Volume 171 JANUARY-JUNE 1995 The Journal of Infectious Diseases An Official Publication of the Infectious Diseases Society of America EDITORS & STAFF Petter Brandtzaeg, Oslo, Norway Marvin Turck, Editor José Campos, Madrid, Spain Lawrence Corey, Associate Editor John E. Edwards, Jr., Torrance, California Denise A. Galloway, Associate Editor Kathryn M. Edwards, Nashville, Tennessee Adam P. Geballe, Associate Editor Anne A. Gershon, New York, New York Steve Moseley, Associate Editor Richard L. Guerrant, Charlottesville, Virginia Henry Rosen, Associate Editor Scott B. Halstead, New York, New York Walter E. Stamm, Associate Editor Tapani Hovi, Helsinki, Finland Wesley C. Van Voorhis, Associate Editor Robert B. Jones, Indianapolis, Indiana Christopher B. Wilson, Associate Editor Stefan H. E. Kaufmann, Ulm, Germany Jacqueline K. Benedetti, Statistical Editor P. Helena Makela, Helsinki, Finland Donna Z. Mirkes, Assistant Editor Gerald L. Mandell, Charlottesville, Virginia Marie Leonard, Managing Editor David Mirelman, Rehovot, Israel Kathleen A. Murray, Manuscript Editor Robert S. Munford, Dallas, Texas Claudia C. Chesley, Manuscript Editor William M. Nauseef, lowa City, lowa Susan A. Balestreri, Manuscript Editor Harold C. Neu, New York, New York Cynthia A. Metzger, Manuscript Coordinator Matthew Pollack, Bethesda, Maryland Jean M. Ferguson, Manuscript Coordinator Thomas C. Quinn, Baltimore, Maryland Jack S. Remington, Palo Alto, California Allan B. Rickinson, Birmingham, United Kingdom EDITORIAL ADVISORY BOARD Allan Ronald, Winnipeg, Canada Frederick S. Southwick, Gainesville, Florida Jacques F. Acar, Paris, France Nicholas J. White, Bangkok, Thailand Miriam J. Alter, Atlanta, Georgia Richard J. Whitley, Birmingham, Alabama Ann M. Arvin, Stanford, California Martin J. Blaser, Nashville, Tennessee All rights reserved THE UNIVERSITY OF CHICAGO PRESS, CHICAGO THE UNIVERSITY OF CHICAGO PRESS LTD., LONDON SWI © 1995 BY THE UNIVERSITY OF CHICAGO PUBLISHED MONTHLY PRINTED IN USA The Journal of Infectious Diseases Volume 171 © Number 1 January 1995 Agency Reports 61 In Vitro Inhibition of Human Immunodeficiency Virus Type | by a Combination of Delavirdine (U-90152) with 1 Protective and Disease-Enhancing Immune Responses to Protease Inhibitor U-75875 or Interferon-a Respiratory Syncytial Virus Paul J. Pagano and Kong-Teck Chong Larry J. Anderson and Carole A. Heilman 68 Human Immunodeficiency Virus and Mycobacterium 8 Summary of the 29th United States-Japan Joint avium Complex Coinfection of Monocytoid Cells Conference on Cholera and Related Diarrheal Diseases Results in Reciprocal Enhancement of Multiplication Dennis R. Lang and Richard L. Guerrant Mahmood Ghassemi, Burton R. Andersen, Venkata M. Reddy, Pattisapu R. J. Gangadharam, Major Articles Gregory T. Spear, and Richard M. Novak 13 Age-Related Differences in Cell-Mediated Immunity to 74 Selective Depletion of V8-Bearing T Cells in Patients Varicella-Zoster Virus among Children and Adults with Severe Invasive Group A Streptococcal Infections Immunized with Live Attenuated Varicella Vaccine and Streptococcal Toxic Shock Syndrome Sonia Nader, Randy Bergen, Margaret Sharp, Rika Watanabe-Ohnishi, Donald E. Low, and Ann M. Arvin Allison McGeer, Dennis L. Stevens, Patrick M. Schlievert, Duane Newton, 18 Formulation of an Immunogenic Human Benjamin Schwartz, Barry Kreiswirth, Cytomegalovirus Vaccine: Responses in Mice Ontario Streptococcal Study Project, and Malak Kotb William Britt, Jaydie Fay, Jon Seals, and Charlotte Kensil 85 A Role for Fibrinogen in the Streptokinase-Dependent