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Volume 230 1991 Journal of INTERNAL MEDICINE Editor: L. E. Bottiger Blackwell Scientific Publications © Blackwell Scientific Publications Ltd Copyright. © 1991 Blackwell Scientific Publications Ltd. Authorization to photocopy for internal use or the internal or personal use of specific clients is granted by Blackwell Scientific Publications Ltd for libraries and other users registered with the Copyright Clearance Center (CCC) Transactional Reporting Service, provided that the base fee of $05.00 per copy is paid directly to the CCC, 27 Congress Street, Salem, MA 01970, USA. This consent does not extend to other kinds of copying, such as copying for general distribution for advertising or promotional purposes, for creating new collective works or for resale. Special requests should be addressed to the Editor. 0954-6820/91 $05.00. ISSN 0954-6820 Contents VOLUME 230 NO. 1 JULY 1991 EDITORIAL Do we know what we are doing? Coffee, coronary heart disease and mortality in L. Werk6é middle-aged Swedish men: findings from the Primary Prevention Study A. Rosengren & L. Wilhelmsen ORIGINAL ARTICLES CASE REPORTS Risk factors for benign oesophageal disease in Unusual clinical presentation of malignant a random population sample histiocytosis in a 70-year-old woman I. I. Andersen & G. Jensen M. Komatsu, M. Katakura, T. Aizawa, Pathogenetic mechanism of stroke in Y. Yukimura, T. Yamada, H. Saito, S. Furuta, non-valvular atrial fibrillation: follow-up N. Ito & Y. Onishi of stroke patients with and without atrial Reversible hypertriiodothyroninaemia due to fibrillation adrenal insufficiency C. Gustafsson & M. Britton R. Comtois, J. Hébert & J.-P. Soucy Cardiovascular risk factors in young L-tryptophan-induced eosinophilia-myalgia snuff-users and cigarette smokers syndrome M. Eliasson, D. Lundblad & E. Hagg P. J. Arnouts, L. J. Colemont, M. J. Van Outryve Lovastatin therapy in heterozygous familial & E. M. Van Moer hypercholesterolaemic patients: effect on Cimetidine and ranitidine may not cross-react blood rheology and fibrinogen levels to cause thrombocytopenia Y. Beigel, J. Fuchs, M. Snir, Y. Lurie, P. Green O. Shalev & D. Seror & M. Djaldetti Cardiovascular risk factors in primary CORRESPONDENCE hyperparathyroidism: a 15-year follow-up of operated and unoperated cases HTLV-1 associated myelopathy combined with L. Lind, S. Jacobsson, M. Palmer, H. Lithell, chronic thyroiditis 89 B. Wengle & S. Ljunghall T. Fukuzawa, T. Hamada, K. Hamada, T. Yanagihara, Abnormal tubular handling of sodium and K. Tashiro & F. Morikawa water induced by atrial natriuretic peptide GM-CSF for agranulocytosis 90 in essential hypertension A. Gerl, H. Gerhartz & W. Wilmanns H. Eiskjer, J. D. Jensen, B. Jespersen, INSTRUCTIONS TO AUTHORS 93 S. S. Serensen & E. P. Pederson Early postoperative basal serum GH level and the GH response to TRH in relation to the long-term outcome of surgical treatment for VOLUME 230 NO. 2 AUGUST 1991 acromegaly: a report on 39 patients S. Valdemarsson, M. Bramnert, S. Cronquist, EDITORIAL A. Elner, C. M. Eneroth, P. Hedner, Internal medicine and molecular biology — M. Lindvall-Axelsson, C. H. Nordstrém molecular medicine & L. G. Strémblad P. Bjérntorp, J. Nilsson & G. Holm Coronary artery vasoregulation and left ventricular function in patients with angina pectoris-like pain and normal coronary ORIGINAL ARTICLES angiograms B. Lagerqvist, H. Bylund, P. Gétell, Intensified conventional insulin treatment F. Mannting, B. Sandhagen & A. Waldenstrém retards the microvascular complications of insulin-dependent diabetes mellitus (IDDM): CASE REPORTS the Stockholm Diabetes Intervention Study Successful treatment of hepatosplenic (SDIS) after 5 years candidiasis with a liposomal amphotericin B P. Reichard, B. Berglund, A. Britz, I. Cars, preparation B. Y. Nilsson & U. Rosengqvist M. Bjérkholm, N. Kallberg, G. Grimfors, Thalassaemia trait and myocardial infarction: L. H. Eklund, S. Eksborg, O. T. Juneskans low infarction incidence in male subjects & A.