin correlates to arterial reactivity in a A. Rénnblom, A. Danielsson & M. El-Salhy healthy population of 35-year-old men and women J. Johansson, K. Jensen-Ursta&d Low vitamin E status is a potential risk factor M. Jensen-Urstad for insulin-dependent diabetes mellitus P. Knekt, A. Reunanen, ]. Marniemi, A. Leino Hereditary haemorrhagic telangiectasia: a é A. Aromaa population-based study of prevalence and mortality in Danish patients CASE REPORT A. D. Kjeldsen, P. Vase & A. Green Sickle cell-like crisis and bone marrow necrosis associated with parvovirus B19 infection and The snack is critical for the blood glucose profile heterozygosity for haemoglobins S and E during treatment with regular insulin R. E. Eichhorn, E. J. Buurke, P. Blok, preprandially M. J. H. Berends & C. L. Jansen A.-C. Orre-Pettersson, T. Lindstrém, V. Bergmark & H. J. Arnqvist LETTER TO THE EDITOR Atorvastatin compared to simvastatin in Hepatitis C virus transmission following patients with severe LDL invasive medical procedures hypercholesterolaemia treated by regular LDL ]. Delwaide, C. Gérard, D. Vaira, G. Maggipinto, apheresis B. Rentier & J. Belaiche H. C. Geiss, K. G. Parhofer & P. Schwandt INSTRUCTIONS TO AUTHORS Decreased heart rate variability in patients with type I diabetes mellitus is related to arterial wall stiffness K. Jensen-Urstad, P. Reichard& NO. 2, FEBRUARY M. Jensen-Urstad REVIEW The high prevalence of undiagnosed coeliac disease in adults: a Swedish population-based Nephropathy in type 2 diabetes study E. Ritz © 1999 Blackwell Science Ltd Journal of Internal Medicine VOLUME CONTENTS ORIGINAL ARTICLES due to postpartum autoimmune myocarditis. A report of three cases 199 Extrahepatic manifestations of chronic A. Yagoro, H. Tada, Y. Hidaka, Y. Ohnishi, hepatitis C infection and the interrelationship S. Nagata, H. Sato & N. Amino between primary Sjégren’s syndrome and hepatitis C in Swedish patients H. Verbaan, J. Carlson, S. Eriksson, A. Larsson, R. Liedholm, R. Manthorpe, H. Tabery, A. Widell & S. Lindgren NO. 3, MARCH A comparison of metoprolol and morphine in REVIEW the treatment of chest pain in patients with suspected acute myocardial infarction: the Asthma and leukotrienes: antileukotrienes as MEMO Study novel antiasthmatic drugs B. Everts, B. Karlson, N.-]. Abdon, J. Herlitz & H.-E. Claesson & S.-E. Dahlén T. Hedner ORIGINAL ARTICLES Factors associated with the use of various Bedtime uncooked cornstarch supplement medications amongst patients with severe prevents nocturnal hypoglycaemia in coronary artery disease intensively treated type 1 diabetes subjects J. Herlitz, B. Brorsson & L. Werko for the M. Axelsen, C. Wesslau, P. Lénnroth, SECOR/SBU Project Group R. Arvidsson Lenner & U. Smith Factors predicting clinical remission in adult Musculo-skeletal pathology in patients with patients with type 1 diabetes angina pectoris and normal coronary A. Schélin, C. Berne, E. Schvarcz, E. A. Karlsson & E. Bjork angiograms O. Frobert, J. Fossgreen, J. Sondergaard-Petersen, J. Hede & J. P. Bagger Prevalence of the metabolic syndrome in drug- treated hypertensive patients and control subjects Studies in hypertriglyceridaemia VI: serum A. O. Rantala, H. Kauma, M. Lilja, lathosterol concentration is raised in M. J. Savolainen, A. Reunanen & hypertriglyceridaemic non-diabetic males Y. A. Kesadniemi with hyperinsulinaemia A. Asplund-Carlson, E. Lund, I. Bjérkhem & L. A. Carlson Effect of folic acid and betaine on fasting and postmethionine-loading plasma homocysteine and methionine levels in The different effects of a Gin27Glu chronic haemodialysis patients 8,-adrenoceptor gene polymorphism on C. van Guldener, M. J. E M. Janssen, K. de Meer, obesity in males and females A. J. M. Donker& C. D. A. Stehouwer L. Hellstrom, V. Large, S. Reynisdottir, H. Wahrenberg & P. Arner Relative importance of improved hospital treatment and primary prevention. Results Post-streptococcal reactive arthritis: a clinical from 20 years of the Myocardial Infarction and serological description, revealing its Register, Goteborg, Sweden distinction from acute rheumatic fever L. Wilhelmsen, A. Rosengren & G. Lappas T. L. Th. A. Jansen, M. Janssen, A. J. L. de Jong & M. E. C. Jeurissen Effects of diabetes mellitus on patients with acute intermittent porphyria