Acquisition of Plasmin(ogen) by Group A Streptococci 26 Immunity Induced by Primary Human Cytomegalovirus Hong Wang, Richard Lottenberg, Infection Protects against Secondary Infection among and Michael D. P. Boyle Women of Childbearing Age Stuart P. Adler, Stuart E. Starr, Stanley A. Plotkin, 93 The Impact of Conjugate Vaccine on Carriage of Sue H. Hempfling, Judy Buis, Mary Lou Manning, Haemophilus influenzae Type b and Al M. Best Marina L. Barbour, Richard T. Mayon- White, Clare Coles, Derrick W. M. Crook, 33 Cervical but Not Urinary Excretion of Cytomegalovirus and E. Richard Moxon Is Related to Sexual Activity and Contraceptive Practices in Sexually Active Women 99 Transplacental Antibody Transfer following Maternal Ann C. Collier, H. Hunter Handsfield, Rhoda Ashley, Immunization with Polysaccharide and Conjugate Pacita L. Roberts, Tim DeRouen, Joel D. Meyers, Haemophilus influenzae Type b Vaccines and Lawrence Corey Janet A. Englund, W. Paul Glezen, Connie Turner, Jonathan Harvey, Claudette Thompson, 39 Cytomegalovirus Infection Is Associated with Absence of and George R. Siber Alveolar Epithelial Cell HLA Class II Antigen Expression Christine L. Ng-Bautista and Daniel D. Sedmak 106 Comparison of Different 6-Lactam—Glycopeptide- Gentamicin Combinations for an Experimental 45 The Molecular Epidemiology of Human Endocarditis Caused by a Highly 6-Lactam-Resistant Immunodeficiency Virus Type | in Edinburgh and Highly Glycopeptide-Resistant Isolate of Edward C. Holmes, Lin Qi Zhang, Pamela Robertson, Enterococcus faecium Alexander Cleland, Elizabeth Harvey, Peter Simmonds, Francois Caron, Martine Pestel, and Andrew J. Leigh Brown Marie-Dominique Kitzis, Jean-Francois Lemeland, 54 Long-Term Efficacy of Active Postexposure Guy Humbert, and Laurent Gutmann Immunization of Infants for Prevention of Hepatitis B 113 The Effect of Variations in the Expression of Pili on the Virus Infection interaction of Neisseria meningitidis with Human Zhi-yi Xu, Shu-Cheng Duan, Harold S. Margolis, Nasopharyngeal Epithelium Robert H. Purcell, Pei- Ying Ou-yang, C. F. J. Rayner, A. Dewar, E. R. Moxon, M. Virji, Patrick J. Coleman, Yi-Liang Zhuang, Hua-Fang Xu, and R. Wilson Shui-Gen Qian, Qi-Rong Zhu, Cai-Yu Wan, Chung-Bo Liu, Zhi-Li Gun, and the United States-People’s Republic of China Study Group on Hepatitis B 122 Molecular Subtyping of Toxigenic Vibrio cholerae 0139 182 Virus-Specific Antibody Responses to Human Causing Epidemic Cholera in India and Bangladesh, Cytomegalovirus (HCMV) in Human Immunodeficiency 1992-1993 Virus Type I-Infected Persons with HCMV Retinitis Tanja Popovic, Patricia I. Fields, Orjan Olsvik, Suresh B. Boppana, Michael A. Polis, Joy G. Wells, Gracia M. Evins, Daniel N. Cameron, Andrew A. Kramer, William J. Britt, J. J. Farmer II, CherylA . Bopp, and Scott Koenig Kaye Wachsmuth, R. Bradley Sack, M. John Albert, Enhancement of NK Cell—Mediated Antibody- G. Balakrish Nair, Toshio Shimada, Dependent Lysis of Recombinant gp!20-Coated CD4 and John C. Feeley Cells by Complement 128 Correlation between Susceptibility of Infants to Susan J. Parker, Tania A. Sadlon, and David L. Gordon Infections and Interaction with Neutrophils of Infection of Oral Mucosal Cells by Human Escherichia coli Strains Causing Neonatal and Infantile Immunodeficiency Virus Type | in Seropositive Persons Septicemia M. Nasar Qureshi, Charles E. Barr, Lena Ohman, Kjell Tullus, Mohammad Katouli, Thikkavarapu Seshamma, Jason Reidy, Lars G. Burman, and Olle Stendahl Roger J. Pomerantz, and Omar Bagasra Effects of Endotoxin in the Lungs