Table Of Content

Author Index Beeley, J. A. Marshall, T., Williams, J. and Williams, K. M. Clinical applications of electrophoresis of Electrophoresis of serum isoenzymes and human salivary proteins (Review) proteins following acute myocardial 569(1991)261 infarction (Review) 569(1991)323 Bianchi-Bosisio, A., D’Agrosa, F., Gaboardi, F., Prusik, Z., see KaSiéka, V. 569(1991)123 Gianazza, E. and Righetti, P. G. Righetti, P. G. and Deyl, Z. Sodium dodecyl sulphate electrophoresis of Preface 569(1991)1 urinary proteins (Review) 569(1991)243 Righetti, P. G., Gianazza, E., Bianchi-Bosisio, A., Bianchi-Bosisio, A., see Righetti, P. G. Sinha, P. and K6ttgen, E. 569(1991)197 Isoelectric focusing in immobilized pH Boéek, P., see Kleparnik, K. 569(1991)3 gradients: applications in clinical chemistry Cupo, J. F. and forensic analysis (Review) Electrophoretic analysis of nuclear matrix 569(1991)197 proteins and the potential clinical Righetti, P. G., see Bianchi-Bosisio, A. applications (Review) 569(1991)389 569(1991)243 D’Agrosa, F., see Bianchi-Bosisio, A. Righetti, P. G., see Gianazza, E. 569(1991)43 569(1991)243 Sinha, P., see. Righetti, P.G. 569(1991)197 Deyl, Z. and Struzinsky, R. Struzinsky, R., see Deyl, Z. 569(1991)63 Capillary zone electrophoresis: its Suzuki, Y. applicability and potential in biochemical Electrophoresis of mutant proteins in analysis (Review) 569(1991)63 inherited diseases (Review) 569(1991)407 Deyl, Z., see Righetti, P.G. 569(1991)1 Syrovy, I. and Hodny, Z. Fukunaga, T., see Kane, M. 569(1991)297 Staining and quantification of proteins Gaboardi, F., see Bianchi-Bosisio, A. separated by polyacrylamide gel 569(1991)243 electrophoresis (Review) 569(1991)175 Gianazza, E. and Righetti, P. G. Taketa, K. Biomedical relevance of two-dimensional Clinical applications of lectin affinity protein mapping (Review) 569(1991)43 electrophoresis (Review) 569(1991)229 Gianazza, E., see Bianchi-Bosisio, A. Tatsuno, Y., see Kane, M. 569(1991)297 569(1991)243 Tozawa, T. Gianazza, E., see Righetti, P.G. 569(1991)197 Electrophoretic analysis of enzyme-linked Hodny, Z., see Syrovy, I. 569(1991)175 immunoglobulins and their clinical Kane, M., Fukunaga, T., Yamamoto, Y.., significance (Review) 569(1991)347 Yamada, M. and Tatsuno, Y. Unteregger, G. Electrophoretic phenotyping of erythrocyte Utility of protein electrophoretic analysis in enzymes (Review) 569(1991)297 the characterization of malignant tissues Kasi¢ka, V. and Prusik, Z. (Review) 569(1991)367 Application of capillary isotachophoresis in Wiederkehr, F. peptide analysis (Review) 569(1991)123 Analysis of cerebrospinal fluid proteins by Kleparnik, K. and Boéek, P. electrophoresis (Review) 569(1991)281 Theoretical background for clinical and Williams, J., see Marshall, T. 569(1991)323 biomedical applications of electromigration Williams, K. M., see Marshall, T. 569(1991)323 techniques (Review) 569(1991)3 Wood, S. and Langlois, S. Kottgen, E., see Righetti, P.G. 569(1991)197 DNA typing in hereditary disease (Review) Langlois, S., see Wood, S. 569(1991)421 569(1991)421 Yamada, M., see Kane, M. 569(1991)297 Yamamoto, Y., see Kane, M. 569(1991)297 List of Compounds Separated Acetaminophen 113, 115 Apo high-density lipoprotein 137 Acetate 143 Apolipoprotein AI 48, 289, 291 N-2-Acetyllysine 143 Apolipoprotein AIV 291 a,-Acid glycoprotein 48, 200, 201, 238, 255, 291, Apolipoprotein B 289 409 Apolipoprotein