Cross-sectionally assessed carotid intima—media C. Andersson, I. Bylesjé & E Lithner thickness relates to long-term risk of stroke, coronary heart disease and death as CASE REPORT estimated by available risk functions M. L. Bots, A. W. Hoes, A. Hofman, Postpartum onset of acute heart failure possibly J. C. M. Witteman & D. E. Grobbee © 1999 Blackwell Science Ltd Journal of Internal Medicine VOLUME CONTENTS Autoimmunity and extranodal lymphocytic ORIGINAL ARTICLES infiltrates in lymphoproliferative disorders Urinary albumin excretion rate is independently V. Jonsson, A. Wiik, K. Hou-Jensen, related to autonomic neuropathy in type 2 M. Christiansen, L. P. Ryder, H. O. Madsen, diabetes mellitus C. Geisler, M. M. Hansen, K. Thomsen, O. R. Wirta, A. I. Pasternack, J. T. Mustonen, S. Vorstrup & A. Svejgaard P. J. Laippala & P. M. Reinikainen Parasympathetic function during deep Under-reporting of dietary intake by smoking breathing in the general population: relation and non-smoking subjects counselled for to coronary risk factors and normal range hypercholesterolaemia O. May, H. Arildsen & M. Moller S. Tonstad, C. Gerbitz, M. Sivertsen & L. Ose Aetiology and clinical significance of Adrenal steroid dysregulation in dystrophia thrombocytosis: analysis of 732 patients with myotonica an elevated platelet count A. Johansson, A. Henriksson, B.-O. Olofsson & T. M. Griesshammer, M. Bangerter, T. Sauer, Olsson R. Wennauer, L. Bergmann & H. Heimpel 3ronchoalveolar lavage cells from sarcoidosis CASE REPORTS patients and healthy controls can efficiently Cutaneous necrosis as a terminal present antigens paraneoplastic thromboembolic event in a J. Grunewald, A. Eklund, H. Wigzell, K. E. van patient with non-Hodgkin's lymphoma Meijgaarden & T. H. M. Ottenhoff J. Luboshitz, O. Bairey, D. Blickstein, H. Vaknin, E. Okon, J. Lahav & M. Prokocimer OT dispersion and late potentials during doxorubicin therapy for non-Hodgkin's Life-threatening ventricular tachycardia due to lymphoma liquorice-induced hypokalaemia T. Nousiainen, E. Vanninen, A. Rantala, E. Jantunen & J. Hartikainen J. W. Eriksson, B. Carlberg & V. Hillérn MINISYMPOSIUM: ORAL ANTICOAGULATION — LETTERS TO THE EDITOR HOW INTENSE AND FOR HOW LONG? Use and misuse of atherosclerosis W. E. Stehbens Introduction S. Schulman Metabolic abnormalities related to cardiovascular risk in primary hyperparathyroidism: effects of surgical Oral anticoagulant treatment in patients with mechanical heart valves: how to reduce the treatment I. Barna, A. Varadi & P. Lakatos risk of thromboembolic and bleeding complications S. C. Cannegieter, M. Torn & FE. R. Rosendaal Reply S. Valdemarsson, P. Lindblom, A. Bergenfelz Oral anticoagulation in non-valvular atrial fibrillation B. G. Koefoe&d P. Petersen NO. 4, APRIL Oral anticoagulations are effective long term after acute myocardial infarction REVIEW P. Smith Clinical importance of coronary endothelial vasodilator dysfunction and therapeutic Oral anticoagulation in peripheral vascular options surgery: how intense, for how long, at all? M. B. Britten, A. M. Zeiher & V. Schachinger G. Kretschmer & T. Hoélzenbein © 1999 Blackwell Science Ltd Journal of Internal Medicine VOLUME CONTENTS Oral anticoagulation in venous Insulin-like growth factor-I lowers fasting and thromboembolism: decisions based on more postprandial triglyceride levels without affecting than mere feelings chylomicron clearance in healthy men S. Schulman T. Bianda, J. Zapf, E. R. Froesch & C. Schmid CASE REPORT The survival and well-being of patients treated Relapsing pneumonia due to a migrating for Cushing’s syndrome intrathoracic foreign body in a World War II L. Pikkarainen, T. Sane & A. Reunanen veteran shot 53 years ago 405 D. Langer, C. Petermann, H. Ltibbers & P. G. Colonic endocrine cells in patients with familial Lankisch amyloidotic polyneuropathy I. Anan, M. El-Salhy, Y. Ando, N. Nyhlin, LETTERS TO THE EDITOR H. Terazaki, N. Sakashita & O. Suhr Cortisol deficiency may account for elevated apoptotic cell population in patients with Impaired granulocyte formylpeptide-induced chronic fatigue syndrome superoxide generation in chronically ill, R. Baschetti malnourished, elderly patients T. Cederholm & H. Gyllenhammar Single aetiologic agent may not be feasible in CFS