Journal of Cell Biology 2001: Vol 152 Table of Contents

7 Pages·2001·0.39 MB·English

Contents:
Volume 152, Number 1, January 8, 2001
In Brief 97 Targeting Pyk2 to pi-integrin-containing focal
Wnt inhibits apoptosis. contacts rescues fibronectin-stimulated signaling
Esplp triggers both phases of anaphase. and haptotactic motility defects of focal adhesion
Calreticulin and a termination factor in nuclear kinase-null cells.
export. C. K. Klingbeil, C.R. Hauck. D.A. Hsia. K.C. Jones.
Proteomics for phagosomes. S.R. Reider, and D.D. Schlaepfer
W.A. Wells 111 Differential localization of Rho GTPases in live
cells; Regulation by hypervariable regions and
Mini-Review
RhoGDI binding.®
FI Molecular machines; Putting the pieces together.
D. Michaelson. J. Silletti, G. Murphy, P. D'Eustachio,
E. Nogales and N. Grigorieff M. Rush, and M.R. Philips
Regular Articles 127 Calreticulin is a receptor for nuclear export.
1 Wasp, the Drosophila Wiskott-Aldrich syndrome J.M. Holaska, B.E. Black. D.C. Love. J.A. Hanover,
gene homologue, is required for cell fate J. Leszyk, and B.M. Paschal
decisions mediated by Notch signaling.
141 NXTl is necessary for the terminal step of
S. Ben-Yaacov. R. Le Borgne, I. Abramson, Crml-mediated nuclear export.
F. Schweisguth. and E.D. Schejter
B.E. Black. J.M. Holaska. L. Levesque.
15 Replication origins in Xenopus egg extract are B. Ossareh-Nazari, C. Gwizdek. C. Dargemont,
5-15 kilobases apart and are activated in clusters and B.M. Paschal
that fire at different times. 157 The telomerase/vault-associated protein TEPl is
J.J. Blow, P.J. Gillespie, D. Francis, and D.A. Jackson required for vault RNA stability and its
association with the vault particle.
27 A novel role of the budding yeast separin Espl
in anaphase spindle elongation; Evidence that V. A. Kickhoefer, Y. Liu, L.B. Kong, B.E. Snow,
P.L. Stewart. L. Harrington, and L.H. Rome
proper spindle association of Espl is regulated
by Pdsl. 165 The phagosome proteome; Insight into
S. Jensen, M. Segal, D.J. Clarke, and S.I. Reed phagosome functions.
J. Garin, R. Diez, S. Kieffer, J.-F. Dermine, S. Duclos,
41 Vacuolar storage proteins are sorted in the
E. Gagnon, R. Sadoul. C. Rondeau, and M. Desjardins
cis-cisternae of the pea cotyledon Golgi
apparatus. 181 Cbl associates with Pyk2 and Src to regulate Src
kinase activity, ayPs integrin-mediated signaling,
S. Hillmer, A. Movafeghi, D.G. Robinson, and G. Hinz
cell adhesion, and osteoclast motility.
51 Membrane recruitment of Aut7p in the
A. Sanjay. A. Houghton, L. Neff, E. DiDomenico,
autophagy and cytoplasm to vacuole targeting C. Bardelay, E. Antoine, J. Levy. J. Gailit, D. Bowtell,
pathways requires Autlp, Aut2p, and the W. C. Horne, and R. Baron
autophagy conjugation complex.
197 Mitotic spindle integrity and kinetochore
J. Kim, W.-P. Huang, and D.J. Klionsky function linked by the Duo Ip/Dam Ip complex.
65 Integrin activation by regulated dimerization and I.M. Cheeseman, M. Enquist-Newman,
oligomerization of platelet endothelial cell T. Miiller-Reichert. D.G. Drubin. and G. Barnes
adhesion molecule (PECAM)-1 from within the
213 The Sari GTPase coordinates biosynthetic cargo
cell, selection with endoplasmic reticulum export site
T. Zhao and P.J. Newman assembly.®
75 A functional interaction between the survival M. Aridor, K.N. Fish, S. Bannykh, J. Weissman,
T.H. Roberts. J. Lippincott-Schwartz. and W.E. Balch
motor neuron complex and RNA polymerase II.