-M. Uden confirmed Adrenocortical insufficiency with normal M. Gallerani, C. Scapolis, I. Cicognani, A. Ricci, serum cortisol levels and hyporeninaemia in L. Martinelli, R. Cappato, R. Manfredini, a patient with acquired immunodeficiency G. Dall'ara, M. Faggioli & P. L. Pareschi syndrome (AIDS) Sinemet (CR4): an open-label study in R. Cobbs, G. M. Pepper, J. G. Torres moderately severe Parkinson’s disease & H. L. Gruenspan A. Ming, J. A. Temlett & V. U. Fritz Expression of type III hyperlipoproteinaemia in Excess mortality in giant cell arteritis a subject with secondary hypothyroidism C. Bisgard, H. Sloth, N. Keiding & K. Juel bearing the apolipoprotein E2/2 phenotype Obstructive sleep apnoea syndrome in G. Feussner & R. Ziegler morbidly obese patients Nephrocalcinosis in Sj6gren’s syndrome: a late R. Rajala, M. Partinen, T. Sane, R. Pelkonen, sequela of renal tubular acidosis K. Huikuri & A.-M. Seppdaldinen H. M. Moutsopoulos, J. Cledes, F. N. Skopouli, Serum lipid and apolipoprotein levels in M. Elisaf& P. Youinou non-hypertensive lean NIDDM patients T. Ikeda, H. Ochi, I. Ohtani, K. Fujiyama, T. Hoshino, Y. Tanaka, T. Takeuchi & H. Mashiba The sleep apnoea syndrome in obesity: risk of sudden death S. Réssner, L. Lagerstrand, H. E. Persson VOLUME 230 NO. 3 SEPTEMBER 1991 & C. Sachs Increased occurrence of arrhythmias in men EDITORIAL with ischaemic type ST-segment depression during long-term ECG recording. Prognostic Finnish amyloidosis: from protein to gene impact on ischaemic heart disease: results C. P. J. Maury from the prospective population study ‘Men born in 1914’, Malm6, Sweden S. Juul-Moéller, B. Hedblad, L. Janzon & B. W. Johansson HYPOTHESIS Long-term effects of simvastatin in familial Visceral fat accumulation: the missing link dysbetalipoproteinaemia between psychosocial factors and P. M. J. Stuyt, M. J. T. M. Mol cardiovascular disease? & A. F. H. Stalenhoef P. Bjérntorp Evaluation of a structured treatment and teaching programme on asthma I. Mihlhauser, B. Richter, D. Kraut, G. Weske, H. Worth & M. Berger Characteristics of cirrhosis undiagnosed during ORIGINAL ARTICLES life: a comparative analysis of 73 Non-invasive evaluation of long-term cardiac undiagnosed cases and 149 diagnosed cases effects of captopril in systemic sclerosis 203 of cirrhosis, detected in 4929 consecutive E. Kazzam, K. Caidahl, R. Hallgren, autopsies R. Gustafsson & A. Waldenstrém N. Graudal, P. Leth, L. Marbjerg Hand-free stethoscope — method and & A. M. Galloe instrument for more reliable blood pressure measurements 2a3 P. Ljungvall & T. Thulin Antihypertensive efficacy and tolerability of VOLUME 230 NO. 4 OCTOBER 1991 enalapril and slow-release verapamil in essential hypertension: a double-blind, EDITORIAL cross-over study Coffee and cholesterol: what is brewing? B. Fagher, P. Katzman, U. L. Hulthén, D. S. Thelle N. C. Henningsen & T. Thulin Folic acid absorption in patients infected with the human immunodeficiency virus ORIGINAL ARTICLES P. Revell, M. J. O'Doherty, A. Tang & The hypercholesterolaemic factor