of Neonatal Rats: Detection of Hepatitis B Virus Precore TAG Mutant by Age-Dependent Impairment of the Inflammatory an Amplification-Created Restriction Site Method Response Magnus Lindh, Yasushi Furuta, Karin Kidd Ljunggren, Thomas R. Martin, John T. Ruzinski, Gunnar Norkrans, and Peter Horal Christopher B. Wilson, and Shawn J. Skerrett 5 Increased Circulating Cytokines, Cytokine Antagonists, Parenteral Influenza Vaccination Induces a Rapid and E-Selectin after Intravenous Administration of Systemic and Local Immune Response Endotoxin in Humans Karl A. Brokstad, Rebecca J. Cox, Jan Olofsson, Douglas B. Kuhns, W. Gregory Alvord, Roland Jonsson, and Lars R. Haaheim and John I. Gallin A Universal Approach to Bacterial Molecular Protective Effects of aR ecombinant Amino-Terminal Epidemiology by Polymerase Chain Reaction Ribotyping Fragment of Human Bactericidal/Permeability- Jay R. Kostman, Mitchell B. Alden, Michael Mair, Increasing Protein in an Animal Model of Gram- Thomas D. Edlind, John J. LiPuma, Negative Sepsis and Terrence L. Stull T. J. Evans, A. Carpenter, D. Moyes, R. Martin, Brazilian Purpuric Fever Caused by Haemophilus and J. Cohen influenzae Biogroup Aegyptius Strains Lacking the 3031 Effect of Interleukin-1 Receptor Antagonist and Soluble Plasmid Tumor Necrosis Factor Receptor in Animal Models of Maria Lucia Cecconi Tondella, Frederick D. Quinn, Infection and Bradley A. Perkins Maira M. Paris, lan R. Friedland, Stuart Ehrett, Flagellar Serotypes of Salmonella typhi in Indonesia: Sheila M. Hickey, Kurt D. Olsen, Relationships among Motility. Invasiveness, and Clinical Eric Hansen, Eugene J.-M. A. Thonar, Illness and George H. McCracken, Jr. Daniel A. Grossman, Nancy D. Witham, Temporal Trends and Transmission Patterns during the Donald H. Burr, Murad Lesmana, Fran A. Rubin, Emergence of Multidrug-Resistant Tuberculosis in New Gary K. Schoolnik, and Julie Parsonnet York City: A Molecular Epidemiologic Assessment Nasal Carriage of Staphylococcus aureus as a Major Risk Robert W. Shafer, Peter M. Small, Christina Larkin, Factor for Wound Infections after Cardiac Surgery Samir P. Singh, Patricia Kelly, Marcellino F. Sierra, J. A.J. W. Kluyimans, J. W. Mouton, Gary Schoolnik, and Keith D. Chirgwin E. P. F. Ijzerman, C. M. J. E. Vandenbroucke-Grauls, A. W. P. M. Maat, J. H. T. Wagenvoort, Concise Communications and H. A. Verbrugh 177 Quantitation of Human Cytomegalovirus DNA from Potentiation of Staphylococcus epidermidis Catheter- Peripheral Blood Cells of Human Immunodeficiency Related Bacteremia by Lipid Infusions Virus-Infected Patients Could Predict Cytomegalovirus Hiroyuki Shiro, Eugene Muller, Shugo Takeda, Retinitis Tor D. Tosteson, Donald A. Goldmann, Lucy Rasmussen, Shannon Morris, Donato Zipeto, and Gerald B. Pier Jeffrey Fessel, Richard Wolitz, Anna Dowling, and Thomas C. Merigan 225 Increase in Interleukin-6 Serum Level Preceding Fever in 245 Disseminated Microsporidiosis Due to Septata Granulocytopenia and Correlation with Death from intestinalis in Patients with AIDS: Clinical Features and Sepsis Response to Albendazole Therapy H. Tilman Steinmetz, Annette Herbertz, Jean-Michel Molina, Eric Oksenhendler, Monika Bertram, and Volker Diehl Bernadette Beauvais, Claudine Sarfati, Arnaud Jaccard, Francis Derouin, and Jacques Modai’ 229 High Levels of Interleukin-10 during the Initial Phase of Fulminant Meningococcal Septic Shock 249 6 T Cells and Acute Primary Toxoplasma gondii Bert Derkx, Arnaud Marchant, Michel Goldman, Infection in Mice Rob Bijlmer, and Sander van Deventer Peter C. Sayles, Alexander