L. Pellizzoni. B. Charroux. J. Rappsilber, M. Mann, Report
and G. Dreyfuss
231 TANGLEDl; A microtubule binding protein
87 Wnt-1 signaling inhibits apoptosis by activating required for the spatial control of cytokinesis in
P-catenin/T cell factor-mediated transcription. maize.®
S. Chen, D.C. Guttridge, Z. You, Z. Zhang, A. Fribley, L.G. Smith, S.M. Gerttula, S. Han, and J. Levy
M. W. Mayo, J. Kitajewski, and C.-Y. Wang
®The online version of this article contains supplemental material.
iii
Volume 152, Number 2, January 22, 2001
In Brief 325 Negative regulation of Ros receptor tyrosine
kinase signaling: An epithelial function of the
Maintenance of mitochondrial DNA.
SH2 domain protein tyrosine phosphatase
Timing of DNA replication.
SHP-1.
Conserved mitotic spindle components identified.
Arterial injection of muscle-derived stem cells. H. Keilhack, M. Muller, S.-A. Bohmer, C. Frank.
Voltage-dependent anion channel in apoptosis. K.M. Weidner, W. Birchmeier, 1. Ligensa, A. Berndt,
H. Kosmehl. B. Gunther. T. Muller, C. Birchmeier,
A.W. Dove and Frank D. Bohmer
Comment 335 Intraarterial injection of muscle-derived
FI 1 Nuclear position leaves its mark on replication CD34^Sca-l^ stem cells restores dystrophin in
timing. mdx mice.
D.M. Gilbert Y. Torrente, J.-P Tremblay, F. Pisati. M. Belicchi,
B. Rossi. M. Sironi, F. Fortunato, M. El Fahime,
Regular Articles M.G. D'Angelo, N.J. Caron. G. Constantin. D. Paulin,
G. Scarlato, and N. Bresolin
237 Essential role of voltage-dependent anion
channel in various forms of apoptosis in 349 The NdcSOp complex from Saccharomyces
mammalian cells. cerevisiae contains conserved centromere
S. Shimizu, Y. Matsuoka, Y. Shinohara, Y. Yoneda, components and has a function in chromosome
and Y. Tsujimoto segregation.
251 Cortical Numlp interacts with the dynein P.A. Wigge and J.V. Kilmartin
intermediate chain Pad Ip and cytoplasmic 361 Convergence of ctyPs integrin- and macrophage
microtubules in budding yeast. colony stimulating factor-mediated signals on
M. Farkasovsky and H. Kiintzel phospholipase Cy in prefusion osteoclasts.
263 Activation of endogenous thrombin receptors I. Nakamura, L. Lipfert, G.A. Rodan, and L.T. Duong
causes clustering and sensitization of epidermal 375 A novel chromatin protein, distantly related to
growth factor receptors of Swiss 3T3 cells histone H2A, is largely excluded from the
without transactivation. inactive X chromosome.
M.F. Crouch, D.A. Davy, F.S. Willard, B.P. Chadwick and H.F. Willard
and L.A, Berven
385 The positioning and dynamics of origins of
275 Downregulation of an AIM-1 kinase couples
replication in the budding yeast nucleus.®
with megakaryocytic polyploidization of human
hematopoietic cells. P. Heun, T. Laroche, M.K. Raghuraman,
and S.M. Gasser
A. Kawasaki, I, Matsumura, J.-i, Miyagawa, S. Ezoe,
H, Tanaka, Y. Terada, M, Tatsuka, T, Machii, 401 Mmmlp, a mitochondrial outer membrane
H. Miyazaki, Y, Furukawa, and Y. Kanakura protein, is connected to mitochondrial DNA
(mtDNA) nucleoids and required for mtDNA
289 Biogenesis of porin of the outer mitochondrial
stability.®
membrane involves an import pathway via
receptors and the general import pore of the A.E. Aiken Hobbs, M. Srinivasan, J.M. McCaffery,
TOM complex. and R.E. Jensen
T. Krimmer, D. Rapaport, M.T. Ryan. C. Meisinger, Report
C.K. Kassenbrock, E. Blachly-Dyson, M. Forte,
411 Gradient of increasing affinity of importin p for
M.G. Douglas, W. Neupert, F.E. Nargang,
and N. Planner nucleoporins along the pathway of nuclear
import.