patients 410 A. Vojdani Streptokinase antibodies inhibit reperfusion during thrombolytic therapy with ERRATUM streptokinase in acute myocardial infarction P. Juhlin, P-A. Bostrom, A. Torp& A. Bredberg Intestinal endocrine cells in myotonic dystrophy: an immunocytochemical and computed image analytical study 413 Lean mass and physical activity as predictors of A. Rénnblom, A. Danielsson & M. El-Salhy bone mineral density in 16—20-year old women O. Valdimarsson, J. O. Kristinsson, S. O. Stefansson, S. Valdimarsson & G. Sigurdsson NO. 5, MAY Panic disorder in chest pain patients referred for cardiological outpatient investigation ORIGINAL ARTICLES T. Dammen, H. Arnesen, QO. Ekeberg, T. Husebye & S. Friis Relationship between serum ferritin and risk factors for ischaemic heart disease in 2235 Danes aged 30—60 years Relationships between bone mineral density, N. Milman& M. Kirchhoff serum vitamin D metabolites and calcium : phosphorus intake in healthy perimenopausal women The circulating renin—angiotensin system during treatment with metoprolol or captopril in C. Brot, N. Jargensen, O. R. Madsen, L. B. Jensen patients with heart failure due to non- & O. H. Sorensen ischaemic dilated cardiomyopathy K. Jansson, U. Dahlstrém, B. E. Karlberg, The spectrum of hepatobiliary disease in primary E. Karlsson, E. Nylander, O. Nyquist & hypogammaglobulinaemia K.-E. Karlberg K. Bjero, T. Haaland, K. Skaug & S. S. Freland Improvement in quality of life differs between women and men after coronary artery bypass Evidence of gastrointestinal immune reactivity in surgery 445 patients with sarcoidosis H. Sjéland, I. Wiklund, K. Caidahl, M. Hartford, K. I. Papadopoulos, K. Sjoberg, S. Lindgren & T. Karlsson & J. Herlitz B. Hallengren © 1999 Blackwell Science Ltd Journal of Internal Medicine VOLUME CONTENTS Plasma leptin levels are associated with P-O. Hansson, E. Eriksson, L. Welin & abnormal fibrinolysis in men and H. Eriksson postmenopausal women 533 S. Sdéderberg, T. Olsson, M. Eliasson, O. Johnson & Pulmonary embolism: a follow-up study of the B. Ahrén relation between the degree of right ventricle overload and the extent of perfusion defects 60] Significance of graft occlusion and coronary A. Ribeiro, P. Lindmarker, H. Johnsson, atherosclerosis 5 years after coronary artery A. Juhlin-Dannfelt & L. Jorfeldt bypass grafting. A quantitative angiographic study with serial exercise testing MINISYMPOSIUM K. Korpilahti, E. Engblom, H. Hamdildinen, Genes and obesity M. Syvanne, E. Hietanen, M. Arstila, PR. Puukka & T. Ronnemaa Contents 611] Genes involved in animal models of obesity and ERRATUM anorexia 613 M. Schalling, J. Johansen, L. Nordfors & Munchausen syndrome E Lonngqvist J] Intern Med 1998; 244: 543-545 T. O. Cheng The role of TNFa and TNF receptors in obesity and insulin resistance 621 G. S. Hotamisligil NO. 6, JUNE Genetically engineered mice in drug development 627 ORIGINAL ARTICLES J. N. Livingston Short stature and prognosis of coronary heart Contributions of studies on uncoupling proteins disease in women to research on metabolic diseases 637 S. P Wamala, M. A. Mittleman, M. Horsten, D. Ricquier, C. Fleury, M. Larose, D. Sanchis, K. Schenck-Gustafsson & K. Orth-Gomér C. Pecqueur, S. Raimbault, C. Gelly, D. Vacher, A.-M. Cassard-Doulcier, C. Lévi-Meyrueis, Comparison of secondary prevention measures O. Champigny, B. Miroux & E Bouillard after myocardial infarction in subjects with and without diabetes mellitus Leptin and its potential role in human obesity 643 T. A. Chowdhury, S. S. Lasker & P. H. Dyer E Lénnqvist, L. Nordfors & M. Schalling Ethical aspects of clinical trials: the attitudes of Genetics of human obesity: lessons from mouse the public and out-patients models and candidate genes 653 S. Madsen, §. Holm & P. Riis S. M. Echwald Habitual dietary intake versus glucose tolerance, Adrenoceptor genes in human obesity insulin sensitivity and insulin secretion in P. Arner & J. Hoffstedt postmenopausal women H. Larsson, S. Elmstahl, G. Berglun&d B. Ahrén AUTHOR INDEX Prevalence of APC resistance and its relationship KEYWORD INDEX to arterial and venous thromboembolism in a general population sample of elderly Swedish men: The Study of Men Born in 1913 VOLUME CONTENTS 1999 Blackwell Science Ltd Journal of Internal Medicine