L. Rakhmilevich, and Lawrence L. Johnson 232 Increased Plasma Levels of Human Interleukin for DA|.a Cells/Leukemia Inhibitory Factor in Sepsis Correlate with Shock and Poor Prognosis Correspondence Daniel Villers, Trinh Dao, Jean-Michel Nguyen, 253 Mefloquine Prophylaxis in Pregnancy Evelyne Bironneau, Anne Godard, Martine Moreau, A. Clinton White, Jr.. and James H. Runnels Donat De Groote, Francoise Nicolas, Jean-Paul Soulillou, and Ignacio Anegon 253 Epitopes on Surface Antigens Other than OspA Can Elicit a Bactericidal Effect against Lyme Disease Borrelias 237 Catalase Expression, katG, and MIC of Isoniazid for Russell J. Shoberg and D. Denée Thomas Mycobacterium tuberculosis Isolates from Sao Paulo, Brazil 254 Increased Human Papillomavirus Infection with the Lucilaine Ferrazoli, Moises Palaci, Increasing Number of Pregnancies in Indian Women Maria Alice da Silva Telles, Suely Yoko Ueki, V. Gopalkrishna, N. S. Murthy, J. K. Sharma, Afranio Kritski, Lilian Regina Macelloni Marques, Meera Roy, D. K. Das, Usha K. Luthra, Orlando C. Ferreira, and Lee W. Riley and B. C. Das 240 Rapid Identification of a Point Mutation of the 256 Serum IgA Antibody Response to Cryptosporidium Mycobacterium tuberculosis Catalase-Peroxidase (katG) parvum Is Mainly Represented by IgA1 Gene Associated with Isoniazid Resistance L. Favennec, E. Comby, J. J. Ballet, and P. Brasseur Frank R. Cockerill IIT, James R. Uhi, 257 Notices Zelalem Temesgen, Ying Zhang, Leslie Stockman, Glenn D. Roberts, Diana L. Williams, and Bruce C. Kline 258 IDSA Membership Information Instructions for Authors Volume 171 © Number 2 February 1995 Major Articles 281 Application of Six Hepatitis C Virus Genotyping Systems to Sera from Chronic Hepatitis C Patients in the 263 Bidirectional Transmission of Infectious United States Cytomegalovirus between Monocytes and Vascular Johnson Y. N. Lau, Masashi Mizokami, Endothelial Cells: An In Vitro Model Janice A. Kolberg, Gary L. Davis, Linda E. Prescott, W. James Waldman, Deborah A. Knight. Tomoyoshi Ohno, Robert P. Perrillo, Karen L. Lindsay, Emina H. Huang, and Daniel D. Sedmak Robert G. Gish, Ke-Ping Qian, Michinori Kohara, 273 Detection of Human Herpesvirus 6 in Plasma of Peter Simmonds, and Mickey S. Urdea Children with Primary Infection and Immunosuppressed 290 Lombok Hepatitis B Model Immunization Project: Patients by Polymerase Chain Reaction Toward Universal Infant Hepatitis B Immunization in Paola Secchiero, Donald R. Carrigan, Yoshizo Asano, Indonesia Laura Benedetti, Richard W. Crowley, Tilman A. Ruff. Dorota M. Gertig, Bradley F. Otto, Anthony L. Komaroff. Robert C. Gallo, Tan D. Gust, Agustinus Sutanto, and Paolo Lusso Titi Indijati Soewarso, Nyoman Kandun, Tan C. Marschner, and James E. Maynard 297 Phase I Study of Atevirdine, a Nonnucleoside Reverse Early Murine Lyme Carditis Has a Macrophage Transcriptase Inhibitor, in Combination with Predominance and Is Independent of Major Zidovudine for Human Immunodeficiency Virus Type | Histocompatibility Complex Class II-CD4* T Cell Infection Interactions Richard C. Reichman, Gene D. Morse, Eric M. Ruderman, Janet S. Kerr, Sam R. Telford Il, Lisa M. Demeter, Lionel Resnick, Yiannis Bassiakos, Andrew Spielman, Laurie H. Glimcher, Margaret Fischl, Michael Para, William Powderly, and Ellen M. Gravallese John Leedom, Carol Greisberger, Tom Nevin, Antimicrobial-Resistant Epidemic Shigella dysenteriae Ken Wood, Patricia M. Meehan, Heidi Geheb, Type | in Zambia: Modes of Transmission Steve Cox, Donald Batts, Joseph Timpone, Jr., Jessica Tuttle, Allen A. Ries, Rov