301 The role of macrophages in demyelinating
I. Ben-Efraim and L. Gerace
peripheral nervous system of mice
heterozygously deficient in PO. 419^ ADDITIONS AND CORRECTIONS
S. Carenini, M. Maurer, A. Werner, H. Blazyca, 421 ADDITIONS AND CORRECTIONS
K.V. Toyka, C.D. Schmid. G. Raivich, and R. Martini
423 ADDITIONS AND CORRECTIONS
309 The role of dynamin and its binding partners in
coated pit invagination and scission.
E. Hill. J. van der Kaay, C.P. Downes, and E. Smythe
iv
Volume 152, Number 3, February 5, 2001
In Brief 531 The cytokinesis gene KEULE encodes a Sec I
Stem cells and mosaic diseases. protein that binds the syntaxin KNOLLE.
A novel Seel gene in cytokinesis. F.F. Assaad, Y. Huet, U. Mayer, and G. Jurgens
How the extracellular matrix regulates anoikis.
545 PITX2 regulates procollagen lysyl hydroxylase
Dystroglycans in acetylcholine receptor
(PLOD) gene expression: Implications for the
clustering.
pathology of Rieger syndrome.
Hsc70 regulates clathrin-coated vesicle
disassembly. T.A. Hjalt. B.A. Amendt, and J.C. Murray
A.W. Dove 553 Functional differences in yeast protein disulfide
isomerases.
Regular Articles
P. N0rgaard. V. Westphal, C. Tachibana. L. Alspe,
425 Chromosome movement in mitosis requires B. Holst, and J.R. Winther
microtubule anchorage at spindle poles.®
563 Identification and characterization of an escorter
M.B. Gordon. L. Howard, and D.A. Compton
for two secretory adhesins in Toxoplasma gondii.
435 The dystroglycan complex is necessary for M. Reiss. N. Viebig, S. Brecht. M.-N. Fourmaux.
stabilization of acetylcholine receptor clusters at M. Soete. M. Di Cristina. J.F. Dubremetz.
neuromuscular junctions and formation of the and D. Soldati
synaptic basement membrane.
579 Cdc42Hs facilitates cytoskeletal reorganization
C. Jacobson. P.D. Cote. .S.G. Rossi, R.L. Rotundo, and neurite outgrowth by localizing the 58-kD
and S. Carbonetto insulin receptor substrate to filamentous actin.
451 A novel function of Saccharomyces cerevisiae S. Govind, R. Ko/.ma, C. Monfries, L. Lim.
CDC5 in cytokinesis. and S. Ahmed
S. Song and K.S. Lee 595 Distribution and function of AP-I clathrin
adaptor complexes in polarized epithelial cells.
471 A novel neural Wiskott-Aldrich syndrome
protein (N-WASP) binding protein, WISH, H. Fblsch. M. Pypaert. P. Schu, and 1. Mellman
induces Arp2/3 complex activation independent
607 Dominant-interfering hsc70 mutants disrupt
of Cdc42.
multiple stages of the clathrin-coated vesicle
M. Fukuoka. S. Suetsugu, H. Miki, K. Fukami, cycle in vivo.®
T. Endo, and T. Takenawa
S.L. Newmyer and S.L. Schmid
483 DIABLO promotes apoptosis by removing
621 Tortoise, a novel mitochondrial protein, is
MIHA/XIAP from processed caspase 9.
required for directional responses of
P.G. Ekert. J. Silke, C.J. Hawkins. A.M. Verhagen. Dictyostelium in chemotactic gradients.®
and D.L. Vaux
S. van Es, D. Wessels. D.R. Soil. J. Borleis,
491 Apical membrane localization of the and P.N. Devreotes
adenomatous polyposis coli tumor suppressor
633 Matrix attachment regulates Fas-induced
protein and subcellular distribution of the
apoptosis in endothelial cells: A role for c-Flip
|3-catenin destruction complex in polarized
and implications for anoikis.
epithelial cells.