in boiled G. F. Savidge coffee is retained by a paper filter Long-term prognosis after early intervention I. Ahola, M. Jauhiainen & A. Aro with metoprolol in suspected acute Coffee drinking and blood cholesterol—effects myocardial infarction: experiences from the of brewing method, food intake and life style MIAMI trial B. Lindahl, I. Johansson, F. Huhtasaari, The MIAMI Trial Research Group G. Hallmans & K. Asplund Ionized calcium in blood: studies on patients Cost-benefit analysis of non-pharmacological with pulmonary disease treatment of hypertension S. Vadstrup & J. Wandrup M. Johannesson, H. Aberg, L. Agréus, Sleep difficulties, pain and other correlates L. Borquist & B. Jonsson P. F. Moffitt, E. C. Kalucy, R. S. Kalucy, Serum platelet-derived growth factor and F. E. Baum & R. D. Cooke endothelin concentrations in human Patients admitted to the emergency room with hypercholesterolaemia symptoms indicative of acute myocardial P. M. W. Bath & J. F. Martin infarction Adenosine provokes myocardial ischaemia in B. W. Karlson, J. Herlitz, P. Pettersson, patients with ischaemic heart disease H.-E. Ekvall & A. Hjalmarson without increasing cardiac work Colonic epithelial dysplasia or carcinoma in a E. Straat, P. Henriksson & A. Edlund regional group of patients with ulcerative Increased plasma level of substance P in colitis of more than 15 years duration patients with severe congestive heart failure M. Vilien, M. J. Jorgensen, Q. Ouyang, treated with ACE inhibitors P. Schlichting, J. Linde, P. Riis & V. Binder S. Valdemarsson, L. Edvinsson, R. Ekman, Screening for haemochromatosis: prevalence P. Hedner & A. Sjoholm among Danish blood donors The significance of venography in the P. Wiggers, J. Dalhaj, H. Kier, H. Ring-Larsen, management of patients with clinically P. Hyltoft Petersen, O. Blaabjerg & M. Horder suspected pulmonary embolism Clinical symptoms in young adults with W. H. J. Kruit, A. C. de Boer, A. K. Sing atypical chest pain attending the emergency & F. van Roon department Influence of lovastatin therapy on metabolism M. Roll, M. Kollind & T. Theorell of low density lipoproteins in mixed hyperlipidaemia G. L. Vega & S. M. Grundy CASE REPORTS Intravenous prostacyclin in thrombotic CASE REPORTS thrombocytopenic purpura: case report and review of the literature Severe coagulopathy after a bite from a B. Tardy, Y. Page, C. Comtet, B. Tardy-Poncet, ‘harmless’ snake (Rhabdophis subminiatus) F. Zeni, H. Decousus & J. C. Bertrand R. E. H. Smeets, P. G. Melman, Paraproteinaemia in relatives of patients with J. J. M. L. Hoffmann & A. W. Mulder primary acquired agammaglobulinaemia Extra-adrenal phaeochromocytoma presenting H. Habashi, A. Heppleston & J. Winter as fulminant malignant disease with tumour Isolated cryptococcosis of the adrenal gland positive sputum cytology Yung-Ching Liu, Deh-Lin Cheng, Cheng-Yi Liu, R. S. de Jong, H. A. van den Bergen, Muh-Yong Yen & Ran-Shang Wang C. A. Boender & T. Tjabbes Multiple myeloma and chronic A comparison between nicotinic acid and myelomonocytic leukaemia developing in a acipimox in hypertriglyceridaemia—effects patient with autoimmune disease 361 on serum lipids, lipoproteins, glucose H. M. Habashi, R. A. Sharp & M. J. Pippard tolerance and tolerability P. Tornvall & G. Walldius A 4-year prospective follow-up study of the MINISYMPOSIUM role of alcohol in recurrences of atrial Microdialysis—a technique for the future fibrillation P. Koskinen Microdialysis—a new and promising method Cardiac rehabilitation—a cost analysis in clinical medicine L.