C 48 a,-Acid glycoprotein, isoforms 238 Apolipoprotein CII 289 Acid phosphatase 201, 202, 299-303, 309, 313, 314, Apolipoprotein CIII 289 316, 348, 409 Apolipoprotein D 288, 291 Aconitase 409 Apolipoprotein E 48, 51, 288, 289, 294 ACTH 142, 143, 159, 160, 165 Apolipoprotein E-D 51 Actin 48, 181, 193, 291 Apolipoproteins 205-211 Adenosine deaminase 299, 409 Apolipoproteins, CSF-specific 291 Adenosine monophosphate 7 Apolipoproteins, isoforms 206 Adenosine phosphoribosyl transferase 52 Arginine 96-98, 186 Adenylate kinase 299, 409 (8-p-Arginine)—deaminovasopressin 166 Adiuretin 141, 167 8-L-Arginine-des-9-glycinamide 145 Adrenocorticotropic hormone, see ACTH Arginine—vasopressin 142, 160 Alanine 95-98 Asparagine 77 B-Alanine 7, 10 Aspartame 137, 141, 161 Alanine, enantiomers 90 Aspartate aminotransferase 337, 338, 348, 352, 355, Alanine aminotransferase 348, 358 357, 360 Albumin 47, 48, 93, 104, 194, 255, 262, 263, 268, Aspartic acid 77, 95-98 282, 291, 294 Aspoxicillin 116 Albumin/transferrin ratio 250 AST, see Aspartate aminotransferase Alkaline phosphatase 202, 203, 237, 348, 352, 353, Autoantibodies 381 355, 356, 359, 361 Auxilliary protein for DNA-polymerase 6 377 Allele-specific amplification 441 Bacitracin 139, 142, 159 Allele-specific ligation 441 Bee venoms 170 Allele-specific oligonucleotides 440, 441 Bence—Jones protein 253 ALP, see Alkaline phosphatase Benzyldimethylammonium 145 ALT alanine aminotransferase 348 Betamethasone 114 Altered restriction sites 440 Bicarbonate 156 Amines 76 Blood group substances 263 Amino acids 75-77, 79, 94-96, 98, 156, 160, 162, see Bombinin 141, 160 also individual amino acids Bradykinin 142 Amino acids, enantiomers 89-91 Bromide 143, 166 Ammediol 7 Cls inactivator 48 Ammonia 145, 166 Cls subcomponent 290 Amy | 270 C3 activator monomer 291 Amy 2 270 C3 preactivator 48 AMYL, see Amylase Caffeine 113, 115 Amylase 348-350, 353, 355, 356, 358, 359, 361, 409 Calcitonin 159 a-Amylase 262, 263, 268, 270 Calmodulin 188 Amylase, isozymes 275 Cancer cells 377 Amylase, P-type 270 Carbetocin 167 Angiotensin 99, 136, 137 Carbonic anhydrase 104, 191, 249, 395, 409 (1-Asn,5-Val)Angiotensin II-diacetate 142 Carboxylic acids 117 Antibiotics 114 S-Carboxymethylcysteine 116 a,-Antichymotrypsin 48, 238, 291 Carboxypeptidase 411 Antithrombin III 48 Carcinoembryonic antigen 46 a,-Antitrypsin 48, 200, 203-205, 291, 409 Catalase 191 a,-Antitrypsin, dimer 291 Catechols 81, 117 a,-Antitrypsin, isoforms 204 Cefpyramide 116 450 Cephalosporins 116 fB-Endorphin 141, 145, 159 Ceruloplasmin 48, 338, 409 Enolase 289 Chloride 7, 143, 166 Enzyme-linked immunoglobulins 347—362 Chloroacetate 143 Epidermal growth factor 263, 264 Cholecystokinin 142, 159, 160 Epinephrine, enantiomers 91 Cholesterol 205, 206 Erythrocyte enzymes 297-319 Cholesteryl esters 206 Esterase D 299, 309, 313, 409 Cholinesterase 409 Esterase D, isoenzymes 301-307, 313, 315-318 Chromatin 372, 373, 394 Ethanolamine 7 Chromatin proteins 378 Ethenzamide 113, 115 Chylomicrons 205 N-Ethylmorpholine 145, 166 Citrate 143, 166 Extracellular proteins, polymorphism 409 CK, see Creatine kinase Factor B (of human complement) 212 Cobalamin-binding proteins 275 Factor XIIIB (coagulation) 212—213 Collagen 106, 192, 412 Ferritin 191 Complement C2 409 a-Fetoprotein 233—237 Complement C3 211-212, 409 a-Fetoprotein, isoforms 234—237 Complement C3, isoforms 211 Fibrin 137, 159 Complement