F. Aoudjit and K. Vuori
A. Reinacher-Schick and B.M. Gumbiner
Reports
503 Erv4Ip and Erv46p: New components of COPII
vesicles involved in transport between the ER 645 Focal activation of a mutant allele defines the
and Golgi complex. role of stem cells in mosaic skin disorders.
S. Otte, W.J. Belden, M. Heidtman, J. Liu, . M.J. Arin. M.A. Longley, X.-J. Wang, and D.R. Roop
O.N. Jensen, and C. Barlowe
651 An inducible mouse model for epidermolysis
519 Two distinct Vps34 phosphatidylinositol bullosa simplex: Implications for gene therapy.
3-kinase complexes function in autophagy and T. Cao, M.A. Longley, X.-J. Wang, and D.R. Roop
carboxypeptidase Y sorting in Saccharomyces
cerevisiae.
A. Kihara. T. Noda, N. Ishihara, and Y. Ohsumi
Volume 152, Number 4, February 19, 2001
In Brief 753 Activation of nuclear factor kB and bcl-x
survival gene expression by nerve growth factor
Tyrosine phosphorylation of iKBa.
requires tyrosine phosphorylation of iKBa.
Visualizing autophagy.
MMPs as inhibitors of adipocyte differentiation. N.T. Bui, A. Livolsi, J.-F. Peyron, and J.H.M. Prehn
Degradation and aggregation of an
765 A novel 14-kilodalton protein interacts with the
amyloidogenic protein.
mitogen-activated protein kinase scaffold MPl
The ins and outs of karyopherins.
on a late endosomal/lysosomal compartment.®
A. W. Dove
W. Wunderlich. I. Fialka, D. Teis, A. Alpi, A. Pfeifer,
Comments R. G. Parton, F. Lottspeich, and L.A. Huber
FI7 Where Notch and Wnt signaling meet: The 777 The plasminogen activator inhibitor PAI-1
presenilin hub. controls in vivo tumor vascularization by
B. De Strooper and W. Annaert interaction with proteases, not vitronectin:
Implications for antiangiogenic strategies.
F21 Of yeast, mice, and men: Rab proteins and
K. Bajou, V. Masson, R.D. Gerard. P.M. Schmitt,
organelle transport.
V. Albert, M. Praus, L.R. Lund. T.L. Frandsen.
S.W. Deacon and V.l. Gelfand N. Brunner. K. Dano. N.E. Fusenig. U. Weidle,
G. Carmeliet, D. Loskutoff, D. Collen, P. Carmeliet,
Regular Articles J.M. Foidart, and A. Noel
657 Dissection of autophagosome formation using 785 Presenilin 1 negatively regulates (3-catenin/T cell
Apg5-deficient mouse embryonic stem cells.® factor/lymphoid enhancer factor-1 signaling
N. Mizushima. A. Yamamoto, M. Hatano, independently of ^-amyloid precursor protein
Y. Kobayashi, Y. Kabeya, K. Suzuki, T. Tokuhisa, and notch processing.
Y. Ohsumi, and T. Yoshimori
S. Soriano. D.E. Kang. M. Fu, R. Pestell,
669 Drosophila Aurora B kinase is required for N. Chevallier, H. Zheng, and E.H. Koo
histone H3 phosphorylation and condensin
795 Rab27a regulates the peripheral distribution of
recruitment during chromosome condensation
melanosomes in melanocytes.®
and to organize the central spindle during
cytokinesis. A.N. Hume, L.M. Collinson, A. Rapak, A.Q. Gomes.
C.R. Hopkins, and M.C. Seabra
R. Giet and D.M. Glover
809 Distinct protein sorting and localization to
683 Connection of the mitochondrial outer and inner premelanosomes, melanosomes, and lysosomes in
membranes by Fzol is critical for organellar pigmented melanocytic cells.®
fusion.