M. Chimba, and the ACTG 199 Study Team C. U. Perera, Nancy H. Bean, Human Immunodeficiency Virus Type | Quantitative and Patricia M. Griffin Cell Microculture as a Measure of Antiviral Efficacy in Cytokine Secretion in Acute Shigellosis Is Correlated to a Multicenter Clinical Trial Disease Activity and Directed More to Stool than to Susan A. Fiscus, Victor DeGruttola, Phalguni Gupta, Plasma David A. Katzenstein, William A. Meyer III, Rubhana Ragib, Bengt Wretlind, Jan Andersson, Marsha L. LoFaro, Michael Katzman, and AlfA . Lindberg Margaret V. Ragni, Patricia S. Reichelderfer, and Robert W. Coombs Modulation of Nonspecific Antimicrobial Resistance of Mice to Klebsiella pneumoniae Septicemia by Liposome- 312 Association between Anti-CD4 Antibodies and a Encapsulated Muramyl Tripeptide Decline in CD4* Lymphocytes in Human Phosphatidylethanolamine and Interferon-y Alone or Immunodeficiency Virus Type | Seroconverters Combined Susan Keay, Wayne Wecksler, Steven S. Wasserman, Timo L. M. ten Hagen, Wim van Vianen, Joseph Margolick, and Homayoon Farzadegan and Irma A. J. M. Bakker- Woudenberg Macrophages from Human Immunodeficiency Pharmacologic Inhibitors of Tumor Necrosis Factor Virus—Positive Persons Are Defective in Host Defense Production Exert Differential Effects in Lethal against Histoplasma capsulatum Endotoxemia and in Infection with Live Microorganisms Sudha Chaturvedi, Peter Frame, and Simon L. Newman in Mice Depressed CD4* T Lymphocyte Proliferative Response Mihai G. Netea, Willem L. Blok, Bart-Jan Kullberg, and Enhanced Antibody Response to Viral Antigen in Marc Bemelmans, Maria T. E. Vogels, Chronic Lentivirus-Induced Arthritis Wim A. Buurman, and Jos W. M. van der Meer Linda L. Perry, Melinda J. Wilkerson, Gordon A. Hullinger, and William P. Cheevers Exacerbation of Acute and Chronic Murine Tuberculosis by Administration of aT umor Necrosis Factor Interactions of Surfactant Protein A with Influenza A Receptor—-Expressing Adenovirus Viruses: Binding and Neutralization L. B. Adams, C. M. Mason, J. K. Kolls, D. Scollard. C. A. Benne, C. A. Kraaijeveld, J. A. G. van Strijp, J. L. Krahenbuhl, and S. Nelson E. Brouwer, M. Harmsen, J. Verhoef. Fluconazole and Amphotericin B Antifungal Therapies L. M. G. van Golde, and J. F. van Iwaarden Do Not Negate the Protective Effect of Endogenous Hematogenous Bacterial Meningitis in an Intercellular Tumor Necrosis Factor in a Murine Model of Fatal Adhesion Molecule-1—Deficient Infant Mouse Model Disseminated Candidiasis Tina Q. Tan, C. Wayne Smith, Edith P. Hawkins, Arnold Louie, Aldona L. Baltch, Raymond P. Smith, Edward O. Mason, Jr., and Sheldon L. Kaplan Mary A. Franke, William J. Ritz, Jaswant K. Singh, and Morris A. Gordon Phagocytosis of Streptococcus pneumoniae Measured In Vitro and In Vivo in a Rat Model of Carbon Preferential Recognition by Human IgE and IgG4 of a Tetrachloride—Induced Liver Cirrhosis Species-Specific Schistosoma haematobium Serine Martha J. Gentry, Mary U. Snitily, Protease Inhibitor and Laurel C. Preheim Zujin Li, Christopher L. King, John O. Ogundipe, Lucila S. Licate, and Ronald E. Blanton Biliary Complications in the Treatment of Unsubstantiated Lyme Disease Paul J. Ettestad, Grant L. Campbell, Sharon F. Welbel, Editorial Carol A. Genese, Kenneth C. Spitalny, 423 Lyme Disease: Primum Non Nocere Carl M. Marchetti, and David T. Dennis Leonard H. Sigal Concise Communications Induction of Urinary Tract Infection by Intraurethral Inoculation with Escherichia coli: Refining the Murine 425 Rare Association of Human Papillomavirus DNA with Model