C4 409 Fibrinogen 48, 283, 291 Complement C6 409 Fibrin-stabilizing factor, see Factor XIIIB Corticosteroids 112, 114 Fibroblast proteins 416, 417 Cortisone 114 Fluocinolone acetonide 114 Creatine kinase 325-334, 348, 352, 355-358, 360— Fluocinonide 114 362 Fluoride 7 Creatine kinase, isoenzymes 325, 326, 328, 329, Formate 143, 166 331-333, 340 a-L-Fucosidase 409 Creatine kinase isoenzymes, nomenclature 327, 330 Galactose-l-uridyl transferase 409 Cyanogen bromide fragments 137, 138 a-Galactosidase 411 Cyclin 377, 378 B-Galactosidase 410-413 Cystatins 263, 271 Gelatin 179 Cysteine 96, 97 Genetic markers 424—429 Cystine 98 Glial fibrillary acidic protein 294 Cytidine deaminase 409 Glioblastoma-specific DNA-bound proteins 379 Cytochrome C 179 Ge Globulin 48 Cytosolic proteins 378 y-Globulins 275, 284, 285, 290 Deacetyldiltiazem 114 Glucose-6-phosphate dehydrogenase 299, 409 Dexamethasone 114 a-Glucosidase 409-41 1 Dicyclohexylamine 145, 166 Glutamate oxaloacetate transminase 299 Dideoxycytidine triphosphate 112 Glutamate pyruvate transaminase 209 Dietary tannins 263 Glutamic acid 77, 95—98 N,N-Diisopropylethylamine 145, 166 Glutamic-oxalacetic transaminase 409 Diltiazem 112, 114, 116 Glutamic-pyruvic transaminase 409 4-Dimethylaminopyridine 145, 166 Glutamine 77, 98 N-3,5-Dinitrobenzoylamino acid isopropyl esters a-Glutamyltransferase 237 89 a-Glutamyltransferase, isoforms 237 Dipeptides 154-156, 159, 160, 163, 164, 168 Glutathione 136, 138, 139, 167 Disarcosine 138 Glutathione peroxidase 409 DNA I11, 112, 184, 390, 393, 394, 397-400 Glutathione reductase 409 DNA, polymorphic 408 Glycated proteins 192 DNA-binding proteins 368, 375, 383 Glycine 76, 77, 95-98, 186, 188 DNA hydridization 432 a,AP-Glycoprotein 48 DNA markers 427, 428, 431-433 a,B-Glycoprotein 48, 291 DNA polymerase « 394 a,HS-Glycoprotein 48, 238, 291 DNase 395 f,-Glycoprotein 409 DNA typing 421-445 G4-Glycoprotein 291 Drugs 112-117 Glycoproteins 105, 184, 229-239, 275, see also indi- Elastase 348 vidual glycoprotein types Glyoxalase 409 Isoenzymes 349 Gonadoliberin 167 Isoenzymes, infarction 323—340 Gonadorelin 142, 161 Isoleucine 77, 96-98 Gramicidin S 179 Isopropylnoradrenaline 81 Group-specific component 213, 214 Kallikrein 263, 273, 275 Growth hormone 106, 137 Kallindin 142 Haemoglobin 220-223, 248, 313 a-Lactalbumin 249 Haemoglobin, f-chain 48 Lactate dehydrogenase 191, 334-337, 348, 351- Haemoglobin, variants 220 355, 357-359, 361, 395 Haemopexin 48, 137, 291 Lactate dehydrogenase, isoenzymes 334-337 Haptoglobin 409 Lactoferrin 263, 273 Haptoglobin, «,-chain 48 f-Lactoglobulin 102, 104 Haptoglobin, «,-chain 291 Lactoperoxidase 263 Haptoglobin, «,,-chain 291 Lamins 395 Haptoglobin, «,.-chain 291 LD, see Lactate dehydrogenase Haptoglobin, f-chain 48, 291 Lecithin:cholesterol acyltransferase 214, 215 Heteroduplex analysis 441, 442 Lecithin:cholesterol acyltransferase, isoforms 214 Hexacyanoferrate(II) 117 Leucine 77, 96-98 Hexacyanoferrate(III) 117 Leucine, enantiomers 90 Hexokinase 409 Leucine aminopeptidase 348 B-Hexososaminidase 410, 413-415 Leukocyte antigens 299 High-density lipoproteins 206 Lipase 348 High-molecular-mass DNA 429 Lipopolysaccharides 184 Histatins 262, 263, 271 Lipoprotein receptor 51 Histidine 96-98 Lipoproteins, isoforms 209 Histidine-rich polypeptides, see Histatins Lipoproteins, triglyceride-rich 209 Histones 184, 375 B-Lipotropic hormone 143, 165 HIV