G. Raposo, D. Tenza, D.M. Murphy. J.F. Berson,
S. Fritz, D. Rapaport, E. Klanner, W. Neupert. and M.S. Marks
and B. Westermann
825 Rab27a is required for regulated secretion in
693 Stromelysin-1 regulates adipogenesis during cytotoxic T lymphocytes.®
mammary gland involution.
J. C. Stinchcombe, D.C. Barral, E.H. Mules, S. Booth,
C. M. Alexander, S. Selvarajan, J. Mudgett, A.N. Hume, L.M. Machesky, M.C. Seabra.
and Z. Werb and G.M. Griffiths
705 Hsp70 and antifibrillogenic peptides promote 835 Defective granule exocytosis in Rab27a-deficient
degradation and inhibit intracellular aggregation lymphocytes from Ashen mice.
of amyloidogenic light chains.
E.K. Haddad, X. Wu, J.A. Hammer III,
J. L. Dul, D.P. Davis. E.K. Williamson, F.J. Stevens, and P.A. Henkart
and Y. Argon
Reports
717 A specific role of phosphatidylinositol
843 Rab27a: A key to melanosome transport in
3-kinase 7: A regulation of autonomic Ca^^
human melanocytes.
oscillations in cardiac cells.
P. Bahadoran, E. Aberdam, F. Mantoux, R. Busca,
C. Bony, S. Roche, U. Shuichi. T. Sasaki, M.A. K. Bille, N. Yalman, G. de Saint-Basile,
Crackower. J. Penninger, H. Mano, and M. Puceat R. Casaroli-Marano, J.-P. Ortonne, and R. Ballotti
729 The karyopherin Kapl42p/Msn5p mediates 851 An essential role for the substrate-binding region
nuclear import and nuclear export of different of Hsp40s in Saccharomyces cerevisiae.
cargo proteins.
J.L. Johnson and E.A. Craig
K. Yoshida and G. Blobel
741 Plasminogen activator inhibitor 1 functions as a
urokinase response modifier at the level of cell
signaling and thereby promotes MCF-7 cell
growth.
D. J. Webb, K.S. Thomas, and S.L. Gonias
vi
Volume 152, Number 5, March 5, 2001
In Brief 959 Cargo of kinesin identified as JIP scaffolding
Oscillating actin. proteins and associated signaling molecules.
A cargo for kinesin. K.J. Verhey, D. Meyer. R. Deehan, J. Blenis,
Microtubules in the end-zone. B. J. Schnapp. T.A. Rapoport. and B. Margolis
Linking without signaling.
971 Regulation of CDC42 GTPase by proline-rich
A stretchy structure. tyrosine kinase 2 interacting with PSGAP, a
W.A. Wells novel pleckstrin homology and Src homology 3
domain containing rhoGAP protein.
Comments
X. -R. Ren, Q.-S. Du, Y.-Z. Huang. S.-Z. Ao, L. Mei,
F25 Kinesin delivers: Identifying receptors for motor
and W.-C. Xiong
proteins.
985 Evidence for a replication function of FFA-1, the
P.J. Hollenbeck
Xenopus orthologue of Werner syndrome
F29 Caveolin, cholesterol, and lipid droplets? protein,
G. van Meer C. -Y. Chen. J. Graham, and H. Yan
Regular Articles 997 Regulation of antioxidant metabolism by
857 a4-Integrin mediates neutrophil-induced free translation initiation factor 2a.
radical injury to cardiac myocytes. S. Tan, N. Somia, P. Maher, and D. Schubert
B.Y. Poon, C.A. Ward, C.B. Cooper, W.R. Giles, 1007 Drosophila integrin-linked kinase is required at
A.R. Burns, and P. Kubes
sites of integrin adhesion to link the cytoskeleton
867 Phosphatidylinositol 4,5-bisphosphate induces to the plasma membrane.
actin stress-fiber formation and inhibits C G. Zervas, S.L. Gregory, and N.H. Brown
membrane ruffling in CVl cells.