Esophageal Cancer in Japan Walter J. Hopkins, Jennifer A. Hall, Brett P. Conway, Naotake Akutsu, Hiroshi Shirasawa, Koichi Nakano, and David T. Uehling Hideki Tanzawa, Takehide Asano, Susumu Kobayashi, Kaichi Isono, and Bunsiti Simizu Heterogeneity of Enteroaggregative Escherichia coli Virulence Demonstrated in Volunteers 429 Genital Human Papillomavirus Infection among Male James P. Nataro, Deng Yikang, Susan Cookson, and Female Sex Partners: Prevalence and Type-Specific Alejandro Cravioto, Stephen J. Savarino, Concordance Linda D. Guers, Myron M. Levine, Leslie A. Baken, Laura A. Koutsky, Jane Kuypers, and Carol O. Tacket Michael R. Kosorok, Shu-Kuang Lee, Nancy B. Kiviat, and King K. Holmes Circulating Interleukin-6 Receptor in Patients with Sepsis Syndrome 432 Human Cytomegalovirus DNA Is Present in CD45* Johan T. M. Frieling, Marcel van Deuren, Cells in Semen from Human Immunodeficiency John Wijdenes, Jos W. M. van der Meer, Virus-Infected Patients Claude Clement, Cees J. van der Linden, Lucy Rasmussen, Shannon Morris, Kamal Hamed, and Robert W. Sauerwein and Thomas C. Merigan Interleukin-10 and the Monocyte/Macrophage-Induced 437 Immunization of Chimpanzees with Recombinant Inflammatory Response in Septic Shock gp160, but Not Infection with Human J. Gomez-Jiménez, M. C. Martin, R. Sauri, Immunodeficiency Virus Type |, Induces R. M. Segura, F. Esteban, J. C. Ruiz, X. Nuvials, Envelope-Specific Thl Memory Cells J. L. Boveda, R. Peracaula, and A. Salgado Josef W. Mannhalter, Michael B. Fischer, Hermann M. Wolf. Zaruhi Kiipcii, Noel Barrett, Nondifferentiation between Lyme Disease Spirochetes Friedrich Dorner, Gerald Eder, and Martha M. Eibl from Vector Ticks and Human Cerebrospinal Fluid Helmut Eiffert, Andreas Ohlenbusch, 440 Systemic Immunoprophylaxis of Nasal Respiratory Hans-Jtirgen Christen, Reiner Thomssen, Syncytial Virus Infection in Cotton Rats Andrew Spielman, and Franz-Rainer Matuschka Iman R. Sami, Franco M. Piazza, Susan A. Johnson, Miriam E. R. Darnell, Martin G. Ottolini, Diagnosis of Bacteremic Pneumococcal Pneumonia by Val G. Hemming, and Gregory A. Prince Amplification of Pneumolysin Gene Fragment in Serum Paula Salo, Ake Ortqvist, and Maija Leinonen 443 Quantitative Branched DNA Assay and Genotyping for Hepatitis C Virus RNA in Chinese Patients with Acute In Vitro Activity of Subinhibitory Concentrations of and Chronic Hepatitis C Quinolones on Urea-Splitting Bacteria: Effect on Urease Cho-Yu Chan, Shou-Dong Lee, Shinn-Jang Hwang, Activity and on Cell Surface Hydrophobicity Rei-Hwa Lu, Cheng-Leurn Lu, and Kwang-Juei Lo M. A. Ramadan, A. F. Tawfik, T. A. El-Kersh, and A. M. Shibl 447 Age-Specific Prevalence of Antibodies to Hepatitis A and E Viruses in Pune, India, 1982 and 1992 Divergent Effects of Zinc on Different Bacterial Vidya A. Arankalle, Sergei A. Tsarey, Pathogenic Agents Mandeep S. Chadha, David W. Alling. Christoph Driessen, Kaimo Hirv, Holger Kirchner, Suzanne U. Emerson, Kalyan Banerjee, and Lothar Rink and Robert H. Purcell Malaria in East African Refugees Resettling to the 451 Sexually Transmitted Diseases and Human United States: Development of Strategies to Reduce the Immunodeficiency Virus Control in Malawi: Risk of Imported Malaria A Field Study of Genital Ulcer Disease Laurence Slutsker, Margaret Tipple, Vincent Keane, Frieda M.