antibodies 275 Lithium 7 HIV antigens 275, 276 Low-density lipoproteins 206 Hydrazine 166 Lysine 76, 96, 97 Hydrocortisone 114 Lysine—vasopressin 142 Hydrocortisone acetate 114 Lysozyme 102, 179, 263 p-Hydroxybenzoates 113 a,-Macroglobulin 48, 283 1-Hydroxybenzotriazole 143 Maillard reaction products 117 4-(2-Hydroxyethyl)-1-piperazineethanesulphonic Malic enzyme 409 acid 7 Mellitin 170 Hydroxyl 7 Metallothioneins 191 Hydroxylysine 77 Methanesulphonate 143, 166 Hydroxyproline 98 Methionine 77, 95, 96, 98 5-Hydroxytryptamine 81 Methionine-lysine-bradykinin 142 Hypoxanthine phosphoribosyltransferase 52 Methotrexate 138 Imidazole 7 O-Methyloxytocin 142, 167 Immunoglobulin A 263, 283 a,-Microglobulin 54 Immunoglobulin A, heavy chain 291 B,-Microglobulin 247, 255 Immunoglobulin G 46, 263, 282—284, 286 Microsatellite markers 425—427 Immunoglobulin G, heavy chain 291 Minisatellite markers 425 Immunoglobulin M 53, 263, 283 Mononucleotides 111 Immunoglobulins 200, 248, 252, 253, 263, 268, 283, 4-Morpholinoethanesulphonic acid 7 287, 348 4-Morpholinopropanesulphonic acid 7 Immunoglobulins, light chain 291 Mucins 263, 275 Immunoglobulins, oligoclonal 284, 286, 290 Mutant proteins 407-418 Immunoglobulins, polyclonal 286 Mutations, detection 439-442 Informative markers 437, 438 Myelin basic protein 290 Insulin 128, 138-140, 143, 160, 163 Myelin proteins 294 Intracellular proteins, polymorphism 409 Myoglobin 93, 104, 338 Intrathecal modified C1S factor 291 Myosin 48, 181, 339, 340 Iodide 143, 166 NADPH-dependent diaphorase 409 452 Nerve growth factor 263 Proline-rich proteins, isoforms 270 Neuron-specific enolase 291, 294 Promotor-binding proteins 375 Neutral lipids 206 Properdin factor 409 Nitrate 7 Protective protein 411 NM.-IF fraction 396, 397 Protein a 340 Non-binding proteins 375 Protein b 340 Non-histone proteins 375 B-Protein 213 Nuclear antigens, proliferation cell, see Cyclin Protein C 216 Nuclear matrix proteins 389-404 Protein ‘“e’”’ 340 Nuclear matrix proteins, tissue-specific 400, 402 Protein S-100a, 340 Nuclear matrix proteins, tumor-specific 403 #,-Proteinase inhibitor 238 Nuclear proteins, proliferation-associated 377 Protein mapping 43-58 Nuclear proteins, tumour-associated 368, see also Proteins 11, 100—108 Proteins, neoplastic Proteins, brain tumour-associated 378 Nucleotides 191 Proteins, caries-related 271 Oesophageal carcinoma-associated proteins 378 Proteins, cerebrospinal fluid 281-294 Oligoclonal antibodies 285, 294 Proteins, chromosomal 375 Oligonucleotides 109, 428 Proteins, colon carcinoma-specific 382 Oligothymidylic acids 113 Proteins, connective tissue disorder-related 273 Ornithine 186 Proteins, contractile 339, 340 Orosomucoid, see «,-Acid glycoprotein Proteins, detection 175-194 Ovalbumin 191 Proteins, glomerular patterns 249, 250 Oxytocin 142, 143 Proteins, human heart 56 (2-O-Met-Tyr)Oxytocin 142 Proteins, human plasma 48 Pepsin 179 Proteins, infarction-related 323—340 Pepsinogen 179 Proteins, infectious diseases-related 54 Peptidase 409 Proteins, [?