1019 Rop GTPase-dependent dynamics of
M. Yamamoto. D.H. Hilgemann, S. Feng. H. Bito,
tip-localized F-actin controls tip growth in pollen
H. Ishihara, Y. Shibasaki, and H.L. Yin
tubes.®
877 A novel interaction of the Golgi complex with
Y. Fu. G. Wu. and Z. Yang
the vimentin intermediate filament cytoskeleton.
1033 Protein kinase C activation promotes
Y.-s. Gao and E. Sztul
microtubule advance in neuronal growth cones
895 Cofactor requirements for nuclear export of Rev by increasing average microtubule growth
response element (RRE)- and constitutive lifetimes.®
transport element (CTE)-containing retroviral
N. Kabir, A.W. Schaefer, A. Nakhost, W.S. Sossin,
RNAs: An unexpected role for actin. and P. Forscher
W. Hofmann, B. Reichart, A. Ewald, E. Muller.
1045 The supramolecular organization of fibrillin-rich
I. Schmitt. R.H. Stauber, F. Lottspeich, B.M. Jockusch,
U. Scheer, J. Hauber, and M.-C. Dabauvalle microfibrils.
C. Baldock, A.J. Koster, U. Ziese, M.J. Rock,
911 Autocrine stimulation of human pancreatic
M.J. Sherratt, K.E. Kadler, C.A. Shuttleworth,
duct-like development by soluble isoforms of and C.M. Kielty
epimorphin in vitro.
1057 A caveolin dominant negative mutant associates
L. Lehnert, M.M. Lerch, Y. Hirai, M.-L. Kruse,
with lipid bodies and induces intracellular
W. Schmiegel, and H. Kalthoff
cholesterol imbalance.®
923 The Golgi-associated Hook3 protein is a member
A. Pol, R. Luetterforst. M. Lindsay. S. Heino,
of a novel family of microtubule-binding E. Ikonen, and R.G. Parton
proteins.
1071 Accumulation of caveolin in the endoplasmic
J. H. Walenta, A.J. Didier, X. Liu. and H. Kramer
reticulum redirects the protein to lipid storage
935 Rerlp, a retrieval receptor for endoplasmic droplets.
reticulum membrane proteins, is dynamically A.G. Ostermeyer, J.M. Paci. Y. Zeng, D.M. Lublin.
localized to the Golgi apparatus by coatomer,® S. Munro, and D.A. Brown
K. Sato, M. Sato, and A. Nakano 1079 Caveolin-2 is targeted to lipid droplets, a new
945 The localization of human cyclins B1 and B2 “membrane domain” in the cell.
determines CDKl substrate specificity and T. Fujimoto, H. Kogo, K. Ishiguro, K. Tauchi,
neither enzyme requires MEK to disassemble the and R. Nomura
Golgi apparatus.
V. M. Draviam, S. Orrechia, M. Lowe, R. Pardi,
and J. Pines
vii
/
1087 Mammalian Sprouty-1 and -2 are 1107 Deletion of murine SMN exon 7 directed to
membrane-anchored phosphoprotein inhibitors of skeletal muscle leads to severe muscular
growth factor signaling in endothelial cells. dystrophy.
M.-A. Impagnatiello, S. Weitzer, G. Gannon. C. Cifuentes-Diaz. T. Frugier, F.D. Tiziano,
A. Compagni. M. Gotten, and G. Christofori E. Lacene, N. Roblot, V. Joshi, M.H. Moreau,
and J. Melki
Reports
1115 Equine herpesvirus protein ElO induces
1099 The transcription coactivator CBP is a dynamic
membrane recruitment and phosphorylation of
component of the promyelocytic leukemia
its cellular homologue, bcl-10.
nuclear body.
M. Thome, O. Gaide, O. Micheau, F. Martinon,
F.-M. Boisvert. M.J. Kruhlak, A.K. Box. M.J. HendzG.
D. Bonnet, M. Gonzalez, and J. Tschopp
and D.P. Bazett-Jones
Volume 152, Number 6, March 19, 2001
In Brief 1197 The high mobility group (HMG) boxes of the
Angiostatin antagonizes angiomotin. nuclear protein HMGl induce chemotaxis and
Endostatin antagonizes itself, trimerized. cytoskeleton reorganization in rat smooth muscle
Integrins to the rescue. cells.