-T. Behets, George Liomba, Godfrey Lule, Charles McCance, and Carlos C. Campbell Gina Dallabetta, Irving F. Hoffman, Holli A. Hamilton, Trypanosoma cruzi Induces Endothelin Release from Stoffel Moeng, and Myron S. Cohen Endothelial Cells 455 Pulsed-Field Gel Electrophoresis for Genomic Analysis Murray Wittner, George J. Christ, Huan Huang, of Neisseria gonorrhoeae Louis M. Weiss, Victor B. Hatcher, Stephen A. Morris, Minsheng Xia, William L. Whittington, George A. Orr, Joan W. Berman, Guillermo A. Zeballos, King K. Holmes, Francis A. Plummer, Stephen A. Douglas, and Herbert B. Tanowitz and Marilyn C. Roberts Soluble Receptors for Tumor Necrosis Factor as Markers 459 Virulence of Coccoid and Bacillary Forms of of Disease Activity in Visceral Leishmaniasis Helicobacter pylori in Gnotobiotic Piglets E. E. Zijlstra, T. van der Poll, and M. Mevissen K. A. Eaton, C. E. Catrenich, K. M. Makin, and S. Krakowka Correspondence International Inter- and Intrahospital Patient Spread of a Multiple Antibiotic—Resistant Strain of Klebsiella 502 Infection with Human Immunodeficiency Virus Type | pneumoniae among Leprosy Patients in Zaire Barry Cookson, Alan P. Johnson, Berge Azadian, Sebastian B. Lucas, Paul E. M. Fine, John Paul, Graham Hutchinson, Mary Kaufmann, Jonathan A. C. Sterne, Jorg M. Pénnighaus, Neil Woodford, Miraj Malde, Barry Walsh, Amanda C. Turner, Kevin M. De Cock, Aziz Yousif. and Joseph Selkon and Mark Zuckerman Emergence of Serotype V Group B Streptococcal 503 Reply Infection among Infants and Adults Oscar Kashala, Richard Marlink, Mbayo Ilunga, Lee H. Harrison, Diane M. Dwyer, Mulamba Diese, Bobby Gormus, Keyu Xu, and Judith A. Johnson Prudence Mukeba, Kabasele Kasongo, and Max Essex Detection of Serum Antibodies to the Lipopolysaccharide of Escherichia coli 0103 in Patients 504 The Predictive Value of a Serologic Test for the with Hemolytic-Uremic Syndrome Detection of Babesia microti Antibody Ida Luzzi, Alberto E. Tozzi, Gianfranco Rizzoni, A. Van Gompel, J. Van den Ende, and E. Van den Enden Antonio Niccolini, Ildo Benedetti, Fabio Minelli, 505 Reply and Alfredo Caprioli Peter J. Krause, Sam R. Telford HI, Raymond Ryan, Human Microsporidiosis in African AIDS Patients with Patricia A. Conrad, Marianna Wilson, Chronic Diarrhea John W. Thomford, and Andrew Spielman F. Drobniewski, P. Kelly, A. Carew, B. Ngwenya, 506 No Evidence of Long-Term Immunosuppression after N. Luo, C. Pankhurst, and M. Farthing High-Titer Edmonstron-Zagreb Measles Vaccination Human Astrocytes Inhibit Intracellular Multiplication of in Senegal Toxoplasma gondii by a Nitric Oxide—Mediated Badara Samb, Hilton Whittle, Peter Aaby, Mechanism Awa Marie Coll Seck, John Bennett, Lauri Markowitz, Phillip K. Peterson, Genya Gekker, Shuxian Hu, Pa Tamba Ngom, Hervé Zeller, and Chun C. Chao Kim Fleischer Michaelsen, and Francois Simondon 508 Disseminated Acyclovir-Resistant Herpes Simplex Virus 519 Notices Type 2 Treated Successfully with Foscarnet Timothy J. Jones and Richard Paul 519 Erratum 509 Human Immunodeficiency Virus Type |-Infected Patients with No Disease Progression Display Instructions for Authors High-Avidity Antibody Production to Autologous V3 Sequences Christina Brostrém, Anders Sénnerborg, and Matti Sdllberg Volume 171 © Number 3 March 1995 Editorial 531 T Cell Function In Vitro Is an Independent Progression Marker for AIDS in Human Immunodeficiency 521 Reducing T Cell Activation as a Therapy for Human Virus—-Infected Asymptomatic Subjects Immunodeficiency Virus Infection Marijke T. L. Roos, Frank Miedema, Maarten Koot, Lawrence Corey Matthijs Tersmette, Wim P. Schaasberg, Roel A. Coutinho, and Peter T. A. Schellekens Major Articles 523 Sustained Increases in CD4 Cell Counts in Asymptomatic Human Immunodeficiency Virus Type 1-Seropositive Patients Treated with Prednisolone