°S]methionine-labelled 50 Peptidase C 409 Proteins, mitochondrial 374, 378, 380 Peptidase D 409 Proteins, neoplastic 52, 53, 367-385, see also indi- Peptide mapping 108 vidual tumour-associated or tumor-specific Peptide polymorphism 51 proteins Peptides 96-100, 123-170 Proteins, polymorphic 270 Peptides, N-protected 139, 160 Proteins, rheumatoid arthritis-specific 269, 272 Peptides, synthetic 136-140, 153, 154 Proteins, ribosomal 372 Phenols 117 Proteins, salivary 220, 261-277 Phenylalanine 77, 96, 97 Proteins, seminal vesicle 399-401 Phenylalanine, enantiomers 90 Proteins, serum 55, 197—224, 288, 291, 375 Phosphoglucomutase 200, 215, 299, 409 Proteins, Sjorgen syndrome-specific 269, 272, 274 Phosphoglucomutase, isoenzymes 305-312 Proteins, tubular patterns 249, 250 Phosphoglucomutase, isoforms 215 Proteins, tumour-associated 371, 375, 379, 384 Phosphogluconate dehydrogenase 299, 409 Proteins, tumour-specific 276, 379, 382, see also Phospholipids 205, 206 Proteins, neoplastic Phosphoproteins 262, 373, 380, 400 Proteins, uremic 54 Phosphorylase 191 Proteins, urinary 54, 243-257 Piperidine 145, 166 Proteins, ventral prostate 399-401 Plasminogen 48 Proteolipid protein 410 Polycytidines 109, 110 Prothrombin 48, 291 Poly(L-lysine) 179 Protirelin 141, 142, 161 Polynucleotides 111, 112 Pyridine 145, 166 Polypeptide hormones 263 Radiopharmaceuticals 116 Polysaccharides 184 R-binder, see Cobalamin-binding proteins Potassium 7 Remestyp 167 Prealbumin 215, 284, 290, 291, 293 Restriction fragment length polymorphisms 408 Prealbumin, thyroxine-binding 48 Restriction fragment polymorphisms 424, 425 Proinsulin 140, 163 Retinol-binding protein 48, 291 Proline 96—98, 186 RFLP, see Restriction fragment polymorphisms Proline-rich proteins 262—265, 267, 268, 270, 271, Riboflavin 188 Zia 453 Ribonuclear proteins 395 Transferrin 47, 48, 106, 200, 216, 218, 219, 238, 249, Ribonuclease A 179 255, 257, 284, 290, 291, 299, 409 Ribonucleases 106 Transferrin, isoforms 217—219, 238 RNA 184, 390, 392-394, 399, 403 Transthyretin, see Prealbumin hnRNA 394, 396 Transthyretin, dimer 291 snRNA 403 Transthyretin-related protein 289, 291 RNA polymerases 394 Triamcinolone 114 RNase A 179 Triamcinolone acetonide 114 Saralasin 142, 161 Triethylamine 145, 166 Secretin 142 Trifluoroacetate 143, 166 Secretory component 263 Triglycerides 205, 206 Serine 77, 96-98, 186 Triglycylvasopressin 142 Serum albumin 178, 188, 191 Trimethylamine 145, 166 Serum glycoproteins 230 Trimethylphenylammonium iodide 85 Serum proteins, see Proteins, serum Tripeptides 153, 154, 165, 167 Sialoglycoproteins 184 Triphosphate 112 Siderophilin, see Transferrin 218 Tris 7, 9 Sodium 7 Tropomyosin 340 Somatostatin 142, 162 Troponin C 188 Soybean trypsin inhibitor 249 Trypsin 141, 179 Statherin 263 Trypsin inhibitor 137, 138, 142, 157, 162, 191, 395 Structural proteins 370 Trypsinogen 102 Substance P 142, 161 Tryptic fragments 136 S-Subunit, see B-Protein Tryptophan 77, 95, 96 Sulphate 7 Tryptophan, enantiomers 91 Sulphated glycoproteins 263 Tyrosine 77, 93, 96-98, 186 Tamm-Horsfall mucoprotein 247, 252 N?-Tyrosinyl-N°-tyrosinyllysine 4160 Taurine 156 Uridine monophosphate kinase 409 Tetrabutylammonium hydroxide 85 Urine profiling 117 Tetraethylammonium perchlorate 85 Uromucoid, see Tamm-Horsfall glycoprotein Tetramethylammonium 166 Valine 77, 96-98 Tetramethylammonium bromide 85 Valine, enantiomers 90 Tetrapeptides 159 Vasoactive intestinal peptide 162 Tetrapropylammonium hydroxide 85 Vasointestinal peptide 141 Threonine 77, 97, 98 Vasopressin 143, 145 Thyrotropin-releasing hormone 160 (1-Mpa-8-p-Arg)Vasopressin 142 p-Toluenesulphonate 143, 166 Vasp venoms 170 B-Trace protein 289-291 Very-low-density lipoproteins 205 Transcalciferin 263 Vitamin D-binding protein 409 Zinc-binding proteins 381