HMGl and atherosclerosis. B. Degryse. T. Bonaldi. P. Scaffidi, S. Muller,
M. Resnati, F. Sanvito, G. Arrigoni, and M.E. Bianchi
W.A. Wells
1207 Enhanced expression of the a7(31 integrin
Comment
reduces muscular dystrophy and restores
F35 Hold that line: Angiomotin regulates endothelial viability in dystrophic mice.®
cell motility.
D.J. Burkin, G.O. Wallace, K.J. Nicol, D.J. Kaufman,
B. R. Zetter and S.J. Kauftn-in
Regular Articles 1219 The NCl/endostatin domain of Caenorhabditis
1123 UGOl encodes an outer membrane protein elegans type XVIIl collagen affects cell migration
required for mitochondrial fusion. and axon guidance.
H. Sesaki and R.E. Jensen B. D. Ackley, J.R. Crew, H. Elamaa, T. Pihlajaniemi,
C. J. Kuo, and J.M. Kramer
1135 Diacylglycerol kinase ^ regulates Ras activation
1233 Oligomerization-dependent regulation of motility
by a novel mechanism.
and morphogenesis by the collagen XVIII
M.K. Topham and S.M. Prescott
NCl/endostatin domain.®
1145 Rac mediates cytoskeletal rearrangements and C.J. Kuo, K.R. LaMontagne, Jr., G. Garcia-Cardena,
increased cell motility induced by urokinase-type B.D. Ackley, D. Kalman, S. Park, R. Christofferson,
plasminogen activator receptor binding to J. Kamihara. Y.-H. Ding, K.-M. Lo, S. Gillies,
J. Folkman, R.C. Mulligan, and K. Javaherian
vitronectin.
L. Kjpller and A. Hall 1247 Angiomotin: An angiostatin binding protein that
regulates endothelial cell migration and tube
1159 An acidic motif retains vesicular monoamine
formation.
transporter 2 on large dense core vesicles.
B. Troyanovsky, T. Levchenko, G. M^nsson,
C. L. Waites, A. Mehta, P.K. Tan, G. Thomas, O. Matvijenko, and L. Holmgren
R.H. Edwards, and D.E. Krantz
1255 Budding yeast chromosome structure and
1169 A role for syndecan-1 in coupling fascin spike
dynamics during mitosis.
formation by thrombospondin-1.
C. G. Pearson, P.S. Maddox, E.D. Salmon,
J. C. Adams. N. Kureishy, and A.L. Taylor and K. Bloom
1183 Atypical protein kinase C is involved in the 1267 Cyclin E uses Cdc6 as a chromatin-associated
evolutionarily conserved PAR protein complex receptor required for DNA replication.®
and plays a critical role in establishing
L. Furstenthal, B.K. Kaiser, C. Swanson,
epithelia-specific junctional structures.® and P.K. Jackson
A. Suzuki, T. Yamanaka, T. Hirose, N. Manabe,
1279 Internal modification of U2 small nuclear
K. Mizuno, M. Shimizu, K. Akimoto, Y. Izumi,
T. Ohnishi, and S. Ohno (sn)RNA occurs in nucleoli of Xenopus oocytes.
Y.-T. Yu, M.-D. Shu, A. Narayanan, R.M. Terns,
M. P. Terns, and J.A. Steitz
1289 Glial growth factor/neuregulin inhibits Schwann 1307 Importin (3-mediated nuclear import of
cell myelination and induces demyelination. fibroblast growth factor receptor: Role in cell
G. Zanazzi, S. Einheber, R. Westreich, M.-J. Hannocks. proliferation.
D. Bedell-Hogan, M.A. Marchionni, and J.L. Salzer J.F. Reilly and P.A. Maher
Reports 1313 The Caenorhabditis elegans unc-78 gene encodes
1301 Oncogenic Ras-induced proliferation requires a homologue of actin-interacting protein 1
autocrine fibroblast growth factor 2 signaling in required for organized assembly of muscle actin
skeletal muscle cells. filaments.
Y.V. Fedorov, R.S. Rosenthal, and B.B. Olwin S. Ono