for 1 Year Jean-Marie Andrieu, Wei Lu, and Rafael Levy 537 High-Dose Nevirapine: Safety, Pharmacokinetics, and 607 Effects of Staphylococcus aureus Leukocidins on Antiviral Effect in Patients with Human Inflammatory Mediator Release from Human Immunodeficiency Virus Infection Granulocytes Diane Havlir, Sarah H. Cheeseman, B. Kénig, G. Prévost, Y. Piémont, and W. Kénig Margaret McLaughlin, Robert Murphy, Alejo Erice, Stephen A. Spector, Thomas C. Greenough, 614 Eradication of Endemic Methicillin-Resistant John L. Sullivan, David Hall, Maureen Myers, Staphylococcus aureus Infections from a Neonatal Michael Lamson, and Douglas D. Richman Intensive Care Unit Robert W. Haley, Nancy B. Cushion, Fred C. Tenover, 546 Reduction of the In Vitro Activity of A77003, an Tammy L. Bannerman, Donna Dryer, Jillian Ross, Inhibitor of Human Immunodeficiency Virus Protease, Pablo J. Sanchez, and Jane D. Siegel by Human Serum a, Acid Glycoprotein J. A. Bilello, P. A. Bilello, Mark Prichard, Terry Robins, 625 Intestinal Carriage of P Fimbriated Escherichia coli and and G. L. Drusano the Susceptibility to Urinary Tract Infection in Young Children 552 Chronic Bacterial Enteropathy in Patients with AIDS Kaety Plos, Hugh Connell, Ulf Jodal, Britt-Inger Donald P. Kotler, Tony T. Giang, Michael Thiim, Marklund, Staffan Marild, Bjorn Wettergren, James P. Nataro, Emilia M. Sordillo, and Catharina Svanborg and Jan M. Orenstein 632 A Trial of aG roup A plus Group C Meningococcal 559 Incidence of Human T Lymphotropic Virus Type I Polysaccharide—Protein Conjugate Vaccine in African Seroconversion after Age 40 among Japanese Residents Infants in an Area Where the Virus Is Endemic Patrick A. Twumasi, Jr., Samuel Kumah, Toshiro Takezaki, Kazuo Tajima, Haruko Komoda, Amanda Leach, Timothy J. D. O‘Dempsey, and Johko Imai Serign J. Ceesay, James Todd, Claire V. Broome, 566 Viral Shedding and Fecal IgA Response after Norwalk George M. Carlone, Lorna B. Pais, Patricia K. Holder, Brian D. Plikaytis, Virus Infection and Brian M. Greenwood Pablo C. Okhuysen, Xi Jiang, Liming Ye, Philip C. Johnson, and Mary K. Estes 639 Increased Circulating Soluble CD14 Is Associated with High Mortality in Gram-Negative Septic Shock 570 Adenovirus-Mediated Blockade of Tumor Necrosis Regine Landmann, Werner Zimmerli, Factor in Mice Protects against Endotoxic Shock yet Sebastiano Sansano, Susanne Link, Alfred Hahn, Impairs Pulmonary Host Defense Michel Pierre Glauser, and Thierry Calandra Jay K. Kolls, Dinghua Lei, Steve Nelson, Warren R. Summer, Stanley Greenberg, 645 A Recombinant Cysteine-Rich Section of the Entamoeba and Bruce Beutler histolytica Galactose-Inhibitable Lectin Is Efficacious as a Subunit Vaccine in the Gerbil Model of Amebic Liver 576 Analysis of the UL97 Phosphotransferase Coding Abscess Sequence in Clinical Cytomegalovirus Isolates and Identification of Mutations Conferring Ganciclovir Chu-Jing Ginny Soong. Kevin C. Kain, Mohamed Abd-Alla, Terry F. H. G. Jackson, Resistance and Jonathan I. Ravdin Sunwen Chou, Alejo Erice, M. Colin Jordan, Gregory M. Vercellotti, Kendall R. Michels, 652 Immunity to Onchocerciasis: Putative Immune Persons Christine L. Talarico, Sylvia C. Stanat, Produce a Th1-like Response to Onchocerca volvulus and Karen K. Biron Lynne H. Elson, Manuel Calvopiiia H.. 584 Nasal Cytokine Production in Viral Acute Upper Wilson Paredes Y., Edmundo Araujo N., Respiratory Infection of Childhood Janette E. Bradley, Ronald H. Guderian, Terry L. Noah, Frederick W. Henderson, and Thomas B. 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