-A. Levin, J. Perk & B. Hedbéick P. Lénnroth Cigarette smoking and urinary albumin Microdialysis—principles and applications for excretion in insulin-treated diabetics without studies in animals and man manifest nephropathy U. Ungerstedt G. Ekberg, N. Grefberg & L. O. Larsson Microdialysis sampling of the neuronal Features of Sj6gren’s syndrome in patients environment in basic and clinical research with primary biliary cirrhosis A. Hamberger, I. Jacobson, B. Nystrém P. Uddenfeldt, A. Danielsson, A. Forssell, & M. Sandberg M. Holm & Y. Ostberg Microdialysis of adipose tissue Extensor digitorum brevis in diabetic P. Arner & J. Bolinder neuropathy: a controlled evaluation in diabetic patients aged 15-50 years P. Lithner, T. Bergenheim & B. Borssén Lack of association of migraine with coronary VOLUME 230 NO. 5 NOVEMBER 1991 vasospasm W. Plimi, I. Kommissari, V. Pfaffenrath EDITORIAL & T. von Arnim Non-surgical therapy of gallstone disease—present situation CASE REPORTS U. Leuschner Enhanced neutrophil functions in a patient with colony stimulating activity-producing lung cancer REVIEW ARTICLE A. Ohsaka, S. Kitagawa, K. Ikeda, The polymerase chain reaction and its K. Motoyoshi, Y. Miura, S. Kira & M. Saito potential role in clinical diagnostics and Misoprostol-induced urinary incontinence research V. Fossaluzza, P. di Benedetto, A. Zampa J. Reiss & S. de Vita Rapidly fatal Addison’s disease: three case reports J. Ringstad, S. Rodge, W. Leland & L. Rode ORIGINAL ARTICLES Effect of apolipoprotein E polymorphism and Xbal polymorphism of apolipoprotein B on VOLUME 230 NO. 6 DECEMBER 1991 response to lovastatin treatment in familial EDITORIAL and non-familial hypercholesterolaemia 397 J. P. Ojala, E. Helve, C. Ehnholm, Atherothrombotic mechanisms in smoking K. Aalto-Setala, K. K. Kontula & M. J. Tikkanen K. E. Laustiola Angiotensin-converting enzyme inhibition and physical training in heart failure 407 REVIEW ARTICLE T. E. Meyer, B. Casadei, A. J. S. Coats, P. P. Davey, S. Adamopoulos, A. Radaelli T-cell vaccination in immunological disease & J. Conway I. R. Cohen ORIGINAL ARTICLES Effect of pancreas transplantation on glucose counterregulation in insulin-dependent High coronary mortality in cold regions of diabetic patients prone to severe Sweden hypoglycaemia S. Gyllerup, J. Lanke, L. H. Lindholm & J]. Bolinder, H. Wahrenberg, A. Persson, B. Scherstén B. Linde, G. Tydén, C.-G. Groth & J. Ostman Water hardness does not contribute substantially to high coronary mortality in cold regions of Sweden S. Gyllerup, J. Lanke, L. H. Lindholm & CASE REPORTS B. Scherstén Adrenomyeloneuropathy—report on a family Cardiac left ventricular function before and B. H. Holmberg, E. Hagg & L. Hagenfeldt during early thyroxine treatment in severe Acute fungal thyroiditis in a patient with hypothyroidism acute myelogenous leukaemia R. Bernstein, C. Miiller, K. Midtbe, E. Haug, J. F. Fernandez, E. J. Anaissie, K. F. Nakken, L. Hertzenberg & K. E. Kjorstad R. Vassilopoulou-Sellin & N. A. Samaan The role of paid work in Swedish chronic Diclofenac-induced thrombocytopenic purpura dialysis patients—a nation-wide survey: with renal and hepatic involvement paid work and dialysis J]. Bondeson & S. Berglund S. Theorell, J. K. Konarski-Svensson, J. Ahlmén & A. Perski Comparison of fosinopril and hydrochloro- thiazide in patients with mild to moderate LETTERS TO THE EDITOR hypertension T. Forslund, P. Franzén & R. Backman INDEX N-acetylcysteine and serum concentrations of lipoprotein(a) A. A. Kroon, P. N. M. Demacker & P. H. Stalenhoef